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Author : Brigitte Kaissling
Publisher : Unknown
Page : 0 pages
File Size : 46,6 Mb
Release : 1979
Category : Anatomy
ISBN : OCLC:489926835
Author : Brigitte Kaissling,W. Kriz
Publisher : Springer
Page : 126 pages
File Size : 47,9 Mb
Release : 1979-01-01
Category : Science
ISBN : 3540091459
Karl Peter stated in 1909 in his famous monograph, Untersuchungen iiber Bau und Entwicklung der Niere, that the rabbit has a simply structured kidney and without knowledge of it he would not have succeeded in understanding the structural organi zation of other more complicated kidneys. Even with today's advanced knowledge of kidney organization this statement is still valid. With regard to the histotopographic relations of tubules and vessels as well as to the ultrastructure, the rabbit kidney is more simply organized than other mammalian kidneys, for example the mouse kidney and especially the Psammomys kidney. The rabbit kidney essentially displays the basic pattern of a mammalian kidney. Therefore, a thorough knowledge of the morphology of the rabbit kidney is indispensable for investigating kidneys of other species. Another reason for extensively investigating the rabbit kidney is that it is the only kidney with tubules that can easily be isolated and, therefore, be used for in vitro experiments (Burg et al. , 1966). Many investigations using these techniques have been performed in the last decade (for references see corresponding chapters). Accordingly the different segments of the nephron are functionally best characterized in the rabbit kidney. The purpose of this paper is to supply the basis for good structural-functional correlations. 2 Material and Methods 2. 1 Light Microscopy The histologic and histotopographic observations are based on a study of the kidneys of a total of 25 male and female New Zealand rabbits (2500-4500 g body wt. ). . 2. 1.
Author : Mark A. Suckow,Karla A. Stevens,Ronald P. Wilson
Publisher : Academic Press
Page : 1289 pages
File Size : 51,7 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9780123809209
This is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well illustrated reference includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. It is a resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu Includes up-to-date, common experimental methods. Organized by species for easy access during bench research.
Author : Esmail Koushanpour,Wilhelm Kriz
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 44,5 Mb
Release : 2013-03-14
Category : Medical
ISBN : 9781475719123
The first edition of this book was well received by updated. The two of us have made further collab orative efforts to present a better understanding of medical students, graduate students, and clinicians interested in furthering their understanding of basic the function of the kidney in conjunction with the principles of renal physiology. Most of the reviews most recent anatomical findings. of the first edition and comments from the various The second edition consists of 13 Chapters and 3 instructors who used the book were very positive Appendices. As in the first edition, the anatomical and complimentary with regard to the presentation description of the kidney is incorporated into the of the physiological information and the use of the various chapters dealing with kidney functions. Most system analysis approach to describe renal function. of the anatomical information was written by Wil These positive and encouraging comments over the helm Kriz. The physiological information was writ past nine years, since the publication of the first ten by Esmail Koushanpour, except for Chapter 12 edition, gave us the impetus to consider the prepa which was jointly written. Chapters 1 through 3 were ration of a second edition.
Author : Robert J. Alpern,Steven C. Hebert
Publisher : Elsevier
Page : 2928 pages
File Size : 54,6 Mb
Release : 2007-10-10
Category : Science
ISBN : 9780080559506
A classic nephrology reference for over 20 years, Seldin & Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch’s The Kidney is your number one source for information. * Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic. * Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics. * Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.
Author : Anonim
Publisher : Unknown
Page : 574 pages
File Size : 51,7 Mb
Release : 1979
Category : Kidneys
ISBN : RUTGERS:39030039664521
Author : Thomas C. Jones,Gordon C. Hard,Ulrich Mohr
Publisher : Springer Science & Business Media
Page : 496 pages
File Size : 42,6 Mb
Release : 2013-03-12
Category : Medical
ISBN : 9783642803352
A complete update on the safety testing of foods, drugs, and chemicals in laboratory animals, featuring: - a thorough review of each subject area with extensive revision in line with new information and concepts - electron micrographs in exquisite detail to illustrate results of recent research - the effects of many carcinogens described succinctly and illustrated in detail - neoplasms described in detail and compared with natural and induced tumours in other species - standardised nomenclature. Of interest to those interested in the many applications to human patients, Urinary System: - facilitates uniform interpretation of bioassay results world-wide - provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures of the kidneys - explains the functional significance of details by identifying the composition of structures at the molecular level. Forming a solid basis for understanding the causes and effects of disease of the urinary system, this is essential reading for pathologists, toxicologists, regulatory agencies, and all those involved in carcinogenicity and toxicity studies.
