Target Product Profile For A Diagnostic Test To Detect Mycobacterium Leprae Infection Among Asymptomatic Household And Familial Contacts Of Leprosy Patients

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Target product profile for a diagnostic test to detect Mycobacterium leprae infection among asymptomatic household and familial contacts of leprosy patients

Author : World Health Organization
Publisher : World Health Organization
Page : 18 pages
File Size : 41,6 Mb
Release : 2023-07-24
Category : Medical
ISBN : 9789240074231

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Target product profile for a diagnostic test to detect Mycobacterium leprae infection among asymptomatic household and familial contacts of leprosy patients by World Health Organization Pdf

Global report on neglected tropical diseases 2024

Author : World Health Organization
Publisher : World Health Organization
Page : 86 pages
File Size : 40,8 Mb
Release : 2024-05-04
Category : Medical
ISBN : 9789240091535

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Global report on neglected tropical diseases 2024 by World Health Organization Pdf

This document is the second in a series of global reports describing progress towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021–2030. It describes a wide range of activities, accomplishments and challenges across the portfolio of NTDs and across all six WHO regions. The report presents epidemiological and programmatic data for 2022, which were gathered, compiled and analysed in 2023. In some cases, 2023 data are available and presented; in other cases, less recent information is included, when 2022 data are not available. In addition, it presents the main facts or events that occurred in 2023. In line with the road map’s companion document Ending the neglect to attain the Sustainable Development Goals: a framework for monitoring and evaluating progress of the road map for neglected tropical diseases 2021−2030, the report includes quantitative information on the status of the overarching, cross-cutting and disease-specific indicators. This is followed by qualitative information on each of the three road map pillars and on regional and country progress. The conclusions of the report and way forward are further complemented by annexes on cross-cutting indicator 6, status of donated medicines for treatment of NTDs, articles on NTDs published in the Weekly Epidemiological Record, target product profiles published as of 31 December 2023 and the list of global NTD reports published by WHO so far.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 43,7 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Case Studies in Infectious Disease: Mycobacterium Leprae

Author : Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward
Publisher : Garland Science
Page : 23 pages
File Size : 46,5 Mb
Release : 2009-12
Category : Medical
ISBN : 9781136986482

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Case Studies in Infectious Disease: Mycobacterium Leprae by Peter Lydyard,Michael Cole,John Holton,Will Irving,Nino Porakishvili,Pradhib Venkatesan,Kate Ward Pdf

Case Studies in Infectious Disease: Mycobacterium leprae presents the natural history of this infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis, and treatment. A set of core questions explores the nature, causation, host response, manifestations, and management of this infectious process. This case also includes summary bullet points, questions and answers, and references.

Mycobacterial Skin Infections

Author : Domenico Bonamonte,Gianni Angelini
Publisher : Springer
Page : 398 pages
File Size : 52,6 Mb
Release : 2017-09-04
Category : Medical
ISBN : 9783319485386

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Mycobacterial Skin Infections by Domenico Bonamonte,Gianni Angelini Pdf

This well-illustrated book is a comprehensive guide to the cutaneous clinical presentations of mycobacterial infections. The Mycobacterium genus includes over 170 species, nontuberculous mycobacteria (NTM) having been added to the obligate human pathogens such as M. tuberculosis and M. leprae. NTM are widely distributed in the environment with high isolation rates worldwide; the skin is a major target with variable clinical manifestations. A current resurgence in tuberculosis is aggravated by the synergy with human immunodeficiency virus, the breakdown of health care systems, and the rise in multidrug-resistant disease, as the incidence of leprosy remains stable, at around 250,000 new cases annually, regardless of effective antibiotic therapy. Presentations of various cutaneous infections caused by mycobacteria may be overlooked by clinicians owing the lack of familiarity with tuberculosis, leprosy, and the related NTM clinical features. This handy guide will help the dermatologist to spot the different clinical manifestations, make a prompt diagnosis, and apply effective treatment.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Author : World Health Organization
Publisher : World Health Organization
Page : 211 pages
File Size : 50,5 Mb
Release : 2015-08-05
Category : Medical
ISBN : 9789241564861

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Investing to Overcome the Global Impact of Neglected Tropical Diseases by World Health Organization Pdf

"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Buruli Ulcer

Author : Gerd Pluschke,Katharina Röltgen
Publisher : Springer
Page : 287 pages
File Size : 44,8 Mb
Release : 2019-04-29
Category : Medical
ISBN : 9783030111144

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Buruli Ulcer by Gerd Pluschke,Katharina Röltgen Pdf

A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Diagnosis and Control of Johne's Disease

Author : National Research Council,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Diagnosis and Control of Johne's Disease
Publisher : National Academies Press
Page : 243 pages
File Size : 52,5 Mb
Release : 2003-08-13
Category : Medical
ISBN : 9780309168441

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Diagnosis and Control of Johne's Disease by National Research Council,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Diagnosis and Control of Johne's Disease Pdf

Johne's Disease is a chronic, progressive intestinal disease caused by infection with Mycobacterium avium subspecies paratuberculosis (Map) that affects primarily ruminant animals. In recent decades there has been growing concern over the lack of effective control of this disease and questions have arisen regarding the possibility that Map infection could be a cause of some cases of Crohn's disease in humans. This report presents a broad outline of the steps that should be taken to control Johne's disease, reduce the spread of Map, and minimize effects of the disease in animals. The report also describes the weaknesses of our current research agenda and provides recommendations for a new research strategy to resolve the question of whether there is a link between Johne's and Crohn's diseases.

