Soft Tissue Sarcomas Present Achievements And Future Prospects

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Soft Tissue Sarcomas: Present Achievements and Future Prospects

J. Verweij,H.M. Pinedo,H.D. Suit
Soft Tissue Sarcomas Present Achievements and Future Prospects Book PDF

Author : J. Verweij,H.M. Pinedo,H.D. Suit
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 54,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461561217

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Soft Tissue Sarcomas: Present Achievements and Future Prospects by J. Verweij,H.M. Pinedo,H.D. Suit Pdf

The previous volumes in this series on soft tissue sarcomas highlighted the importance of the multidisciplinary approach to treatment, and this focus is continued in the present volume. Proper diagnosis and staging remain the cornerstone of the treatment strategy. Sophisticated histopathology tech niques and growing consensus on grading systems have further increased the importance of the histopathologist in providing estimates of patient prognosis as well as in providing data for planning the treatment strategy. The use of cytogenetics in this field is rapidly increasing and might enable the distinction of subgroups in specific histological tumor types. Furthermore, molecular biological studies not only help reveal inherited predispositions and details in tumor oncogenesis, but they may also provide additional predictive factors for tumor behavior. Further data on treatment strategy will be provided by diag nostic imaging, and in this volume the value of PET imaging, a relatively new achievement, is highlighted. As far as the actual treatment is concerned, surgery still provides the major opportunity for cure. The addition of radiotherapy to surgery is of utmost importance in efforts to spare as much tissue as possible. The chapters on the planning of radiotherapy, brachytherapy, and the treatment of benign soft tissue lesions using radiotherapy are new contributions to this book. One of the potential late problems of radiotherapy is the occurrence of secondary soft tissue sarcomas, which is discussed in Chapter 10.

Targeting Treatment of Soft Tissue Sarcomas

Jaap Verweij,H.M. Pinedo
Targeting Treatment of Soft Tissue Sarcomas Book PDF

Author : Jaap Verweij,H.M. Pinedo
Publisher : Springer Science & Business Media
Page : 185 pages
File Size : 49,8 Mb
Release : 2004-05-27
Category : Medical
ISBN : 9781402078088

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Targeting Treatment of Soft Tissue Sarcomas by Jaap Verweij,H.M. Pinedo Pdf

- Discusses the latest drug treatments in the field - Gleevec arranged a bulk sale for this title - Written by leaders in the industry

Musculoskeletal Cancer Surgery

Martin M. Malawer,Paul H. Sugarbaker
Musculoskeletal Cancer Surgery Book PDF

Author : Martin M. Malawer,Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 626 pages
File Size : 55,7 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306484070

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Musculoskeletal Cancer Surgery by Martin M. Malawer,Paul H. Sugarbaker Pdf

Steven A. Rosenberg, MD In the past two decades significant progress has quality of life. The use of local radiation therapy has occurred, in the management of patients with mus- had a profound impact on the ability to achieve local loskeletal cancers, that has improved both the survival control. Cooperation between surgeons and radiation and the quality of life of afflicted patients. Changes in therapists often results in the tailoring of surgical p- the management of these patients have mirrored cedures to maximize the combined application of these trends in the entire field of oncology. two effective treatment modalities. Although impact on The most significant change has been improvement overall survival has not been demonstrated due to the in the surgical techniques for the resection of musculo- addition of radiation therapy, important advances in skeletal cancers based on a detailed understanding of improving the quality of life of patients receiving this the anatomic features of each particular tumor site, as combined-modality treatment have been evident. well as an appreciation of the natural biology that affects A third change impacting on the survival of patients the local spread of these tumors. The current volume of with musculoskeletal cancers has been the aggressive Musculoskeletal Cancer Surgery: Treatment of Sarcomas and resection of metastatic deposits.

Pediatric Radiation Oncology

Louis S. Constine,Nancy J. Tarbell,Edward C. Halperin
Pediatric Radiation Oncology Book PDF

Author : Louis S. Constine,Nancy J. Tarbell,Edward C. Halperin
Publisher : Lippincott Williams & Wilkins
Page : 512 pages
File Size : 41,9 Mb
Release : 2016-07-05
Category : Medical
ISBN : 9781496365682

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Pediatric Radiation Oncology by Louis S. Constine,Nancy J. Tarbell,Edward C. Halperin Pdf

Pediatric Radiation Oncology, Sixth Edition continues to be the premier reference that offers comprehensive coverage of this challenging area for the radiation oncologist in training or practice, medical radiation physicists and dosimetrists, as well as pediatric oncologists and others interested in understanding childhood malignancies. This definitive text has been completely updated to reflect recent advances in the field. Manageable in size and engaging to read, it efficiently synthesizes data on pathogenesis, pathology, diagnostic workup, staging, treatment approaches (particularly radiation therapy—indications, doses, volumes, and treatment planning), and toxic outcomes, as well as guidance on decision making when data is lacking. For 30 years, this standard reference has helped demystify radiation therapy for childhood cancer and contributed to the quality and quantity of life for children affected by this disease.

