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Quantitative risk assessments cannot eliminate risk, nor can they resolve trade-offs. They can, however, guide principled risk management and reduction - if the quality of assessment is high and decision makers understand how to use it. This book builds a unifying scientific framework for discussing and evaluating the quality of risk assessments and whether they are fit for purpose. Uncertainty is a central topic. In practice, uncertainties about inputs are rarely reflected in assessments, with the result that many safety measures are considered unjustified. Other topics include the meaning of a probability, the use of probability models, the use of Bayesian ideas and techniques, and the use of risk assessment in a practical decision-making context. Written for professionals, as well as graduate students and researchers, the book assumes basic probability, statistics and risk assessment methods. Examples make concepts concrete, and three extended case studies show the scientific framework in action.
Risk Analysis concerns itself with the quantification of risk, the modeling of identified risks and how to make decisions from those models. Quantitative risk analysis (QRA) using Monte Carlo simulation offers a powerful and precise method for dealing with the uncertainty and variability of a problem. By providing the building blocks the author guides the reader through the necessary steps to produce an accurate risk analysis model and offers general and specific techniques to cope with most modeling problems. A wide range of solved problems is used to illustrate these techniques and how they can be used together to solve otherwise complex problems.
Author : Louis Anthony Cox Jr. Publisher : Springer Science & Business Media Page : 363 pages File Size : 53,8 Mb Release : 2006-03-17 Category : Medical ISBN : 9780387261188
Quantitative Health Risk Analysis Methods by Louis Anthony Cox Jr. Pdf
This book grew out of an effort to salvage a potentially useful idea for greatly simplifying traditional quantitative risk assessments of the human health consequences of using antibiotics in food animals. In 2001, the United States FDA’s Center for Veterinary Medicine (CVM) (FDA-CVM, 2001) published a risk assessment model for potential adverse human health consequences of using a certain class of antibiotics, fluoroquinolones, to treat flocks of chickens with fatal respiratory disease caused by infectious bacteria. CVM’s concern was that fluoroquinolones are also used in human medicine, raising the possibility that fluoroquinolone-resistant strains of bacteria selected by use of fluoroquinolones in chickens might infect humans and then prove resistant to treatment with human medicines in the same class of antibiotics, such as ciprofloxacin. As a foundation for its risk assessment model, CVM proposed a dramatically simple approach that skipped many of the steps in traditional risk assessment. The basic idea was to assume that human health risks were directly proportional to some suitably defined exposure metric. In symbols: Risk = K × Exposure, where “Exposure” would be defined in terms of a metric such as total production of chicken contaminated with fluoroquinolone-resistant bacteria that might cause human illnesses, and “Risk” would describe the expected number of cases per year of human illness due to fluoroquinolone-resistant bacterial infections caused by chicken and treated with fluoroquinolones.
Encyclopedia of Quantitative Risk Analysis and Assessment by Anonim Pdf
Leading the way in this field, the Encyclopedia of Quantitative Risk Analysis and Assessment is the first publication to offer a modern, comprehensive and in-depth resource to the huge variety of disciplines involved. A truly international work, its coverage ranges across risk issues pertinent to life scientists, engineers, policy makers, healthcare professionals, the finance industry, the military and practising statisticians. Drawing on the expertise of world-renowned authors and editors in this field this title provides up-to-date material on drug safety, investment theory, public policy applications, transportation safety, public perception of risk, epidemiological risk, national defence and security, critical infrastructure, and program management. This major publication is easily accessible for all those involved in the field of risk assessment and analysis. For ease-of-use it is available in print and online.
