Single Molecule Detection In Solution

Author : Christoph Zander,Jörg Enderlein,Richard A. Keller
Publisher : Wiley-VCH
Page : 398 pages
File Size : 41,6 Mb
Release : 2002-05-06
Category : Science
ISBN : UOM:39015055895729

Get Book

Single Molecule Detection in Solution by Christoph Zander,Jörg Enderlein,Richard A. Keller Pdf

The detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years. This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results. This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme.

Author : W. E. Moerner,M. Orrit,U. P. Wild,Thomas Basché
Publisher : John Wiley & Sons
Page : 264 pages
File Size : 52,9 Mb
Release : 2008-09-26
Category : Science
ISBN : 9783527614707

Get Book

Single-Molecule Optical Detection, Imaging and Spectroscopy by W. E. Moerner,M. Orrit,U. P. Wild,Thomas Basché Pdf

Single Molecule Spectroscopy is one of the hottest topics in today's chemistry. It brings us close to the the most exciting vision generations of chemists have been dreaming of: To observe and examine single molecules! While most of chemistry deals with myriads of molecules, this books presents the latest developments for the detection and investigation of single entities. Written by internationally renowned authors, it is a thorough and comprehensive survey of current methods and their applications.

Author : R. Rigler,M. Orrit,T. Basche
Publisher : Springer Science & Business Media
Page : 375 pages
File Size : 42,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642565441

Get Book

Single Molecule Spectroscopy by R. Rigler,M. Orrit,T. Basche Pdf

The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.

Author : Joseph R. Lakowicz
Publisher : Springer Science & Business Media
Page : 954 pages
File Size : 50,8 Mb
Release : 2007-12-05
Category : Science
ISBN : 9780387463124

Get Book

Principles of Fluorescence Spectroscopy by Joseph R. Lakowicz Pdf

The third edition of this established classic text reference builds upon the strengths of its very popular predecessors. Organized as a broadly useful textbook Principles of Fluorescence Spectroscopy, 3rd edition maintains its emphasis on basics, while updating the examples to include recent results from the scientific literature. The third edition includes new chapters on single molecule detection, fluorescence correlation spectroscopy, novel probes and radiative decay engineering. Includes a link to Springer Extras to download files reproducing all book artwork, for easy use in lecture slides. This is an essential volume for students, researchers, and industry professionals in biophysics, biochemistry, biotechnology, bioengineering, biology and medicine.

Author : Tyler A. Byassee
Publisher : Unknown
Page : 120 pages
File Size : 42,7 Mb
Release : 2002
Category : Electronic
ISBN : IND:30000082012281

Get Book

Probing Single Molecules in Single Living Cells by Tyler A. Byassee Pdf

Author : Chris Gell,David Brockwell,Alastair Smith
Publisher : OUP Oxford
Page : 278 pages
File Size : 54,9 Mb
Release : 2006-08-17
Category : Science
ISBN : 9780191523854

Get Book

Handbook of Single Molecule Fluorescence Spectroscopy by Chris Gell,David Brockwell,Alastair Smith Pdf

Analytical measurements at the single molecule level under ambient conditions have become almost routine in the past few years. The application of this technology to fundamental studies of heterogeneity in biomolecular structure and dynamics, chemical and biological reaction kinetics, and photophysics provides a rich playground for molecular scientists. The potential use of single molecule detection for nanotechnology and quantum information processing is a new and almost unexplored area. This handbook is intended for those interested in a practical introduction to single molecule investigations using fluorescence techniques and places special emphasis on the practicalities of achieving single molecule resolution, analysing the resulting data and exploration of the applications in biophysics. It is ideal for graduate research students and others embarking on work in this exciting field.

Author : Alexander E. Knight
Publisher : Academic Press
Page : 368 pages
File Size : 43,6 Mb
Release : 2009-02-26
Category : Science
ISBN : 008092123X

Get Book

Single Molecule Biology by Alexander E. Knight Pdf

Single molecule techniques, including single molecule fluorescence, optical tweezers, and scanning probe microscopy, allow for the manipulation and measurement of single biological molecules within a live cell or in culture. These approaches, amongst the most exciting tools available in biology today, offer powerful new ways to elucidate biological function, both in terms of revealing mechanisms of action on a molecular level as well as tracking the behaviour of molecules in living cells. This book provides the first complete and authoritative treatment of this rapidly emerging field, explicitly from a biological perspective. The contents are organized by biological system or molecule. Each chapter discusses insights that have been revealed about their mechanism, structure or function by single molecule techniques. Among the topics covered are enzymes, motor proteins, membrane channels, DNA, ribozymes, cytoskeletal proteins, and other key molecules of current interest. An introduction by the editor provides a concise review of key principles and an historical overview. The last section discusses applications in molecular diagnostics and drug discovery. * Organized by biological system or molecule. * Each chapter discusses insights into mechanism of action, structure, and function * Covers enzymes, motor proteins, membrane channels, DNA, ribozymes, etc. * Includes an introduction to key principles and an historical overview. * Discusses applications in molecular diagnostics and drug discovery. * Provides an expert's perspective on future developments.

