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Stereotactic Radiosurgery for Prostate Cancer by Michael J. Zelefsky Pdf
This book offers a comprehensive evaluation of the use of stereotactic body radiosurgery (SBRT) for the treatment of prostate cancer. The rationale, selection criteria, and treatment planning for prostate SBRT are explained. Important imaging and anatomic considerations are discussed, and detailed consideration devoted to organ motion and tumor tracking during SBRT. Outcomes of therapy are then examined, with thorough appraisal of side effect profiles and quality of life impacts. Clear guidance is provided on how to deliver the therapy in a way that minimizes the risk of long-term urinary and rectal toxicities. Stereotactic radiosurgery for prostate cancer is an increasingly used form of treatment. Retrospective investigations have demonstrated the safe application of high-dose treatments, with 5-year results comparable to those achieved with protracted external beam radiotherapy. Prospective studies are underway comparing SBRT with more traditional forms of image-guided and intensity-modulated radiotherapy. In offering in-depth guidance on safe delivery of prostate SBRT, this book will be of value for students of radiation oncology, more experienced practitioners, and medical physicists.
Stereotactic Radiosurgery for Prostate Cancer by Anonim Pdf
This book offers a comprehensive evaluation of the use of stereotactic body radiosurgery (SBRT) for the treatment of prostate cancer. The rationale, selection criteria, and treatment planning for prostate SBRT are explained. Important imaging and anatomic considerations are discussed, and detailed consideration devoted to organ motion and tumor tracking during SBRT. Outcomes of therapy are then examined, with thorough appraisal of side effect profiles and quality of life impacts. Clear guidance is provided on how to deliver the therapy in a way that minimizes the risk of long-term urinary and rectal toxicities. Stereotactic radiosurgery for prostate cancer is an increasingly used form of treatment. Retrospective investigations have demonstrated the safe application of high-dose treatments, with 5-year results comparable to those achieved with protracted external beam radiotherapy. Prospective studies are underway comparing SBRT with more traditional forms of image-guided and intensity-modulated radiotherapy. In offering in-depth guidance on safe delivery of prostate SBRT, this book will be of value for students of radiation oncology, more experienced practitioners, and medical physicists.
Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate by Dwight E. Heron,John Austin Vargo Pdf
Stereotactic radiosurgery is a relatively recent radiation technique initially developed using a frame-based system in 1949 by a Swedish neurosurgeon, Lars Leksell, for lesions not amendable to surgical resection. Radiosurgery is founded on principles of extreme radiation dose escalation, afforded by precise dose delivery with millimeter accuracy. Building upon the success of frame-based radiosurgery techniques, which were limited to cranial tumors and invasive head-frame placement, advances in radiation delivery and image-guidance have lead to the development of stereotactic body radiotherapy (SBRT). SBRT allows for frameless delivery of dose distributions akin to frame-based cranial stereotactic radiosurgery to both cranial and extra-cranial sites and has emerged as a important treatment strategy for a variety of cancers from the cranium to prostate. Herein we highlight ongoing investigations for the clinical application of SBRT for a variety of primary and recurrence cancers aimed at examining the growing clinical evidence supporting emerging roles for SBRT in the ever growing oncologic armamentarium.
Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) by Dwight E. Heron, MD, MBA, FACRO, FACR,M. Saiful Huq, PhD, DABR, FAAPM, FInstP,Joseph M. Herman, MD, MSc Pdf
Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy (SBRT) is a comprehensive guide for the practicing physician and medical physicist in the management of complex intracranial and extracranial disease. It is a state-of-the-science book presenting the scientific principles, clinical background and procedures, treatment planning, and treatment delivery of SRS and SBRT for the treatment of tumors throughout the body. This unique textbook is enhanced with supplemental video tutorials inclusive to the resource. Beginning with an overview of SRS and SBRT, Part I contains insightful coverage on topics such as the evolving radiobiological principles that govern treatment, imaging, the treatment planning process, technologies and equipment used, as well as focused chapters on quality assurance, quality management, and patient safety. Part II contains the clinical application of SRS and SBRT for tumors throughout the body including those in the brain, head and neck, lung, pancreas, adrenal glands, liver, prostate, cervix, spine, and in oligometastatic disease. Each clinical chapter includes an introduction to the disease site, followed by a thorough review of all indications and exclusion criteria, in addition to the important considerations for patient selection, treatment planning and delivery, and outcome evaluation. These chapters conclude with a detailed and site-specific dose constraints table for critical structures and their suggested dose limits. International experts on the science and clinical applications of these treatments have joined together to assemble this must-have book for clinicians, physicists, and other radiation therapy practitioners. It provides a team-based approach to SRS and SBRT coupled with case-based video tutorials in disease management, making this a unique companion for the busy radiosurgical team. Key Features: Highlights the principles of radiobiology and radiation physics underlying SRS and SBRT Presents and discusses the expected patient outcomes for each indicated disease site and condition including a detailed analysis of Quality of Life (QOL) and Survival Includes information about technologies used for the treatment of SRS and SBRT Richly illustrated with over 110 color images of the equipment, process flow diagrams and procedures, treatment planning techniques and dose distributions 7 high-quality videos reviewing anatomy, staging, treatment simulation and planning, contouring, and management pearls Dose constraint tables at the end of each clinical chapter listing critical structures and their appropriate dose limits Includes access to the fully-searchable downloadable eBook
Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter
Author : Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter Publisher : Springer Science & Business Media Page : 433 pages File Size : 44,5 Mb Release : 2012-08-28 Category : Medical ISBN : 9783642256042
Stereotactic Body Radiation Therapy by Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter Pdf
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter
Author : Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter Publisher : Springer Science & Business Media Page : 434 pages File Size : 41,6 Mb Release : 2012-08-28 Category : Medical ISBN : 9783642256059
Stereotactic Body Radiation Therapy by Simon S. Lo,Bin S. Teh,Jiade J. Lu,Tracey E. Schefter Pdf
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Stereotactic Body Radiotherapy by Andrew Gaya,Anand Mahadevan Pdf
This is a single, comprehensive handbook for clinical oncology trainees and consultants, covering the basic aspects of stereotactic radiotherapy systems and treatment.
Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy by Rajni A. Sethi,Igor J. Barani,David A. Larson,Mack Roach III Pdf
This handbook concisely summarizes state-of-the-art information about stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), including the history and development of these modalities, the biologic rationale for these technologies, typical practices, and reported results. Developed as a companion to Handbook of Evidence-Based Radiation Oncology, edited by Eric Hansen and Mack Roach, III, it is organized by disease site and presents treatment techniques and recommended imaging; safety and quality assurance; toxicities and management; recommended follow-up; and supporting evidence. Inclusion of evidence-based guidelines is intended to help inform decisions regarding the appropriateness of SRS and SBRT and guide treatment and evaluation. This new edition is fully updated with the latest literature. A new chapter on dose constraints has also been added, along with additional content on SBRT for oligometastatic disease and prostate, and the integration of SBRT with systemic therapy, including chemotherapy, immunotherapy, targeted agents. Case examples are added, as well as additional images to highlight situations described. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy, 2e can be easily referenced in the clinic and is a valuable guide for radiation oncology practitioners
Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma
Author : Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma Publisher : Springer Science & Business Media Page : 245 pages File Size : 50,6 Mb Release : 2011-11-19 Category : Medical ISBN : 3642114954
Robotic Radiosurgery Treating Prostate Cancer and Related Genitourinary Applications by Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma Pdf
The treatment of prostate cancer continues to be problematic owing to serious side-effects, including erectile dysfunction and urinary incontinence. Robotic radiosurgery offers a novel, rapid, non-invasive outpatient treatment option that combines robotics, advanced image-guided spatial positioning, and motion detection with submillimeter precision. This book examines all aspects of the treatment of prostate cancer with robotic radiosurgery. It explains how image-guided robotic radiosurgery overcomes the problem of patient motion during radiation therapy by continuously identifying the precise location of the prostate tumor throughout the course of treatment. Hypofractionated radiation delivery by means of robotic radiosurgery systems is also discussed in detail. The book closes by examining other emerging genitourinary applications of robotic radiosurgery. All of the authors are experts in their field who present a persuasive case for this fascinating technique.