Author : Anonim
Publisher : Academic Press
Page : 491 pages
File Size : 55,7 Mb
Release : 1987-06-04
Category : Science
ISBN : 0080584993
Current Topics in Membranes and Transport
Author : Michinobu Hatano
Publisher : Springer
Page : 1749 pages
File Size : 40,6 Mb
Release : 2013-12-01
Category : Medical
ISBN : 9783662351581
Author : J. Charles Jennette
Publisher : Lippincott Williams & Wilkins
Page : 930 pages
File Size : 51,8 Mb
Release : 2007
Category : Medical
ISBN : 0781747503
Experts in the field of renal disease offer careful pathologic descriptions, appropriate clinical correlations, and extensive discussions on causes and pathogenesis to clarify the clinicians understanding and help facilitate easy, accurate diagnosis. This updated edition features hundreds of razor-sharp illustrations along with more international contributors than before.
Author : Thomas E. Andreoli,Darrell D. Fanestil,Joseph F. Hoffman,Stanley G. Schultz
Publisher : Springer Science & Business Media
Page : 1062 pages
File Size : 53,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781461320975
The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition . Yet the purpose ofthe second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably. THE EDITORS xi Preface to the First Edition The purpose of this book is to provide the reader with a rational frame of reference for assessing the pa thophysiology of those disorders in which derangements of membrane transport processes are a major factor responsible for the clinical manifestations of disease. In the present context, we use the term "membrane transport to refer to those molecular processes whose cardinal function, broadly speaking, is processes" in a catholic sense, the vectorial transfer of molecules-either individually or as ensembles-across biological interfaces, the latter including those interfaces which separate different intracellular compartments, the cellular and extracellular com partments, and secreted fluids-such as glomerular filtrate-and extracellular fluids.
Author : Thomas E. Andreoli,Darrell D. Fanestil,Joseph F. Hoffman,Stanley G. Schultz
Publisher : Springer Science & Business Media
Page : 399 pages
File Size : 45,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468454048
Membrane Transport Processes in Organized Systems is a softcover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the fourth and fifth sections: Transport Events in Single Cells and Transport in Epithelia: Vectorial Transport through Parallel Arrays. We hope that this smaller volume, which deals with transport processes in single cells and in organized epithelia, will be helpful to individuals interested in general physiology, transport in single cells and epithelia, and the methods for studying those transport processes. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ Vll Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion ofthe first edition . Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes play a cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.
Author : Michael Dunn
Publisher : Springer Science & Business Media
Page : 406 pages
File Size : 40,9 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781468442779
In June, 1981, we conducted a two day international symposium in Rome devoted to original scientific presentations on arachidonic acid metabolism in the kidney. Scientists from 20 countries were represented either in the general scientific program or in the poster presentation. This book does not represent the proceedings of this international gathering, but rather the edited manuscripts specifically prepared as sum maries of the scientific presentations. We feel that the timeliness and originality of the contributions as well as the need for a compilation of existing work on prosta glandins, thromboxane, and the kidney warrant this publication. The meetings would have been impossible without the generous and substantial support of the Italian government, the National Institutes of Health, United States Public Health Service, and Merck Sharp & Dohme International. Supplementary support was also received from Ciba Geigy S. p. A., Ente Fiuggi, Farmitalia Carlo Erba S. p. A., Glaxo Laboratori S. p. A., Hoechst Italia S. p. A., Leo Pharmaceutical Products, Pfizer Italiana S. p. A., Sigm? Tau S. p. A., Squibb S. p. A., The Upjohn Company, Wellcome Italia S. p. A., and Burroughs Wellcome Company. The efficient organization of the symposium was largely attributable to the superb efforts of Elisabeth Mutschlechner and Miki Scarinci of C.K. International, Rome. Linda Goldberg provided expert and invaluable editorial and secretarial assistance in the organization of this book. The book is divided into four major sections comprising: I.
Author : Ferdinand Rodriguez,Ferdinand Cohen,Christopher K. Ober,Lynden Archer
Publisher : CRC Press
Page : 991 pages
File Size : 51,6 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9780203646991
The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy
Author : William H. Dantzler
Publisher : Springer
Page : 299 pages
File Size : 40,9 Mb
Release : 2016-07-05
Category : Science
ISBN : 9781493937349
This second edition offers a comprehensive overview of the physiological functions of vertebrate kidneys from a comparative viewpoint, with particular emphasis on nonmammalian vertebrates. The topics covered include renal structure; glomerular ultrafiltration; tubular transport of inorganic ions, organic substances, and fluid; and urine dilution and concentration. Mammalian renal function is only considered for purposes of comparison with nonmammalian renal function and as a frame of reference for some of the discussions. The major findings on nonmammalian renal function and the important unanswered questions raised by those findings are described in detail. As such, the book provides comprehensive information on comparative renal function for biological scientists and advanced students of biology with some knowledge of physiology and a desire to know more about renal function in vertebrates, and for mammalian renal physiologists who wish to obtain a broader view of renal function.