Cannabinoid Pharmacology

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Cannabinoid Pharmacology

Anonim
Cannabinoid Pharmacology Book PDF

Author : Anonim
Publisher : Academic Press
Page : 492 pages
File Size : 55,9 Mb
Release : 2017-08-18
Category : Medical
ISBN : 9780128112335

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Cannabinoid Pharmacology by Anonim Pdf

Cannabinoid Pharmacology, Volume 80 is a new volume in the Advances in Pharmacology that presents reviews of recent breakthroughs. This volume aims to present current knowledge of the endogenous cannabinoid system, and looks at molecular, cellular, tissue and organismal effects of endogenous and exogenous cannabinoids. Topics of note in this new volume include Endocannabinoids and their congeners, Endocannabinoid turnover, Plant cannabinoids, Synthetic cannabinoids and ‘legal highs’, CB1 and CB2 cannabinoid receptors, Novel signaling modalities, Novel cannabinoid receptors, and Ion channel regulation by cannabinoids. There is a broad coverage of the essential elements associated with the cannabinoid system. The Editors have sought to include authors who represent authoritative voices on these themes, but have not previously worked together to allow a fresh approach to the individual aspects covered. Presents reviews of recent breakthroughs in the cannabinoid system Features chapters from the best authors in the field Provides an essential resource for scientists, advanced undergraduate students through to established faculty members

Cannabis and Cannabinoids

Ethan B Russo
Cannabis and Cannabinoids Book PDF

Author : Ethan B Russo
Publisher : Routledge
Page : 443 pages
File Size : 41,7 Mb
Release : 2013-09-05
Category : Health & Fitness
ISBN : 9781136614941

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Cannabis and Cannabinoids by Ethan B Russo Pdf

Study the latest research findings by international experts!This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world’s foremost researchers.Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. This book discusses the scientific basis for marijuana’s use in cases of pain, nausea, anorexia, and cachexia. It also explores its possible benefits in glaucoma, ischemia, spastic disorders, and migraine.Cannabis and Cannabinoids examines all facets of the medical use of marijuana, including: botany history biochemistry pharmacology clinical use toxicology side effectsCannabis and Cannabinoids is a reference work that will become indispensable to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public. No other book available offers this comprehensive, even-handed look at a deeply divisive subject.

Cannabinoids as Therapeutics

Raphael Mechoulam
Cannabinoids as Therapeutics Book PDF

Author : Raphael Mechoulam
Publisher : Springer Science & Business Media
Page : 278 pages
File Size : 49,5 Mb
Release : 2006-03-30
Category : Medical
ISBN : 9783764373580

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Cannabinoids as Therapeutics by Raphael Mechoulam Pdf

Only a few years ago the endocannabinoid system was unknown. Today we are aware that endocannabinoids are involved in many of the functions of the mammalian body - in neuroprotection, appetite and suckling, pain, reproduction, anxiety, memory, bone formation etc. This volume presents an up-to-date picture of some of the major fields of endocannabinoid research. It summarizes the actions of the endocannabinoids on various physiological systems and opens new therapeutic windows to a large number of diseases. The first chapter, on the use of Cannabis in India, can be viewed as an expression of thanks to the herbal practitioners, who for centuries passed on the medical traditions associated with the drug. The chapter on chemistry is a short summary of active plant, synthetic and endogenous cannabinoids being investigated today, many of which are mentioned later in the book. Cannabidiol is an unusual cannabinoid - it does not bind to the known receptors and yet exerts a variety of effects. Hence a chapter is devoted to it. Further chapters deal with the endocannabinoid system and the endocannabinoids in a variety of conditions and physiological systems. The concluding chapter describes the research done on Sativex®, a standardized plant extract, shortly to be introduced in Canada as a drug for multiple sclerosis. The intended audience is drug researchers (medicinal chemists, pharmacologists, clinicians), neuroscientists, physiologists, and clinicians interested in the effect of the endocannabinoid system in various physiological systems.