Pathology of Incipient Neoplasia

Donald Earl Henson,Jorge Albores-Saavedra
Pathology of Incipient Neoplasia Book PDF

Author : Donald Earl Henson,Jorge Albores-Saavedra
Publisher : Oxford University Press
Page : 868 pages
File Size : 47,9 Mb
Release : 2001-01-25
Category : Medical
ISBN : 0199771723

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Pathology of Incipient Neoplasia by Donald Earl Henson,Jorge Albores-Saavedra Pdf

Many malignant tumors have a morphologically recognizable precursor lesion. As screening and early detection have improved our ability to detect lesions at increasingly earlier stages of growth, an increased number of precancerous lesions are seen by pathologists. Unfortunately, a lack of uniform histologic criteria for precursors found in many organs can make diagnostic interpretation difficult. It is evident that physicians are seeking a better understanding of the genesis and progression of these lesions and their early biology, to provide optimal treatment and patient care. Pathology of Incipient Neoplasia 3E brings together all of the information available on the clinicopathologic features of precancerous lesions, defined to include atypical hyperplasias, in-situ changes, microinvasive or very small cancers in some sites, and other lesions recognized as potential precursors for invasive cancer. In some tissues, benign tumors may serve as precursors to malignant tumors, and therefore these also are considered. Organized by organ, each heavily-illustrated chapter is written by a well-recognized expert, to stress different facets of preneoplasia and minimally invasive tumors in that given tissue. Areas where strides have been made in research on molecular biologic aspects of neoplasia are discussed in conjunction with morphologic parameters. A chapter on salivary glands, and more than 350 color photos interspersed throughout the text, are new to this edition.

Cancer Metastasis and the Lymphovascular System:

Stanley P. L. Leong
Cancer Metastasis and the Lymphovascular System Book PDF

Author : Stanley P. L. Leong
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 55,9 Mb
Release : 2007-09-05
Category : Medical
ISBN : 9780387692197

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Cancer Metastasis and the Lymphovascular System: by Stanley P. L. Leong Pdf

This book details the anatomy and physiology of the lymphovascular system as well as describes the mechanisms of metastasis. It provides readers with an understanding of immune responses of draining lymph nodes against cancer. Coverage also explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis.

Cancer Informatics in the Post Genomic Era

Igor Jurisica,Dennis A. Wigle,Bill Wong
Cancer Informatics in the Post Genomic Era Book PDF

Author : Igor Jurisica,Dennis A. Wigle,Bill Wong
Publisher : Springer Science & Business Media
Page : 193 pages
File Size : 41,8 Mb
Release : 2007-05-04
Category : Medical
ISBN : 9780387693217

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Cancer Informatics in the Post Genomic Era by Igor Jurisica,Dennis A. Wigle,Bill Wong Pdf

Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.

Rare Hematological Malignancies

Stephen M. Ansell
Rare Hematological Malignancies Book PDF

Author : Stephen M. Ansell
Publisher : Springer Science & Business Media
Page : 435 pages
File Size : 42,7 Mb
Release : 2007-11-17
Category : Medical
ISBN : 9780387737447

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Rare Hematological Malignancies by Stephen M. Ansell Pdf

This hugely practical work will be a bible in the pocket of hematologists and other practitioners everywhere, covering as it does malignant hematologic diseases that physicians will only occasionally see. It provides accurate, up-to-date information on the disease biology as well as practical recommendations concerning disease management. Information concerning these diseases, and particularly regarding their management, can be extremely difficult to find. Not any more.

AIDS-Associated Viral Oncogenesis

Craig Meyers
AIDS Associated Viral Oncogenesis Book PDF

Author : Craig Meyers
Publisher : Springer Science & Business Media
Page : 274 pages
File Size : 41,8 Mb
Release : 2007-05-04
Category : Medical
ISBN : 9780387468167

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AIDS-Associated Viral Oncogenesis by Craig Meyers Pdf

One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

Cancer Clinical Trials: Proactive Strategies

Stanley P. L. Leong
Cancer Clinical Trials Proactive Strategies Book PDF

Author : Stanley P. L. Leong
Publisher : Springer Science & Business Media
Page : 326 pages
File Size : 48,8 Mb
Release : 2007-11-25
Category : Medical
ISBN : 9780387332253

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Cancer Clinical Trials: Proactive Strategies by Stanley P. L. Leong Pdf

Clinical trials remain the most important vehicle for improving the care of cancer patients. This text presents the fundamental components and challenges involving clinical investigations. Leading experts discuss the critical issues covering the spectrum of important topics from planning to application. The book has a foreword by Samuel A. Wells, Jr., MD, Professor of Surgery, Duke University Medical Center, Durham, NC, former Director of the American College of Surgeons and Founder of the American College of Surgeons Oncology Group.

