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Author : Nandita Maria deSouza,Laure S. Fournier,Daniela Elena Oprea-Lager
Publisher : Frontiers Media SA
Page : 124 pages
File Size : 40,5 Mb
Release : 2022-08-19
Category : Medical
ISBN : 9782889746767
Author : Luis Martí-Bonmatí,Angel Alberich-Bayarri
Publisher : Springer
Page : 316 pages
File Size : 42,8 Mb
Release : 2016-11-03
Category : Medical
ISBN : 9783319435046
This is the first book to cover all aspects of the development of imaging biomarkers and their integration into clinical practice, from the conceptual basis through to the technical aspects that need to be considered in order to ensure that medical imaging can serve as a powerful quantification instrument capable of providing valuable information on organ and tissue properties. The process of imaging biomarker development is considered step by step, covering proof of concept, proof of mechanism, image acquisition, image preparation, imaging biomarker analysis and measurement, detection of measurement biases (proof of principle), proof of efficacy and effectiveness, and reporting of results. Sources of uncertainty in the accuracy and precision of measurements and pearls and pitfalls in gold standards and biological correlation are discussed. In addition, practical use cases are included on imaging biomarker implementation in brain, oncologic, cardiovascular, musculoskeletal, and abdominal diseases. The authors are a multidisciplinary team of expert radiologists and engineers, and the book will be of value to all with an interest in the quantitative imaging of biomarkers in personalized medicine.
Author : Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu
Publisher : Academic Press
Page : 1094 pages
File Size : 52,5 Mb
Release : 2020-11-18
Category : Computers
ISBN : 9780128170588
Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Habib Zaidi
Publisher : Springer Science & Business Media
Page : 593 pages
File Size : 55,8 Mb
Release : 2006-07-11
Category : Science
ISBN : 9780387254449
This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.
Author : Nancy A. Obuchowski,G. Scott Gazelle
Publisher : John Wiley & Sons
Page : 223 pages
File Size : 42,7 Mb
Release : 2016-02-15
Category : Medical
ISBN : 9781118849750
Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference, based on the didactic sessions presented at the annual ‘Clinical Trials Methodology Workshop’ for radiologists, radiation oncologists and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment, and then move into specific topics covering the clinical trials of therapy and clinical research in imaging guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including: an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials.
Author : International Atomic Energy Agency
Publisher : Unknown
Page : 59 pages
File Size : 40,9 Mb
Release : 2014
Category : Medical
ISBN : 9201415109
This publication reviews the current state of the art of image quantification and provides a solid background of tools and methods to medical physicists and other related professionals who are faced with quantification of radionuclide distribution in clinical practice. It describes and analyses the physical effects that degrade image quality and affect the accuracy of quantification, and describes methods to compensate for them in planar, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) images.
Author : Lluís Donoso-Bach,Giles W. L. Boland
Publisher : Springer
Page : 190 pages
File Size : 46,5 Mb
Release : 2018-09-18
Category : Medical
ISBN : 9783319425788
This book provides a roadmap for optimizing quality and safety within radiology practices, whether academic or private and irrespective of their national setting. All aspects of the radiology workflow are addressed, from imaging appropriateness, examination scheduling, and patient preparation through to imaging protocol optimization (including radiation dose management), modality operations, reporting (including structured reporting), and report communication. The book highlights innovative IT tools, including clinical decision support, that drive compliance with national best practice standards and guidelines. The use of big data tools to manage and enhance clinical delivery is addressed. Finally, metrics designed to measure the value that radiology brings to patient care and patient outcomes are introduced. Readers wishing to deepen their understanding of contemporary best practices regarding quality and safety will find this book to be a rich source of practical information.
