Radiobiology In Radiotherapy

Author : Norman M. Bleehen
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 53,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781447116035

Get Book

Radiobiology in Radiotherapy by Norman M. Bleehen Pdf

The ninth annual multidisciplinary symposium on clinical oncology organized by the Royal College of Radiologists was jointly arranged with the International Society for Radiation Oncology. It was held in London in February 1987 and discussed the biological and clinical basis of the effects of radiotherapy. Wherever possible lectures by an experimental scientist were paired with those of a clinical scientist in order to emphasize clinical relevance. It is hoped that this has resulted in a widely balanced view of the subject. The volume presents an updated version of these subjects based on those talks. After surgery, radiotherapy is the main treatment used in the management of patients with cancer. Its empirical success when first introduced is now backed up by a wealth of laboratory, clinical and experimental experience. New techniques for adminis tering the conventional X-ray therapy have been supplemented by methods which can be used to modify the radiation response. These include changes in dose rate or fractionation, and combined modality treatments including sensitization by drugs or heat. Other types of radiation, such as neutrons and other particles, are also now available which have enhanced physical and biological advantages.

Author : Eric J. Hall,Amato J. Giaccia
Publisher : Lippincott Williams & Wilkins
Page : 624 pages
File Size : 43,9 Mb
Release : 2018-04-16
Category : Medical
ISBN : 9781496395139

Get Book

Radiobiology for the Radiologist by Eric J. Hall,Amato J. Giaccia Pdf

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Considered the “gold standard” in the field for over 45 years, Radiobiology for the Radiologist combines traditional and molecular radiation biology principles and appeals to students, residents, and veteran clinical practitioners. This edition continues the two-part format of previous editions and features brand-new chapters, thoroughly updated content, and hundreds of figures that provide a visual context to the information in each chapter.

Author : Juan A. Del Regato
Publisher : Unknown
Page : 308 pages
File Size : 54,7 Mb
Release : 1967
Category : Cancer
ISBN : MINN:31951D02987108H

Get Book

Conference on Radiobiology and Radiotherapy by Juan A. Del Regato Pdf

Author : Maurice Tubiana
Publisher : CRC Press
Page : 269 pages
File Size : 53,8 Mb
Release : 2005-10-10
Category : Medical
ISBN : 9780203983669

Get Book

Introduction To Radiobiology by Maurice Tubiana Pdf

This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.

Author : Michael C. Joiner,Albert J. van der Kogel
Publisher : CRC Press
Page : 766 pages
File Size : 50,7 Mb
Release : 2018-08-28
Category : Medical
ISBN : 9780429955396

Get Book

Basic Clinical Radiobiology by Michael C. Joiner,Albert J. van der Kogel Pdf

Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.

Author : Jennifer Yu, MD, PhD,Mohamed Abazeed, MD, PhD
Publisher : Springer Publishing Company
Page : 520 pages
File Size : 48,9 Mb
Release : 2016-11-03
Category : Medical
ISBN : 9781617052910

Get Book

Radiobiology Self-Assessment Guide by Jennifer Yu, MD, PhD,Mohamed Abazeed, MD, PhD Pdf

Radiobiology Self-Assessment Guide--a companion to the Radiation Oncology Self-Assessment Guide and Physics in Radiation Oncology Self-Assessment Guide--is a comprehensive review for practitioners of radiation oncology looking to enhance their knowledge of radiobiology. It covers in depth the principles of radiobiology as applied to radiation oncology along with their clinical applications. To foster retention of key concepts and data, the resource utilizes a user-friendly "flash card" question and answer format with over 700 questions. The questions are supported by detailed answers and rationales along with reference citations for source information. The guide is comprised of 29 chapters and cover topics commonly found on the radiation and cancer biology portion of the radiation oncology board examination. Aspects of basic radiobiology covered include fundamentals such as cell cycle, cell survival curves and interactions of radiation with matter, and acute and long-term sequelae of radiation. Modern concepts such as immunotherapy, radiogenomics, and normal and cancer stem cells are also included. Focused and authoritative, this must-have review provides the expertise of faculty from the Department of Radiation Oncology at the Cleveland Clinic Taussig Cancer Institute and Lerner Research Institute. Key Features: Provides a comprehensive study guide for the Radiation and Cancer Biology portion to the Radiation Oncology Board Exam Includes more than 700 questions with detailed answers and rationales on flip pages for easy, flash card-like review Includes essential review of cancer biology concepts such as immunotherapy, stem cells, gene therapy, chemotherapy and targeted agents Content provided by a vast array of contributors, including attending radiation oncology physicians, physicists, and radiation oncology residents

Author : J. Dutreix,A. Wambersie
Publisher : CRC Press
Page : 618 pages
File Size : 52,7 Mb
Release : 1990-09-01
Category : Medical
ISBN : 0850667453

Get Book

Introduction to Radiobiology by J. Dutreix,A. Wambersie Pdf

This textbook covers all aspects of radiation, radiotherapy and their effects. The book, initially published in France, has been updated and expanded in this English version. It includes a thorough discussion of recent advances, such as a better understanding of the molecular basis of cellular effects and cell radiosensitivity.There is a study of the mechanmism by which dose and overall duration of radiotherapy can introoduce differential effects between normal and neoplastic tissues and recent data on radiocarcinogenesis in man and experimental animals is provided.

