Download Full eBooks in PDF
Retroviruses In Human Lymphoma Leukemia Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Retroviruses In Human Lymphoma Leukemia book. This book definitely worth reading, it is an incredibly well-written.
Author : Masanao Miwa
Publisher : Unknown
Page : 368 pages
File Size : 49,9 Mb
Release : 1985
Category : AIDS (Disease)
ISBN : UCLA:31158011921128
Author : Robert C. Gallo,Myron Essex,Ludwik Gross
Publisher : Cold Spring Harbor Laboratory Press
Page : 432 pages
File Size : 51,7 Mb
Release : 1984
Category : AIDS (Disease)
ISBN : UOM:39015006030228
Author : P.K. Vogt
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642701139
characteristic features in common with the genome of other retroviruses: long terminal repeats (L TR), and coding regions for internal proteins (gag), for re verse transcriptase (pol), and for glycosylated virion surface proteins (env) , ar ranged in the sequence gag, pol, env from the 5' to the 3' end of the genome. However, the HTL V genome also contains some specific features not shared with all other retroviruses: the LTR regions are unusually long (745 base pairs, with 298 base pairs constituting the R region), but unlike the long L TRs of mouse mammary tumor viruses, they do not contain open reading frames. A stretch of noncoding sequences separates the gag and the pol genes. Most interestingly, the HTLV genome contains a region between the 3' end of the env gene and the L TR, called the pX region, that encompasses four open reading frames. Leukemic T cells freshly obtained from patients contain the HTL V provirus but usually do not express it. However, once established in culture, these cells produce viral proteins and release type C particles. Likewise, T cells infected and transformed by HTL V in vitro synthesize virus. Such producing cell lines have been widely used in seroepidemiological surveys and continue to be of importance for detailed studies of viral proteins and nucleic acids.
Author : Masanao Miwa
Publisher : VSP
Page : 358 pages
File Size : 40,9 Mb
Release : 1985-12
Category : Science
ISBN : 9067640573
In the Proceedings of this Symposium, papers are presented from leading laboratories worldwide studying human and animal retroviruses and their associated leukemias and other diseases, including AIDS. The volume provides an up-to-date review of the field and indicates possible future developments for cancer research in which multidisciplinary work, ranging from molecular biology to epidemiology, plays an important role. The book contains 31 papers which are grouped into the following subject areas: lectures; clinical aspects; epidemiology; virus transmission; characterization of viruses; infected cells; AIDS.
Author : William A. Blattner
Publisher : Raven Press (ID)
Page : 520 pages
File Size : 45,9 Mb
Release : 1990
Category : HTLV (Viruses)
ISBN : UOM:39015019396087
Author : Jaquelin Dudley
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 42,9 Mb
Release : 2010-10-22
Category : Medical
ISBN : 9780387095813
This book will contain a series of review articles that focus on retroviral models of human and animal cancers. Each article will be written by an expert in the field of retrovirology. The reviews will summarize current work on a particular retrovirus, with particular emphasis on the relevance of this research to human disease.
Author : Hidesaburo Hanafusa
Publisher : Elsevier
Page : 209 pages
File Size : 46,6 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323160193
Retroviruses and Disease presents a relevant summary of the state of knowledge in both human nonhuman retroviruses. It highlights significant concepts regarding their commonalities and differences in terms of retroviral systems. A section of this book covers the pathogenic human retroviruses and focuses on two. These are HLTV-1 (the first human retrovirus that was isolated) and HIV (the cause of a potent immunological disorder). The life cycle of replication-competent retroviruses, including the murine leukemia viruses and its functions, is discussed in Chapters 1 and 2. The focus of the third chapter is the transformation of Rous sarcoma virus. Meanwhile, Chapter 4 discusses the multiple stages in avian leukosis virus-induced B cell lymphoma. Oncogenes, the molecular basis of human cancer, are also covered in this book. Another virus also discussed in this book is the human T cell leukemia virus. The book is a good reference for students, teachers, specialists, scientists, and researchers in microbiology.
Author : Umberto Bertazzoni,Vincenzo Ciminale,Maria Grazia Romanelli
Publisher : Frontiers Media SA
Page : 225 pages
File Size : 47,8 Mb
Release : 2019-03-25
Category : Electronic
ISBN : 9782889457502
Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered, in 1980, by Gallo and co-workers. About 5-10% of HTLV-1-infected individuals are at risk of developing either a fatal malignancy, adult T-cell leukemia (ATL), or a chronic neuroinflammatory syndrome, HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Both diseases are incurable at present. Many issues concerning HTLV-1’s life cycle and pathobiology are still unsolved or controversial, and new approaches for prognostic stratification of patients and eradication of HTLV-1 infection are in high demand. In this Research Topic, the focus has been centered on discussing two main themes: the functional analysis and oncogenic potential of HTLV-1 regulatory proteins and the control of HTLV-1-associated diseases. The 22 articles in this eBook cover many different aspects of HTLV-1 infection and pathogenesis, providing new perspectives and groundwork for future studies.
Author : Bryan Cullen
Publisher : Oxford University Press
Page : 220 pages
File Size : 53,9 Mb
Release : 1993
Category : Gene Expression Regulation.
ISBN : 0199633827
The first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Author : Rolf Neth,Deutsche Gesellschaft für Hämatologie und Onkologie,Deutsches Krebsforschungszentrum Heidelberg
Publisher : Springer
Page : 592 pages
File Size : 47,7 Mb
Release : 1981
Category : Medical
ISBN : UOM:39015000821606
Author : Takashi Uchiyama,Junji Yodoi
Publisher : Springer
Page : 158 pages
File Size : 55,5 Mb
Release : 1995
Category : Medical
ISBN : UOM:39015035013070
Reviews research in adult T cell leukemia (ATL), one of the central disorders related to infections caused by the retrovirus human T lymphotrophic virus (HTLV-1), for researchers and clinicians. Describes clinical features of ATL and other related diseases and biological properties of cells, explains the IL-2/IL-2 receptor system in ATL and redox regulation and ATL-derived factor, and compares the relationship between AIDS and HIV to ATL and HTLV-1. Includes bandw diagrams and photos. Annotation copyright by Book News, Inc., Portland, OR
Author : Paul Volberding
Publisher : PMPH-USA
Page : 440 pages
File Size : 49,7 Mb
Release : 2006
Category : AIDS (Disease)
ISBN : 1550092561
The precise relationship between viral infection and malignancy remains an epidemiologic association and the subject of active investigation. Nonmalignant hematologic disorders have a similarly complex relationship with cancer-associated viruses and may offer insight into the pathogenesis of oncogenesis. This book explores the relationships between viral infections, immune impairments and the hematologic and malignant diseases, particularly against the backdrop of the HIV epidemic. By extending the scope to all of viral oncology the editors provide an invaluable resource on tumors related to other viruses other than HIV, particularly carcinomas of the cervix and anus with HPV and tumors of the liver with the various hepatitis viruses.
Author : R. Neth,R. C. Gallo,T. Graf,K. Mannweiler,K. Winkler
Publisher : Springer Science & Business Media
Page : 574 pages
File Size : 43,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642679841
Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 21-23, 1982
Author : Irvin S.Y. Chen,Hilary Koprowski,A. Srinivasan,P.K. Vogt
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 48,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642789298
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 40,9 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates