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Author : May Sherman
Publisher : Unknown
Page : 152 pages
File Size : 55,6 Mb
Release : 1970
Category : Angiotensin
ISBN : PURD:32754081210530
Author : Hideshi Kobayashi,Yoshio Takei
Publisher : Springer Science & Business Media
Page : 251 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642611643
The renin-angiotensin system and the mechanisms regulating this system developed during the adaptive evolution of verte brates, along with many other systems involved in the in tegrated survival of the organism. Because animal species have evolved from common ancestral populations, a basis for the comparison of body structures and physiological processes ex ists among animal groups belonging to different classifications. The comparative approach provides a better understanding of the structure and function of adaptive systems and facilitates the development of general principles governing these systems among animal groups; further, this approach reveals significant characteristics specific to certain animal groups. As the evolu tion of adaptation of animals to environmental conditions is explored, directions for future research are suggested. In this book, advances in research on the renin-angiotensin system are described with emphasis on the comparative aspects. However, since studies on the renin-angiotensin system of birds, reptiles, amphibians and fishes are limited compared with those con ducted in mammals, in some chapters descriptions are con cerned primarily with mammals. It has taken a long time to write this volume, and the topic is a broad one, with new data always emerging; therefore, certain aspects, and sometimes the most recent information, may not be included. Chapters 1-3 and sections 8. 1-8. 4,8. 6, 8. 7 were written by H. K. ; Chapters 4-7 and Section 8. 5 by Y. T. ; Chapter 9 was written by both authors. H. Uemura, M. Nozaki, Y. Okawara, We are indebted to Drs.
Author : Aleksandar Kibel
Publisher : BoD – Books on Demand
Page : 179 pages
File Size : 55,7 Mb
Release : 2020-08-19
Category : Medical
ISBN : 9781789854213
Selected Chapters from the Renin-Angiotensin System aims to provide a comprehensive overview of the most important physiological and pathophysiological roles of the renin-angiotensin system (RAS). The complex and convoluted RAS has been investigated for many years and, through rigorous scientific research, many important and previously unknown components and functions of the RAS have come to light. These discoveries have been crucial in the understanding of this system and provide a basis for effective modulation of the system as part of therapeutic strategies for a number of widespread disorders. New studies are continuing to elucidate the RAS and the mechanisms associated with its functions. This book discusses relevant scientific knowledge about the RAS and intends to introduce the reader to cutting-edge research with an accentuation on the mechanisms at the functional/physiological and molecular/cellular levels.
Author : Sukhwinder K. Bhullar,Paramjit S. Tappia,Naranjan S. Dhalla
Publisher : Springer Nature
Page : 499 pages
File Size : 40,6 Mb
Release : 2023-03-14
Category : Medical
ISBN : 9783031236211
This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.
Author : Frank C. Mooren
Publisher : Springer
Page : 0 pages
File Size : 42,8 Mb
Release : 2012-04-19
Category : Medical
ISBN : 3540360654
The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.
Author : Naranjan S. Dhalla,Sukhwinder K. Bhullar,Anureet K. Shah
Publisher : Springer Nature
Page : 453 pages
File Size : 45,9 Mb
Release : 2023-01-01
Category : Medical
ISBN : 9783031149528
This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
Author : Edward D. Frohlich,Richard N. Re
Publisher : Springer Science & Business Media
Page : 187 pages
File Size : 43,7 Mb
Release : 2009-09-18
Category : Medical
ISBN : 9781441905284
Until recently, the renin-angiotensin-aldosterone system has been considered a systemic endocrine hormonal system exclusively. It is now known that each component of the renin-angiotensin system is produced, synthesized and indeed, present in many organisms including the heart and vessels. This volume presents the most recent clinical and laboratory experiences of the leading physicians and investigators in the field of the local cardiac renin-angiotensin aldosterone system. Cardiovascular, renal and hypertension oriented physicians, investigators and scientists would find this book of interest. Edward D. Frohlich, M.D., M.A.C.P, F.A.C.C., is the Alton Ochsner Distinguished Scientist at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Professor of Medicine and of Physiology at Louisiana State University School of Medicine, New Orleans, and Clinical Professor of Medicine and Adjunct Professor of Pharmacology at Tulane University School of Medicine, New Orleans. He is past Editor-in-Chief of the American Heart Association journal HYPERTENSION. Richard N. Re, M.D., is the Section Head, Hypertension at the Ochsner Clinic Foundation in New Orleans, Louisiana. He is also Ochsner's Scientific Director of Research.
