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Quantitative Methods for HIV/AIDS Research by Cliburn Chan,Michael G. Hudgens,Shein-Chung Chow Pdf
Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research; the second section focuses on the analysis of laboratory data used for immune monitoring, biomarker discovery and vaccine development; the final section focuses on statistical issues in the mathematical modeling of HIV/AIDS pathogenesis, treatment and epidemiology. This book brings together a broad perspective of new quantitative methods in HIV/AIDS research, contributed by statisticians and mathematicians immersed in HIV research, many of whom are current or previous leaders of CFAR quantitative cores. It is the editors’ hope that the work will inspire more statisticians, mathematicians and computer scientists to collaborate and contribute to the interdisciplinary challenges of understanding and addressing the AIDS pandemic.
Quantitative Evaluation of HIV Prevention Programs by Edward H. Kaplan,Ron Brookmeyer Pdf
How successful are HIV prevention programs? Which HIV prevention programs are most cost effective? Which programs are worth expanding and which should be abandoned altogether? This book addresses the quantitative evaluation of HIV prevention programs, assessing for the first time several different quantitative methods of evaluation. The authors of the book include behavioral scientists, biologists, economists, epidemiologists, health service researchers, operations researchers, policy makers, and statisticians. They present a wide variety of perspectives on the subject, including an overview of HIV prevention programs in developing countries, economic analyses that address questions of cost effectiveness and resource allocation, case studies such as Israel’s ban on Ethiopian blood donors, and descriptions of new methodologies and problems.
Author : Elizabeth Y. Lambert Publisher : Department of Health and Human Services Public Health Servic Page : 276 pages File Size : 50,9 Mb Release : 1995 Category : Medical ISBN : UOM:39015050792871
Techniques in HIV Research by Anna Aldovini,Bruce Walker Pdf
A comprehensive compilation of research techniques necessary for investigating the virology, immunology and molecular biology of HIV-1. Protocols are also provided which represent state of the art approaches to a wide spectrum of HIV related issues.
AIDS Epidemiology by Ron Brookmeyer,Mitchell H. Gail Pdf
AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic. This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project pediatric AIDS incidence -- is not available in any other work.
Preventing AIDS by R Dennis Shelby,Benjamin Bowser,Shiraz Mishra,Cathy Reback Pdf
Learn how to create professional collaboration between HIV/AIDS researchers and community organizations for the benefit of all! This book is designed to help frontline prevention organizations answer two questions that are of utmost importance. First, how effective are their services; and second, can their work be improved? The absence of rigorous evaluation is a barrier to stable funding for community organizations, and the strategies in Preventing AIDS: Community-Science Collaborations can help overcome that barrier. The book is a guide to successful cooperative efforts between researchers and community-based organizations. The information it presents will help community-based programs acquire detailed, timely information on program effectiveness and outcomes. It also provides researchers with methods for accessing hard-to-reach or hidden HIV high-risk groups. Handy tables and figures make important data easy to access and understand. In Preventing AIDS: Community-Science Collaborations, you’ll learn about the difficult but critically important collaboration between community organizations who do frontline prevention work and university scientists who evaluate the effectiveness of that work. The book describes the community-researcher equal partner collaboration (CREPC) model for community-based collaborative research. In addition, it examines six unique efforts to prevent the spread of AIDS among high-risk populations, such as prostitutes, injection drug users, impoverished pregnant women, migrant workers, transgendered persons, and prison inmates. The case studies in Preventing AIDS: Community-Science Collaborations describe the frustrations of outreach workers and counselors who suddenly must help design a survey they fear will be intrusive, and the parallel problems faced by scientists who are told that their traditional measures mean little to outreach workers. Preventing AIDS: Community-Science Collaborations presents funders’ perspectives on collaborative AIDS research and examines the collaborative and funding aspects of: the CAL-PEP prevention programs for drug injectors and sex workers efforts to promote HIV prevention for migrant farm workers and evaluate those efforts’ effectiveness the ongoing collaboration between The Center for AIDS Prevention Studies (University of California, San Francisco), Centerforce (a statewide nonprofit agency providing services and advocacy to prisoners and their families), and San Quentin State Prison the effort of the Los Angeles County HIV Epidemiology Program and three community-based organizations, which collaborate to provide culturally appropriate outreach and HIV education/prevention services to transgendered individuals of various ethnic origins San Francisco’s PHREDA project and the way its creators collaborated to better understand and serve high-risk women The U-Find-Out (UFO) Study, funded by the Universitywide AIDS Research Program of the State of California
