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Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.
Saliva As A Diagnostic Tool by Tharun Varghese Jacob,Sanjaya P.R.,Gokul S. Pdf
"Even though the saliva lacks the drama of blood, sincerity of sweat, emotions of tears saliva should be used as biomarker to detect pregnancy, diabetes mellitus, oral pre cancer & cancer, infectious diseases and also to catch the suspect by eliciting DNA from saliva over the bite marks in forensic odontolgy.This may allow a diagnosis of cancer to be made at an earlier stage, giving patients more choice in various treatment options. Doctors hope that, advancements in salivary diagnostics in the future will replace invasive biopsies and provide new avenues in early detection and diagnosis.It is a perfect medium for surveillance of health and disease. Saliva is ideal for screening premalignant and malignant oral neoplasms because of its anatomical poximity.Saliva contains specific biomarkers associated with either a healthy or diseased state."
Saliva as a Diagnostic Fluid by Daniel Malamud,Lawrence A. Tabak Pdf
Reports on recent advances in detecting drugs, hormones, antibodies, and other molecules of diagnostic importance; research has been going on in such fields as dentistry, clinical chemistry, and steroid hormones, but the researchers have not been talking to each across the disciplinary back fence. A
Saliva is a complex fluid that maintains oral health and has many physiological functions. It is a noninvasive diagnostic fluid as well. Lately, salivary diagnostics has proven its potential to reach clinical practice in the near future for the early detection, diagnosis, and monitoring of various diseases. Salivary Glands - New Approaches in Diagnostics and Treatment is a comprehensive reference, which brings together information on salivary secretion and its disorders, the novel salivary diagnostic methods for numerous diseases, and new techniques in the treatment of salivary diseases. This book contains information for a diverse audience, including dentists, oral biologists, experimental biologists, molecular biologists, oncologists, radiologists, oral and maxillofacial surgeons, and otorhinolaryngologists.
"Spit uncovers the secrets secreting in the many mouths on the globe. From humans to cows to vampire bats to spitting spiders, this book looks at spit from many different angles to provide readers with the fascinating world found in this gross-out subject."--
Advances in Salivary Diagnostics by Charles F. Streckfus Pdf
This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of “salivaomics” is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
Management of Prostate Cancer by Michel Bolla,Hendrik van Poppel Pdf
This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors. The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT. The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.
Author : Douglas A. Granger,Marcus K. Taylor Publisher : Springer Nature Page : 751 pages File Size : 43,7 Mb Release : 2020-04-07 Category : Medical ISBN : 9783030357849
Salivary Bioscience by Douglas A. Granger,Marcus K. Taylor Pdf
This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.
Saliva in Health and Disease by Asta Tvarijonaviciute,Silvia Martínez-Subiela,Pia López-Jornet,Elsa Lamy Pdf
Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.
Oral and Maxillofacial Radiology by David MacDonald Pdf
To the dentist or maxillofacial practitioner, radiology is an essential diagnostic discipline and a valuable tool for treatment planning. Now more than ever, dentists are often the first to encounter lesions of the face and jaws and are frequently held liable for recognizing pathologies and other sites of concern. Oral and Maxillofacial Radiology: A Diagnostic Approach provides clinicians of varied disciplines and skill levels a practical and systematic approach to diagnosing lesions affecting the face and jaws. Firmly grounded in evidence-based research, the book presents a clear understanding of the clinical impact of each lesion within a prospective diagnosis. Oral and Maxillofacial Radiology is logically organized, beginning with the basics of radiological diagnosis before discussing each of the advanced imaging modalities in turn. Modalities discussed include helical and cone-beam computed tomography, magnetic resonance imaging, positron emission tomography, and ultrasonography. Later chapters cover radiological pathologies of the jaw, and also those of the head and neck immediately outside the oral and maxillofacial region. Written by a recognized expert in the field, Oral and Maxillofacial Radiology contains a multitude of clinical images, practical examples, and flowcharts to facilitate differential diagnosis.
An Illustrated Guide to Oral Histology by Imran Farooq,Saqib Ali,Paul Anderson Pdf
An Illustrated Guide to Oral Histology Learn more about the histological presentation of diseased and normal oral tissues with this high definition illustrated dental reference An Illustrated Guide to Oral Histology delivers a collection of high-definition histological and pathological images, presenting both diseased and normal oral tissues. The book provides over 200 high-magnification histomicrographs of oral tissues, as well as definitions and explanations of key identifying histological and pathological features of oral tissues. Readers will also benefit from explanations of the clinical significance of particular features, numerous images of ground sections, haemotoxylin- and eosin-stained sections, and electron images. It also includes core topics such as: An introduction to tooth development, including the bud, cap, early bell, and late bell stages A thorough exploration of enamel, dentin, cementum and dental pulp A discussion of the periodontal ligament, including alveolar crest fibers, horizontal, oblique, apical, and inter-radicular fibers, transseptal fibers, and gingival fibers A guide to alveolar bone, oral mucosa, and salivary glands Perfect for postgraduate dental students, An Illustrated Guide to Oral Histology will also be useful to undergraduate dental students, and those looking to improve their understanding of the microscopic structure of dental tissues and their pathologies.
This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.