Tuberculosis

Author : Barry R. Bloom
Publisher : Unknown
Page : 664 pages
File Size : 45,6 Mb
Release : 1994
Category : Medical
ISBN : UOM:39015035754277

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Tuberculosis by Barry R. Bloom Pdf

The authors discuss fundamental questions about the biology, genetics, mechanisms of pathogenicity, mechanisms of resistance, and drug development strategies that are likely to provide important new knowledge about TB and new interventions to prevent and treat this disease.

Saliva Protection and Transmissible Diseases

Author : Crispian Scully,Jacobo Limeres Posse,Pedro Diz Dios
Publisher : Academic Press
Page : 122 pages
File Size : 41,6 Mb
Release : 2017-07-19
Category : Medical
ISBN : 9780128136829

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Saliva Protection and Transmissible Diseases by Crispian Scully,Jacobo Limeres Posse,Pedro Diz Dios Pdf

Saliva Protection and Transmissible Diseases provides a review of saliva protection, raising debate on micro-organisms potentially transmissible in saliva, and also considering the evidence on diseases that may be transmitted by kissing. Saliva is a complex body fluid essential to health, especially mastication, swallowing and speech, and hyposalivation can lead to dysfunction and even infection. More serious pathogens, such as herpes viruses and papillomaviruses can be conveyed by kissing, as can potentially lethal micro-organisms present in some saliva, such as meningococci, fungal organisms and Ebola viruses. Stipulates the defensive roles of saliva, an important topic not previously reviewed in-depth in literature Provides awareness that saliva also transmits infectious agents that can produce serious or even lethal diseases Gives understanding that kissing may be an at-risk practice

Neurologic Differential Diagnosis

Author : Alan B. Ettinger,Deborah M. Weisbrot
Publisher : Cambridge University Press
Page : 693 pages
File Size : 40,5 Mb
Release : 2014-04-17
Category : Medical
ISBN : 9781107014558

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Neurologic Differential Diagnosis by Alan B. Ettinger,Deborah M. Weisbrot Pdf

Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.

Equity, Social Determinants and Public Health Programmes

Author : World Health Organization
Publisher : World Health Organization
Page : 302 pages
File Size : 51,5 Mb
Release : 2010
Category : Health & Fitness
ISBN : 9789241563970

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Equity, Social Determinants and Public Health Programmes by World Health Organization Pdf

1. Introduction and methods of work.-- 2. Alcohol: equity and social determinants.-- 3. Cardiovascular disease: equity and social determinants.-- 4. Health and nutrition of children: equity and social determinants.-- 5. Diabetes: equity and social determinants.-- 6. Food safety: equity and social determinants.-- 7. Mental disorders: equity and social determinants.-- 8. Neglected tropical diseases: equity and social determinants.-- 9. Oral health: equity and social determinants.-- 10. Unintended pregnancy and pregnancy outcome: equity and social determinants.-- 11. Tobacco use: equity and social determinants.-- 12. Tuberculosis: the role of risk factors and social determinants.-- 13. Violence and unintentional injury: equity and social determinants.-- 14. Synergy for equity.

Contemporary Oral Medicine

Author : Camile S. Farah,Ramesh Balasubramaniam,Michael J. McCullough
Publisher : Springer
Page : 0 pages
File Size : 45,6 Mb
Release : 2019-03-07
Category : Medical
ISBN : 3319723014

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Contemporary Oral Medicine by Camile S. Farah,Ramesh Balasubramaniam,Michael J. McCullough Pdf

This book, written by world authorities in the field, is a comprehensive, up-to-date guide to the specialty of Oral Medicine, which is concerned with the diagnosis, prevention, and predominantly non-surgical management of medically related disorders and conditions affecting the oral and maxillofacial region. The pathophysiology, clinical presentation, diagnostic evaluation, and treatment of all relevant diseases and disorders are described with the aid of a wealth of clinical cases and illustrations that enable the reader to appreciate the diversity and potential complexity of Oral Medicine. In addition to the wide-ranging coverage of oral conditions, separate sections are devoted to bone and cutaneous pathology and to orofacial pain and its management, in addition to dental sleep medicine. The clinician who treats Oral Medicine patients will find this book to be an excellent aid to optimal management grounded in a sound knowledge of basic science and the dental and medical aspects of each disorder. In addition, it will serve as an outstanding textbook for undergraduate and postgraduate students.

Tuberculosis

Author : Lee B. Reichman,Earl S. Hershfield
Publisher : Unknown
Page : 792 pages
File Size : 53,9 Mb
Release : 1993
Category : Tuberculosis
ISBN : UOM:39015029720920

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Tuberculosis by Lee B. Reichman,Earl S. Hershfield Pdf