Cannabinoids

Roger G. Pertwee
Cannabinoids Book PDF

Author : Roger G. Pertwee
Publisher : Springer Science & Business Media
Page : 762 pages
File Size : 44,5 Mb
Release : 2005-12-28
Category : Medical
ISBN : 9783540265733

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Cannabinoids by Roger G. Pertwee Pdf

Less than 20 years ago the ?eld of cannabis and the cannabinoids was still c- sidered a minor, somewhat quaint, area of research. A few groups were active in the ?eld, but it was already being viewed as stagnating. The chemistry of cannabis 9 9 was well known, ? -tetrahydrocannabinol (? -THC), identi?ed in 1964, being the only major psychoactive constituent and cannabidiol, which is not psychoactive, possibly contributing to some of the effects. These cannabinoids and several s- thetic analogs had been thoroughly investigated for their pharmacological effects. Their mode of action was considered to be non-speci?c. The reasons for this - sumption were both technical and conceptual. On the technical side, it had been shown that THC was active in both enantiomeric forms (though with a different level of potency) and this observation was incompatible with action on biological substrates—a receptor, an enzyme, an ion channel—which react with a single stereoisomer only. The conceptual problem related to THC activity. This had been pointed out by several highly regarded research groups that had shown that many of the effects seen with cannabinoids were related to those of biologically active lipophiles, and that many of the effects of THC, particularly chronic ones, were comparable to those seen with anaesthetics and solvents.

Cannabinoids

Vincenzo Di Marzo
Cannabinoids Book PDF

Author : Vincenzo Di Marzo
Publisher : John Wiley & Sons
Page : 326 pages
File Size : 55,9 Mb
Release : 2014-08-11
Category : Science
ISBN : 9781118451298

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Cannabinoids by Vincenzo Di Marzo Pdf

'Cannabinoids' is a broad term covering a group of natural products from Cannabis sativa, one of which locks on to specific receptors – protein molecules on the surface of cells – known as cannabinoid receptors. Over the past decades scientists have found that cannabinoid receptors and their endogenous ligands, the endocannabinoids, are involved in a vast array of physiological functions, including helping to control brain activity, energy metabolism, heart function, the immune system and even reproduction. In Cannabinoids, Vincenzo Di Marzo has assembled contributions from international experts to provide the definitive guide to what continues to be a rapidly developing research field. After an introductory historical chapter, the book continues by looking at the biochemical, genetic and molecular elements of cannabinoids, followed by chapters covering their role in health and disease. The final chapter outlines the need for a new nomenclature to reflect the complex and multi-disciplinary nature of this area.

Marijuana and the Cannabinoids

Mahmoud A. ElSohly
Marijuana and the Cannabinoids Book PDF

Author : Mahmoud A. ElSohly
Publisher : Springer Science & Business Media
Page : 322 pages
File Size : 49,5 Mb
Release : 2007-11-15
Category : Medical
ISBN : 9781592599479

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Marijuana and the Cannabinoids by Mahmoud A. ElSohly Pdf

Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC in 1964. The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.

The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects

Stig Agurell
The Cannabinoids Chemical Pharmacologic and Therapeutic Aspects Book PDF

Author : Stig Agurell
Publisher : Academic Press
Page : 932 pages
File Size : 47,8 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323141987

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The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects by Stig Agurell Pdf

The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects provides a comprehensive discussion of the various aspects of cannabis and its constituents. The book is organized into six sections. Section I covers the clinical aspects of cannabis including the health aspects, impact on memory function, and the characteristics and treatment of marijuana abusers. Section II on chemical aspects includes studies on the chemistry and structure-activity relationships of cannabinoids; smoking characteristics of marijuana cigarettes; and developments in cannabinoid analyses of body fluids. Section III on metabolic and pharmacokinetic aspects includes studies on the metabolism, disposition, and pharmacokinetics of delta-9-tetrahydrocannabinol (THC) in men and women; single dose kinetics of cannabidiol in man; and distribution and disposition of THC in different tissues of the rat. Section IV on reproductive aspects include studies on the effects of chronic administration of THC on the early embryonic development of mice; effects of cannabinoids on spermatogenesis in mice; and possible mechanism for the cellular effects of marijuana on male reproductive function. Section V on neuropharmacologic aspects includes studies on the discriminative stimulus properties of THC and the effects of cannabinoids on neurotransmitter receptors in the brain. Section VI on therapeutic aspects includes studies such as the possible anxiolytic effects of cannabidiol; tetrahydrocannabinol effects on extrapyramidal motor behaviors in Parkinson's disease; and the use of cannabinoids in glaucoma.