Author : J. Donald Chapman,Alan E. Nahum
Publisher : CRC Press
Page : 190 pages
File Size : 41,5 Mb
Release : 2016-04-21
Category : Science
ISBN : 9781439862605

Get Book

Radiotherapy Treatment Planning by J. Donald Chapman,Alan E. Nahum Pdf

Understand Quantitative Radiobiology from a Radiation Biophysics Perspective In the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and offers appropriate LQ parameters for modeling tumor and normal tissue responses. Explore the Latest Cell Killing Numbers for Defining Iso-Effective Cancer Treatments The book compiles radiation mechanism information from biophysical publications of the past 50 years, addressing how ionizing radiation produces the killing of stem cells in human tumors. It presents several physical and chemical parameters that can modulate the radiation response of clonogenic cells in tumors. The authors describe the use of the LQ model in basic radiation mechanism studies with cells of relatively homogeneous radiation response and then extend the model to the fitting of survival data generated with heterogeneous cell populations (tumors). They briefly discuss how to use the LQ model for predicting tumor (local) control probability (TCP) and normal tissue complication probability (NTCP). The book also examines potential molecular targets related to alpha- and beta-inactivation and gives suggestions for further molecular characterizations of these two independent processes. Develop Efficacious, Patient-Friendly Treatments at Reduced Costs Focusing on quantitative radiobiology in LQ formulation, this book assists medical physicists and radiation oncologists in identifying improved cancer treatments. It also encourages investigators to translate potentially improved radiotherapy schedules based on TCP and NTCP modeling into actual patient benefit.

Author : Eric J. Hall
Publisher : Unknown
Page : 328 pages
File Size : 51,6 Mb
Release : 1973
Category : Medical
ISBN : UOM:39015003206110

Get Book

Radiobiology for the Radiologist by Eric J. Hall Pdf

The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review. The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.

Author : H. Awwad
Publisher : Springer Science & Business Media
Page : 677 pages
File Size : 40,6 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9789401578653

Get Book

Radiation Oncology: Radiobiological and Physiological Perspectives by H. Awwad Pdf

During the past four decades knowledge about biological effects of ionizing radiations on mammalian cells, normal tissues and tumours has increased enormously and has enabled radiotherapists to obtain a better insight into the advantages and disadvantages of cancer treatments with modified regimens of irradiations and combinations with chemotherapeutic agents. Even for the older scientists and clinicians who have wit nessed all these developments and have contributed to the vast amount of information, it is difficult to integrate this knowledge and to apply it in their daily work. For younger workers it is often difficult to select the important main concepts and results from the overwhelming number of publications. It is evident that a book which provides an integrated view of basic and applied radiation oncology can be of great value to students, scientists and, most importantly, to clinicians who can devote only part of their time to the task of understanding the radiobiological background of their application of radiation in cancer treatment. This book "Radiation Oncology" is written by a radiotherapist who has for a long time participated in the integration of basic knowledge and clinical experience. He has selected radiobiological information which is considered important to radiotherapy and in the description and interpretation of normal tissue tolerance and tumour eradication probability, he illustrates how basic knowledge can be applied clinically.

Author : Susan B Klein,Marc S Mendonca
Publisher : World Scientific
Page : 399 pages
File Size : 43,8 Mb
Release : 2023-01-04
Category : Medical
ISBN : 9789811257674

Get Book

Fundamentals Of Radiation Biology by Susan B Klein,Marc S Mendonca Pdf

Fundamentals of Radiation Biology presents a contemporary, comprehensive review of the interactions between ionizing radiations and biological materials, tracking the consequences to three inevitable endpoints: cell restitution, cell death, or cell transformation.The introductory narrative is followed by examination of larger scale phenomena including tissue responses to radiation injury, organ failure modes, and resultant human illness including cancer. Ultimately, Fundamentals of Radiation Biology considers circumstantial radiation incidents impacting biological systems including radiological terrorism and radiation pollution remediation. Chapters presenting an overview of carcinogenesis and radiation therapy techniques based in radiobiology discuss two significant expansions central to the concerns of the text.This book takes an unprecedented narrative approach to radiobiology; each chapter expands on the fundamentals surveyed previously to lead the reader steadily to a panorama of radiation biocomplexity. No biological event happens in isolation. Actions evoke reactions that alter structures and cause living systems to adapt. It also examines the components constituting mammalian radiation response machinery and correlates them with resultant physiological behaviors.

Author : Michael C. Joiner,Albert van der Kogel
Publisher : CRC Press
Page : 392 pages
File Size : 53,5 Mb
Release : 2009-03-27
Category : Medical
ISBN : 9780340929667

Get Book

Basic Clinical Radiobiology Fourth Edition by Michael C. Joiner,Albert van der Kogel Pdf

This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.

Author : Loredana G. Marcu,Iuliana Toma-Dasu,Alexandru Dasu,Claes Mercke
Publisher : CRC Press
Page : 220 pages
File Size : 46,8 Mb
Release : 2018-05-15
Category : Science
ISBN : 9781351001991

Get Book

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer by Loredana G. Marcu,Iuliana Toma-Dasu,Alexandru Dasu,Claes Mercke Pdf

Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. Features: Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics Applies content by relating all radiobiological characteristics to their respective clinical implications Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

Author : David S. Chang,Foster D. Lasley,Indra J. Das,Marc S. Mendonca,Joseph R. Dynlacht
Publisher : Springer
Page : 347 pages
File Size : 53,6 Mb
Release : 2014-09-19
Category : Medical
ISBN : 9783319068411

Get Book

Basic Radiotherapy Physics and Biology by David S. Chang,Foster D. Lasley,Indra J. Das,Marc S. Mendonca,Joseph R. Dynlacht Pdf

This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. Basic Radiotherapy Physics and Biology is a valuable reference for students and prospective students in every discipline of radiation oncology.

Author : George Gordon Steel,Gerald E. Adams,Michael J. Peckham
Publisher : Elsevier Publishing Company
Page : 360 pages
File Size : 53,9 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015006000155

Get Book

The Biological Basis of Radiotherapy by George Gordon Steel,Gerald E. Adams,Michael J. Peckham Pdf