Sickle Cell Syndromes An Issue Of Hematology Oncology Clinics Of North America E Book

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Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Sophie Lanzkron,Jane Little
Publisher : Elsevier Health Sciences
Page : 289 pages
File Size : 45,8 Mb
Release : 2022-11-20
Category : Medical
ISBN : 9780323986649

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Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book by Sophie Lanzkron,Jane Little Pdf

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America

Author : Rachael Grace,Russell Ware
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 47,7 Mb
Release : 2019-05-05
Category : Medical
ISBN : 9780323673341

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Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America by Rachael Grace,Russell Ware Pdf

This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.

Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics,

Author : Elliot Vichinsky
Publisher : Elsevier Health Sciences
Page : 281 pages
File Size : 52,7 Mb
Release : 2014-05-23
Category : Medical
ISBN : 9780323290005

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Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics, by Elliot Vichinsky Pdf

This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; Regulation of ineffective erythropoiesis in iron metabolism; Altering oxygen affinity; Cellular adhesion and the endothelium; Arginine therapy; Role of the hemostatic system on SCD pathophysiology and potential therapeutics; Adenosine signaling and novel therapies; New approaches to correcting ineffective erythropoiesis and iron dysregulation; New approaches to correcting ineffective erythropoiesis and iron dysregulation; Fetal hemoglobin induction; Gene therapy for hemoglobinopathies; and Oxidative injury and the role of antioxidant therapy.

Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America

Author : Sophie Lanzkron,Jane Little
Publisher : Elsevier
Page : 0 pages
File Size : 42,5 Mb
Release : 2022-12-28
Category : Medical
ISBN : 0323986633

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Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America by Sophie Lanzkron,Jane Little Pdf

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America

Author : John C. Perkins,Jonathan E Davis
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 55,6 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9780323611480

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Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America by John C. Perkins,Jonathan E Davis Pdf

This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!

Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Edward J. BenzJr,Vijay G. Sankaran
Publisher : Elsevier Health Sciences
Page : 241 pages
File Size : 54,6 Mb
Release : 2023-03-16
Category : Medical
ISBN : 9780443183218

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Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book by Edward J. BenzJr,Vijay G. Sankaran Pdf

In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes. Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Daniel E. Bauer,Donald B Kohn
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 53,8 Mb
Release : 2017-09-27
Category : Medical
ISBN : 9780323546690

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Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book by Daniel E. Bauer,Donald B Kohn Pdf

This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Global Hematology, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : David J. Roberts,Sir David J. Weatherall
Publisher : Elsevier Health Sciences
Page : 313 pages
File Size : 54,9 Mb
Release : 2016-04-20
Category : Medical
ISBN : 9780323417570

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Global Hematology, An Issue of Hematology/Oncology Clinics of North America, E-Book by David J. Roberts,Sir David J. Weatherall Pdf

This issue will focus on the global state of hematology and will include articles such as: The Global Burden of Anemia, Iron Deficiency Anemia: Problems in Diagnosis and Therapy, Progress Towards the Control and Management of the Thalassemias, Problems and Approaches for Blood Transfusion in the Developing Countries, and many more!

Neutropenia, An Issue of Hematology/Oncology Clinics of North America

Author : Christoph Klein
Publisher : Elsevier Health Sciences
Page : 272 pages
File Size : 40,6 Mb
Release : 2013-02-28
Category : Medical
ISBN : 9781455771875

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Neutropenia, An Issue of Hematology/Oncology Clinics of North America by Christoph Klein Pdf

This issue of Hematology/Oncology Clinics is guest edited by Dr. Christoph Klein and focuses on the topic of Neutropenia. Article titles include: Homeostasis and migration of neutrophil granulocytes,Granulocyte-colony Stimulating Factor (G-CSF) receptor signaling,New Granulocyte-colony Stimulating Factor (G-CSF) Receptor Signaling Pathways ,Neutrophil elastase (ELANE) – Genetics and Pathophysiology,Autosomal recessive variants of Severe congenital neutropenia (SCN),Leukocyte Adhesion Deficiency (LAD), and Genotype-phenotype correlations in Severe congenital neutropenia (SCN).

Congenital and Acquired Disorders of Macrophages and Histiocytes, An Issue of Hematology/Oncology Clinics of North America,

Author : Nancy Berliner
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 50,5 Mb
Release : 2016-01-07
Category : Medical
ISBN : 9780323400893

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Congenital and Acquired Disorders of Macrophages and Histiocytes, An Issue of Hematology/Oncology Clinics of North America, by Nancy Berliner Pdf

This issue of Hematology/Oncology Clinics of North America is devoted to Congenital and Acquired Disorders of Macrophages and Histiocytes. Guest Editors Nancy Berliner, MD and Barrett Rollins, MD have assembled a group of expert authors to review the following topics: Nosology of Langerhans Cell Histiocytosis (LCH); Cell of Origin of LCH; Genomic Changes in LCH; Clinical Treatment of LCH; Neurodegeneration in LCH; Pathogenesis of Hemophagocytic Lymphohistiocytosis (HLH); Familial HLH; HLH in Adults; Macrophage Activation Syndrome; and Stem Cell Transplant for HLH.

