Sepsis Management

Author : Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz
Publisher : Springer
Page : 216 pages
File Size : 43,7 Mb
Release : 2019-02-08
Category : Medical
ISBN : 9783030031435

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Sepsis Management in Resource-limited Settings by Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz Pdf

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Author : Jordi Rello,Jeffrey Lipman,Thiago Lisboa
Publisher : Springer Science & Business Media
Page : 243 pages
File Size : 49,5 Mb
Release : 2011-10-11
Category : Medical
ISBN : 9783642035197

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Sepsis Management by Jordi Rello,Jeffrey Lipman,Thiago Lisboa Pdf

This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

Author : Nicholas S. Ward,Mitchell M. Levy
Publisher : Humana Press
Page : 271 pages
File Size : 43,8 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9783319484709

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Sepsis by Nicholas S. Ward,Mitchell M. Levy Pdf

This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.​

Author : Dr Tan Toh Leong ,Dr Lim Jun Yi
Publisher : Malaysian Sepsis Alliance
Page : 54 pages
File Size : 47,9 Mb
Release : 2023-08-24
Category : Medical
ISBN : 8210379456XXX

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Sepsis Management: A Quick Guide by Dr Tan Toh Leong ,Dr Lim Jun Yi Pdf

Sepsis Management: A Quick Guide for Low-middle income countries (Updated year 2023) is a compilation of information based on our latest local research experience to showcase the importance of sepsis history, epidemic, pathogenesis, comorbidities, diagnostic, monitoring and its management challenges in our local setting of Malaysia. Part 1 reviews the evolution of sepsis, its background, prevalence, definition, host dysregulation response and its identification algorithms. Part 2 focus in its latest evidence of management and its pitfalls. Part 3 mainly focus on continuous hemodynamic monitoring while managing sepsis. Sepsis has been shown to cause serious morbidity and high mortality. Early prediction will enable clinicians to make critical decision and initiate prompt management. This book is suitable for clinicians, paramedics, medical healthcare provider (especially those come from low-middle income countries), medical students, and researchers interested in sepsis research. Each chapter contain useful data which could be applied to our local setting (low-middle income countries. This book can be referred as a handbook for sepsis management to inspire opportunities for future research in this area.

Author : W.J. Sibbald,Jean-Louis Vincent
Publisher : Springer Science & Business Media
Page : 427 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642792243

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Clinical Trials for the Treatment of Sepsis by W.J. Sibbald,Jean-Louis Vincent Pdf

The incidence of sepsis is increasing as new medical and surgical technologies are applied to an increasingly aging patient population. The treatment of sepsis emphasizes strategies to avoid multiple organ dysfunction, with particular attention to establishing source control, and then modifies the host's response to the excessive inflammatory response which characterizes sepsis. This book is a comprehensive review by internationally recognized experts of the epidemiology, monitoring and treatment of sepsis. Using an "evidence-based" approach, it comprises an extensive review of the literature on sepsis, provides up-to-date recommendations for monitoring and treating sepsis patients, and concludes with explicit recommendations for the design and monitoring of future clinical trials.

Author : Patrick Kimuyu
Publisher : GRIN Verlag
Page : 7 pages
File Size : 45,9 Mb
Release : 2018-02-02
Category : Medical
ISBN : 9783668628731

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Sepsis Management. How to treat Sepsis in pharmacological and non-pharmacological ways by Patrick Kimuyu Pdf

Seminar paper from the year 2018 in the subject Medicine - Therapy, grade: 1, Egerton University, language: English, abstract: Sepsis is believed to be one of the most life-threatening medical conditions. This condition is associated with an infection that triggers inflammation responses leading to inflammations in different body parts and organs. In most cases, bacterial infections serve as the causes of sepsis. In practice, sepsis can be viewed as a condition that occur in three stages with sepsis progressing into severe sepsis and then septic shock that is characterized by organ failure. Evidence indicates that incidences for severe sepsis and septic shock have increased rapidly in the past decade and this is attributable to the increase of the aging population. As a result, severe sepsis and septic shock are considered some of the most causes of mortality and morbidity in intensive care. This phenomenon has prompted physicians and professional societies to implement management procedures that focus on early intervention. Therefore, this presentation will provide a comprehensive discussion on pharmacological and non pharmacological treatment of sepsis.

Author : Michael R. Pinsky,Jean-Louis Teboul,Jean-Louis Vincent
Publisher : Springer
Page : 476 pages
File Size : 48,6 Mb
Release : 2019-02-21
Category : Medical
ISBN : 9783319692692

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Hemodynamic Monitoring by Michael R. Pinsky,Jean-Louis Teboul,Jean-Louis Vincent Pdf

This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Author : Antonio Mirijello,Alberto Tosoni
Publisher : Mdpi AG
Page : 146 pages
File Size : 51,9 Mb
Release : 2021-12-27
Category : Medical
ISBN : 3036524835

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New Strategies for Treatment of Sepsis by Antonio Mirijello,Alberto Tosoni Pdf

This book represents a collection of paper from different specialists involved in the management of septic patients, aimed to disseminate the knowledge in the field of sepsis, particularly to non-intensivists physicians.

