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Author : Roderick J. Hay,Kingsley Asiedu
Publisher : MDPI
Page : 220 pages
File Size : 45,6 Mb
Release : 2019-07-31
Category : Medical
ISBN : 9783039212538
This book is a printed edition of the Special Issue Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge that was published in TropicalMed
Author : Roderick J. Hay,Kingsley Asiedu
Publisher : Unknown
Page : 218 pages
File Size : 40,6 Mb
Release : 2019
Category : Arctic medicine. Tropical medicine
ISBN : 3039212540
This Special Issue explores the range of clinical manifestations and epidemiology of both skin NTDs and common skin disease in endemic regions, the use of common diagnostic and management pathways, the different technologies that play a role in diagnosis and training, the role of patient involvement at a community level, as well as the assessment of the results of different initiatives in the field.
Author : Fingani Annie Mphande
Publisher : Springer Nature
Page : 190 pages
File Size : 47,7 Mb
Release : 2020-05-05
Category : Medical
ISBN : 9789811538797
This book focuses on neglected skin diseases and conditions in resource-poor countries through the lens of livelihoods. These diseases, when neglected, not only affect the skin, but also joint movement and physical appearance, severely influencing the lives and livelihoods of individuals and families in vulnerable communities. The book explores why neglected skin diseases thrive in resource-poor countries, and considers how this cycle might be broken by looking at the impact on livelihoods and access to healthcare in affected communities. The research is shaped by three guiding questions: Firstly, why have some measures been successful in one part of a population and not the other? Secondly, what is unique about vulnerable populations in various parts of the world? And thirdly, can the cycle of debilitating skin diseases and conditions in resource-poor countries be broken? In addressing these concerns, the book excavates past and present efforts in public health measures to combat these diseases, considers the impact of culture and livelihoods, and reviews some of the milestones in disease elimination and eradication. This book will be an indispensable source for health service planners, administrators and practitioners working with vulnerable populations, as well as graduate students and researchers in public health.
Author : World Health Organization
Publisher : World Health Organization
Page : 211 pages
File Size : 48,5 Mb
Release : 2015-08-05
Category : Medical
ISBN : 9789241564861
"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.
Author : Myron Christodoulides
Publisher : Springer Nature
Page : 337 pages
File Size : 51,6 Mb
Release : 2023-03-27
Category : Medical
ISBN : 9783031243554
This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Author : World Health Organization. Department of Control of Neglected Tropical Diseases,World Health Organization
Publisher : World Health Organization
Page : 184 pages
File Size : 44,6 Mb
Release : 2010
Category : Medical
ISBN : 9789241564090
"Neglected tropical diseases (NTDs) blight the lives of a billion people worldwide and threaten the health of millions more. These ancient companions of poverty weaken impoverished populations, frustrate the achievement of health in the Millennium Development Goals and impede global health and economies has convinced governments, donors, the pharmaceutical industry and other agencies, including nongovernmental organizations (NGOs), to invest in preventing and controlling this diverse group of diseases. Global efforts to control "hidden" diseases, such as dracunculiasis (guinea-worm disease), leprosy, gains including the imminent eradication of dracunculiasis. Since 1989 (when most endemic countries began reporting monthly from each endemic village), the number of new dracunculiasis cases has fallen from 892 055 in 12 endemic countries to 3190 in 4 countries in 2009, a decrease of more than 99%. The World Health Organization (WHO) recommends five public-health strategies for the prevention and control of NTDs: preventive chemotherapy; intensified case-management; vector control; the provision of safe water, sanitation and hygiene; and veterinary public health (that is, applying veterinary sciences to ensure the health and well-being of humans). Although one approach and delivered locally." - p. vii
Author : Gerd Pluschke,Katharina Röltgen
Publisher : Springer
Page : 287 pages
File Size : 40,7 Mb
Release : 2019-04-29
Category : Medical
ISBN : 9783030111144
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.
Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 44,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author : Ellen Agler,Mojie Crigler
Publisher : Johns Hopkins University Press
Page : 235 pages
File Size : 41,5 Mb
Release : 2019-01-15
Category : Medical
ISBN : 9781421427232
With a foreword by Bill Gates, this book fascinates, inspires, and gives readers concrete steps for further engagement.
Author : Anonim
Publisher : BoD – Books on Demand
Page : 166 pages
File Size : 54,6 Mb
Release : 2019-12-04
Category : Medical
ISBN : 9781789238891
Neglected tropical diseases (NTDs) is a diverse group of communicable diseases that prevail in tropical and subtropical conditions in 149 countries. NTDs affect more than one billion people and cost developing economies billions of dollars every year. According to the World Health Organization (WHO), NTDs mainly affect populations living in poverty, without adequate sanitation, and in close contact with infectious vectors, domestic animals, and livestock. Migration, as well as climate change and variability, are key factors in NTD prevalence. Therefore, NTDs deserve more study. Recently, viruses transmitted by vectors (arboviruses) that affect not only people living in the tropics, but also travelers and migrating populations, have been causing epidemics. Examples of these viruses include Dengue, Chikungunya, Zika, Mayaro, and encephalitis viruses. These viruses emerge and reemerge in multiple regions of the world, as occurred in the Americas recently (2013-2017) with Chikungunya and Zika. This book aims to update the significant epidemiological and clinical research of NTDs in many aspects with a multinational perspective.
