Recent Advances In Pharmacology And Physiology Of Cannabinoids

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Recent Advances in Cannabinoid Physiology and Pathology

Anna N. Bukiya
Recent Advances in Cannabinoid Physiology and Pathology Book PDF

Author : Anna N. Bukiya
Publisher : Springer
Page : 167 pages
File Size : 53,7 Mb
Release : 2019-07-22
Category : Science
ISBN : 9783030217372

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Recent Advances in Cannabinoid Physiology and Pathology by Anna N. Bukiya Pdf

The cannabinoid system plays a central role in a wide variety of physiological functions that touch upon cardiovascular, gastrointestinal, immune, and nervous systems. Cannabinoids also play a central role in developmental physiology, management of pain, and shaping of human behaviour. Recent movements towards legalization of marijuana use have bolstered scientific interest in the cannabinoid field and led to research efforts that would unveil multi-faceted effects and mechanisms of cannabinoid presence in different organs and at various stages of development. This book summarizes the recent advances in the field of cannabinoid research at multiple levels of resolution. It spans from systemic effects of cannabinoids on development, physiological function, and prevalent pathophysiological conditions to mechanisms that govern cannabinoid interaction with their relevant protein targets at atomic resolution. This book will be of interest to a specialized audience in the fields of biochemistry, pharmacology and developmental biology but alsoto a wider readership with interest in general physiology and cannabinoid signalling in biological systems.

Recent Advances in Cannabinoid Research

Willard James Costain,Robert Brad Laprairie
Recent Advances in Cannabinoid Research Book PDF

Author : Willard James Costain,Robert Brad Laprairie
Publisher : BoD – Books on Demand
Page : 232 pages
File Size : 48,5 Mb
Release : 2019-05-10
Category : Medical
ISBN : 9781838801519

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Recent Advances in Cannabinoid Research by Willard James Costain,Robert Brad Laprairie Pdf

Scientific interest in cannabinoid research is currently experiencing a significant increase because of changing attitudes toward Cannabis and the evolving awareness of its pharmaceutical benefits. Coincidently, numerous jurisdictions are moving toward legalizing Cannabis and Cannabis-derived products, which reflects a larger global movement to understand Cannabis and its bioactive chemicals for their potential biomedical uses, harms, and economic value. Research activities are surging to fill important knowledge gaps in the field of cannabinoids as they continue to be identified. The purpose of this book is to summarize some leading areas of research in the cannabinoid field where knowledge gaps are actively being addressed. The research described herein spans basic biological and clinical research.

Recent Advances in the Science of Cannabis

Robert M. Strongin,Jiries Meehan-Atrash,Monica Vialpando
Recent Advances in the Science of Cannabis Book PDF

Author : Robert M. Strongin,Jiries Meehan-Atrash,Monica Vialpando
Publisher : Unknown
Page : 0 pages
File Size : 48,8 Mb
Release : 2024-01-29
Category : Cannabinoids
ISBN : 1032119594

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Recent Advances in the Science of Cannabis by Robert M. Strongin,Jiries Meehan-Atrash,Monica Vialpando Pdf

This unique book covers topics in cultivation and secondary metabolites, aroma and chemotypes, cannabinoid structures, physiology and pharmacology, as well as the development of unique topical products. Given the popularity of smoking and vaporizing cannabis, the chemistry of vaping cannabinoid and terpene concentrates is also presented.

Cannabinoids as Therapeutics

Raphael Mechoulam
Cannabinoids as Therapeutics Book PDF

Author : Raphael Mechoulam
Publisher : Springer Science & Business Media
Page : 278 pages
File Size : 52,5 Mb
Release : 2006-03-30
Category : Medical
ISBN : 9783764373580

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Cannabinoids as Therapeutics by Raphael Mechoulam Pdf

Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body - in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases. The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis. The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.

Cannabinoid Pharmacology

Anonim
Cannabinoid Pharmacology Book PDF

Author : Anonim
Publisher : Academic Press
Page : 492 pages
File Size : 54,9 Mb
Release : 2017-08-18
Category : Medical
ISBN : 9780128112335

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Cannabinoid Pharmacology by Anonim Pdf

Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered. Presents reviews of recent breakthroughs in the cannabinoid system Features chapters from the best authors in the field Provides an essential resource for scientists, advanced undergraduate students through to established faculty members

Endocannabinoids

Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
Endocannabinoids Book PDF

Author : Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
Publisher : CRC Press
Page : 592 pages
File Size : 45,8 Mb
Release : 2005-11-01
Category : Science
ISBN : 1420023640

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Endocannabinoids by Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo Pdf

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.

Marijuana/Cannabinoids

Laura L. Murphy,Andrzej Bartke
Marijuana Cannabinoids Book PDF

Author : Laura L. Murphy,Andrzej Bartke
Publisher : CRC Press
Page : 648 pages
File Size : 47,6 Mb
Release : 2019-06-04
Category : Science
ISBN : 9781000012996

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Marijuana/Cannabinoids by Laura L. Murphy,Andrzej Bartke Pdf

First Published in 1992, Marijuana/Cannabinoids: Neurophysiology and Neurobiology is the first book to specifically address the effects of marijuana and cannabinoids on the physiology and behavior of the brain. The book discusses the dramatic effects of marijuana use on brain chemistry, pharmacology, and behavior. It also examines the isolation of natural cannabinoids and the synthesis of new cannabinoid-like compounds that have been important in research leading to the discovery and function of the cannabinoid receptor in the brain. Up-to-date research findings and in-depth reviews on marijuana and cannabinoids in the brain and their potential therapeutic value make Marijuana/Cannabinoids: Neurophysiology and Neurobiology essential for students, practitioners, and researchers involved in researching drugs of abuse.

