Stem Cell Dialogues

Author : Sheldon Krimsky
Publisher : Columbia University Press
Page : 280 pages
File Size : 44,8 Mb
Release : 2015-06-23
Category : Science
ISBN : 9780231539401

Get Book

Stem Cell Dialogues by Sheldon Krimsky Pdf

Stem cells and the emerging field of regenerative medicine are at the frontiers of modern medicine. These areas of scientific inquiry suggest that in the future, damaged tissue and organs might be repaired through personalized cell therapy as easily as the body repairs itself, revolutionizing the treatment of numerous diseases. Yet the use of stem cells is fraught with ethical and public policy dilemmas that challenge scientists, clinicians, the public health community, and people of good will everywhere. How shall we deal with these amazing biomedical advances, and how can we talk about potential breakthroughs with both moral and scientific intelligence? This book provides an innovative look at these vexing issues through a series of innovative Socratic dialogues that elucidate key scientific and ethical points in an approachable manner. Addressing the cultural and value issues underlying stem cell research while also educating readers about stem cells' biological function and medical applications, Stem Cell Dialogues features fictional characters engaging in compelling inquiry and debate. Participants investigate the scientific, political, and socioethical dimensions of stem cell science using actual language, analysis, and arguments taken from scientific, philosophical, and popular literature. Each dialogue centers on a specific, recognizable topic, such as the policies implemented by the George W. Bush administration restricting the use of embryonic stem cells; the potential role of stem cells in personalized medicine; the ethics of cloning; and the sale of eggs and embryos. Additionally, speakers debate the use of stem cells to treat paralysis, diabetes, stroke effects, macular degeneration, and cancer. Educational, entertaining, and rigorously researched (with 300 references to scientific literature), Stem Cell Dialogues should be included in any effort to help the public understand the science, ethics, and policy concerns of this promising field.

Author : Kristina Hug,Göran Hermerén
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 49,8 Mb
Release : 2010-12-25
Category : Science
ISBN : 9781607619598

Get Book

Translational Stem Cell Research by Kristina Hug,Göran Hermerén Pdf

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.

Author : Dov Zipori
Publisher : Springer Science & Business Media
Page : 295 pages
File Size : 43,9 Mb
Release : 2009-09-01
Category : Science
ISBN : 9781607611301

Get Book

Biology of Stem Cells and the Molecular Basis of the Stem State by Dov Zipori Pdf

Biology of Stem Cells and the Molecular Basis of the Stem State concentrates upon adult stem cells, particularly on mesenchymal cell populations, which is the author’s area of expertise. The text offers the reader a detailed description of the emergence of stem cell research and the dogmas that were created during the first decades of analysis of stem cell properties, particularly those of hemopoietic stem cells. Biology of Stem Cells and the Molecular Basis of the Stem State also introduces the reader to the commonly accepted notions regarding stem cell biology, with an emphasis on an alternative view of stemness, i.e. the stem state. In keeping with the popularity of this topic, Biology of Stem Cells and the Molecular Basis of the Stem State addresses the major controversies and points of dispute, among researchers in the stem cell field. Overall, Biology of Stem Cells and the Molecular Basis of the Stem State presents a well-rounded dialogue about stem cells as it not only concentrates upon the biological elements of stem cell, but also addresses the controversy and hype currently enveloping this popular subject.

Author : Kristina Hug,Göran Hermerén
Publisher : Humana Press
Page : 462 pages
File Size : 44,6 Mb
Release : 2011-07-21
Category : Science
ISBN : 1607619601

Get Book

Translational Stem Cell Research by Kristina Hug,Göran Hermerén Pdf

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. Translational Stem Cell Research is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma. Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.

Author : William Dudley
Publisher : Referencepoint Press
Page : 0 pages
File Size : 42,8 Mb
Release : 2014
Category : Human embryo
ISBN : 1601525869

Get Book

Thinking Critically by William Dudley Pdf

Human stem cells were have been known as a promising avenue for research and medicine since the late 1990s, but stem cell research had has been engulfed in controversy. Through a narrative-driven pro/con format¿supported by facts, quotes, anecdotes, and full-color illustrations¿this title examines issues related to stem cell research. Topics include: Is Embryonic Stem Cell Research Ethical? Is Embryonic Stem Cell Research Still Necessary? Should Government Place Restrictions on Stem Cell Research Funding? Should Government Closely Regulate Stem Cell Medical Treatments?