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 47,7 Mb
Release : 2010
Category : Electronic
ISBN : OCLC:733963734

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Early-onset Neonatal Sepsis by Anonim Pdf

Author : Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz
Publisher : Unknown
Page : 216 pages
File Size : 43,7 Mb
Release : 2019
Category : Septicemia
ISBN : 3030031446

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Sepsis Management in Resource-limited Settings by Arjen M. Dondorp,Martin W. Dünser,Marcus J. Schultz Pdf

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion. .

Author : Jean-Louis Vincent,Jean Carlet,Steven M. Opal
Publisher : Springer Science & Business Media
Page : 848 pages
File Size : 43,6 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306476648

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The Sepsis Text by Jean-Louis Vincent,Jean Carlet,Steven M. Opal Pdf

This textbook is written at the dawn of a new era in the management of sepsis. Recent achievements in the clinical management of septic shock are the culmination of decades of basic and applied research by innovative researchers and clinical investigators worldwide. The contributing authors to this book have spearheaded much of this research and the Editors have endeavored to create a textbook that is comprehensive in nature while maintaining a specific focus upon the multitude of work that constitutes the spectrum of sepsis research including: pathophysiology; monitoring systems; general support; microbial aspects; complications; and anti-sepsis therapies.

Author : Anonim
Publisher : Harvard School of Public Health, Frangois-Xavier Bagnoud Cen
Page : 95 pages
File Size : 40,9 Mb
Release : 2011
Category : Medical
ISBN : 0674061489

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Health Professionals for a New Century by Anonim Pdf

One hundred years ago a series of seminal documents, starting with the Flexner Report of 1910, sparked an enormous burst of energy to harness the power of science to transform higher education in health. Professional education, however, has not been able to keep pace with the challenges of the 21st century. A new generation of reforms is needed to meet the demands of health systems in an interdependent world. The report of the Commission on the Education of Health Professionals for the 21st Century, a global independent initiative consisting of 20 leaders from diverse disciplinary backgrounds and institutional affiliations, articulates a fresh vision and recommends renewed actions. Building on a rich legacy of educational reforms during the past century, the Commission's findings and recommendations adopt a global and multi-professional perspective using a systems approach to analyze education and health, with a focus on institutional and instructional reforms.

Author : Marcus J Schultz,Martin W Dünser,Arjen M Dondorp
Publisher : Unknown
Page : 226 pages
File Size : 41,8 Mb
Release : 2020-10-09
Category : Medical
ISBN : 1013275683

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Sepsis Management in Resource-limited Settings by Marcus J Schultz,Martin W Dünser,Arjen M Dondorp Pdf

This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors - to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Author : Stanislaw P. Stawicki,Mamta Swaroop
Publisher : BoD – Books on Demand
Page : 210 pages
File Size : 54,9 Mb
Release : 2020-06-24
Category : Medical
ISBN : 9781838811709

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Clinical Management of Shock by Stanislaw P. Stawicki,Mamta Swaroop Pdf

Shock is a physiological state of war! From a healthcare provider perspective, the word “shock” is associated with a mixed array of feelings, including dread, well-founded fear, and deep respect. The physiological state of shock is well recognized for the associated destructive consequences, and its successful management requires prompt identification, immediate action, and sustained effort by all members of the healthcare team. This mindset of advanced preparation and constant readiness constitutes the foundation of the modern approach toward shock – early detection and prompt treatment for optimal outcomes. Despite the heterogeneity of “shock” as a clinico-pathological entity, there are some common threads that permeate all forms and manifestations of shock, with apparent increase in observed commonalities in the more advanced (and often irreversible) stages of the systemic syndrome. When faced with shock, the body and its systems do their best to compensate for the maldistribution of oxygen and nutrients. This is known as the so-called compensated shock. Beyond that, the body loses its ability to adjust any further, thus descending into “uncompensated shock,” with a refractory state characterized by vasoplegia and irreversible cardiovascular failure. As the reader journeys through the chapters of the book, he or she will read about various biomarkers and endpoints of resuscitation, explore different types of shock (e.g., septic, hemorrhagic, anaphylactic) and learn about some of the less often discussed topics such as neurogenic and spinal shock, as well as the amniotic fluid embolism. Our goals were to keep things clinically relevant and practically oriented, thus enabling the reader to apply the newly acquired knowledge in their everyday clinical routines. As the reader progresses through the book, we hope to help stimulate further discourse and innovative thinking about the topic. In this context, it is critical that basic, translational, and clinical research on shock continues to advance. Only through ongoing scientific progress can we help improve outcomes for patients with both rare and common forms of shock.

Author : Ghousia Begum
Publisher : BoD – Books on Demand
Page : 250 pages
File Size : 45,9 Mb
Release : 2018-09-05
Category : Medical
ISBN : 9781789236668

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Biomarker by Ghousia Begum Pdf

This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of disease prognosis. Chapters in Part I focus on biomarkers for cancer, including breast cancer and pancreatic cancer, as well as circulating microRNA profiling in cancer biomarker discovery. Chapters in Part II focus on biomarkers of other diagnoses/diseases, including sepsis, childhood renal diseases, pulmonary diseases, Alzheimer's, leishmaniasis, and heart failure. This book investigates the emerging use of biomarkers as a diagnostic tool for the identification of patients with an abnormal condition or as a tool for staging the extent of disease, as an indicator of diseases prognosis. The book is of considerable importance for a broad range of people including researchers, clinicians, and university students.