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Septin Assembly Regulates Cell Cycle Progression Through Activation Of A Protein Kinase Signalling Pathway Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Septin Assembly Regulates Cell Cycle Progression Through Activation Of A Protein Kinase Signalling Pathway book. This book definitely worth reading, it is an incredibly well-written.
Author : Mark Justin Shulewitz
Publisher : Unknown
Page : 384 pages
File Size : 42,6 Mb
Release : 2000
Category : Electronic
ISBN : UCAL:C3447879
Author : Francesc Posas,Angel R. Nebreda
Publisher : Springer Science & Business Media
Page : 322 pages
File Size : 42,9 Mb
Release : 2008-01-24
Category : Science
ISBN : 9783540755692
In this book leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signaling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signaling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis. Written by international experts, the book will appeal to cell biologists and biochemists.
Author : Peter A. Hall,S. E. Hilary Russell,John R. Pringle
Publisher : John Wiley & Sons
Page : 380 pages
File Size : 52,8 Mb
Release : 2008-11-20
Category : Science
ISBN : 0470779691
"The authors represent most of the key figures and the work and the book as a whole is an essential reference for the newcomer or specialist in this area and for any student of eukaryotic cell structure and function. This is an important and wonderful reference." –Microbiology Today, May 2009 Septins are an evolutionarily conserved group of GTP-binding and filament-forming proteins that were originally discovered in yeast. Once the preserve of a small band of yeast biologists, the field has grown rapidly in the past few years and now encompasses the whole of animal and fungal biology. Furthermore, septins are nowadays recognized to be involved in a variety of disease processes from neoplasia to neurodegenerative conditions. This book comprehensively examines the septin gene family and their proteins, providing those new to this research area with a detailed and wide ranging introduction to septin biology. It starts with a unique historical perspective on the development of the field, from its beginnings in the screen for cell division mutants by the Nobel Laureate Lee Hartwell. The evolution of the septin gene family then forms a basis for consideration of the biochemistry and functions of septins in yeast and other model organisms including C. elegans and Drosophila. A major part of the book considers the diversity of septins in mammals, their functions and properties as well as their involvement in normal and abnormal cellular states, followed by a speculative overview from the editors of the key questions in septin research and of where the field may be headed. In addition, several appendices summarise important information for those in, or just entering, the field, e.g. nomenclature and septin and septin-like sequences. This book is an essential source of reference material for researchers in septin biology, cell biology, genetics and medicine, in particular pathology, including areas of neurobiology, oncology, infectious disease and developmental biology.
Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 45,7 Mb
Release : 19??
Category : Electronic
ISBN : 1461464382
Author : Anonim
Publisher : Unknown
Page : 1808 pages
File Size : 53,8 Mb
Release : 2000
Category : Medicine
ISBN : OSU:32436010864948
Author : Christine Guthrie,Gerald R. Fink
Publisher : Unknown
Page : 933 pages
File Size : 44,7 Mb
Release : 1991-01-28
Category : Molecular biology
ISBN : 0123106702
Guide to Yeast Genetics and Molecular Biology presents, for the first time, a comprehensive compilation of the protocols and procedures that have made Saccharomyces cerevisiae such a facile system for all researchers in molecular and cell biology. Whether you are an established yeast biologist or a newcomer to the field, this volume contains all the up-to-date methods you will need to study "Your Favorite Gene" in yeast. Basic Methods in Yeast Genetics**Physical and genetic mapping**Making and recovering mutants**Cloning and Recombinant DNA Methods**High-efficiency transformation**Preparation of yeast artificial chromosome vectors**Basic Methods of Cell Biology**Immunomicroscopy**Protein targeting assays**Biochemistry of Gene Expression**Vectors for regulated expression**Isolation of labeled and unlabeled DNA, RNA, and protein
Author : Anonim
Publisher : Unknown
Page : 846 pages
File Size : 44,7 Mb
Release : 2006
Category : Dissertations, Academic
ISBN : STANFORD:36105123430014
Author : Anonim
