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Author : Giannis G. Baltogiannis,Giulio Conte,Pedro Brugada,Juan Sieira,Gaetano M. De Ferrari
Publisher : Frontiers Media SA
Page : 135 pages
File Size : 51,6 Mb
Release : 2021-01-11
Category : Medical
ISBN : 9782889663705
Author : Dierk Thomas,Carol Ann Remme
Publisher : Springer
Page : 436 pages
File Size : 53,8 Mb
Release : 2018-09-10
Category : Medical
ISBN : 9783319778129
This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field. The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications. The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.
Author : A. John Camm
Publisher : Unknown
Page : 3198 pages
File Size : 45,7 Mb
Release : 2019
Category : Cardiology
ISBN : 0198824874
Author : Mohammad Shenasa,N.A. Mark Estes III,Gordon F. Tomaselli
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 45,6 Mb
Release : 2017-11-30
Category : Medical
ISBN : 9780323552691
This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli, will cover Contemporary Challenges in Sudden Cardiac Death. Topics covered in this issue include Pathophysiology; Basic electrophysiological mechanism; Channelopathy and Myopathy as causes of sudden cardiac death; Public access to defibrillation; Sudden cardiac death in children adolescence; Sudden cardiac death in specific cardiomyopathies; Ventricular arrhythmias and sudden cardiac death; lessons learned from cardiac implantable rhythm devices; future directions, and more.
Author : Charles Antzelevitch,Gan-Xin Yan
Publisher : Springer
Page : 0 pages
File Size : 48,7 Mb
Release : 2018-05-30
Category : Medical
ISBN : 3319810685
This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.
Author : Anonim
Publisher : Academic Press
Page : 168 pages
File Size : 46,9 Mb
Release : 2011-09-06
Category : Science
ISBN : 0080923100
Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.
Author : Peter Magnusson,Jo Ann LeQuang
Publisher : BoD – Books on Demand
Page : 198 pages
File Size : 43,9 Mb
Release : 2020-11-19
Category : Medical
ISBN : 9781838800697
Sudden cardiac death is a global health threat for which we have only partial answers. With growing elucidation of the underlying pathophysiological mechanisms of sudden cardiac death, better patient identification and treatment options are being developed. These include risk stratification paradigms, ICD therapy, pharmacological options, ablative procedures, and other treatments. This book covers many of these options, including defibrillator technology and clinical applications. It also examines pathophysiological pathways and etiologies as well as highlights risk-stratification in ion channel diseases and structural heart disease such as dilated cardiomyopathy.
Author : Michael T. Ashworth
Publisher : Cambridge University Press
Page : 361 pages
File Size : 42,5 Mb
Release : 2019-08-22
Category : Medical
ISBN : 9781107116283
Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.
Author : Pietro Delise,Paolo Zeppilli
Publisher : Springer Nature
Page : 196 pages
File Size : 46,9 Mb
Release : 2021-10-21
Category : Medical
ISBN : 9783030804473
Sudden death in athletes is a global problem. Although it is a relatively rare phenomenon (1/100,000 persons), when it does occur, it is often as an incomprehensible event. In fact, it strikes subjects who presumably should be much healthier than the general population. In the previous 20 years, many authors have studied this problem in an attempt to understand the causes and prevent these events, and it has been determined that, in the vast majority of cases, athletes who die suddenly have an underlying heart disease (arrhythmogenic cardiomyopathy, hypertrophic cardiomyopathy, coronary anomalies, channelopathies, etc.). In most cases these diseases do not produce major symptoms and do not preclude sports activity even at the highest levels, although they do increase the incidence of sudden death. How to discover these diseases in asymptomatic athletes is a hotly debated issue. In particular, there is controversy as to whether all athletes should undergo detailed medical screening, including electrocardiogram, or whether the costs of this screening are too high in relation to the event incidence. The purpose of this book is to accurately analyze the causes of sudden death in athletes and to provide cardiologists and sports physicians with useful tips on how to identify at-risk individuals.