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publisher : National Academies Press
Page : 112 pages
File Size : 48,6 Mb
Release : 2002-01-25
Category : Science
ISBN : 9780309170420

Get Book

Stem Cells and the Future of Regenerative Medicine by Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research Pdf

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research
Publisher : National Academies Press
Page : 224 pages
File Size : 52,7 Mb
Release : 2005-09-15
Category : Medical
ISBN : 9780309096539

Get Book

Guidelines for Human Embryonic Stem Cell Research by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on Guidelines for Human Embryonic Stem Cell Research Pdf

Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Author : James T. Bradley
Publisher : University of Alabama Press
Page : 359 pages
File Size : 40,9 Mb
Release : 2013-04-02
Category : Medical
ISBN : 9780817317881

Get Book

Brutes Or Angels by James T. Bradley Pdf

"With stem cell research, Dolly the cloned sheep, in vitro fertilization, age retardation, and pharmaceutical mind enhancement, humankind is now faced with decisions that it has never before had to consider. The thoughtfulness, or lack of it, that we bring to those decisions will largely determine the future character of the living world. Brutes or Angels will facilitate informed choice making about the personal use of biotechnologies and the formulation of public policies governing their development and use. Ten biotechnologies that impact humans are considered: stem cell research, embryo selection, human genomics, gene therapies, human reproductive cloning, age retardation, cognition enhancement, the engineering of nonhuman organisms, nanobiology, and synthetic biology. With deft and assured use of metaphors, analogies, diagrams, and photographs, James T. Bradley introduces important biological principles and the basic procedures used in biotechnology. Various ethical issues--personhood, personal identity, privacy, ethnic discrimination, distributive justice, authenticity and human nature, and the significance of mortality in the human life cycle--are presented in a clear and unbiased manner. Personal reflection and group dialogue are encouraged by questions at the end of each chapter, making this book not only a general guide to better informed and nuanced thinking on these complex and challenging topics but also an appropriate text for bioethics courses in university science departments and for adult education classes." -- Publisher's description.

Author : M. Fagan
Publisher : Springer
Page : 274 pages
File Size : 41,9 Mb
Release : 2013-01-21
Category : Science
ISBN : 9781137296023

Get Book

Philosophy of Stem Cell Biology by M. Fagan Pdf

This examination of stem cell biology from a philosophy of science perspective clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. Relations to systems biology and clinical medicine are also discussed.

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Engineering, and Public Policy
Publisher : National Academies Press
Page : 295 pages
File Size : 53,9 Mb
Release : 2002-06-17
Category : Science
ISBN : 9780309076371

Get Book

Scientific and Medical Aspects of Human Reproductive Cloning by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs,Committee on Science, Engineering, and Public Policy Pdf

Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.

Author : Henry J. Leese,Daniel R. Brison
Publisher : Springer
Page : 216 pages
File Size : 53,9 Mb
Release : 2015-05-08
Category : Science
ISBN : 9781493924806

Get Book

Cell Signaling During Mammalian Early Embryo Development by Henry J. Leese,Daniel R. Brison Pdf

The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.

Author : Stuart Lane,Francisco Klauser,Matthew B. Kearnes
Publisher : John Wiley & Sons
Page : 257 pages
File Size : 52,9 Mb
Release : 2012-02-28
Category : Science
ISBN : 9781119945253

Get Book

Critical Risk Research by Stuart Lane,Francisco Klauser,Matthew B. Kearnes Pdf

Risk Research: Practices, Politics and Ethics offers a collection of essays, written by a wide variety of international researchers in risk research, about what it means to do risk research, and about how – and with what effects – risk research is practiced, articulated and exploited. This approach is based upon the core assumption that: to make a difference in the study of risk, we must move beyond what we usually do, challenging the core assumptions, scientific, economic and social, about how we study, frame, exploit and govern risk. Hence, through a series of essays, the book aims to challenge the current ways in which risk-problems are approached and presented, both conceptually by academics and through the framings that are encoded in the technologies and socio-political and institutional practices used to manage risk. In addressing these questions, the book does not attempt to offer a model of how risk research 'should' be done. Rather, the book provides, through illustration, a challenge to the ways in which risk research is framed as 'problem-solving.' The book's ultimate objective aims to increase critical debate between different disciplines, approaches, concepts and problems.

Author : Melville Y. Stewart
Publisher : John Wiley & Sons
Page : 1168 pages
File Size : 43,6 Mb
Release : 2009-12-01
Category : Philosophy
ISBN : 1444317369

Get Book

Science and Religion in Dialogue by Melville Y. Stewart Pdf

This two-volume collection of cutting edge thinking aboutscience and religion shows how scientific and religious practicesof inquiry can be viewed as logically compatible, complementary,and mutually supportive. Features submissions by world-leading scientists andphilosophers Discusses a wide range of hotly debated issues, including BigBang cosmology, evolution, intelligent design, dinosaurs andcreation, general and special theories of relativity, dark energy,the Multiverse Hypothesis, and Super String Theory Includes articles on stem cell research and Bioethics byWilliam Hurlbut, who served on President Bush's BioethicsCommittee

Author : Sarojini Henry
Publisher : ISPCK
Page : 242 pages
File Size : 54,6 Mb
Release : 2005
Category : Religion and science
ISBN : 817214878X

Get Book

The Encounter of Faith and Science in Inter-religious Dialogue by Sarojini Henry Pdf

Author : Anonim
Publisher : Unknown
Page : 146 pages
File Size : 48,8 Mb
Release : 1999
Category : Bioethics
ISBN : NYPL:33433020970533

Get Book

Ethical Issues in Human Stem Cell Research by Anonim Pdf