Author : Ruijiang Li,Lei Xing,Sandy Napel,Daniel L. Rubin
Publisher : CRC Press
Page : 501 pages
File Size : 41,8 Mb
Release : 2019-07-09
Category : Science
ISBN : 9781351208253
Radiomics and Radiogenomics: Technical Basis and Clinical Applications provides a first summary of the overlapping fields of radiomics and radiogenomics, showcasing how they are being used to evaluate disease characteristics and correlate with treatment response and patient prognosis. It explains the fundamental principles, technical bases, and clinical applications with a focus on oncology. The book’s expert authors present computational approaches for extracting imaging features that help to detect and characterize disease tissues for improving diagnosis, prognosis, and evaluation of therapy response. This book is intended for audiences including imaging scientists, medical physicists, as well as medical professionals and specialists such as diagnostic radiologists, radiation oncologists, and medical oncologists. Features Provides a first complete overview of the technical underpinnings and clinical applications of radiomics and radiogenomics Shows how they are improving diagnostic and prognostic decisions with greater efficacy Discusses the image informatics, quantitative imaging, feature extraction, predictive modeling, software tools, and other key areas Covers applications in oncology and beyond, covering all major disease sites in separate chapters Includes an introduction to basic principles and discussion of emerging research directions with a roadmap to clinical translation
Author : Kenji Suzuki,Yisong Chen
Publisher : Springer
Page : 387 pages
File Size : 41,5 Mb
Release : 2018-01-09
Category : Technology & Engineering
ISBN : 9783319688435
This book offers the first comprehensive overview of artificial intelligence (AI) technologies in decision support systems for diagnosis based on medical images, presenting cutting-edge insights from thirteen leading research groups around the world. Medical imaging offers essential information on patients’ medical condition, and clues to causes of their symptoms and diseases. Modern imaging modalities, however, also produce a large number of images that physicians have to accurately interpret. This can lead to an “information overload” for physicians, and can complicate their decision-making. As such, intelligent decision support systems have become a vital element in medical-image-based diagnosis and treatment. Presenting extensive information on this growing field of AI, the book offers a valuable reference guide for professors, students, researchers and professionals who want to learn about the most recent developments and advances in the field.
Author : Nicole Seiberlich,Vikas Gulani,Adrienne Campbell-Washburn,Steven Sourbron,Mariya Ivanova Doneva,Fernando Calamante,Houchun Harry Hu
Publisher : Academic Press
Page : 1092 pages
File Size : 48,5 Mb
Release : 2020-12-10
Category : Computers
ISBN : 9780128170571
Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Andrea S. Doria,George Tomlinson,Joseph Beyene
Publisher : Thieme
Page : 555 pages
File Size : 52,8 Mb
Release : 2018-02-09
Category : Medical
ISBN : 9781604068276
Research Methods in Radiology provides concise, practical insights on how to design clinical and experimental studies in diagnostic imaging. This unique resource encompasses contributions from leaders in academic radiology as well as top epidemiologists, biostatisticians, and librarians with vast multidisciplinary and radiology research experience. The material reflects years of expertise teaching core biostatistics in radiology principles to residents, fellows, radiologists, and epidemiologists. Given the vast amount of published information on research methodology and statistics in radiology, the authors' goal was to write a high-yield review and study tool rather than a comprehensive book. Key topics are succinctly addressed in each chapter, including measurements in radiology; decision analysis in radiology; and systemic reviews, evidence-based imaging, and knowledge translation. Online exercises related to each topic enable residents to prepare for radiology board examinations and research radiologists to apply knowledge to clinical studies. Key Highlights Introductory chapters on analysis of diagnostic tests, linear and logistic regression, meta-analysis, statistical inference, and economic evaluation provide easy-to-follow tutorials Each chapter includes learning objectives, basic concepts, supplementary tables, and ancillary online material Case studies with images, graphs, and tables highlight primary "take home" points Sample size calculations are illustrated for a wide range of research questions Code is included for use in R, free open-source software for statistical analysis This book is an indispensable review of research methodology for radiology students and residents. Practicing clinicians will also benefit from this precisely focused reference tool on clinical and experimental research.