Tumor Immunology and Cancer Vaccines

Samir Khleif
Tumor Immunology and Cancer Vaccines Book PDF

Author : Samir Khleif
Publisher : Springer Science & Business Media
Page : 388 pages
File Size : 50,7 Mb
Release : 2007-07-16
Category : Medical
ISBN : 9780387275451

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Tumor Immunology and Cancer Vaccines by Samir Khleif Pdf

- Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians - Text includes clinical trials - Written by leaders in the field

Radiation Toxicity: A Practical Medical Guide

William Small,Gayle E. Woloschak
Radiation Toxicity A Practical Medical Guide Book PDF

Author : William Small,Gayle E. Woloschak
Publisher : Springer Science & Business Media
Page : 187 pages
File Size : 51,6 Mb
Release : 2006-03-12
Category : Medical
ISBN : 9780387253541

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Radiation Toxicity: A Practical Medical Guide by William Small,Gayle E. Woloschak Pdf

Radiation Toxicity: A Practical Guide provides insight into the management of day-to-day aspects of radiotherapy. Most radiation oncologists and radiation oncology nurses spend a large percentage of their time dealing with the effects of radiotherapy. This book describes the biology behind each sites acute and long-term responses to radiotherapy, including the best current knowledge regarding radiation tolerance, and fills a needed void in the literature that is available on radiation oncology.

Cytokines and Cancer

Leonidas C. Platanias
Cytokines and Cancer Book PDF

Author : Leonidas C. Platanias
Publisher : Springer Science & Business Media
Page : 381 pages
File Size : 45,7 Mb
Release : 2006-05-06
Category : Medical
ISBN : 9780387243610

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Cytokines and Cancer by Leonidas C. Platanias Pdf

The first book to cover both basic science and clinical research, providing a comprehensive review of the current knowledge on cytokines and cancer. Written by leading figures in the field of cytokine biology and cytokine therapeutics.

Biological Basis of Geriatric Oncology

Lodovico Balducci,Martine Extermann
Biological Basis of Geriatric Oncology Book PDF

Author : Lodovico Balducci,Martine Extermann
Publisher : Springer Science & Business Media
Page : 256 pages
File Size : 53,9 Mb
Release : 2006-06-14
Category : Medical
ISBN : 9780387239620

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Biological Basis of Geriatric Oncology by Lodovico Balducci,Martine Extermann Pdf

This volume highlights research issues specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It conveys a sustainable way of thinking about cancer and aging.

The Link Between Inflammation and Cancer

Angus G. Dalgleish,Burkhard Haefner
The Link Between Inflammation and Cancer Book PDF

Author : Angus G. Dalgleish,Burkhard Haefner
Publisher : Springer Science & Business Media
Page : 260 pages
File Size : 49,9 Mb
Release : 2006-03-05
Category : Medical
ISBN : 9780387262833

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The Link Between Inflammation and Cancer by Angus G. Dalgleish,Burkhard Haefner Pdf

A link between inflammation and cancer has been established many years ago, yet it is only recently that the potential significance of this connection has become apparent. Although several examples of chronic inflammatory conditions, often induced by persistent irritation and/or infection, developing into cancer have been known for some time, there has been a notable resistance to contemplate the possibility that this association may apply in a causative way to other cancers. Examples for such progression from chronic inflammation to cancer are colon carcinoma developing with increased frequency in patients with ulcerative colitis, and the increased incidence of bladder cancer in patients suffering from chronic Schistosoma infection. Inflammation and cancer have been recognized to be linked in another context for many years, i.e., with regards to pathologies resembling chronic lacerations or 'wounds that do not heal.' More recently, the immunology of wound healing has given us clues as to the mechanistic link between inflammation and cancer, in as much as wounds and chronic inflammation turn off local cell-mediated immune responses and switch on growth factor release as well the growth of new blood vessels - angiogenesis. Both of these are features of most types of tumours, which suggest that tumours may require an immunologically shielded milieu and a growth factor-rich environment.