Guidelines for Chemical Process Quantitative Risk Analysis by CCPS (Center for Chemical Process Safety) Pdf
Chemical process quantitative risk analysis (CPQRA) as applied to the CPI was first fully described in the first edition of this CCPS Guidelines book. This second edition is packed with information reflecting advances in this evolving methodology, and includes worked examples on a CD-ROM. CPQRA is used to identify incident scenarios and evaluate their risk by defining the probability of failure, the various consequences and the potential impact of those consequences. It is an invaluable methodology to evaluate these when qualitative analysis cannot provide adequate understanding and when more information is needed for risk management. This technique provides a means to evaluate acute hazards and alternative risk reduction strategies, and identify areas for cost-effective risk reduction. There are no simple answers when complex issues are concerned, but CPQRA2 offers a cogent, well-illustrated guide to applying these risk-analysis techniques, particularly to risk control studies. Special Details: Includes CD-ROM with example problems worked using Excel and Quattro Pro. For use with Windows 95, 98, and NT.
Quantitative Risk Assessment (QRA) for Natural Hazards by Nasim Uddin,Alfredo Hua-Sing Ang Pdf
CDRM 5 explains the the practical aspects of using quantitative risk assessment (QRA) to develop optimal engineering designs that mitigate the effects of natural hazards, especially on civil infrastructure.
Quantitative Risk Assessment for Environmental and Occupational Health by William H. Hallenbeck Pdf
Many individuals and groups need a usable treatment of the methodology required to assess the human health risks caused by toxicant exposure. This need is shared by industrial hygienists, environmental, occupational and public health professionals, toxicologists, epidemiologists, labor unions, attorneys, regulatory officials, and manufacturers and users of chemicals. The reader needs only a basic knowledge of biology adn algebra in order to utilize the methodology presented. In addition, a basic knowledge of toxicology, epidemiology, and statistics is derisrable for a full understanding of some aspects of risk assessment. Sophisticated computer programs are not required. All the computations can be carried out with a pocked calculator.
Quantitative Risk Assessment in Fire Safety by Ganapathy Ramachandran,David Charters Pdf
Fire safety regulations in many countries require Fire Risk Assessment to be carried out for buildings such as workplaces and houses in multiple occupation. This duty is imposed on a "Responsible Person" and also on any other persons having control of buildings in compliance with the requirements specified in the regulations. Although regulations only require a qualitative assessment of fire risk, a quantitative assessment is an essential first step for performing cost-benefit analysis of alternative fire strategies to comply with the regulations and selecting the most cost-effective strategy. To facilitate this assessment, various qualitative, semi-quantitative and quantitative techniques of fire risk assessment, already developed, are critically reviewed in this book and some improvements are suggested. This book is intended to be an expanded version of Part 7: Probabilistic risk assessment, 2003, a Published Document (PD) to British Standard BS 7974: 2001 on the Application of Fire Safety Engineering Principles to the Design of Buildings. Ganapathy Ramachandran and David Charters were co-authors of PD 7974 Part 7. Quantitative Risk Assessment in Fire Safety is essential reading for consultants, academics, fire safety engineers, fire officers, building control officers and students in fire safety engineering. It also provides useful tools for fire protection economists and risk management professionals, including those involved in fire insurance underwriting.
Handbook of Safety Principles by Niklas Möller,Sven Ove Hansson,Jan-Erik Holmberg,Carl Rollenhagen Pdf
Presents recent breakthroughs in the theory, methods, and applications of safety and risk analysis for safety engineers, risk analysts, and policy makers Safety principles are paramount to addressing structured handling of safety concerns in all technological systems. This handbook captures and discusses the multitude of safety principles in a practical and applicable manner. It is organized by five overarching categories of safety principles: Safety Reserves; Information and Control; Demonstrability; Optimization; and Organizational Principles and Practices. With a focus on the structured treatment of a large number of safety principles relevant to all related fields, each chapter defines the principle in question and discusses its application as well as how it relates to other principles and terms. This treatment includes the history, the underlying theory, and the limitations and criticism of the principle. Several chapters also problematize and critically discuss the very concept of a safety principle. The book treats issues such as: What are safety principles and what roles do they have? What kinds of safety principles are there? When, if ever, should rules and principles be disobeyed? How do safety principles