Precision Molecular Pathology Of Prostate Cancer

Author : Brian D. Robinson,Juan Miguel Mosquera,Jae Y. Ro,Mukul Divatia
Publisher : Springer
Page : 570 pages
File Size : 49,8 Mb
Release : 2018-02-13
Category : Medical
ISBN : 9783319640969

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Precision Molecular Pathology of Prostate Cancer by Brian D. Robinson,Juan Miguel Mosquera,Jae Y. Ro,Mukul Divatia Pdf

This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) and Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.

Author : Donna E. Hansel,Seth P. Lerner
Publisher : Springer
Page : 243 pages
File Size : 47,6 Mb
Release : 2018-01-05
Category : Medical
ISBN : 9783319647692

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Precision Molecular Pathology of Bladder Cancer by Donna E. Hansel,Seth P. Lerner Pdf

This succinct yet comprehensive volume describes current and emerging concepts in molecular pathology of bladder cancer. Divided into two distinct sections, the first part focuses on the general principles of molecular findings in bladder cancer, while the second part focuses on the molecular changes associated with specific histologic subtypes. The volume also addresses such topics as molecular alterations in non-invasive and invasive disease, including bladder cancer variants as appropriate, emerging molecular classifiers of bladder cancer, and molecular associations to outcome and treatment. Written by experts in the field, Precision Molecular Pathology of Bladder Cancer is a valuable resource for those in the urologic community, including urologic pathologists, urologists, urologic oncologists and radiation oncologists, who treat and manage bladder cancer.

Author : Philip T. Cagle,Timothy Craig Allen,Mary Beth Beasley,Lucian R. Chirieac,Sanja Dacic,Alain C. Borczuk,Keith M. Kerr,Lynette M. Sholl,Bryce Portier,Eric H. Bernicker
Publisher : Springer
Page : 296 pages
File Size : 40,5 Mb
Release : 2017-11-23
Category : Medical
ISBN : 3319629409

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Precision Molecular Pathology of Lung Cancer by Philip T. Cagle,Timothy Craig Allen,Mary Beth Beasley,Lucian R. Chirieac,Sanja Dacic,Alain C. Borczuk,Keith M. Kerr,Lynette M. Sholl,Bryce Portier,Eric H. Bernicker Pdf

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions. Authored by experts in the field, Precision Molecular Pathology of Lung Cancer, Second Edition remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.

Author : Stefania Staibano
Publisher : Springer
Page : 0 pages
File Size : 51,7 Mb
Release : 2017-04-30
Category : Medical
ISBN : 9402402357

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Prostate Cancer: Shifting from Morphology to Biology by Stefania Staibano Pdf

The aim of this book will be to contribute to the education of a new generation of experts in urology, molecular biology, pathology and oncology, offering them sufficient knowledge in basic and translational research to be fluency in the web of interacting networks playing a role in prostate cancer development, progression, metastasis and drug-resistance.The volume will cover the latest innovative researches in prostate cancer, with particular emphasis to the state-of-the-art analysis technologies that are essential for the accurate identification of molecular targets for disease diagnosis, molecular mechanisms of tumorigenesis, markers for susceptibility, molecular-based prognostic prevision, characterization of biomarkers of drug efficacy and drug resistance, validation of new therapeutics and diagnostics. Current advancements on the intersecting data concerning transcriptomes, proteomes, the molecular techniques referred as "omes", will be reported and discussed.

Author : Sameek Roychowdhury,Eliezer M. Van Allen
Publisher : Springer Nature
Page : 196 pages
File Size : 50,5 Mb
Release : 2020-01-02
Category : Medical
ISBN : 9783030236373

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Precision Cancer Medicine by Sameek Roychowdhury,Eliezer M. Van Allen Pdf

Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.

Author : Michael T. Deavers,Donna M. Coffey
Publisher : Springer
Page : 286 pages
File Size : 55,8 Mb
Release : 2017-10-28
Category : Medical
ISBN : 9783319579856

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Precision Molecular Pathology of Uterine Cancer by Michael T. Deavers,Donna M. Coffey Pdf

This text provides a comprehensive review for practicing pathologists to understand the molecular biology, diagnostics, and predictive markers and implications for therapy of uterine cancer. While molecular based therapeutic strategies for uterine cancer are not as well developed as for some other organ sites, these are the most common gynecologic malignancies and there have been many important recent developments that are discussed in this volume. Comprehensive chapters address essential information about endometrial carcinoma, uterine mesenchymal tumors, and cervical carcinoma and include the pathogenesis of carcinoma and discuss molecular based classification, biomarkers, therapy, prevention, and hereditary cancers of the uterus. Precision Molecular Pathology of Uterine Cancer is a unique and one of a kind resource for practicing pathologists, pathologists in training and gynecologists.

Author : Ashraf Khan,Ian O. Ellis,Andrew M. Hanby,Ediz F. Cosar,Emad A. Rakha,Dina Kandil
Publisher : Springer
Page : 338 pages
File Size : 52,5 Mb
Release : 2015-08-12
Category : Medical
ISBN : 9781493928866

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Precision Molecular Pathology of Breast Cancer by Ashraf Khan,Ian O. Ellis,Andrew M. Hanby,Ediz F. Cosar,Emad A. Rakha,Dina Kandil Pdf

This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2. Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.

Author : Chen Liu
Publisher : Springer
Page : 271 pages
File Size : 45,7 Mb
Release : 2018-01-09
Category : Medical
ISBN : 9783319680828

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Precision Molecular Pathology of Liver Cancer by Chen Liu Pdf

This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC. Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.

