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Small-Animal SPECT Imaging by Matthew A. Kupinski,Harrison H. Barrett Pdf
Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.
George C. Kagadis,Nancy L. Ford,Dimitrios N. Karnabatidis,George K. Loudos
Author : George C. Kagadis,Nancy L. Ford,Dimitrios N. Karnabatidis,George K. Loudos Publisher : CRC Press Page : 1080 pages File Size : 53,6 Mb Release : 2018-09-03 Category : Medical ISBN : 9781315360423
Handbook of Small Animal Imaging by George C. Kagadis,Nancy L. Ford,Dimitrios N. Karnabatidis,George K. Loudos Pdf
The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.
Small Animal Imaging by Fabian Kiessling,Bernd J. Pichler,Peter Hauff Pdf
This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Small Animal Imaging by Fabian Kiessling,Bernd J. Pichler Pdf
Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study planning, animal handling, and the cost-effective performance of small animal imaging. Cross-calibration methods, data postprocessing, and special imaging applications are also considered in depth. This is the first book to cover all the practical basics in small animal imaging, and it will prove an invaluable aid for researchers, students, and technicians.
Molecular Imaging of Small Animals by Habib Zaidi Pdf
This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.
Emission Tomography by Miles N. Wernick,John N. Aarsvold Pdf
PET and SPECT are two of today’s most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world’s fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging. *Contains thorough tutorial treatments, coupled with coverage of advanced topics *Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors *Include color artwork
Physics of PET and SPECT Imaging by Magnus Dahlbom Pdf
PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitative techniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.
Small Animal Imaging by John S. Mattoon,Dana Neelis Pdf
Presented in an easy-to-ready format, Small Animal Imaging: Self-Assessment Color Review offers a case-based approach to reviewing and interpreting images and developing a differential diagnosis when necessary. Each case begins with the patient’s age, gender, breed, and species. The reason the patient was brought to the clinic is discussed along with preliminary examination and diagnostic test findings. The book Covers nearly 200 cases with supporting high-quality images for each case Provides detailed answers for each case, including radiographic findings and diagnosis Is written by well-respected experts in the field. A separate section presents detailed answers for each case including information on the radiographic findings. Also included are the radiographic diagnosis, comments, and notes on whether further imaging or evaluation is needed. This guide helps practitioners to develop a systematic approach to reviewing images. The easily-navigable text reminds practitioners of the basics in radiography and ultrasound interpretation and diagnosis, making it a quick and convenient reference.
Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Author : Patrick R. Gavin,Rodney S. Bagley Publisher : John Wiley & Sons Page : 390 pages File Size : 53,7 Mb Release : 2011-11-16 Category : Medical ISBN : 9781119949404
Practical Small Animal MRI by Patrick R. Gavin,Rodney S. Bagley Pdf
Dieses wegweisende Referenzwerk richtet sich an Veterinäre in Tierkliniken, die die Magnetresonanztomographie bei der Diagnose und Behandlung von Kleintieren einsetzen, und behandelt umfassend das Nervensystem, einschließlich Erkrankungen des Gehirns und der Wirbelsäule wie Entzündungen und Infektionen, Neoplasmien, Venenerkrankungen, angeborene und degenerative Krankheitsbilder. Einzelne Kapitel beschäftigen sich mit orthopädischen Problemen, Erkrankungen des Kopfes und des Nackens (u. a. Nasenhöhle, Ohr) und beschreiben Untersuchungsmethoden von Thorax und Abdomen. Grundlagen zum bildgebenden MRI-Verfahren werden ebenso vermittelt wie die Auswahl der richtigen Geräte.
Atlas of Small Animal Diagnostic Imaging by Clifford R. Berry,Nathan Nelson,Matthew D. Winter Pdf
ATLAS OF Small Animal Diagnostic Imaging Comprehensive and up-to-date resource on the interpretation of diagnostic images in small animals using survey radiographs and other modalities Atlas of Small Animal Diagnostic Imaging provides a comprehensive, multimodality atlas of small animal diagnostic imaging, with high-quality images depicting radiography, scintigraphy, ultrasonography, computed tomography, and magnetic resonance imaging. Taking a traditional body systems approach, the book offers an image-intensive resource to survey radiographs with some other imaging modalities being used to emphasize interpretation of survey radiographs. The Atlas offers clinically relevant information for small animal practitioners and students. Each body structure is thoroughly covered and well-illustrated, with discussion of the strengths and weaknesses of each modality in various scenarios. Edited by three experienced radiographers, The Atlas of Small Animal Diagnostic Imaging contains information on: Basics of diagnostic imaging, physics of diagnostic imaging, CT and MRI physics, US physics, and nuclear medicine physics Musculoskeletal normal anatomic variants, developmental orthopedic disease, joint disease, fracture and fracture healing, aggressive bone disease, and head and spine imaging Thorax anatomy, variants, and interpretation paradigm, extrathoracic structures, pleural space, pulmonary parenchyma, and mediastinum Abdomen anatomy, variants, and interpretation paradigm, extra-abdominal and body wall, peritoneal and retroperitoneal, liver and biliary, and spleen With its expansive coverage of the subject and hundreds of high-quality images to aid in efficient and seamless reader comprehension, Atlas of Small Animal Diagnostic Imaging is an invaluable and must-have resource for small animal practitioners, veterinary students, veterinary radiologists, and specialists in a number of areas.
Diagnostic Ultrasound in Small Animal Practice by Paddy Mannion Pdf
This new version of Frances Barr’s classic introductory text, Diagnostic Ultrasound in the Dog and Cat, has now been revised and expanded to cover the considerable technological and knowledge based advances since the first book was published in 1990. With contributions from leading subject experts, this new book covers both the theoretical principles behind the use of ultrasound in small animal practice and the practical approach to image interpretation. In-keeping with the user-friendly style of Frances Barr’s book, the book is extensively illustrated with photographs and accompanying line drawings. Organised around body systems, each chapter covers imaging procedures, normal appearances, abnormal appearances/diseases and specific conditions. Exotic animals, such as rabbits and reptiles are also included, as are new Doppler techniques. This practical guide is essential reading for all those involved in small animal imaging.
Handbook of Particle Detection and Imaging by Claus Grupen,Irène Buvat Pdf
The handbook centers on detection techniques in the field of particle physics, medical imaging and related subjects. It is structured into three parts. The first one is dealing with basic ideas of particle detectors, followed by applications of these devices in high energy physics and other fields. In the last part the large field of medical imaging using similar detection techniques is described. The different chapters of the book are written by world experts in their field. Clear instructions on the detection techniques and principles in terms of relevant operation parameters for scientists and graduate students are given.Detailed tables and diagrams will make this a very useful handbook for the application of these techniques in many different fields like physics, medicine, biology and other areas of natural science.
Author : Gustav Konrad von Schulthess Publisher : Lippincott Williams & Wilkins Page : 652 pages File Size : 48,5 Mb Release : 2007 Category : Medical ISBN : 0781776740
Molecular Anatomic Imaging by Gustav Konrad von Schulthess Pdf
This fully updated Second Edition focuses sharply on clinical PET-CT and SPECT-CT examinations, omitting lengthy physics discussions. The book is now strictly disease oriented and integrates PET-CT and SPECT-CT applications completely. When both techniques are relevant for a disease, they are discussed together; when only one is relevant, it is discussed alone. More than 1,200 illustrations are included. A bound-in DVD contains over 80 cases to be viewed in three orthogonal planes and different CT windows organized as reference and self-assessment files. The cases provide excellent training and allow readers to test their abilities in making diagnoses on their own.