relate to the law; what is the status of principles in different domains? The book also features: • Insights from leading international experts on safety and reliability • Real-world applications and case studies including systems usability, verification and validation, human reliability, and safety barriers • Different taxonomies for how safety principles are categorized • Breakthroughs in safety and risk science that can significantly change, improve, and inform important practical decisions • A structured treatment of safety principles relevant to numerous disciplines and application areas in industry and other sectors of society • Comprehensive and practical coverage of the multitude of safety principles including maintenance optimization, substitution, safety automation, risk communication, precautionary approaches, non-quantitative safety analysis, safety culture, and many others The Handbook of Safety Principles is an ideal reference and resource for professionals engaged in risk and safety analysis and research. This book is also appropriate as a graduate and PhD-level textbook for courses in risk and safety analysis, reliability, safety engineering, and risk management offered within mathematics, operations research, and engineering departments. NIKLAS MÖLLER, PhD, is Associate Professor at the Royal Institute of Technology in Sweden. The author of approximately 20 international journal articles, Dr. Möller's research interests include the philosophy of risk, metaethics, philosophy of science, and epistemology. SVEN OVE HANSSON, PhD, is Professor of Philosophy at the Royal Institute of Technology. He has authored over 300 articles in international journals and is a member of the Royal Swedish Academy of Engineering Sciences. Dr. Hansson is also a Topical Editor for the Wiley Encyclopedia of Operations Research and Management Science. JAN-ERIK HOLMBERG, PhD, is Senior Consultant at Risk Pilot AB and Adjunct Professor of Probabilistic Riskand Safety Analysis at the Royal Institute of Technology. Dr. Holmberg received his PhD in Applied Mathematics from Helsinki University of Technology in 1997. CARL ROLLENHAGEN, PhD, is Adjunct Professor of Risk and Safety at the Royal Institute of Technology. Dr. Rollenhagen has performed extensive research in the field of human factors and MTO (Man, Technology, and Organization) with a specific emphasis on safety culture and climate, event investigation methods, and organizational safety assessment.
Author : Charles N. Haas,Joan B. Rose,Charles P. Gerba Publisher : John Wiley & Sons Page : 440 pages File Size : 50,5 Mb Release : 2014-06-09 Category : Technology & Engineering ISBN : 9781118910023
Quantitative Microbial Risk Assessment by Charles N. Haas,Joan B. Rose,Charles P. Gerba Pdf
Provides the latest QMRA methodologies to determine infection riskcause by either accidental microbial infections or deliberateinfections caused by terrorism • Reviews the latest methodologies to quantify at everystep of the microbial exposure pathways, from the first release ofa pathogen to the actual human infection • Provides techniques on how to gatherinformation, on how each microorganism moves through theenvironment, how to determine their survival rates on variousmedia, and how people are exposed to the microorganism • Explains how QMRA can be used as a tool to measure theimpact of interventions and identify the best policies andpractices to protect public health and safety • Includes new information on genetic methods • Techniques use to develop risk models for drinkingwater, groundwater, recreational water, food and pathogens in theindoor environment
Quantitative Risk Management and Decision Making in Construction by Amarjit Singh Pdf
Singh introduces valuable techniques for weighing and evaluating alternatives in decision making with a focus on risk analysis for identifying, quantifying, and mitigating risks associated with construction projects.
National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Commission on Life Sciences,Committee on Risk Assessment of Hazardous Air Pollutants
Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Commission on Life Sciences,Committee on Risk Assessment of Hazardous Air Pollutants Publisher : National Academies Press Page : 668 pages File Size : 55,9 Mb Release : 1994-01-01 Category : Science ISBN : 9780309048941
Science and Judgment in Risk Assessment by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Commission on Life Sciences,Committee on Risk Assessment of Hazardous Air Pollutants Pdf
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Guidelines for Developing Quantitative Safety Risk Criteria by CCPS (Center for Chemical Process Safety) Pdf
Written by a committee of safety professionals, this book creates a foundation document for the development and application of risk tolerance criteria Helps safety managers evaluate the frequency, severity and consequence of human injury Includes examples of risk tolerance criteria used by NASA, Earthquake Response teams and the International Maritime Organization, amongst others Helps achieve consistency in risk-based decision-making Reduces potential liabilities in the use of quantitative risk tolerance criteria through reference to an industry guidance document
