Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 40,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181
Molecular Biology of The Cell
Bruce Alberts
Protein Function
Protein Function Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Protein Function book. This book definitely worth reading, it is an incredibly well-written.
Fundamentals of Protein Structure and Function
Engelbert Buxbaum
Author : Engelbert Buxbaum
Publisher : Springer
Page : 521 pages
File Size : 45,5 Mb
Release : 2015-11-27
Category : Science
ISBN : 9783319199207
Fundamentals of Protein Structure and Function by Engelbert Buxbaum Pdf
This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.
The Role of Protein and Amino Acids in Sustaining and Enhancing Performance
Institute of Medicine,Committee on Military Nutrition Research
Author : Institute of Medicine,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 448 pages
File Size : 41,9 Mb
Release : 1999-09-15
Category : Technology & Engineering
ISBN : 9780309172813
The Role of Protein and Amino Acids in Sustaining and Enhancing Performance by Institute of Medicine,Committee on Military Nutrition Research Pdf
It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Protein Structure and Function
Gregory A. Petsko,Dagmar Ringe
Author : Gregory A. Petsko,Dagmar Ringe
Publisher : New Science Press
Page : 220 pages
File Size : 48,9 Mb
Release : 2004
Category : Proteins
ISBN : 9780878936632
Protein Structure and Function by Gregory A. Petsko,Dagmar Ringe Pdf
Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.
From Protein Structure to Function with Bioinformatics
Daniel John Rigden
Author : Daniel John Rigden
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 48,5 Mb
Release : 2008-12-11
Category : Science
ISBN : 9781402090585
From Protein Structure to Function with Bioinformatics by Daniel John Rigden Pdf
Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of protein structures, often those of proteins about which little is known of function. These initiatives have, in turn, stimulated the massive development of novel methods for prediction of protein function from structure. Since model structures may also take advantage of new function prediction algorithms, the first part of the book deals with the various ways in which protein structures may be predicted or inferred, including specific treatment of membrane and intrinsically disordered proteins. A detailed consideration of current structure-based function prediction methodologies forms the second part of this book, which concludes with two chapters, focusing specifically on case studies, designed to illustrate the real-world application of these methods. With bang up-to-date texts from world experts, and abundant links to publicly available resources, this book will be invaluable to anyone who studies proteins and the endlessly fascinating relationship between their structure and function.
Proteins
David Whitford
Author : David Whitford
Publisher : John Wiley & Sons
Page : 544 pages
File Size : 50,7 Mb
Release : 2013-04-25
Category : Science
ISBN : 9781118685723
Proteins by David Whitford Pdf
Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.
Frontiers in Protein Structure, Function, and Dynamics
Dev Bukhsh Singh,Timir Tripathi
Author : Dev Bukhsh Singh,Timir Tripathi
Publisher : Springer Nature
Page : 458 pages
File Size : 40,9 Mb
Release : 2020-07-02
Category : Science
ISBN : 9789811555305
Frontiers in Protein Structure, Function, and Dynamics by Dev Bukhsh Singh,Timir Tripathi Pdf
This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
Protein Function
Thomas E. Creighton
Author : Thomas E. Creighton
Publisher : Oxford University Press, USA
Page : 334 pages
File Size : 45,8 Mb
Release : 1989
Category : Science
ISBN : STANFORD:36105003090201
Protein Function by Thomas E. Creighton Pdf
Introduction to Protein Science
Arthur Lesk
Author : Arthur Lesk
Publisher : Oxford University Press
Page : 476 pages
File Size : 54,7 Mb
Release : 2010-03-25
Category : Education
ISBN : 9780199541300
Introduction to Protein Science by Arthur Lesk Pdf
Starting by describing the structure of proteins and explaining how these structures can be studied, this book goes on to illustrate the wide range of protein functions by showing how the shape of a protein is intimately linked to its function.
Protein Bioinformatics
M. Michael Gromiha
Author : M. Michael Gromiha
Publisher : Academic Press
Page : 349 pages
File Size : 52,8 Mb
Release : 2011-04-21
Category : Science
ISBN : 9780123884244
Protein Bioinformatics by M. Michael Gromiha Pdf
One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most important bioinformatics tools available today for protein analysis, interpretation and prediction. Students and researchers of biotechnology, bioinformatics, proteomics, protein engineering, biophysics, computational biology, molecular modeling, and drug design will find this a ready reference for staying current and productive in this fast evolving interdisciplinary field. Explains all aspects of proteins including sequence and structure analysis, prediction of protein structures, protein folding, protein stability, and protein interactions Presents a cohesive and accessible overview of the field, using illustrations to explain key concepts and detailed exercises for students.