Author : Philip T. Cagle,Timothy Craig Allen,Mary Beth Beasley,Lucian R. Chirieac,Sanja Dacic,Alain C. Borczuk,Keith M. Kerr,Lynette M. Sholl,Bryce Portier,Eric H. Bernicker
Publisher : Springer
Page : 296 pages
File Size : 51,5 Mb
Release : 2017-11-10
Category : Medical
ISBN : 9783319629414

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Precision Molecular Pathology of Lung Cancer by Philip T. Cagle,Timothy Craig Allen,Mary Beth Beasley,Lucian R. Chirieac,Sanja Dacic,Alain C. Borczuk,Keith M. Kerr,Lynette M. Sholl,Bryce Portier,Eric H. Bernicker Pdf

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these changes, providing updates and new insights on the background of lung cancer, testing methods, and the molecular pathology of specific cell types, including adenocarcinoma, squamous cell carcinoma, small cell carcinoma, and precursor and preinvasive lesions. Authored by experts in the field, Precision Molecular Pathology of Lung Cancer, Second Edition remains one of the few books that comprehensively covers the new molecular pathology of lung cancer and is a valuable resource for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, and thoracic radiologists.

Author : Genevieve M. Crane
Publisher : Springer Nature
Page : 434 pages
File Size : 43,7 Mb
Release : 2024-06-16
Category : Electronic
ISBN : 9783031468421

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Precision Molecular Pathology of Aggressive B-Cell Lymphomas by Genevieve M. Crane Pdf

Author : Victor G. Prieto
Publisher : Springer
Page : 136 pages
File Size : 51,6 Mb
Release : 2015-08-10
Category : Medical
ISBN : 9781493928613

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Precision Molecular Pathology of Dermatologic Diseases by Victor G. Prieto Pdf

This volume is a concise yet comprehensive resource for physicians dealing with, and interested in, the field of molecular pathology in dermatopathology. The book includes descriptions of the techniques and their application to cutaneous diseases and describes possible future techniques and their use in dermatopathology. Special emphasis is also given to the practical application of these techniques to particular situations illustrated by demonstrative cases. Written by experts in their fields, Precision Molecular Pathology of Dermatologic Diseases is of great value to pathologists, dermatologists, resident and fellows, internists, and general practitioners who deal with dermatologic diseases.

Author : S. David Hudnall,Ralf Küppers
Publisher : Springer
Page : 236 pages
File Size : 52,6 Mb
Release : 2017-12-09
Category : Medical
ISBN : 9783319680941

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Precision Molecular Pathology of Hodgkin Lymphoma by S. David Hudnall,Ralf Küppers Pdf

This text provides a comprehensive and up-to-date overview of Hodgkin lymphoma. The volume reviews every facet of the cancer in great detail, including pathology, pathobiology, molecular genetics, microenvironment, epidemiology, treatment, and new therapeutic advances. The specific role of the lymphoma microenvironment is addressed, and the relationship of Hodgkin lymphoma to related non-Hodgkin lymphomas is covered as well. Written by experts in the field, Precision Molecular Pathology of Hodgkin Lymphoma is a valuable resource for oncologists, surgeons, pathologists, clinical trainees, and investigators engaged in the diagnosis, treatment, and research studies of this lymphoid neoplasm.

Author : Larissa V. Furtado,Aliya N. Husain
Publisher : Springer
Page : 360 pages
File Size : 52,8 Mb
Release : 2018-08-01
Category : Medical
ISBN : 9783319896267

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Precision Molecular Pathology of Neoplastic Pediatric Diseases by Larissa V. Furtado,Aliya N. Husain Pdf

This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care. Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.

Author : Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter
Publisher : Springer
Page : 670 pages
File Size : 45,6 Mb
Release : 2016-09-01
Category : Medical
ISBN : 9783319351537

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Pathology and Epidemiology of Cancer by Massimo Loda,Lorelei A. Mucci,Megan L. Mittelstadt,Mieke Van Hemelrijck,Maura Bríd Cotter Pdf

This book integrates the disciplines of cancer pathology and epidemiology to provide a synergistic and complementary approach to understanding the molecular mechanisms of cancer. This book provides relevant information on the diagnostic, prognostic and predictive molecular pathology of cancer. Epidemiological studies, including descriptive epidemiology, risk factors and molecular mechanisms of disease inform on the etiology and progression of cancer. The text concentrates on major cancers that are currently prevalent and those for which substantial molecular, pathological and epidemiological data is available. Each section is designed to provide an overview of that cancer type in terms of basic biology, review the current epidemiological data surrounding that cancer type and provide information on common practices and challenges related to the molecular pathology of that cancer type. Several relevant techniques in molecular pathology, which facilitate diagnosis and treatment are also explored. Pathology and Epidemiology of Cancer provides a succinct and comprehensive overview of multiple cancer types to guide clinicians during patient care and to guide scientists for innovations in research. It represents an integral resource for pathologists, epidemiologists, medical students as well as translational, basic and clinical science researchers who are all working to progress the field of cancer in terms of diagnosis, treatment and prevention.

Author : Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz
Publisher : Walter de Gruyter
Page : 220 pages
File Size : 45,8 Mb
Release : 2013-05-22
Category : Medical
ISBN : 9783110807271

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Molecular Biology of Prostate Cancer by Manfred Wirth,J. E. Altwein,B. Schmitz-Dräger,S. Kuptz Pdf