The Cannabinoid Receptors

Patricia H. Reggio
The Cannabinoid Receptors Book PDF

Author : Patricia H. Reggio
Publisher : Springer Science & Business Media
Page : 407 pages
File Size : 43,9 Mb
Release : 2008-11-09
Category : Medical
ISBN : 9781597455039

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The Cannabinoid Receptors by Patricia H. Reggio Pdf

As research has progressed, the cannabinoid CB 1 and CB 2 receptors have expanded significantly in importance within the neuroscience mainstream. In The Cannabinoid Receptors, leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structure activity relationships, the molecular pharmacology of the cannabinoid receptors and the endocannabinoid system, and ultimately, the whole animal pharmacology and therapeutic applications for cannabinoid drugs. Adding to those key topics, the book also examines the current direction of the field with chapters on new putative cannabinoid receptors and challenges for future research. As a part of The Receptors TM series, this volume highlights its receptor with the most thorough, focused and essential information available. Comprehensive and cutting-edge, The Cannabinoid Receptors serves as an ideal guidebook to what continues to be a fascinating and vital field.

Handbook of Cannabis

Roger G. Pertwee
Handbook of Cannabis Book PDF

Author : Roger G. Pertwee
Publisher : Oxford University Press, USA
Page : 781 pages
File Size : 51,6 Mb
Release : 2014
Category : Medical
ISBN : 9780199662685

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Handbook of Cannabis by Roger G. Pertwee Pdf

In addition it also examines the complex morphology, cultivation, harvesting, and processing of cannabis and the ways in which the plant's chemical composition can be controlled. As well as offering a raft of scientific information there is extensive coverage of cannabinoid-based medicines. Helping readers to identify and evaluate their benefits, chapters explore pharmacological actions and the effects that seem to underlie approved therapeutic uses, how they are currently used to treat certain disorders, and the ever-growing number of wide-ranging potential clinical applications. There is also coverage of both the legal and illegal sources of cannabis, including 'coffee shops' and 'cannabis dispensaries'. The complex issue of 'recreational cannabis' is also tackled.

Therapeutic Uses of Cannabis

British Medical Association
Therapeutic Uses of Cannabis Book PDF

Author : British Medical Association
Publisher : CRC Press
Page : 160 pages
File Size : 52,6 Mb
Release : 2020-08-17
Category : Medical
ISBN : 9781000159653

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Therapeutic Uses of Cannabis by British Medical Association Pdf

At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

The Biology of Marijuana

Emmanuel S Onaivi
The Biology of Marijuana Book PDF

Author : Emmanuel S Onaivi
Publisher : CRC Press
Page : 1007 pages
File Size : 53,6 Mb
Release : 2002-04-18
Category : Medical
ISBN : 9781134481149

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The Biology of Marijuana by Emmanuel S Onaivi Pdf

Marijuana is the prototypical cannabinoid, and is one of the most widely used drugs in the world. Interestingly, cannabinoids are molecules found naturally in the human body and brain as well as in cannabis. This book provides an extensive reference on the biology of marijuana and the role of molecular techniques in elucidating neuropharmaco

Marijuana/Cannabinoids

Laura L. Murphy,Andrzej Bartke
Marijuana Cannabinoids Book PDF

Author : Laura L. Murphy,Andrzej Bartke
Publisher : CRC Press
Page : 604 pages
File Size : 51,5 Mb
Release : 2019-06-04
Category : Science
ISBN : 9781000006179

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Marijuana/Cannabinoids by Laura L. Murphy,Andrzej Bartke Pdf

First Published in 1992, Marijuana/Cannabinoids: Neurophysiology and Neurobiology is the first book to specifically address the effects of marijuana and cannabinoids on the physiology and behavior of the brain. The book discusses the dramatic effects of marijuana use on brain chemistry, pharmacology, and behavior. It also examines the isolation of natural cannabinoids and the synthesis of new cannabinoid-like compounds that have been important in research leading to the discovery and function of the cannabinoid receptor in the brain. Up-to-date research findings and in-depth reviews on marijuana and cannabinoids in the brain and their potential therapeutic value make Marijuana/Cannabinoids: Neurophysiology and Neurobiology essential for students, practitioners, and researchers involved in researching drugs of abuse.