Author : Ahsan Husain,Robert M. Graham
Publisher : CRC Press
Page : 420 pages
File Size : 47,9 Mb
Release : 2003-09-02
Category : Medical
ISBN : 9781482284089
Since 1898, when Tigerstadt and Bergman first extracted renin from rabbit kidney, the reninrugs, Enzymes and Receptors of the Renin is designed to highlight molecular and clinical approaches to understanding the renin Chapter topics have been specifically chosen to cover selected contemporary, controversial and unresolved issues. A novel and uni
Author : Ann Göransson
Publisher : Unknown
Page : 31 pages
File Size : 44,8 Mb
Release : 1985
Category : Electronic
ISBN : 9155416950
Author : Samy I. McFarlane
Publisher : BoD – Books on Demand
Page : 170 pages
File Size : 40,8 Mb
Release : 2021-11-24
Category : Medical
ISBN : 9781839682865
The Renin-Angiotensin Aldosterone System (RAAS) plays an important role not only in salt and water homeostasis but also in the cardiovascular system, the kidney, and the brain. While several volumes address different aspects of the RAAS function, this book provides cutting-edge information on the pathogenesis of various disorders related to RAAS overactivation. It also presents unique aspects of RAAS functioning that have not been sufficiently described in the literature. Topics covered include assessment of hypoaldosteronism in infancy, RASS and cognitive decline, and the role of RAAS in the pathogenesis of COVID-19. Written by experts in the field in an easy-to-follow and illustrated format, this volume will benefit students and practitioners, as well as clinical and basic science investigators alike.
Author : Mohan K. Raizada
Publisher : CRC Press
Page : 591 pages
File Size : 50,6 Mb
Release : 2018-01-18
Category : Science
ISBN : 9781351078948
Cellular and Molecular Biology of the Renin-Angiotensin System provides the first review and update of the state-of-the-art cellular and molecular aspects of the renin-angiotensin system. The book presents detailed analyses from world experts on each component of this system, including future directions. Topics range from angiotensin II receptor subtypes to processing of renin to the use of transgenic animal models for studying the role of this system in hypertension. Cellular and Molecular Biology of the Renin-Angiotensin System is essential reading for physiologists of the renin-angiotensin system, endocrinologists, cardiovascular specialists, renal physiologists, and neurobiologists.
Author : James Ian Summers Robertson,M. Gary Nicholls
Publisher : Mosby
Page : 694 pages
File Size : 41,5 Mb
Release : 1993
Category : Medical
ISBN : UOM:39015032553862
This is a detailed, state-of-the-art account of the renin-angiotensin system. It covers all aspects of the subject by describing contemporary research whilst also emphasising historical perspectives. Volume One considers scientific aspects such as structure, function, evolution, biochemistry and genetics; Volume two details the pathophysiology of the system and describes how knowledge of the RAS is being applied practically to therapeutic techniques. Each chapter is fully illustrated as appropriate: tables, algorithms, graphs, conceptual artworks and black and white photographs are all used. Where colour photographs are included, they are presented in a plate section at the front of the volume.
Author : Po Sing Leung
Publisher : Springer Science & Business Media
Page : 310 pages
File Size : 44,6 Mb
Release : 2007-10-16
Category : Medical
ISBN : 9781402063725
The primary aim of this book is to provide a topical and timely forum for the critical appraisal of an area of renin-angiotensin system (RAS) research that is expanding rapidly. In this respect, a collection of thirteen chapters from distinguished and world-class experts in the field has been presented on the contemporary research of the RAS and their implications in human disease. This book is an indispensable tool tailor-made for specialists, non-specialists and the novice.
Author : Brian Harvey,Frederic Jaisser
Publisher : BoD – Books on Demand
Page : 302 pages
File Size : 47,6 Mb
Release : 2019-09-25
Category : Medical
ISBN : 9781839621987
This book is an open access dissemination of the EU COST Action ADMIRE in Aldosterone/Mineralocorticoid Receptor (MR) physiology and pathophysiology. Aldosterone is the major hormone regulating blood pressure. Alterations in blood levels of aldosterone and genetic mutations in the MR receptor are major causes of hypertension and comorbidities. Many of the drugs in clinical use, and in development for treating hypertension, target aldosterone and MR actions in the kidney and cardiovascular system. The ADMIRE book assembles review chapters from 16 European ADMIRE laboratories providing the latest insights into mechanisms of aldosterone synthesis/secretion, aldosterone/MR physiology and signaling, and the pathophysiological roles of aldosterone/MR activation.
Author : Joseph P. Buckley,Carlos M. Ferrario,Mustafa F. Lokhandwala
Publisher : Elsevier
Page : 625 pages
File Size : 41,6 Mb
Release : 2013-10-22
Category : Nature
ISBN : 9781483160436
Central Actions of Angiotensin and Related Hormones investigates the centrally mediated actions of angiotensin and related hormones in the central nervous system (CNS). Topics covered include angiotensin I converting enzyme activity in the choroid plexus and in the retina; peptide regulation of neuronal excitability; effects of angiotensin-II and angiotensin-III on catecholamine biosynthesis; and humoral kidney mediation of adrenal catecholamine response to hemorrhage. A systems analysis of CNS-angiotensin interaction is also presented. This book is comprised of 51 chapters and opens with a discussion on the results of initial studies undertaken at the University of Pittsburgh to probe the centrally mediated hypertensive response of angiotensin II. The following chapters explore angiotensin receptor sites and angiotensin antagonists, along with the mechanisms involved in changes of blood pressure elicited by hypothalamic stimulation. The effects of angiotensin-II and angiotensin-III on the biosynthesis of catecholamines are also analyzed. The last chapter looks at recommendations regarding the nomenclature of the renin-angiotensin system, especially with respect to the extrarenal tissue enzymes. This monograph will be a valuable source of information for biochemists, biologists, physiologists, and pharmacologists.
