Sugar Chains

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Sugar Chains

Author : Tadashi Suzuki,Kazuaki Ohtsubo,Naoyuki Taniguchi
Publisher : Springer
Page : 288 pages
File Size : 54,6 Mb
Release : 2015-02-02
Category : Science
ISBN : 9784431553816

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Sugar Chains by Tadashi Suzuki,Kazuaki Ohtsubo,Naoyuki Taniguchi Pdf

This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a “face” of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding “glyco-related” questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent “textbook” for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.

Experimental Glycoscience

Author : Naoyuki Taniguchi,Akemi Suzuki,Yukishige Ito,Hisashi Narimatsu,Toshisuke Kawasaki,Sumihiro Hase
Publisher : Springer Science & Business Media
Page : 255 pages
File Size : 40,9 Mb
Release : 2009-03-08
Category : Science
ISBN : 9784431779247

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Experimental Glycoscience by Naoyuki Taniguchi,Akemi Suzuki,Yukishige Ito,Hisashi Narimatsu,Toshisuke Kawasaki,Sumihiro Hase Pdf

The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Glycoanalysis Protocols

Author : Elizabeth F. Hounsell
Publisher : Springer Science & Business Media
Page : 263 pages
File Size : 41,7 Mb
Release : 2008-02-02
Category : Science
ISBN : 9781592595624

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Glycoanalysis Protocols by Elizabeth F. Hounsell Pdf

Now fully updated and considerably expanded, Glycoanalysis Protocols, 2nd ed., makes available to all protein scientists, and particularly those working with today's pharmaceuticals, the most advanced and reproducible glycoanalysis techniques currently in use. Developed by highly experienced carbohydrate chemists, biochemists, and physical chemists, these detailed, up-to-date, and proven analytical techniques cover the areas of glycoprotein macromolecular structural analysis, oligosaccharide profiling, lipid conjugate characterization, microorganism structure determination, and proteoglycan function. Special attention has been given to advanced analytical techniques in biotechnology during the production of recombinant glycoproteins and other therapeutics. Hailed as "indispensable" in its first edition, Glycoanalysis Protocols, 2nd ed., continues with vital, time-tested techniques addressing the needs of both biomedical researchers and protein macromolecular structural chemists. It will well serve all those starting work on the analysis of glycoproteins, as well as more experienced investigators seeking to augment their expertise.

Essentials of Glycobiology

Author : Ajit Varki,Maarten J. Chrispeels
Publisher : CSHL Press
Page : 694 pages
File Size : 43,8 Mb
Release : 1999
Category : Medical
ISBN : 0879696818

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Essentials of Glycobiology by Ajit Varki,Maarten J. Chrispeels Pdf

Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Global Value Chains in Latin America

Author : Pablo Pérez Akaki,Marisol Velázquez-Salazar,Gilma Sabina Lizama Gaitán
Publisher : Springer Nature
Page : 336 pages
File Size : 47,8 Mb
Release : 2023-07-15
Category : Business & Economics
ISBN : 9783031331039

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Global Value Chains in Latin America by Pablo Pérez Akaki,Marisol Velázquez-Salazar,Gilma Sabina Lizama Gaitán Pdf

​This book examines the governance and institutional dimensions of the global value chain (GVC) and the barriers of local firms to participate in chains. Focusing on Latin America, this collection analyzes agribusiness and agri-food chains in order to evaluate the common challenges in the production and trade of coffee, cocoa, maize, sugar, Tequila and Mezcal in Mexico and Central America. Additionally, there are studies of knowledge-intensive industries of aerospace and automotive. Addressing the need for sustainable economic development in developing countries from the study of value chains, this work presents a conceptual framework and empirical cases that highlight the impact of GVC in the Latin American region and will appeal to international business and international trade researchers.