Author : Matteo Gabba
Publisher : Forschungszentrum Jülich
Page : 197 pages
File Size : 43,5 Mb
Release : 2014-03-28
Category : Electronic
ISBN : 9783893369430

Get Book

Interdomain Functional Dynamics of Phosphoglycerate Kinase Studied by Single-Molecule FRET by Matteo Gabba Pdf

Author : Iddo Heller,David Dulin,Erwin J.G. Peterman
Publisher : Springer Nature
Page : 511 pages
File Size : 48,6 Mb
Release : 2023-11-13
Category : Science
ISBN : 9781071633779

Get Book

Single Molecule Analysis by Iddo Heller,David Dulin,Erwin J.G. Peterman Pdf

This third edition volume expands on the previous editions with new discussions on the latest techniques and developments in the field. The chapters in this book are organized into four parts, and cover topics such as optical tweezers; single-molecule fluorescence tools; atomic force microscopy; magnetic tweezers; applications to virus protein shells, unfolding of proteins, nucleic acids, motor proteins, in vivo and in vitro; and protocols to establish specific surface interactions and perform force calibration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Single Molecule Analysis: Methods and Protocols, Third Edition is a valuable resource for all researchers who want to learn more about this exciting and still expanding field. Chapters 2, 7, 8, 9, 12, 18, and 19 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : Dongqing Li
Publisher : Springer Science & Business Media
Page : 2242 pages
File Size : 49,6 Mb
Release : 2008-08-06
Category : Technology & Engineering
ISBN : 9780387324685

Get Book

Encyclopedia of Microfluidics and Nanofluidics by Dongqing Li Pdf

Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.

Author : Martin Hof,Rudolf Hutterer,V. Fidler
Publisher : Springer Science & Business Media
Page : 315 pages
File Size : 47,6 Mb
Release : 2006-01-27
Category : Science
ISBN : 9783540270041

Get Book

Fluorescence Spectroscopy in Biology by Martin Hof,Rudolf Hutterer,V. Fidler Pdf

Volume 3 of this new series focuses on brandnew research and applications in biology, biophysics and other fields of life sciences. Many frontline researcher have contributed to this highly attractive and interdisciplinary volume which spans the entire field of present fluorescence spectroscopy including nanotechnology, membrane and DNA studies and fluorescence imaging in cancer research.

Author : Peter Hinterdorfer,Antoine van Oijen
Publisher : Springer Science & Business Media
Page : 634 pages
File Size : 45,8 Mb
Release : 2009-12-24
Category : Science
ISBN : 9780387764979

Get Book

Handbook of Single-Molecule Biophysics by Peter Hinterdorfer,Antoine van Oijen Pdf

This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Author : Chris Gell,David Brockwell,Alastair Smith
Publisher : Oxford University Press on Demand
Page : 279 pages
File Size : 55,6 Mb
Release : 2006-08-17
Category : Science
ISBN : 9780198529422

Get Book

Handbook of Single Molecule Fluorescence Spectroscopy by Chris Gell,David Brockwell,Alastair Smith Pdf

This is a practical introduction to single molecule fluorescence experiments, the analysis of the data, and applications of the techniques to the study of biological structure and function.

Author : Anonim
Publisher : Unknown
Page : 178 pages
File Size : 44,7 Mb
Release : 2007
Category : Biomolecules
ISBN : UOM:39015069189648

Get Book

Ultrasensitive and Single-molecule Detection Technologies by Anonim Pdf

Author : Rudolf Rigler,H. Vogel
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 48,6 Mb
Release : 2007-12-07
Category : Technology & Engineering
ISBN : 9783540739241

Get Book

Single Molecules and Nanotechnology by Rudolf Rigler,H. Vogel Pdf

This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including quantum photonics of organic dyes and inorganic nanoparticles and monitoring of single molecule (enzymatic) reactions.