Taurine 10

Author : Dong-Hee Lee,Stephen W. Schaffer,Eunkyue Park,Ha Won Kim
Publisher : Springer
Page : 1181 pages
File Size : 53,6 Mb
Release : 2017-08-28
Category : Science
ISBN : 9789402410792

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Taurine 10 by Dong-Hee Lee,Stephen W. Schaffer,Eunkyue Park,Ha Won Kim Pdf

Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.

Author : John B. Lombardini,Stephen W. Schaffer,Junichi Azuma
Publisher : Springer Science & Business Media
Page : 456 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461534365

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Taurine by John B. Lombardini,Stephen W. Schaffer,Junichi Azuma Pdf

The underlying philosophy of these two symposia on taurine remains the same as all those that have been held previously: the best way to remain current in the subject matter is to talk directly with the investigators at the forefront of the field. Thus, we brought together some 50 individuals from 11 different countries who have keen interests and active research programs in the many-faceted areas of taurine research. The meetings were held on October 8-10, 1991, in an elegant setting in a resort area at Orange Beach, Alabama, approximately 50 miles outside of Mobile on the Gulf Coast. The meetings were programmed as two separate Symposia held sequentially. The first symposia on October 8 was devoted exclusively to taurine research in the cat, primarily in the area of nutrition, and entitled "The Waltham Symposium on Taurine and Cat Nutrition". The second symposia on October 9 and 10 was open to all fields of taurine research and was entitled "International Taurine Symposium: New Dimensions on its Mechanisms of Actions". If the philosophy of these meetings was to bring both experts and novices together in a discussion and presentation of current taurine research, then the major purpose of the Proceedings is to document the current research efforts and to present an objective summary of where the taurine field stands today and where the focus will be in the future.

Author : Ryan J. Huxtable,Dietrich Michalk
Publisher : Springer Science & Business Media
Page : 447 pages
File Size : 40,8 Mb
Release : 2013-11-21
Category : Science
ISBN : 9781489914712

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Taurine in Health and Disease by Ryan J. Huxtable,Dietrich Michalk Pdf

Taurine, or 2-aminoethane sulfonic acid, has long been known to be the major organic product formed from the breakdown of the sulfur-containing amino acids, methionine and cysteine. It is excreted as such in the urine or as bile acid conjugates in the bile. Research over the last 25 years, however, has uncovered an amazing variety of phenomena involving taurine. Despite the fact that the mechanism of action of taurine in some of these phenomena remains to be elucidated, it is clear that taurine is of far more physiological relevance than being the mere metabolic debris of sulfur amino acid catabolism. It also has numerous pharmacological actions that are beginning to be developed, as exemplified by some of the studies reported in this volume. This volume reports the proceedings of the latest of a series of international symposia, continuing on from the initial meeting held in Tucson, Arizona, in 1975. The latest symposium was the first to be held in Germany, in Cologne from August 29 through September 1, 1993. It continued the multidisciplinary approach that has been the norm for taurine symposia. We hope the publication of the proceedings will stimulate further investigations on this simple but fascinating compound.

Author : Denis Noble,Yung E Earm
Publisher : Springer Science & Business Media
Page : 180 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461530749

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Ionic Channels and Effect of Taurine on the Heart by Denis Noble,Yung E Earm Pdf

This book is based on papers presented at a Symposium held in Seoul, Korea in 1992. The idea for the symposium developed naturally from work in which Professor Yung E Earm, at Seoul National University, had been involved both in my laboratory in Oxford and in his own laboratory in Seoul concerning the possible role of certain amino acids, like taurine that are strongly concentrated by the cells of the heart, and the relationship between such acids and membrane ionic currents. The first obvious question was whether it is possible to identify the transport mechanisms involved for taurine and whether they are electrogenic. The second question is what function could be served by such processes: does taurine play an essential role in cardiac tissue and is this important in protecting the heart from disease? With his colleagues in the Korean Physiological Society, Professor Earm set about the task of fmancing and organizing a meeting at which some of the world's leading cardiac electrophysiologists and taurine specialists could discuss these questions. The fmance was generously provided by the Dong-A Pharmaceutical Company, one of the leading scientific companies in Korea.

