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Author : Jian-bo Yang,Zhichao Xu,Wei Cai,Yong Li,Wing Lam
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 51,6 Mb
Release : 2023-06-27
Category : Science
ISBN : 9782832526552
Author : Frauke Gaedcke,Barbara Steinhoff
Publisher : CRC Press
Page : 208 pages
File Size : 43,9 Mb
Release : 2003
Category : Health & Fitness
ISBN : 0849310237
Herbal medicinal products are becoming more widely accepted as alternatives to medical prescriptions. Many physicians believe that herbal medicinal products are able to beneficially complement or even replace chemical medicines. Recognizing this, European institutions are pushing the harmonization of assessment criteria for herbal medicinal products. However, this kind of reevaluation of herbal medicinal products is combined with increased expectations of physicians, pharmacists, and patients with regard to quality, safety and efficacy. There are often uncertainties about the interpretation of basic terms related to the manufacture and quality of herbal medicinal products. Herbal Medicinal Products clarifies these uncertainties, increasing transparency in the herbal medicinal products market and supporting an adequate scientific discussion related to herbal medicinal products. It offers a complete survey on current scientific knowledge, as well as on legal basic requirements for the development, standardization, and licensing of herbal medicinal products.
Author : Dilip Ghosh,Pulok K. Mukherjee
Publisher : CRC Press
Page : 632 pages
File Size : 49,9 Mb
Release : 2019-07-18
Category : Medical
ISBN : 9781351741354
Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.
Author : Ravindra Kumar Pandey,Shiv Shankar Shukla,Amber Vyas,Vishal Jain,Parag Jain,Shailendra Saraf
Publisher : CRC Press
Page : 202 pages
File Size : 46,5 Mb
Release : 2018-07-03
Category : Health & Fitness
ISBN : 9780429682834
Due to the increase in the consumption of herbal medicine, there is a need to know which scientifically based methods are appropriate for assessing the quality of herbal medicines. Fingerprinting has emerged as a suitable technique for quality estimation. Chemical markers are used for evaluation of herbal medicines. Identification and quantification of these chemical markers are crucial for quality control of herbal medicines. This book provides updated knowledge on methodology, quality assessment, toxicity analysis and medicinal values of natural compounds.
Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 784 pages
File Size : 42,7 Mb
Release : 2019-05-30
Category : Science
ISBN : 9780128133989
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Author : Pulok K. Mukherjee
Publisher : Elsevier
Page : 858 pages
File Size : 49,6 Mb
Release : 2022-07-12
Category : Business & Economics
ISBN : 9780323984560
Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Author : Iris F. F. Benzie,Sissi Wachtel-Galor
Publisher : CRC Press
Page : 500 pages
File Size : 55,7 Mb
Release : 2011-03-28
Category : Health & Fitness
ISBN : 9781439807163
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef
Author : Pulok K. Mukherjee,Peter J. Houghton
Publisher : Unknown
Page : 0 pages
File Size : 55,6 Mb
Release : 2009
Category : Health & Fitness
ISBN : 0853697515
"This book presents a structural approach to the evaluation of herbal medicinal products for quality, safety and efficacy. There has been an enormous growth in the market for herbal medicinal products in the last twenty five years. However the rediscovery of natural substances with therapeutic potential has raised questions of quality, safety and efficacy on the part of the consumer and also from health professionals. This book brings together current thinking and practice in these areas highlighting current research. In the light of increasing legislation to enforce better standards for these products and the demand by legislators and the public for assurance of safe and effective use, this book seeks to provide a state-of-the-art review, which informs and guides those who seek to promote their use. This book also gives an overview of the place of ethno pharmacology in the development of herbal medicinal products and discusses good agricultural and collection practices, marker analysis and stability testing which contribute to assessment of good quality of these materials." -- Publisher description.
Author : World Health Organization
Publisher : World Health Organization
Page : 122 pages
File Size : 41,6 Mb
Release : 1998
Category : Medical
ISBN : 9789241545105
A collection of test procedures for assessing the identity, purity, and content of medicinal plant materials, including determination of pesticide residues, arsenic and heavy metals. Intended to assist national laboratories engaged in drug quality control, the manual responds to the growing use of medicinal plants, the special quality problems they pose, and the corresponding need for international guidance on reliable methods for quality control. Recommended procedures - whether involving visual inspection or the use of thin-layer chromatography for the qualitative determination of impurities - should also prove useful to the pharmaceutical industry and pharmacists working with these materials.