Recent Advances in Cannabinoid Physiology and Pathology

Anna N. Bukiya
Recent Advances in Cannabinoid Physiology and Pathology Book PDF

Author : Anna N. Bukiya
Publisher : Springer
Page : 167 pages
File Size : 54,7 Mb
Release : 2019-07-22
Category : Science
ISBN : 9783030217372

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Recent Advances in Cannabinoid Physiology and Pathology by Anna N. Bukiya Pdf

The cannabinoid system plays a central role in a wide variety of physiological functions that touch upon cardiovascular, gastrointestinal, immune, and nervous systems. Cannabinoids also play a central role in developmental physiology, management of pain, and shaping of human behaviour. Recent movements towards legalization of marijuana use have bolstered scientific interest in the cannabinoid field and led to research efforts that would unveil multi-faceted effects and mechanisms of cannabinoid presence in different organs and at various stages of development. This book summarizes the recent advances in the field of cannabinoid research at multiple levels of resolution. It spans from systemic effects of cannabinoids on development, physiological function, and prevalent pathophysiological conditions to mechanisms that govern cannabinoid interaction with their relevant protein targets at atomic resolution. This book will be of interest to a specialized audience in the fields of biochemistry, pharmacology and developmental biology but alsoto a wider readership with interest in general physiology and cannabinoid signalling in biological systems.

Endocannabinoids

Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
Endocannabinoids Book PDF

Author : Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo
Publisher : CRC Press
Page : 592 pages
File Size : 42,8 Mb
Release : 2005-11-01
Category : Science
ISBN : 1420023640

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Endocannabinoids by Emmanuel S Onaivi,Takayuki Sugiura,Vincenzo Di Marzo Pdf

Over the past decade, there have been major advances in understanding the mechanisms whereby marijuana interacts with the brain in producing psychoactive and potentially therapeutic effects. The discovery of specific gene coding for cannabinoid receptors activated by smoking marijuana, and the finding of endogenous cannabinoids, which also activate the receptors, have transformed cannabinoid research into mainstream science with significant implications in human health and disease Endocannabinoids: The Brain and Body’s Marijuana and Beyond documentsadvances in the discovery and functioning of naturally occurring marijuana-like substances in human biology. It explores recent findings that point to the existence of an endocannabinoid physiological control system (EPCS) that directly impacts human development, health, and disease. While cannabinoid effects on the brain have received the greatest attention throughout the literature, this work looks at research on the endogenous cannabinoid system’s association across all of human physiology, including the immune, endocrine, and reproductive systems. With thoroughly researched and exceptionally insightful contributions from more than three-dozen top-flight researchers representing a cross-section of disciplines from molecular biology, genetics, and neurology to gynecology, physiology, and pharmacology, this work explores a range of topics as wide as the human body is complex. These topics include the EPCS’s relation to cell development and regulation, CNS function, immune function modulation, reproduction, and digestion, as well as its function in mental illness, neurodegenerative diseases, and cancer. The final section in the book considers the significance of endogenous cannabinoids found in some of the simplest multicellular organisms in the animal kingdom, as well as in mammalian cells at the earliest stages of development, all of which suggests that they play a fundamental role in human biology. Enocannabinoids: The Brain and Body’s Marijuana and Beyond explores areas that few books have ventured into, providing cutting-edge information that will ultimately help us better understand human biology at the systemic and perhaps even cellular level, as well as lead to the development of a whole new range of medications.

Phytocannabinoids

A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi
Phytocannabinoids Book PDF

Author : A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi
Publisher : Springer
Page : 131 pages
File Size : 47,7 Mb
Release : 2017-01-24
Category : Science
ISBN : 9783319455419

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Phytocannabinoids by A. Douglas Kinghorn,Heinz Falk,Simon Gibbons,Jun'ichi Kobayashi Pdf

The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.