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Lawrence E. Mettler,Thomas G. Gregg,Henry E. Schaffer
Author : Lawrence E. Mettler,Thomas G. Gregg,Henry E. Schaffer Publisher : Benjamin-Cummings Publishing Company Page : 342 pages File Size : 43,8 Mb Release : 1988 Category : Medical ISBN : STANFORD:36105033052643
Population Genetics and Evolution by Lawrence E. Mettler,Thomas G. Gregg,Henry E. Schaffer Pdf
Self-contained and reader-friendly, this volume provides a balanced blend of evolutionary theory, population genetics, and systematics with an emphasis on the experimental approach.
This concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for students working in a laboratory setting or studying free-ranging populations.
Population Genetics and Evolution by Gerdina de Jong Pdf
At least since the 1940s neo-Darwinism has prevailed as the consensus view in the study of evolution. The mechanism of evolution in this view is natural selection leading to adaptation, working on a substrate of adapta tionally random mutations. As both the study of genetic variation in natural populations, and the study of the mathematical equations of selec tion are reckoned to a field called population genetics, population genetics came to form the core in the theory of evolution. So much so, that the fact that there is more to the theory of evolution than population genetics became somewhat obscured. The genetics of the evolutionary process, or the genetics of evolutionary change, came close to being all of evolutionary biology. In the last 10 years, this dominating position of population genetics within evolutionary biology has been challenged. In evolutionary ecology, optimization theory proved more useful than population genetics for interesting predictions, especially of life history strategies. From develop mental biology, constraints in development and the role of internal regula tion were emphasized. From paleobiology, a proposal was put forward to describe the fossil record and the evolutionary process as a series of punc tuated equilibria; thus exhorting population geneticists to give a plausible account of how such might come about. All these developments tend to obscure the central role of population genetics in evolutionary biology.
Population Genetics and Microevolutionary Theory by Alan R. Templeton Pdf
The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Population Genetics, Molecular Evolution, and the Neutral Theory by Motoo Kimura Pdf
One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Principles of Population Genetics by Daniel L. Hartl,Andrew G. Clark Pdf
Darwinian evolution in mendelian populations. Random genetic drift. Mutation and the neutral theory. Natural selection. Inbreeding and other forms of nonrandom mating. Population subdivision and migration. Molecular population genetics. Evolutionary genetics of quantitative characters. Ecological genetics and speciation.
Progress in Population Genetics and Human Evolution by Peter Donnelly Pdf
This book is devoted to the collection, interpretation and analysis of population genetic data. Among the topics included here are studies on human evolutionary history, molecular techniques for generating data, statistical and computational techniques for the interpretation of such data, and stochastic models for genealogy and population structure. The chapters reflect the close interaction between experimental molecular biologists and theoreticians. The book will be useful for specialists in the area, as well as mathematicians, statisticians, computer scientists and biologists wanting a brief overview of current problems in the field.
Population genetics is the mathematical investigation of the changes in the genetic structure of populations brought about by selection, mutation, inbreeding, migration, and other phenomena, together with those random changes deriving from chance events. These changes are the basic components of evolutionary progress, and an understanding of their effect is therefore necessary for an informed discussion of the reasons for and nature of evolution. It would, however, be wrong to pretend that a mathematical theory, depending as it must on a large number of simplifying assump tions, should be accepted unreservedly and that its conclusions should be accepted uncritically. No-one would pretend that in the event of disagreement between observation and mathematical prediction, the discrepancy is due to anything other than the inadequacy of the mathematical treatment. The biological world is, of course, far too complex for the study of population genetics to be simply a branch of applied mathematics, so that while we are concerned here with the mathematical theory, I have tried to indicate which of our results should continue to apply in a context wider than that in which they are formally derived. The difficulties involved in the joint discussions of mathematical and genetical problems are obvious enough. I have tried to aim this book rather more at the mathematician than at the geneticist, and for this reason a brief glossary of common genetical terms is included.
Introduction to Population Genetics by Richard Halliburton Pdf
Making the theory of population genetics relevant to readers, this book explains the related mathematics with a logical organization. It presents the quantitative aspects of population genetics, and employs examples of human genetics, medical evolution, human evolution, and endangered species. For an introduction to, and understanding of, population genetics.
Understanding Population Genetics by Torbjörn Säll,Bengt O. Bengtsson Pdf
An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow. Particular attention is given to the underlying assumptions and the mathematics used. The results are discussed and broadened out with relevant current implications. All topics feature questions with helpful answers. The book is intended for the reader who already knows some population genetics but requires a more comprehensive understanding. It is particularly suited to those who analyse genetic data and wish to better grasp what their results actually mean. It will also be helpful for those who wish to understand how population genetics contributes to the explanation of evolution. Or as the writers claim: If one wants to understand life – in all its improbable and amazing richness – one must start by understanding population genetics.
Theory of Population Genetics and Evolutionary Ecology by Joan Roughgarden Pdf
This is a reprint of a classic which synthesizes population, genetics, and population genetics to form one of the first books on evolutionary ecology. Written by one of the foremost authorities in the field, it is designed as an introduction useful to readers at various levels from diverse backgrounds. It features balanced, readable coverge of both elementary and advanced topics that are essential to those interested in evolutionary biology, ecology, animal behavior, sociobiology, and paleobiology.
Theoretical Aspects of Population Genetics. (MPB-4), Volume 4 by Motoo Kimura,Tomoko Ohta Pdf
To show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.
