Site Selective Neurotoxicity

Author : David S Lester,William Slikker Jr,Philip Lazarovici
Publisher : CRC Press
Page : 327 pages
File Size : 49,6 Mb
Release : 2002-02-07
Category : Medical
ISBN : 9780203219096

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Site-Selective Neurotoxicity by David S Lester,William Slikker Jr,Philip Lazarovici Pdf

This unique volume provides interdisciplinary coverage of the mechanistic perspective of neurotoxicity that focuses on the site of action of known neurotoxins. It provides the reader with an insight into the common characteristics of neurotoxin action on the nervous system and examines sites of action at three levels of complexity: molecular, cellu

Author : B. Lester
Publisher : Harwood Academic Publishers
Page : 128 pages
File Size : 51,5 Mb
Release : 2002-02
Category : Electronic
ISBN : 9058232220

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Site Selective Neurotoxicity by B. Lester Pdf

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Neurotoxicology and Models for Assessing Risk
Publisher : National Academies Press
Page : 167 pages
File Size : 42,6 Mb
Release : 1992-02-01
Category : Science
ISBN : 9780309045315

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Environmental Neurotoxicology by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Neurotoxicology and Models for Assessing Risk Pdf

Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Author : Michael Aschner,Lucio G. Costa
Publisher : CRC Press
Page : 477 pages
File Size : 40,7 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9781420039740

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The Role of Glia in Neurotoxicity by Michael Aschner,Lucio G. Costa Pdf

Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.

Author : G. Jean Harry,Hugh A. Tilson
Publisher : CRC Press
Page : 334 pages
File Size : 50,6 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420054880

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Neurotoxicology by G. Jean Harry,Hugh A. Tilson Pdf

This new edition presents an integrated approach to neurotoxicology, the study of organisms' responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects - from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs simila

Author : Anonim
Publisher : Academic Press
Page : 1129 pages
File Size : 44,8 Mb
Release : 1997-10-20
Category : Medical
ISBN : 9780080581347

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Catecholamines: Bridging Basic Science with Clinical Medicine by Anonim Pdf

This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.

Author : Robert M. Goodman
Publisher : Routledge
Page : 1360 pages
File Size : 43,8 Mb
Release : 2004-02-27
Category : Technology & Engineering
ISBN : 9781000031584

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Encyclopedia of Plant and Crop Science (Print) by Robert M. Goodman Pdf

Encyclopedia of Plant and Crop Science is the first-ever single-source reference work to inclusively cover classic and modern studies in plant biology in conjunction with research, applications, and innovations in crop science and agriculture. From the fundamentals of plant growth and reproduction to developments in agronomy and agricultural science, the encyclopedia's authoritative content nurtures communication between these academically distinct yet intrinsically related fields-offering a spread of clear, descriptive, and concise entries to optimally serve scientists, agriculturalists, policy makers, students, and the general public. ALSO AVAILABLE ONLINE This Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for both researchers, students, and librarians, including: Citation tracking and alerts Active reference linking Saved searches and marked lists HTML and PDF format options For more information, visit Taylor and Francis Online or contact us to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367 / (E-mail) [email protected] International: (Tel) +44 (0) 20 7017 6062 / (E-mail) [email protected]

Author : Katsunori Tanaka,Kenward Vong
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 48,9 Mb
Release : 2020-04-27
Category : Science
ISBN : 9783527344321

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Handbook of In Vivo Chemistry in Mice by Katsunori Tanaka,Kenward Vong Pdf

Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.

Author : Laurie Hing Man Chan
Publisher : MDPI
Page : 144 pages
File Size : 55,6 Mb
Release : 2019-06-24
Category : Technology & Engineering
ISBN : 9783038979708

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Mercury and Methylmercury Toxicology and Risk Assessment by Laurie Hing Man Chan Pdf

Mercury is a global pollutant that affects the health of both humans and ecosystems. This Special Issue collects three review papers and six research articles that report on the latest findings on the mechanisms of mercury toxicology and its impacts on environmental health. This collection of papers provides useful, new information on the mechanisms of mercury toxicity and methods of improving the risk assessment of mercury exposure.

Author : L. Tatu,J. Bogousslavsky
Publisher : Karger Medical and Scientific Publishers
Page : 244 pages
File Size : 41,8 Mb
Release : 2016-04-04
Category : Medical
ISBN : 9783318056068

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War Neurology by L. Tatu,J. Bogousslavsky Pdf

Interest in the history of neurological science has increased significantly during the last decade, but the significance of war has been overlooked in related research. In contrast, this book highlights war as a factor of progress in neurological science. Light is shed on this little-known topic through accounts given by neurologists in war, experiences of soldiers suffering from neurological diseases, and chapters dedicated to neurology in total and contemporary war. Written by experts, the contributions in this book focus on the Napoleonic Wars, the American Civil War, the Franco-Prussian War of 1870, World Wars I and II, and recent conflicts such as Vietnam or Afghanistan. Comprehensive yet concise and accessible, this book serves as a fascinating read for neurologists, neurosurgeons, psychiatrists, historians, and anyone else interested in the history of neurology.

Author : Anonim
Publisher : Unknown
Page : 528 pages
File Size : 49,7 Mb
Release : 2008
Category : Drug addiction
ISBN : STANFORD:36105131941945

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Drug Addiction by Anonim Pdf

Author : Yehuda Gutman,Philip Lazarovici
Publisher : CRC Press
Page : 520 pages
File Size : 44,7 Mb
Release : 1997-05-22
Category : Science
ISBN : 9057020785

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Toxins and Signal Transduction by Yehuda Gutman,Philip Lazarovici Pdf

Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological effects by interfering with the signal transduction initiated by these chemicals (hormones, transmitters, growth factors, and other mediators). Up-to-date information is provided by outstanding experts, who discuss the molecular mechanisms involved in the action of many toxins, as well as the use of toxins as informative tools with which to study signal transduction and their potential therapeutic usage. This volume contains useful information for the experimentalist interested in toxins or in signal transduction, as well as for the reader interested in gaining a comprehensive overview of the field. The Cellular and Molecular Mechanisms of Toxin Action series will include monographs on signal transduction, secretory systems, cytoskeleton, selective neurotoxicity of natural, recombinant and chimeric toxins giving a broader emphasis on the mechanism of action, structure-function relationship, and use of toxins as research tools and their therapeutic applications.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee
Publisher : National Academies Press
Page : 476 pages
File Size : 48,8 Mb
Release : 1986-02-01
Category : Nature
ISBN : 9780309036870

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Drinking Water and Health, by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee Pdf

The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.

Author : Antonius M. VanDongen
Publisher : CRC Press
Page : 368 pages
File Size : 41,5 Mb
Release : 2008-10-29
Category : Medical
ISBN : 9781420044157

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Biology of the NMDA Receptor by Antonius M. VanDongen Pdf

The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Author : Anonim
Publisher : Unknown
Page : 2212 pages
File Size : 48,8 Mb
Release : 2003
Category : Medicine
ISBN : MINN:31951P00880602J

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Index Medicus by Anonim Pdf

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.