Author : David G. Bragg,Philip Rubin,Hedvig Hricak
Publisher : Saunders
Page : 0 pages
File Size : 54,6 Mb
Release : 2002
Category : Cancer
ISBN : 0721674941
Completely updated to reflect the latest developments in science and technology, the second edition of this reference presents the diagnostic imaging tools essential to the detection, diagnosis, staging, treatment planning, and post-treatment management of cancer in both adults and children. Organized by major organs and body systems, the text offers comprehensive, abundantly illustrated guidance to enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumor imaging. Features 12 brand-new chapters that examine new imaging techniques, molecular imaging, minimally invasive approaches, 3D and conformal treatment planning, interventional techniques in radiation oncology, interventional breast techniques, and more. Emphasizes practical interactions between oncologists and radiologists. Includes expanded coverage of paediatric tumours as well as thorax, gastrointestinal tract, genitourinary, and musculoskeletal cancers. Offers reorganized and increased content on the brain and spinal cord. Nearly 1,400 illustrations enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumour imaging. - Outstanding Features! Presents internationally renowned authors' insights on recent technological breakthroughs in imaging for each anatomical region, and offers their views on future advances in the field. Discusses the latest advances in treatment planning. Devotes four chapters to the critical role of imaging in radiation treatment planning and delivery. Makes reference easy with a body-system organisation.
Author : David A. Clunie
Publisher : PixelMed Publishing
Page : 396 pages
File Size : 42,9 Mb
Release : 2000
Category : Communication in medicine
ISBN : 9780970136909
Author : Ernesto Iadanza
Publisher : Academic Press
Page : 960 pages
File Size : 49,5 Mb
Release : 2019-12-06
Category : Technology & Engineering
ISBN : 9780128134689
Clinical Engineering Handbook, Second Edition, covers modern clinical engineering topics, giving experienced professionals the necessary skills and knowledge for this fast-evolving field. Featuring insights from leading international experts, this book presents traditional practices, such as healthcare technology management, medical device service, and technology application. In addition, readers will find valuable information on the newest research and groundbreaking developments in clinical engineering, such as health technology assessment, disaster preparedness, decision support systems, mobile medicine, and prospects and guidelines on the future of clinical engineering.As the biomedical engineering field expands throughout the world, clinical engineers play an increasingly important role as translators between the medical, engineering and business professions. In addition, they influence procedures and policies at research facilities, universities, and in private and government agencies. This book explores their current and continuing reach and its importance. Presents a definitive, comprehensive, and up-to-date resource on clinical engineering Written by worldwide experts with ties to IFMBE, IUPESM, Global CE Advisory Board, IEEE, ACCE, and more Includes coverage of new topics, such as Health Technology Assessment (HTA), Decision Support Systems (DSS), Mobile Apps, Success Stories in Clinical Engineering, and Human Factors Engineering
Author : P.W. Serruys,D.P. Foley,Pim J. de Feyter
Publisher : Springer Science & Business Media
Page : 754 pages
File Size : 54,6 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9789401583589
Quantitative coronary angiography has become an invaluable tool for the interventional cardiologist, providing objective and reproducible measurements of coronary artery dimensions, which can be used to study progression or regression of coronary atherosclerosis, as well as the immediate and long term effects of percutaneous interventions. Until recently, this powerful imaging technology was confined to a small number of so-called high level institutions. Fortunately, with the development of digital cardiac imaging equipment and adaptation of cine-angiographically based computer software for on-line use in the catheterization room, quantitative coronary angiography is now available to all interventionalists. This book is a timely guide for the impending QCA user, providing practical as well as theoretical and scientific information. A comprehensive evaluation of the clinical usefulness of QCA is covered, from the fundamental principles through experimental validation studies, application to clinical trials of a wide range of pharmacological and interventional therapies in the full spectrum of clinical presentation of coronary disease syndromes, evaluation of the therapeutic efficacy of various new devices for coronary intervention, together with extensive presentation of its physiological, functional and anatomical correlations, by comparison with other intracoronary measurement and imaging techniques. In addition, evolving theories and concepts in the ever topical `restenosis phenomenon' after percutaneous intervention, based on serial QCA studies, are presented and discussed and a potentially unifying methodological approach to further study of this ubiquitous problem is offered. This book, thanks to the collaboration of many experts in the field of intracoronary imaging and measurement, provides stimulating, interesting and practical information, both for the academic scientist and practising clinician.