Marijuana and Medicine

Institute of Medicine
Marijuana and Medicine Book PDF

Author : Institute of Medicine
Publisher : National Academies Press
Page : 288 pages
File Size : 42,5 Mb
Release : 1999-07-10
Category : Medical
ISBN : 9780309071550

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Marijuana and Medicine by Institute of Medicine Pdf

The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

The Health Effects of Cannabis and Cannabinoids

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
The Health Effects of Cannabis and Cannabinoids Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publisher : National Academies Press
Page : 487 pages
File Size : 49,6 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780309453073

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The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Therapeutic Uses of Cannabis

British Medical Association
Therapeutic Uses of Cannabis Book PDF

Author : British Medical Association
Publisher : CRC Press
Page : 164 pages
File Size : 40,6 Mb
Release : 1997-11-18
Category : Medical
ISBN : 9057023180

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Therapeutic Uses of Cannabis by British Medical Association Pdf

At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

Cannabinoids and Pain

Samer N. Narouze
Cannabinoids and Pain Book PDF

Author : Samer N. Narouze
Publisher : Springer Nature
Page : 339 pages
File Size : 44,5 Mb
Release : 2021-07-01
Category : Medical
ISBN : 9783030691868

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Cannabinoids and Pain by Samer N. Narouze Pdf

This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

Phytocannabinoids

A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi
Phytocannabinoids Book PDF

Author : A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi
Publisher : Springer
Page : 131 pages
File Size : 45,5 Mb
Release : 2017-01-24
Category : Science
ISBN : 9783319455419

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Phytocannabinoids by A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi Pdf

The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.

A Psychiatrist's View of Marijuana

Timmen Cermak
A Psychiatrist s View of Marijuana Book PDF

Author : Timmen Cermak
Publisher : Cambridge University Press
Page : 257 pages
File Size : 53,9 Mb
Release : 2020-04-02
Category : Medical
ISBN : 9781108735735

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A Psychiatrist's View of Marijuana by Timmen Cermak Pdf

An essential guide covering the scientific knowledge and communication skills required to deliver objective patient advice about marijuana use.

Cannabis Therapy in Veterinary Medicine

Stephen Cital,Katherine Kramer,Liz Hughston,James S. Gaynor
Cannabis Therapy in Veterinary Medicine Book PDF

Author : Stephen Cital,Katherine Kramer,Liz Hughston,James S. Gaynor
Publisher : Springer Nature
Page : 343 pages
File Size : 43,6 Mb
Release : 2021-05-16
Category : Science
ISBN : 9783030683177

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Cannabis Therapy in Veterinary Medicine by Stephen Cital,Katherine Kramer,Liz Hughston,James S. Gaynor Pdf

This book provides in-depth information on the applications of cannabis products as a legitimate medicine in treating a variety of diseases and disorders in domestic animals. Pharmacology and toxicology of cannabinoids and their effects on the endocannabinoid system, which is involved in the regulation of diverse physiological and cognitive processes, are discussed in detail. Furthermore, the book reviews development and testing of cannabis based medical products and introduces the nutritional components of cannabis plants. Cannabis as a therapeutic in veterinary medicine is gaining interest among owners and practitioners. Numerous studies have been completed or are currently underway that analyze the potential of clinical application of cannabinoid and terpenoid molecules. In this book the authors take a comprehensive look at previous studies in animal and human models and discuss translational applications based on these scientific data. This seminal text serves as a go-to resource for veterinary practitioners on cannabinoid therapy. It will also serve as a foundation for clinicians and researchers interested in this emerging field of veterinary medicine.

The Endocannabinoid System

Eric Murillo-Rodríguez
The Endocannabinoid System Book PDF

Author : Eric Murillo-Rodríguez
Publisher : Academic Press
Page : 256 pages
File Size : 46,8 Mb
Release : 2017-05-12
Category : Nature
ISBN : 9780128096673

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The Endocannabinoid System by Eric Murillo-Rodríguez Pdf

The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy examines the cellular, biochemical, genetic, and therapeutic aspects of the endocannabinoid system. The chapters cover significant conceptual advances in the endocannabinoid field and shed light on the many brain disorders in which this biological system is involved. Written by world-leading experts in the field, the topics covered in this book will have a positive impact on the area of molecular biology, including, but not limited to, cell biology, neuroscience, pharmacology, signaling, disease mechanisms, and therapeutics. Provides an introduction to endocannabinoids in the central nervous system and an overview to their functions in the brain Presents information on neurobiological and cellular studies on the role of the cannabinoid signaling system and its implications in human diseases Includes well-written overviews of the basics of endocannabinoid system structure and function Contains well-illustrated material, with diagrams, charts, and tables Explores compelling case studies and their application to chapters written by experts