Author : Adrian Baranchuk
Publisher : Academic Press
Page : 154 pages
File Size : 40,9 Mb
Release : 2018-03-28
Category : Medical
ISBN : 9780128111529
Brugada Phenocopy: The Art of Recognizing the Brugada ECG Pattern details all aspects associated with alternative diagnosis to Brugada Syndrome (BrS). Coverage includes how to identify the proper ECG pattern, what to do to investigate for BrP, and how to avoid misinterpretations and the use of unnecessary and expensive treatments. Chapters are written by experienced professionals, many of whom are colleagues that initially described this condition. This easy to use volume is a must have reference for researchers of cardiology, cardiologists, electrocardiologists, internists, emergency care doctors and students, residents and fellows. Assists in the proper recognition of the Brugada ECG patterns and how to distinguish true BrS from other conditions with identical ECG Expands understanding on how to properly recognize the ECG of Brugada patterns Contains access to a companion website with video to enhance understanding of proper measurement of the beta angle (Chevallier) and the base of the triangle (Serra)
Author : J. Anthony Gomes
Publisher : Springer Nature
Page : 485 pages
File Size : 54,7 Mb
Release : 2020-06-30
Category : Medical
ISBN : 9783030450663
This engaging book covers a multitude of topics related to heart rhythm disorders (HRDs) and uniquely familiarizes readers with the development of treatment modalities over the past several decades, including the evolution of anti-arrhythmic drugs, pacemakers, defibrillators, and catheter ablation. Organized in ten sections, this title serves as both an archival and a contemporary resource for clinicians. The first section describes the discovery of the circulatory system by William Harvey in 1628 and outlines the development and understanding of HRD since the advent of intra-cardiac electrophysiology. Subsequent sections discuss the historical evolution of abnormal heart rhythms, such as supra and ventricular rhythms and sudden cardiac death, their treatment with drugs, surgery, pacemakers, implantable defibrillators and catheter ablation. Section nine offers a fascinating narration of the clinical evolution of overcoming heart attacks and its impact on HRDs. The final section explores potential new frontiers in HRD and the factors that may contribute to the prospective rise of cardiovascular diseases. A ground-breaking and invaluable addition to the clinical literature, Heart Rhythm Disorders: History, Mechanisms and Management Perspectives details the pervasive nature of cardiovascular diseases in human history, their ramifications, and their projected effects on at-risk demographic populations and human health in general.
Author : John M. Miller
Publisher : Unknown
Page : 0 pages
File Size : 49,9 Mb
Release : 2008
Category : Arrhythmia
ISBN : 1416062750
Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on the Treatment of Cardiac Arrest: Current Status and Future Directions
Publisher : National Academies Press
Page : 456 pages
File Size : 41,8 Mb
Release : 2015-09-29
Category : Medical
ISBN : 9780309372022
Cardiac arrest can strike a seemingly healthy individual of any age, race, ethnicity, or gender at any time in any location, often without warning. Cardiac arrest is the third leading cause of death in the United States, following cancer and heart disease. Four out of five cardiac arrests occur in the home, and more than 90 percent of individuals with cardiac arrest die before reaching the hospital. First and foremost, cardiac arrest treatment is a community issue - local resources and personnel must provide appropriate, high-quality care to save the life of a community member. Time between onset of arrest and provision of care is fundamental, and shortening this time is one of the best ways to reduce the risk of death and disability from cardiac arrest. Specific actions can be implemented now to decrease this time, and recent advances in science could lead to new discoveries in the causes of, and treatments for, cardiac arrest. However, specific barriers must first be addressed. Strategies to Improve Cardiac Arrest Survival examines the complete system of response to cardiac arrest in the United States and identifies opportunities within existing and new treatments, strategies, and research that promise to improve the survival and recovery of patients. The recommendations of Strategies to Improve Cardiac Arrest Survival provide high-priority actions to advance the field as a whole. This report will help citizens, government agencies, and private industry to improve health outcomes from sudden cardiac arrest across the United States.
Author : Peter Kowey,Jonathan P. Piccini,Gerald Naccarelli,James A. Reiffel
Publisher : Springer
Page : 306 pages
File Size : 46,7 Mb
Release : 2017-08-30
Category : Medical
ISBN : 9783319580005
This book provides up-to-date, user-friendly and comprehensive guidance on the evaluation, diagnosis, and medical and surgical treatment of cardiac arrhythmias. This ensures that that this title aids every trainee and practicising cardiologist, cardiac electrophysiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. Cardiovascular Medicine: Cardiac Arrhythmias, Pacing and Sudden Death covers every aspect of cardiac arrhythmias, from cardiac signs and symptoms through imaging and the genetic basis for disease to surgery, interventions, treatment and preventive cardiology. This coverage is presented with consistent chapter organization, clear design, and engaging text that includes user-friendly features such as tables, lists and treatment boxes.
Author : Ihor Gussak,A. A. M. Wilde,P. A. Friedman,Charles Antzelevitch,M. J. Ackerman,W.-K. Shen
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 49,8 Mb
Release : 2008-09-08
Category : Medical
ISBN : 9781846288548
This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.