Author : Ryan J. Huxtable,Junichi Azuma,Kinya Kuriyama,Masao Nakagawa,Akemichi Baba
Publisher : Springer Science & Business Media
Page : 631 pages
File Size : 50,9 Mb
Release : 2013-11-21
Category : Science
ISBN : 9781489901828

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Taurine 2 by Ryan J. Huxtable,Junichi Azuma,Kinya Kuriyama,Masao Nakagawa,Akemichi Baba Pdf

This volume comprises the edited proceedings of the International Taurine Sympo sium held in Osaka, Japan, in June 1995, as a Satellite Symposium of the 15th Biennial of the International Society for Neurochemistry. This Taurine Symposium was the Meeting latest in a series held since 1975 at approximately two-year intervals by an informal group of international researchers. It attracted contributions from 20 countries, ranging from Armenia via Finland and Spain to the United States. Some 121 participants attended. The Symposium was organized and chaired by Junichi Azuma, University of Osaka. Other members of the Organizing Committee in Japan consisted of Kinya Kuriyama and Masao Nakagawa, both from the Kyoto Prefectural University of Medicine, and Akemichi Baba, from Osaka University. The Committee had to contend with the disaster of the Kobe earthquake, which struck on January 21. The epicenter was only around 25 miles from the meeting site, and the quake demolished the home of one Committee member. Despite this unnaturally natural handicap, the participants experienced a superbly organized meeting, one which more than maintained the high social and scientific standards established for this series. In his Welcome Message, Dr. Azuma listed a threefold objective for the Symposium: To provide a forum for the interdisciplinary exchange of information on taurine; to give an opportunity for renewing old friendships and making new friends; and to promote coopera tion among participants from around the world.

Author : Heitaroh Iwata,John B. Lombardini,Tomio Segawa
Publisher : Springer Science & Business Media
Page : 180 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461316473

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Taurine and the Heart by Heitaroh Iwata,John B. Lombardini,Tomio Segawa Pdf

The first Taurine Symposium organized by Dr. Ryan Huxtable and the late Dr. Andre Barbeau was held in Tucson, Arizona, in 1975. Since that auspici ous event, nine international symposia on the role of taurine in biology have taken place. The locations for these meetings have been Tucson (two times), Rome, Philadelphia, Tokyo, Vancouver, Mexico City, Helsinki, and Florence. In 1977, due to the large number of scientists in Japan who were interested in the role of this unique amino acid in biological systems, we organized the Japanese Research Society on Sulfur Amino Acids with the encouragement and financial assistance of the Taisho Pharmaceutical Co., Ltd (Tokyo). Annual meetings have been held, and the membership has expanded from 78 to 414 in 1987; the number of presentations has increased during this time span from 29 to 74. The symposium in Tokyo in 1982, "Sulfur Amino Acids, Biochemical and Clinical Aspects" [1], was held to celebrate the 5th Annual Meeting of our Society. I would like to emphasize that in Japan we have an active Research Society especially directed to the study of sulfur amino acids. We have published our own semi-annual journal entitled Sulfur Amino Acids. Our society is an inter disciplinary research society since taurine is a highly diversified compound that interconnects physiology, biochemistry, pharmacology, nutrition, and medicine. One exciting fringe benefit of taurine research and the society has been the fostering of contacts with distinguished scientists from many varied medical fields.

Author : James J. Kocsis,S.I. Baskin,Stephen W. Schaffer
Publisher : Springer Science & Business Media
Page : 435 pages
File Size : 45,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400980938

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The Effects of Taurine on Excitable Tissues by James J. Kocsis,S.I. Baskin,Stephen W. Schaffer Pdf

It has become an annual custom for the Physiological Society of Philadel phia to sponsor a spring symposium in honor of A. N. Richards (\876-1966), a research pharmacologist who developed the classical micropuncture tech nique for studying kidney function. The A. N. Richards Symposium for 1979 was held on April 23-24 in Valley Forge, Pennsylvania. The theme of this symposium was "The Actions of Taurine on Excitable Tissues." Although taurine was discovered as a constituent of bile salts in 1857 by a chemist and an anatomist (Gmelin and Tiedemann), interest today centers chiefly on the extrahepatic actions of taurine, especially in brain, heart, and other excitable tissues. Research on taurine is clearly in a period of exponential growth. We can be sure that the research reports presented and described herein as the "Proceedings of the Symposium" will provide impetus for further growth. Thus the report describing macromolecular receptors for taurine in myocardial sarcolemma may provide a model for exploring the molecular mechanisms that underlie the action(s) of taurine. Stabilization of mem branes and modulation of ion fluxes are two fundamental actions of taurine dealt with in many of these reports. It is just these actions of taurine that have been reported by several investigators as being involved in human myotonia, diabetes, and heart failure.

Author : Abdeslem El Idrissi,William J. L'Amoreaux
Publisher : Springer Science & Business Media
Page : 442 pages
File Size : 46,5 Mb
Release : 2013-02-11
Category : Science
ISBN : 9781461461302

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Taurine 8 by Abdeslem El Idrissi,William J. L'Amoreaux Pdf

Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in the Nervous System, Taurine in the Immune System, Taurine and Diabetes, and Taurine and the Cardiovascular System. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L’Amoreaux, College of Staten Island, were co-chairs of the Organizing Committee for the meeting. Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.