Imaging of Neurologic Complications in Hematological Disorders, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Sangam Kanekar
Publisher : Elsevier Health Sciences
Page : 281 pages
File Size : 44,6 Mb
Release : 2016-08-28
Category : Medical
ISBN : 9780323459709

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Imaging of Neurologic Complications in Hematological Disorders, An Issue of Hematology/Oncology Clinics of North America, E-Book by Sangam Kanekar Pdf

This issue of Hematology/Oncology Clinics of North America is devoted to Imaging of Neurological complications in Hematological disorders and will include articles on Blood Dyscriasis: Classification and Clinical Neurological Presentations, Imaging Manifestation of Anemia, CNS Complications of Hemorrhagic and Coagulation Disorders, Neurological and Head and Neck Manifestation of Sickle Cell Disease, Neuroimaging in Lymphoma, and many more!

Myelodysplastic Syndromes An Issue of Hematology/Oncology Clinics of North America

Author : David Steensma
Publisher : Elsevier Health Sciences
Page : 193 pages
File Size : 52,9 Mb
Release : 2020-02-26
Category : Medical
ISBN : 9780323722643

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Myelodysplastic Syndromes An Issue of Hematology/Oncology Clinics of North America by David Steensma Pdf

This issue of Hematology/Oncology Clinics, guest edited by David P. Steensma, will cover key topics in Myelodysplastic Syndromes. This issue is one of six selected each year by our series consulting editors, George P. Canellos and Edward J. Benz. Topics discussed in this issue will include: Novel prognostic models for MDS, Evaluating MDS patients with genetic mutations that might be germline, Implications of splicing mutations in MDS for pathophysiology and therapy, Assessing quality of life in MDS/MPN overlap patients, Creation of a clinic for patients with clonal hematopoiesis, Luspatercept in MDS, Prospects for venetoclax in MDS, Treatment of acquired sideroblastic anemias, Treatment of patients with AML arising from MDS, Targeting TP53 mutations in MDS, among others.

Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Jennifer R. Brown︎
Publisher : Elsevier Health Sciences
Page : 217 pages
File Size : 48,6 Mb
Release : 2021-07-01
Category : Medical
ISBN : 9780323896931

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Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America, E-Book by Jennifer R. Brown︎ Pdf

This issue of Hematology/Oncology Clinics, guest edited by Dr. Jennifer R. Brown?, will focus on Chronic Lymphocytic Leukemia. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue will include: Chronic Lymphocytic Leukemia: Do We Know the Cell of Origin Yet?; Significance of BCR Stereotypy; Prognostic and Predictive Implications of Cytogenetics and Genomics; Role of Epigenetics in Chronic Lymphocytic Leukemia; Genomics of Resistance to Targeted Therapies; First Line Therapy for Chronic Lymphocytic Leukemia; The Ongoing Unmet Needs in Chronic Lymphocytic Leukemia Therapy; BTK Inhibitors; Minimal Residual Disease; Should Undetectable MRD Be the Goal of Chronic Lymphocytic Leukemia Therapy?; Management of Chronic Lymphocytic Leukemia after Progression on BTK Inhibitors; Role of PI3K Inhibitors in Chronic Lymphocytic Leukemia; Can We Restore the Immunodeficiency of Chronic Lymphocytic Leukemia?; and Immune Therapy for Chronic Lymphocytic Leukemia

Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author : Nirali N. Shah,Sung-Yun Pai
Publisher : Elsevier Health Sciences
Page : 273 pages
File Size : 41,6 Mb
Release : 2022-07-19
Category : Medical
ISBN : 9780323987769

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Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book by Nirali N. Shah,Sung-Yun Pai Pdf

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Imaging of Neurologic Complications in Hematological Disorders, an Issue of Hematology/Oncology Clinics of North America

Author : Sangam Kanekar
Publisher : Clinics: Internal Medicine
Page : 0 pages
File Size : 52,6 Mb
Release : 2016-07-27
Category : Medical
ISBN : 0323459692

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Imaging of Neurologic Complications in Hematological Disorders, an Issue of Hematology/Oncology Clinics of North America by Sangam Kanekar Pdf

This issue of Hematology/Oncology Clinics of North America is devoted to Imaging of Neurological complications in Hematological disorders and will include articles on Blood Dyscriasis: Classification and Clinical Neurological Presentations, Imaging Manifestation of Anemia, CNS Complications of Hemorrhagic and Coagulation Disorders, Neurological and Head and Neck Manifestation of Sickle Cell Disease, Neuroimaging in Lymphoma, and many more!