Deterministic and Stochastic Models of AIDS Epidemics and HIV Infections with Intervention by Wai-Yuan Tan,Hulin Wu Pdf
With contributions from an international team of leading researchers, the book pulls together updated research results in the area of HIV/AIDS modeling to provide readers with the latest information in the field. Topics covered include: AIDS epidemic models; vaccine models; models for HIV/cell dynamics and interactions; cellular kinetics; viral dynamics with antiviral treatments; modeling of drug resistance and quasispecies. Extensive deterministic models, statistical models, stochastic models and state space models on treating AIDS patients with anti-retroviral drugs are provided, as well as an in-depth discussion of these models. The book also contains updated reviews on mathematical models for assessing effects of AIDS vaccines, statistical methods for analyzing clinical trial data on AIDS vaccines, and overviews of models and statistical methods for assessing drug resistance of HIV to anti-retroviral drugs. Some important statistical methods specific to the intervention and prevention of HIV epidemic are also discussed. This will be a useful reference source for graduate students and researchers in biomathematics and biostatistics, as well as for HIV/AIDS epidemiologists and clinical investigators learning quantitative methods to study AIDS epidemics and HIV infection. Contents:Mathematical Models for HIV Transmission Among Injecting Drug Users (V Capasso & D Morale)A Class of Methods for HIV Contact Tracing in Cuba: Implications for Intervention and Treatment (Y-H Hsieh et al.)Dynamical Models for the Course of an HIV Infection (C Kamp)Identifiability of HIV/AIDS Models (A M Jeffrey & X Xia)A Branching Process Model of Drug Resistant HIV (H Zhou & K S Dorman)Design of Population Studies of HIV Dynamics (C Han & K Chaloner)Statistical Estimation, Inference and Hypothesis Testing of Parameters in Ordinary Differential Equations Models of HIV Dynamics (S Holte)and other papers Readership: Upper-level undergraduates, graduate students, biomathematical and biostatistical researchers, HIV/AIDS epidemiologists and researchers, AIDS clinical investigators. Keywords:AIDS Epidemics;AIDS Vaccines;Antiviral Treatments;Cell Kinetics;HIV Dynamics;Viral ResistanceKey Features:Only book that provides deterministic and stochastic models of AIDS vaccines and statistical methods for analyzing clinical trial data on AIDS vaccinesOnly book on extensive, deterministic models, statistical models, stochastic models and state space models and statistical methods for HIV epidemic involving IV drug usage and HIV epidemic in homosexual populationsProvides most recent biological insights into HIV pathogenesis and HIV kinetics at the cellular level, and illustrates how to build up mathematical models based on these biological insightsOnly publication that provides in-depth analysis of HAART treatment protocols and discusses possible improvements to the HAART protocol. The book also provides connection between pharmacokinetics with treatment in HIV-infected individuals
National Institutes of Health (U.S.). Office of AIDS Research
Author : National Institutes of Health (U.S.). Office of AIDS Research Publisher : Unknown Page : 296 pages File Size : 41,9 Mb Release : 2002 Category : AIDS (Disease) ISBN : IND:30000104163245
National Research Council,Division of Behavioral and Social Sciences and Education,Commission on Behavioral and Social Sciences and Education,Panel on Data and Research Priorities for Arresting AIDS in Sub-Saharan Africa
Author : National Research Council,Division of Behavioral and Social Sciences and Education,Commission on Behavioral and Social Sciences and Education,Panel on Data and Research Priorities for Arresting AIDS in Sub-Saharan Africa Publisher : National Academies Press Page : 369 pages File Size : 40,7 Mb Release : 1996-03-28 Category : Medical ISBN : 9780309090186
Preventing and Mitigating AIDS in Sub-Saharan Africa by National Research Council,Division of Behavioral and Social Sciences and Education,Commission on Behavioral and Social Sciences and Education,Panel on Data and Research Priorities for Arresting AIDS in Sub-Saharan Africa Pdf
The AIDS epidemic in Sub-Saharan Africa continues to affect all facets of life throughout the subcontinent. Deaths related to AIDS have driven down the life expectancy rate of residents in Zambia, Kenya, and Uganda with far-reaching implications. This book details the current state of the AIDS epidemic in Africa and what is known about the behaviors that contribute to the transmission of the HIV infection. It lays out what research is needed and what is necessary to design more effective prevention programs.
Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee on HIV Prevention Strategies in the United States
Author : Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee on HIV Prevention Strategies in the United States Publisher : National Academies Press Page : 253 pages File Size : 41,9 Mb Release : 2001-02-02 Category : Medical ISBN : 9780309171557
No Time to Lose by Institute of Medicine,Division of Health Promotion and Disease Prevention,Committee on HIV Prevention Strategies in the United States Pdf
The United States has spent two productive decades implementing a variety of prevention programs. While these efforts have slowed the rate of infection, challenges remain. The United States must refocus its efforts to contain the spread of HIV and AIDS in a way that would prevent as many new HIV infections as possible. No Time to Lose presents the Institute of Medicine's framework for a national prevention strategy.
The HIV/AIDS epidemic has presented considerable challenges to social researchers to provide detailed and accurate information about "sensitive" behaviour amongst "hidden" populations, to develop theories to explain and predict how and why behaviour changes; and to carry out assessments of knowledge, attitudes, practices and the effectiveness of health education interventions in shaping these. This volume draws together examples of innovative research which has been conducted in the field of HIV/AIDS and describes the relevance of these methods for research in health behaviour more generally. The chapters are drawn from the work of 12 research groups who, in response to the challenge of HIV/AIDS research, have developed the tools of social research to new degrees of sophistication or put them to use in novel and imaginative ways. While the emphasis in this book is on the methods the researchers have developed, it is in the substantive findings of their studies, and their contribution to our understanding of the epidemic, that the methods have proved their worth.; The AIDS epidemic has "changed the rule" for social research on health and illness. The urgency surrounding the epidemic has given rise to an openness to different disciplines and new approaches within the research community. For example, questions of the reliability and validity of accounts of "private" behaviour have been given new consideration, as have the theoretical underpinnings of research which looks at vulnerable or "disadvantaged" groups within society. The developments described in this volume represent the way social science has been taken forward by researchers who have confronted the challenges posed by research on the social dimensions of HIV/AIDS.
Author : Richard A. Crosby,Ralph J. DiClemente Publisher : Oxford University Press Page : 384 pages File Size : 54,6 Mb Release : 2018-10-26 Category : Medical ISBN : 9780190930806
Structural Interventions for HIV Prevention by Richard A. Crosby,Ralph J. DiClemente Pdf
A COMPREHENSIVE NEW REFERENCE WORK ON STRUCTURAL APPROACHES TO PREVENTING HIV Structural interventions -- changes to environment aimed at influencing health behaviors -- are the most universal and cost-effective tool in preventing new incidences of HIV. They are not easy to get right, however. Structural Interventions for HIV Prevention offers an authoritative reference for both understanding these programs and instituting them to greatest effect. Whether through changes to policy, environment, social/community norms, or a combination of each, this volume offers actionable and attainable blueprints to creating and evaluating programs in any setting or country. It is an essential resource for researchers and practitioners in the continuing fights against HIV.