New Approaches of Protein Function Prediction from Protein Interaction Networks
Jingyu Hou
Author : Jingyu Hou
Publisher : Academic Press
Page : 124 pages
File Size : 43,8 Mb
Release : 2017-01-13
Category : Mathematics
ISBN : 9780128099445
New Approaches of Protein Function Prediction from Protein Interaction Networks by Jingyu Hou Pdf
New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks. Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction. Provides innovative approaches and new developments targeting key issues in protein function prediction Presents heuristic ideas for further research in this challenging area
Protein Structure — Function Relationship
D.L. Smith,Z.H. Zaidi
Author : D.L. Smith,Z.H. Zaidi
Publisher : Springer Science & Business Media
Page : 291 pages
File Size : 55,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461303596
Protein Structure — Function Relationship by D.L. Smith,Z.H. Zaidi Pdf
Although many pursue understanding of the relationship between protein structure and function for the thrill of pure science, the pay-off in a much broader sense is the ability to manipulate the Earth's chemistry and biology to improve the quality of life for mankind. Immediately goals of this area of research include identification of the life-supporting functions of proteins, and the fundamental forces that facilitate these functions. Upon reaching these goals, we shall have the understanding to direct and the tools required to implement changes that will dramatically improve the quality of life. For example, under standing the chemical mechanism of diseases will facilitate development of new therapeutic drugs. Likewise, understanding of chemical mechanisms of plant growth will be used with biotechnology to improve food production under adverse climatic conditions. The challenge to understand details of protein structure/function relationships is enormous and requires an international effort for success. To direct the chemistry and biology of our environment in a positive sense will require efforts from bright, imaginative scientists located throughout the world. Although the emergence of FAX, e-mail, and the World Wide Web has revolutionized international communication, there remains a need for scientists located in distant parts of the world to occasionally meet face to face.
Protein Turnover and Lysosome Function
Harold L. Segal,Darrell J. Doyle
Author : Harold L. Segal,Darrell J. Doyle
Publisher : Academic Press
Page : 811 pages
File Size : 44,5 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483220192
Protein Turnover and Lysosome Function by Harold L. Segal,Darrell J. Doyle Pdf
Protein Turnover and Lysosome Function comprises the proceedings of a symposium under the same title held at the State University of New York at Buffalo on August 21-26, 1977. The book discusses mechanisms of protein turnover, as well as the identification and characterization of intracellular proteases. The text also describes the internalization of macromolecules into the intracellular digestive system; the types of specificity entailed; and the fate of the membrane material involved in the vacuolization process. Biochemists, pathologists, cell biologists, molecular biologists, and physiologists will find the book invaluable.
Committee on Military Nutrition Research
Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research
Author : Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research
Publisher : National Academies Press
Page : 303 pages
File Size : 49,5 Mb
Release : 1999-08-04
Category : Medical
ISBN : 9780309172769
Committee on Military Nutrition Research by Institute of Medicine,Food and Nutrition Board,Committee on Military Nutrition Research Pdf
The activities of the Food and Nutrition Board's Committee on Military Nutrition Research (CMNR, the committee) have been supported since 1994 by grant DAMD17-94-J-4046 from the U.S. Army Medical Research and Materiel Command (USAMRMC). This report fulfills the final reporting requirement of the grant, and presents a summary of activities for the grant period from December 1, 1994 through May 31, 1999. During this grant period, the CMNR has met from three to six times each year in response to issues that are brought to the committee through the Military Nutrition and Biochemistry Division of the U.S. Army Research Institute of Environmental Medicine at Natick, Massachusetts, and the Military Operational Medicine Program of USAMRMC at Fort Detrick, Maryland. The CMNR has submitted five workshop reports (plus two preliminary reports), including one that is a joint project with the Subcommittee on Body Composition, Nutrition, and Health of Military Women; three letter reports, and one brief report, all with recommendations, to the Commander, U.S. Army Medical Research and Materiel Command, since September 1995 and has a brief report currently in preparation. These reports are summarized in the following activity report with synopses of additional topics for which reports were deferred pending completion of military research in progress. This activity report includes as appendixes the conclusions and recommendations from the nine reports and has been prepared in a fashion to allow rapid access to committee recommendations on the topics covered over the time period.
Protein Families
Christine A. Orengo,Alex Bateman
Author : Christine A. Orengo,Alex Bateman
Publisher : John Wiley & Sons
Page : 566 pages
File Size : 46,9 Mb
Release : 2014-02-03
Category : Computers
ISBN : 9780470624227
Protein Families by Christine A. Orengo,Alex Bateman Pdf
New insights into the evolution and nature of proteins Exploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the major protein classification systems, including Pfam, Panther, SCOP, and CATH. Moreover, they'll discover how these systems can be used to understand the evolution of protein families as well as understand and predict the degree to which structural and functional information are shared between relatives in a protein family. Edited and authored by leading international experts, Protein Families offers new insights into protein families that are important to medical research as well as protein families that help us understand biological systems and key biological processes such as cell signaling and the immune response. The book is divided into three sections: Section I: Concepts Underlying Protein Family Classification reviews the major strategies for identifying homologous proteins and classifying them into families. Section II: In-Depth Reviews of Protein Families focuses on some fascinating super protein families for which we have substantial amounts of sequence, structural and functional data, making it possible to trace the emergence of functionally diverse relatives. Section III: Review of Protein Families in Important Biological Systems examines protein families associated with a particular biological theme, such as the cytoskeleton. All chapters are extensively illustrated, including depictions of evolutionary relationships. References at the end of each chapter guide readers to original research papers and reviews in the field. Covering protein family classification systems alongside detailed descriptions of select protein families, this book offers biochemists, molecular biologists, protein scientists, structural biologists, and bioinformaticians new insight into the evolution and nature of proteins.