Author : Organización Mundial de la Salud,World Health Organization,WHO
Publisher : World Health Organization
Page : 81 pages
File Size : 43,9 Mb
Release : 2003-12-16
Category : Business & Economics
ISBN : 9789241546270
Medicinal plant materials are supplied through collection from wild populations and cultivation. Under the overall context of quality assurance and control of herbal medicines WHO developed the Guidelines on good agricultural and collection practices (GACP) for medicinal plants providing general technical guidance on obtaining medicinal plant materials of good quality for the sustainable production of herbal products classified as medicines. These guidelines are also related to WHO's work on the protection of medicinal plants aiming promotion of sustainable use and cultivation of medicinal plants. The main objectives of these guidelines are to: (1) contribute to the quality assurance of medicinal plant materials used as the source for herbal medicines to improve the quality safety and efficacy of finished herbal products; (2) guide the formulation of national and/or regional GACP guidelines and GACP monographs for medicinal plants and related standard operating procedures; and (3) encourage and support the sustainable cultivation and collection of medicinal plants of good quality in ways that respect and support the conservation of medicinal plants and the environment in general. These guidelines concern the cultivation and collection of medicinal plants and include certain post-harvest operations. Good agricultural and collection practices for medicinal plants are the first step in quality assurance on which the safety and efficacy of herbal medicinal products directly depend. These practices also play an important role in protection natural resources of medicinal plants for sustainable use.
Author : Daniel Eskinazi
Publisher : Mary Ann Liebert
Page : 244 pages
File Size : 44,6 Mb
Release : 1999
Category : Health & Fitness
ISBN : UOM:39015053496561
Author : Sarah E. Edwards,Ines da Costa Rocha,Elizabeth M. Williamson,Michael Heinrich
Publisher : John Wiley & Sons
Page : 438 pages
File Size : 52,9 Mb
Release : 2015-04-27
Category : Science
ISBN : 9781118543566
Healthcare professionals, including doctors, pharmacists and nurses, are often confronted with patients who use over-the-counter (OTC) herbal medicinal products and food supplements. While taking responsibility for one’s own health and treatment options is encouraged, many patients use these products based on limited (and sometimes inaccurate) information from non-scientific sources, such as the popular press and internet. There is a clear need to offer balanced, well-informed advice to patients, yet a number of studies have shown that, generally, conventionally trained health practitioners consider their knowledge about herbal medicinal products and supplements to be weak. Phytopharmacy fills this knowledge gap, and is intended for use by the busy pharmacist, nurse, or doctor, as well as the ‘expert patient’ and students of pharmacy and herbal medicine. It presents clear, practical and concise monographs on over a hundred popular herbal medicines and plant-based food supplements. Information provided in each monograph includes: • Indications • Summary and appraisal of clinical and pre-clinical evidence • Potential interactions • Contraindications • Possible adverse effects An overview of the current regulatory framework is also outlined, notably the EU Traditional Herbal Medicinal Products Directive. This stipulates that only licensed products or registered traditional herbal medicinal products (THRs), which have assured quality and safety, can now legally be sold OTC. Monographs are included of most of the major herbal ingredients found in THRs, and also some plant-based food supplements, which while not strictly medicines, may also have the potential to exert a physiological effect.
Author : Olavi Pelkonen,Pierre Duez,Pia Maarit Vuorela,Heikki Vuorela
Publisher : Springer
Page : 479 pages
File Size : 46,5 Mb
Release : 2017-03-07
Category : Medical
ISBN : 9783319438061
This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.
Author : Inderbir Singh,Rakesh K. Sindhu,Atul A. Shirkhedkar,Pharkphoom Panichayupakaranant
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 46,8 Mb
Release : 2022-08-23
Category : Medical
ISBN : 9781119818724
Herbal Drug for the Management of Infectious Diseases The book is a comprehensive compilation of herbal drug applications for the treatment and management of infectious diseases and addresses issues related to development, challenges, and future prospects associated with the use of herbal medicine. The use of herbal medicines has evolved in various cultures around the world over many millennia. In many developing Asian and African countries, the use of herbal medicines, as supplied by traditional medicinal practitioners, has always been popular. In the last two to three decades, many people in developed countries have begun to turn to alternative or complementary therapies, including the use of herbal medicines, nutraceuticals, functional foods, and other supplements. This resurgence in interest in plant-derived medicines is partly due to the growing dissatisfaction with allopathic medicines, as well as the perception that plant-derived medicines are natural and therefore pure and without side effects, and the progress in the production of higher quality herbal medicines including some with proven clinical efficacy and safety. Infectious diseases are generally caused by pathogenic microorganisms, like bacteria, viruses, parasites, or fungi, and are a significant cause of morbidity and mortality worldwide. Therefore, the 16 chapters of this book have been intentionally sequenced to cover the therapeutic potential and applications of herbal extracts and phytochemicals for the management of various infectious diseases. Disease pathophysiology, an overview of current medication or treatment, in-vitro and in-vivo evaluations of relevant biological activities of herbal extracts and phytochemicals, mechanisms of action, clinical trials, and novel technologies for the delivery of herbal bioactive compounds as well as patents have also been included. Audience Chemists, pharmaceutical scientists, biologists, herbal/Ayurvedic/medicinal practitioners, as well all those in the medical sciences working on medicinal plants and infectious diseases.
Author : World Health Organization
Publisher : Unknown
Page : 18 pages
File Size : 41,5 Mb
Release : 2004-01-01
Category : Drug monitoring
ISBN : 9241592214
Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.