Hypofractionated and Stereotactic Radiation Therapy by Orit Kaidar-Person,Ronald Chen Pdf
This handbook summarizes the data and techniques for hypofractionation and stereotactic radiation in a clinically-accessible way. Hypofractionated radiation therapy, which consists of larger-dose radiation treatments that are given over a shorter time period compared to conventional radiation fraction sizes, is used to treat a variety of cancers, including prostate, breast, lung, and colorectal. Conventional radiation therapy and hypofractionated radiation therapy have different effectiveness rates for cancer treatment and have different impacts on normal tissues in terms of causing toxicity. There is a significant and growing body of literature on the use of different dosing regimens to treat a variety of cancers and radiation oncologists need to keep up with the various dosing schedules, the effect of each regimen on cancer control in different cancers, and how the different schedules affect each organ in terms of toxicity. The book thus provides concise information ranging from commonly-used dose-fractionation schemes for hypofractionated and stereotactic body radiotherapy to simulation and treatment specifications to published safety and efficacy data. Chapters additionally examine the biological rationales for the efficacy of hypofractionated radiation; present clinical studies that demonstrate the efficacy and safety of hypofractionated radiation treatment in a variety of cancers; and describe the advances in technology that have allowed hypofractionated radiation to be safely given. This is an ideal guide for radiation oncology clinicians and trainees.
Thomas Bortfeld,Rupert Schmidt-Ullrich,Wilfried De Neve,David E. Wazer
Author : Thomas Bortfeld,Rupert Schmidt-Ullrich,Wilfried De Neve,David E. Wazer Publisher : Springer Science & Business Media Page : 452 pages File Size : 46,6 Mb Release : 2006-05-28 Category : Medical ISBN : 9783540303565
Image-Guided IMRT by Thomas Bortfeld,Rupert Schmidt-Ullrich,Wilfried De Neve,David E. Wazer Pdf
Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.
This issue of Radiation Medicine Rounds examines the latest advances in the use of radiation medicine in treatment of prostate cancer Prostate cancer is the most common cancer in males and radiation therapy is a major tool in the management of the disease. This issue of Radiation Medicine Rounds includes reviews of all major recent advances in treatment of favorable, intermediate and high-risk prostate cancer as well as newer modalities such as brachytherapy, stereotactic body radiation therapy, and proton beam radiotherapy. Articles also review current knowledge in the areas of new biomarkers, risk stratification, and risk stratification. This issue of RMR will provide the practitioner with a full current overview of the present best practices and recent research in management of this complex and challenging disease. Radiation Medicine Rounds features: In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Radiation Medicine Each issue edited by an authority in that subject area Each issue focused on a single major topic in Radiation Medicine, providing coverage of advances in radiation science, radiation medicine technology, radiation medicine practice, and assessment of recent quality and outcome studies
Spine Radiosurgery by Peter Gerszten,Samuel Ryu Pdf
Spine Radiosurgery, Second Edition , is a comprehensive text that includes discussions of the latest devices, treatment planning techniques, target definition, and patient selection in this specialty. Written by leading experts in the fields of neurosurgery, radiation oncology, and medical physics, this book is the definitive reference for clinical applications of state-of-the-art radiosurgery of the spine. Key Features: Six new chapters on such topics as histopathological examination of spinal lesions, minimally invasive techniques, and treatment of spinal chordomas More than 100 full-color illustrations demonstrate key concepts Discussion of new treatments for metastatic spine disease and spinal cord compression This book is a must-have resource for clinicians, fellows, and residents in neurosurgery and radiation oncology. Spine surgeons, orthopaedists, medical physicists, and oncologists at all levels will also benefit from the wealth of information provided.
Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma
Author : Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma Publisher : Springer Page : 0 pages File Size : 43,8 Mb Release : 2011-11-23 Category : Medical ISBN : 3642114946
Robotic Radiosurgery Treating Prostate Cancer and Related Genitourinary Applications by Lee E. Ponsky,Donald B. Fuller,Robert M. Meier,Charlie Ma Pdf
The treatment of prostate cancer continues to be problematic owing to serious side-effects, including erectile dysfunction and urinary incontinence. Robotic radiosurgery offers a novel, rapid, non-invasive outpatient treatment option that combines robotics, advanced image-guided spatial positioning, and motion detection with submillimeter precision. This book examines all aspects of the treatment of prostate cancer with robotic radiosurgery. It explains how image-guided robotic radiosurgery overcomes the problem of patient motion during radiation therapy by continuously identifying the precise location of the prostate tumor throughout the course of treatment. Hypofractionated radiation delivery by means of robotic radiosurgery systems is also discussed in detail. The book closes by examining other emerging genitourinary applications of robotic radiosurgery. All of the authors are experts in their field who present a persuasive case for this fascinating technique.