Plant-microbe Interactions 2

Author : Gary Stacey,Noel T. Keen
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 42,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461560531

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Plant-microbe Interactions 2 by Gary Stacey,Noel T. Keen Pdf

Plant-Microbe Interactions, Volume 2 Volume 1 of this series has made its appearance and dealt forcefully with impor tant current topics in the field of plant-microbe interactions. We believe that the quality of those chapters was high and should serve as a focal point for the state of the art as well as an enduring reference. Volume 2 builds upon these accom plishments. Chapter 1 discusses the fascinating lipo-chitin signal molecules from Rhizo bium, aspects regarding their biosynthesis, and the basis for host specificity. These molecules are a cardinal example of how microorganisms influence plant development and stimulate speculation that they have identified a previously un known aspect of plant hormone activity. Chapter 2 continues the discussion of Rhizobium by considering the trafficking of carbon and nitrogen in nodules. Al though the ostensible advantage of nodules to plants is the fixation of atmos pheric nitrogen, the actual process involved in supplying reduced nitrogen to the plant host is complex.

EJB Reviews

Author : Anonim
Publisher : Unknown
Page : 558 pages
File Size : 42,8 Mb
Release : 1992
Category : Biochemistry
ISBN : UOM:39015027129512

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EJB Reviews by Anonim Pdf

From Clone to Clinic

Author : Daan J.A. Crommelin,H. Schellekens
Publisher : Springer Science & Business Media
Page : 372 pages
File Size : 42,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401137805

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From Clone to Clinic by Daan J.A. Crommelin,H. Schellekens Pdf

This book contains a selection of the papers presented at the meeting "Between Clone and Clinic" which was organised in March 1990 in Amsterdam by the dutch Organisation for Applied Research, TNO, and the University of Utrecht. The scope of this meeting was the development of biotechnological pharmaceuticals mainly made by recombinant DNA technology or monoclonal antibody techniques. All aspects concerning the development of the products after host cells producing them are obtained where discussed. The meeting was attended by twohundred specialists from all over the globe, including phar macologists, toxicologists, registration experts, Quality Assurence managers, production en gineers and physicians. Biotechnological pharmaceuticals are in general large and complex protein molecules. Bringing these products to the market poses other problems than encountered with the classical chemical drugs. The source of biotechnological pharmaceuticals are living cells. The function of cells are depend ent on many factors and the stability of production may be a problem. Good Laboratory and Manufactory Practices with Quality Control (GLP and GMP) are of paramount importance and are discussed in a number of papers. The products of the new biotechnology are often highly specific and only active in the human species. Also the side effects can only be studied in the clinical setting. Even when the product is active in animals there is the problem of antigenicity. During treatment the animals will produce antibodies which neutralise the activity. So safety testing may prove difficult.

Encyclopedia of Endocrine Diseases

Author : Luciano Martini
Publisher : Academic Press
Page : 816 pages
File Size : 55,7 Mb
Release : 2004
Category : Medical
ISBN : 0124755720

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Encyclopedia of Endocrine Diseases by Luciano Martini Pdf

The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This encyclopedia is an essential addition to any library collection written to be accessible for both the clinical and non-clinical reader. Associate Editors include: Eli Y. Adashi, John P. Bilezikian, George P. Chrousos, Junichi Fukata, Julianne Imperato-McGinley, Hiroo Imura, Antonio Liuzzi, Frank L. Moore, Daniel Porte, Jens F. Rehfeld, Ellis Samols, Gustav Schonfeld, Pierre C. Sizonenko, Wilmar M. Wiersinga. Also available online via ScienceDirect featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. * Includes nearly 500 entries addressing all aspects of endocrine diseases * More than 800 eminent researchers contributed from 25 different countries around the world * More than 900 figures and 450 tables displayed * Comprehensive glossary comprising 1500 definitions * The Editor-in-Chief is former editor of the journal Frontiers in Neuroendocrinology and has contributed to over 40 books in the field of endocrinology.

