Principles Of Clinical Pharmacology

Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publisher : Elsevier
Page : 568 pages
File Size : 53,5 Mb
Release : 2011-04-28
Category : Medical
ISBN : 0080466427

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Principles of Clinical Pharmacology by Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey Pdf

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Author : Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson Jr.
Publisher : Academic Press
Page : 764 pages
File Size : 49,9 Mb
Release : 2021-10-16
Category : Medical
ISBN : 9780128198841

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Atkinson's Principles of Clinical Pharmacology by Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson Jr. Pdf

Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Author : Shiew-Mei Huang,Juan J.L. Lertora,Arthur J. Atkinson Jr.
Publisher : Academic Press
Page : 649 pages
File Size : 45,7 Mb
Release : 2012-09-18
Category : Medical
ISBN : 9780123854728

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Principles of Clinical Pharmacology by Shiew-Mei Huang,Juan J.L. Lertora,Arthur J. Atkinson Jr. Pdf

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III

Author : Harold Kalant,Walter H. E. Roschlau,Edward M. Sellers,Edward M. Seller
Publisher : Oxford University Press, USA
Page : 984 pages
File Size : 43,9 Mb
Release : 1985
Category : Language Arts & Disciplines
ISBN : UOM:39015010167701

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Principles of Medical Pharmacology by Harold Kalant,Walter H. E. Roschlau,Edward M. Sellers,Edward M. Seller Pdf

Balanced, readable, and authoritative, this volume provides a well-tested introduction to basic pharmacology for students of medicine, dentistry, pharmacy, and allied health fields. The fourth edition includes new chapters on drug-induced carcinogenesis and teratogenesis, adverse drug reactions, perinatal pharmacology, geriatric pharmacology, and behavioral pharmacology. The material on clincal pharamacology and therapeutics, formerly a separate section, has been integrated into various chapters throughout the text, where it amplifies and illustrates the basic pharamcological concepts. With over 70 chapters, 46 contributors, an improved format and many new illustrations, the new edition provides a lucid, step-by-step introduction to medical pharmacology.

Author : David E. Golan,Armen H. Tashjian,Ehrin J. Armstrong
Publisher : Lippincott Williams & Wilkins
Page : 978 pages
File Size : 46,9 Mb
Release : 2011-12-15
Category : Medical
ISBN : 9781608312702

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Principles of Pharmacology by David E. Golan,Armen H. Tashjian,Ehrin J. Armstrong Pdf

Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty

Author : Gerard A. McKay,Matthew R. Walters,Neil D. Ritchie
Publisher : John Wiley & Sons
Page : 313 pages
File Size : 47,7 Mb
Release : 2021-01-26
Category : Medical
ISBN : 9781119599951

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Clinical Pharmacology and Therapeutics by Gerard A. McKay,Matthew R. Walters,Neil D. Ritchie Pdf

A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease. Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making. Presents an up-to-date review of drug use across all major clinical disciplines Offers a timely overview of clinical drug trials and development Provides new clinical scenarios to relate chapter content to real-life application Contains colour-coded “Key Points” and “Prescribing Points” to highlight important information Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrations Lecture Notes: Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.

Author : David J. Kerr,Daniel G. Haller,Cornelis J. H. van de Velde,Michael Baumann
Publisher : Oxford University Press
Page : 832 pages
File Size : 52,8 Mb
Release : 2016-01-28
Category : Medical
ISBN : 9780191065118

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Oxford Textbook of Oncology by David J. Kerr,Daniel G. Haller,Cornelis J. H. van de Velde,Michael Baumann Pdf

Now in paperback, the Oxford Textbook of Oncology reflects current best practice in the multidisciplinary management of cancer, written and edited by internationally recognised leaders in the field. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

Author : Robert F. Maronde
Publisher : Springer Science & Business Media
Page : 528 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461248644

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Topics in Clinical Pharmacology and Therapeutics by Robert F. Maronde Pdf

Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions.

Author : Derek G. Waller,Tony Sampson
Publisher : Elsevier Health Sciences
Page : 741 pages
File Size : 47,6 Mb
Release : 2013-08-07
Category : Medical
ISBN : 9780702055034

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Medical Pharmacology and Therapeutics E-Book by Derek G. Waller,Tony Sampson Pdf

This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice

Author : Jill E. Maddison,Stephen W. Page,David B. Church
Publisher : Elsevier Health Sciences
Page : 600 pages
File Size : 47,9 Mb
Release : 2008
Category : Medical
ISBN : 9780702028588

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Small Animal Clinical Pharmacology by Jill E. Maddison,Stephen W. Page,David B. Church Pdf

Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text

Author : James M. Olson
Publisher : Medmaster
Page : 186 pages
File Size : 52,7 Mb
Release : 1997
Category : Medical
ISBN : UOM:39015062492239

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Clinical Pharmacology Made Ridiculously Simple by James M. Olson Pdf

The book blendes the essentials of basic pharmacology and clinical pharmacology so that the transition from classroom to hospital is less abrupt. Students report that the book is most effective when lecture notes are written directly on the tables and margins, providing a single, concise guide for finals and the National Boards.

Author : Kenneth L. Melmon,Howard F. Morrelli
Publisher : Unknown
Page : 718 pages
File Size : 53,8 Mb
Release : 1975
Category : Electronic
ISBN : OCLC:1230116121

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Clinical Pharmacology by Kenneth L. Melmon,Howard F. Morrelli Pdf

Author : D. R. Laurence,P. N. Bennett,M. J. Brown
Publisher : Unknown
Page : 710 pages
File Size : 49,6 Mb
Release : 1997
Category : Clinical pharmacology
ISBN : 7030077237

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Clinical Pharmacology by D. R. Laurence,P. N. Bennett,M. J. Brown Pdf

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 50,6 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Harold Kalant,Denis Michael Grant,Jane Mitchell
Publisher : Saunders Canada
Page : 1050 pages
File Size : 54,6 Mb
Release : 2007
Category : Medical
ISBN : NWU:35557000139558

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Principles of Medical Pharmacology by Harold Kalant,Denis Michael Grant,Jane Mitchell Pdf

This edition includes new case studies, overview chapters on second messenger systems and the nervous and cardiovascular systems, and sections on topics such as drug-resistant TB and pharmacogenetics.