Publisher : Unknown
Page : 1940 pages
File Size : 47,6 Mb
Release : 2004
Category : Medicine
ISBN : MINN:31951P009925589
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author : Manoj B. Menon,Matthias Gaestel
Publisher : Frontiers Media SA
Page : 128 pages
File Size : 41,7 Mb
Release : 2017-10-10
Category : Electronic book
ISBN : 9782889452873
Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the budding yeast Saccharomyces cerevisiae, septin family GTPases are expressed and participate in the process of cytokinesis in most eukaryotes except higher plants. More than a dozen septin genes in mammals, together with various splice variants displaying tissue-specific expression patterns and flexible hetero-polymeric higher-order assembly achieve an unfathomable complexity superior to the other cytoskeletal components. Even though the initial studies in the septin field was restricted to their evolutionarily conserved role in cell division, strong expression of septins in the non-dividing cells of the brain generated great interest in understanding their role in neuronal morphogenesis and other aspects of cellular function. On one hand, recent developments indicate complex non-canonical roles for septins in diverse processes ranging from neuronal development to immune response and calcium signaling. On the other hand several lines of data including those from knockout models question the universal role for septins in animal cell cytokinesis. Mammalian hematopoietic cells seem to proliferate and efficiently undergo cytokinesis in the absence of pivotal septin proteins in a context-dependent manner. The lack of septin-dependence of hematopoiesis also opens the possibility of safely targeting septin-dependent cytokinesis for solid-tumor therapy. Thus the septin field is perfectly poised with novel roles for septins being discovered and the basic understanding on septin assembly and its canonical functions constantly revisited. The objective of this research topic was to provide an exclusive platform for discussing these rapid advances in the septin field. With a mixture of reviews and research articles encompassing diverse areas of septin research, ranging from the humble yeast model to human cancer, this ebook will be an interesting reading material for both experts as well as new comers to the septin field.
Author : Manoj B. Menon,Matthias Gaestel
Publisher : Frontiers Media SA
Page : 119 pages
File Size : 42,6 Mb
Release : 2022-07-12
Category : Science
ISBN : 9782889765423
Author : Richard J. Howard,Neil A.R. Gow
Publisher : Springer Science & Business Media
Page : 308 pages
File Size : 51,8 Mb
Release : 2013-03-09
Category : Science
ISBN : 9783662061015
What makes the fungal cell unique among eukaryotes and what features are shared? This volume addresses some of the most persistent and fascinating questions as they pertain to the growth and development of both yeast and hyphal forms of fungi. Beginning with subcellular components, the book moves on to topics including cell organization and polarity. It then moves beyond these matters to examine the cell biology of spores, the biomechanics of invasive growth, and many other subjects.
Author : Cai Huang
Publisher : IntechOpen
Page : 0 pages
File Size : 48,5 Mb
Release : 2012-09-06
Category : Medical
ISBN : 9535107372
15 chapters on protein phosphorylation and human health written by expert scientists. Covers most important research hot points, such as Akt, AMPK and mTOR. Bridges the basic protein phosphorylation pathways with human health and diseases. Detailed and comprehensive text with excellent figure illustration.
Author : Ann Arvin,Gabriella Campadelli-Fiume,Edward Mocarski,Patrick S. Moore,Bernard Roizman,Richard Whitley,Koichi Yamanishi
Publisher : Cambridge University Press
Page : 1325 pages
File Size : 44,6 Mb
Release : 2007-08-16
Category : Medical
ISBN : 9781139461641
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author : David Owen Morgan
Publisher : New Science Press
Page : 328 pages
File Size : 45,9 Mb
Release : 2007
Category : Science
ISBN : 9780878935086
The Cell Cycle: Principles of Control provides an engaging insight into the process of cell division, bringing to the student a much-needed synthesis of a subject entering a period of unprecedented growth as an understanding of the molecular mechanisms underlying cell division are revealed.
Author : Jose C. Jimenez-Lopez
Publisher : BoD – Books on Demand
Page : 344 pages
File Size : 41,9 Mb
Release : 2017-05-17
Category : Science
ISBN : 9789535131694
The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.