Stability and Stabilization of Enzymes

Author : W.J.J. van den Tweel,A. Harder,R.M. Buitelaar
Publisher : Elsevier
Page : 535 pages
File Size : 42,8 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483291338

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Stability and Stabilization of Enzymes by W.J.J. van den Tweel,A. Harder,R.M. Buitelaar Pdf

These proceedings contain most of the oral presentations and posters of the international symposium on Stability and Stabilization of Enzymes held in Maastricht in November 1992. They provide a comprehensive overview of the state-of-the-art in this field. The possible applications of enzymes are enormous. Years of development have seen many enzymes brought onto the market, but they are still expensive to use. Therefore, their efficient application is a prerequisite for common usage. One of the main factors for this efficiency is the stability of the enzymes. The topics thus ranged from the extensive fundamental thermodynamic knowledge gathered in academic research to the practical applied knowledge built up in industry during the time that enzymes have been produced commercially. The subject Stability and Stabilization of Enzymes was discussed from various points of view, as was reflected in the themes of the symposium sessions. In the session on Fundamentals of Enzyme Stabilisation the thermodynamic background of the phenomenon was highlighted. In yet another session, the recently developed analytical tools to measure enzyme stability and stabilisation were discussed. Further sessions comprised the physical, chemical and biological ways to obtain enzyme stabilisation and finally, the industrial practice of enzyme stabilisation was treated by representatives of the world's most important enzyme producers. The book will be of interest to researchers in universities and industry in the fields of biochemistry, enzymology and biotechnology.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Journal of Cellular Biochemistry

Author : Anonim
Publisher : Unknown
Page : 452 pages
File Size : 52,8 Mb
Release : 1988
Category : Biochemistry
ISBN : UCAL:B5032943

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Journal of Cellular Biochemistry by Anonim Pdf

Nutrition

Author : Lori A. Smolin,Mary B. Grosvenor,Debbie Gurfinkel
Publisher : John Wiley & Sons
Page : 978 pages
File Size : 46,9 Mb
Release : 2020-06-23
Category : Science
ISBN : 9781119577546

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Nutrition by Lori A. Smolin,Mary B. Grosvenor,Debbie Gurfinkel Pdf

Nutrition: Science and Applications, 3rd Canadian Edition, provides students with a strong foundational knowledge of human nutrition, covering all essential nutrients, their functions in the body, and their sources and dietary components. Presenting an innovative critical-thinking approach to the subject, this leading textbook goes beyond the basics to explore underlying nutrition processes while discussing the latest research, debates, and controversies related to nutrition and health. The text offers an accessible, visually-rich presentation of topics designed to be highly relevant and relatable to Canadian readers. The ideal text for college-level nutrition courses, this new edition features extensively revised and updated content throughout — aligning with the latest nutrition research, recommendations, guidelines, and Canadian government regulations. The authors real-world approach enables students to apply concepts of nutrition science in their own lives as consumers, and in their future careers as scientists and health professionals. Balanced coverage of fundamental nutrition topics integrates with comprehensive discussion of nutrient metabolism, health and disease relationships, dietary patterns, Canadian and global nutrition issues, and much more.

Membrane Dynamics and Domains

Author : Peter J. Quinn
Publisher : Springer Science & Business Media
Page : 502 pages
File Size : 40,6 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475758061

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Membrane Dynamics and Domains by Peter J. Quinn Pdf

The fluid-mosaic model of membrane structure formulated by Singer and Nicolson in the early 1970s has proven to be a durable concept in terms of the principles governing the organization of the constituent lipids and proteins. During the past 30 or so years a great deal of information has accumulated on the composition of various cell membranes and how this is related to the dif ferent functions that membranes perform. Nevertheless, the task of explaining particular functions at the molecular level has been hampered by lack of struc tural detail at the atomic level. The reason for this is primarily the difficulty of crystallizing membrane proteins which require strategies that differ from those used to crystallize soluble proteins. The unique exception is bacteriorhodopsin of the purple membrane of Halobacterium halobium which is interpolated into a membrane that is neither fluid nor in a mosaic configuration. To date only 50 or so membrane proteins have been characterised to atomic resolution by diffraction methods, in contrast to the vast data accumulated on soluble proteins. Another factor that has been difficult to explain is the reason why the lipid compliment of membranes is often extremely complex. Many hundreds of different molecular species of lipid can be identified in some membranes. Remarkably, the particular composition of each membrane appears to be main tained within relatively narrow limits and its identity distinguished from other morphologically-distinct membranes.