Author : Stephen W. Schaffer,John B. Lombardini,Ryan J. Huxtable
Publisher : Springer Science & Business Media
Page : 510 pages
File Size : 44,5 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781489901170

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Taurine 3 by Stephen W. Schaffer,John B. Lombardini,Ryan J. Huxtable Pdf

Proceedings of the International Taurine Symposium '97: Neurochemistry, Biochemistry, and Pharmacology held in Tucson, Arizona, July 15-19, 1997

Author : Junichi Azuma,Stephen W. Schaffer,Takashi Ito
Publisher : Springer Science & Business Media
Page : 526 pages
File Size : 41,8 Mb
Release : 2008-11-05
Category : Medical
ISBN : 9780387756813

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Taurine 7 by Junichi Azuma,Stephen W. Schaffer,Takashi Ito Pdf

Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. It is present at relatively high concentrations in all electrically excitable tissues such as brain, sensory organs, heart, and muscle, and in certain endocrine glands. Some of its physiological functions are already established, for example as an essential nutrient during development and as a neuromodulator or osmolyte, but the cellular mechanisms are still mostly a matter of conjecture. Moreover, there are a number of other putative functions of taurine less well known at present. Taurine 7 contains the proceedings of the 16th International Taurine Meeting. This meeting is a multidisciplinary symposium, with participants presenting different fields of biological science. This volume focuses on all aspects of taurine research from immunology and its effect on health to chemistry and biochemistry, including future clinical applications.

Author : Laura Della Corte,Ryan J. Huxtable,Giampietro Sgaragli,Keith F. Tipton
Publisher : Springer Science & Business Media
Page : 647 pages
File Size : 41,7 Mb
Release : 2005-12-07
Category : Science
ISBN : 9780306468384

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Taurine 4 by Laura Della Corte,Ryan J. Huxtable,Giampietro Sgaragli,Keith F. Tipton Pdf

Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3μM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .

Author : John B. Lombardini,Stephen W. Schaffer,Junichi Azuma
Publisher : Springer Science & Business Media
Page : 574 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461500773

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Taurine 5 by John B. Lombardini,Stephen W. Schaffer,Junichi Azuma Pdf

The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.

Author : Ryan J. Huxtable,F. Franconi,A. Giotti
Publisher : Springer Science & Business Media
Page : 397 pages
File Size : 51,8 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9781489904058

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The Biology of Taurine by Ryan J. Huxtable,F. Franconi,A. Giotti Pdf

I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The book is the outcome of the Symposium held in Firenze-San Miniato (PI), October 6-9, 1986. The symposium was entitled "Sulfur Amino Acids, Peptides and Related Compounds" and was the 7th international symposium on taurine ßnd assooiated substances. It is always difficult to introduce, with the right brevity end emphasis, a topic which has been studied in depth by numerous experte. Nevertheless, I shall do my best to give a historical perspeotive of the subjects of the meeting which I consider to be very important for the frontiers of researoh on taurine. ~he following topios have also beoome coherent areas of study during the development of researoh on taurine: metabolism, nutrition, neurochemistry, cardiovasoular regulation. Although taurine was isolated in 1821 by ~iedman and Gmel1n, its only biochemioal role known at the time was the synthesis of bile saIte in mammalian tissue. There has been an inoreasing interest in the biologioal action of taurine from metabolio aspects to other biologioal aspects (nutrition, development, eto.). In 1975 it was first demonstrated that taurine deprivation produoed retinal degeneration in cats; more reoent studies showed that a taurine-free diet or the administration of taurine transport inhibitors caused retinal degeneration in other mammlas. More reoent studies have pointed out the role of taurine in development, and the first part of this book is dedicated to these topios

Author : Ryan J. Huxtable
Publisher : Springer Science & Business Media
Page : 547 pages
File Size : 43,8 Mb
Release : 2013-04-09
Category : Medical
ISBN : 9781475704020

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Taurine in Nutrition and Neurology by Ryan J. Huxtable Pdf

Author : Jianmin Hu,Fengyuan Piao,Stephen W. Schaffer,Abdeslem El Idrissi,Jang-Yen Wu
Publisher : Springer Nature
Page : 1081 pages
File Size : 55,8 Mb
Release : 2019-08-29
Category : Science
ISBN : 9789811380235

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Taurine 11 by Jianmin Hu,Fengyuan Piao,Stephen W. Schaffer,Abdeslem El Idrissi,Jang-Yen Wu Pdf

This book gathers a selection of original articles and critical reviews presented at the 21st International Taurine Meeting, held in Shenyang, China in May 2018, which discussed and disseminated the latest findings on taurine, especially in human life. The book is divided into eight parts, which respectively address: Taurine and Metabolism, Taurine and Nutrition, Taurine and Organ Dysfunction, Taurine and Heart Health, Taurine and Anti-cancer, Taurine and Anti-oxidation / Anti-microbial, Taurine and Neuroprotection, and Taurine and Anti-inflammatory. These latest discoveries concerning the functions and advantageous effects of taurine on the health of various human body systems will not only advance the treatment of human diseases and the quality of human life, but also promote further research into the applications of taurine in human health.