Author : World Health Organization,World Health Organization. Department of Control of Neglected Tropical Diseases
Publisher : Unknown
Page : 0 pages
File Size : 46,5 Mb
Release : 2018-02-06
Category : Medical
ISBN : 9241565446
This report evaluates the changing global public health landscape; assesses progress towards the 2020 targets; and considers the possible core elements of a strategic vision to integrating neglected tropical diseases into the 2030 Agenda of the Sustainable Development Goals. Advances have been made through expanded interventions delivered through five public health approaches: innovative and intensified disease management; preventive chemotherapy; vector ecology and management; veterinary public health services; and the provision of safe water, sanitation and hygiene. In 2015 alone nearly one billion people were treated for at least one disease and significant gains were achieved in relieving the symptoms and consequences of diseases for which effective tools are scarce; important reductions were achieved in the number of new cases of sleeping sickness, of visceral leishmaniasis in South-East Asia and also of Buruli ulcer. The report also considers vector control strategies and discusses the importance of the draft WHO Global Vector Control Response 2017-2030. It argues that veterinary public health requires a multifaceted approach across the human-animal interface as well as a multisectoral program of work to protect and improve the physical, mental and social well-being of humans, including veterinary, water, sanitation and hygiene. Integration of activities and interventions into broader health systems is crucial, and despite challenges, has the potential to accelerate progress towards universal health coverage while advancing the 2030 Agenda. In short, this report drives the message home that "no one must be left behind."
Author : World Health Organization
Publisher : World Health Organization
Page : 112 pages
File Size : 43,9 Mb
Release : 2022-06-07
Category : Medical
ISBN : 9789240051423
Author : World Health Organization
Publisher : World Health Organization
Page : 82 pages
File Size : 45,5 Mb
Release : 2023-01-30
Category : Medical
ISBN : 9789240067295
The Global report on neglected tropical diseases 2023 provides a consolidated, up-to-date assessment of progress towards control, elimination and eradication of 20 diseases and disease groups (NTDs) globally, regionally and nationally. Progress is reported in the context of global commitments, strategies and targets set in the NTD road map 2021-2030. The document covers the first two years of implementation of the road map (2021 and 2022). The information presented is based primarily on epidemiological and programmatic data for interventions conducted in 2021 and gathered in 2022, but the report also describes a wide range of activities and accomplishments that were registered in both 2021 and 2022; comparisons are often made against 2020 and 2019 data, especially with regard to COVID-19 disruptions. It has four sections: Section 1 is an introduction. Section 2 presents the status of the global NTD response. Section 3 charts progress and developments against the three road map pillars. Section 4 sets out priority actions for 2023 and beyond to sustain implementation of the road map and its companion documents. Five annexes to the report provide information for 2021–2022 on regional progress (Annex 1), Weekly Epidemiology Record articles on NTDs (Annex 2), progress and challenges by disease (Annex 3), diagnostic target product profiles (Annex 4) and the status of commitments for donated medicines and health products (Annex 5).
Author : Goutam Brahmachari
Publisher : Elsevier
Page : 458 pages
File Size : 42,6 Mb
Release : 2019-04-15
Category : Medical
ISBN : 9780128157244
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more. In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases. Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Author : Claire J Standley,Jennifer K Peterson,Jared S Bakuza
Publisher : Mdpi AG
Page : 160 pages
File Size : 47,5 Mb
Release : 2021-08-18
Category : Health & Fitness
ISBN : 3036502866
"One Health" is defined as an approach to achieve better health outcomes for humans, animals, and the environment through collaborative and interdisciplinary efforts. The One Health framework is increasingly being applied to the management, control, and even elimination of neglected tropical diseases (NTDs), a set of infectious diseases that, collectively, affect more than one billion people across almost 150 countries. NTDs are some of the most common infections in the world; they cause substantial morbidity and mortality, particularly in regions with little access to medical care and other resources. Although there is increasing recognition of the major public health threat presented by NTDs, the ecological complexities of their transmission continue to pose challenges for their control and elimination. Some NTDs are zoonotic, meaning that they can be transmitted between humans and animals and, as such, present obstacles for public health and veterinary services in addition to concerns for wildlife conservation. Vector-borne NTDs necessitate measures that integrate consideration of the environment into public health strategies in order to sustainably reduce disease transmission. This book presents a collection of papers that explore various aspects of how the One Health concept is being applied to NTD control around the world, from genomics and diagnostic tools to improved surveillance and disease management. Encompassing research from Central America, the Caribbean, Asia, and sub-Saharan Africa, the collection emphasizes the diversity of NTDs as well as the critical importance of multisectoral collaboration for their control and elimination.