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Author : Committee on Problems of Drug Dependence (U.S.)
Publisher : Unknown
Page : 172 pages
File Size : 48,9 Mb
Release : 1984
Category : Drug abuse
ISBN : MINN:319510001647361
Author : Marian W. Fischman,Nancy K. Mello
Publisher : Unknown
Page : 420 pages
File Size : 54,8 Mb
Release : 1989
Category : Drug abuse
ISBN : MINN:31951D00426555C
Representatives from industry, academia and government discuss issues related to testing for drug abuse liability and dependence potential. Contributors critically assess current methods for evaluating drugs in human subjects and describe both the advantages and limitations of each approach. This information permits identification of areas in which further research and development are needed.
Author : Carrie Markgraf,Thomas Hudzik,David Compton
Publisher : Academic Press
Page : 320 pages
File Size : 54,7 Mb
Release : 2015-07-14
Category : Medical
ISBN : 9780124202160
Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
Author : Anonim
Publisher : Unknown
Page : 432 pages
File Size : 54,9 Mb
Release : 1976
Category : Drug abuse
ISBN : COLUMBIA:HR01751905
Author : College on Problems of Drug Dependence (U.S.). Scientific Meeting
Publisher : Unknown
Page : 308 pages
File Size : 47,5 Mb
Release : 1994
Category : Drug abuse
ISBN : IND:30000130069150
Author : Barry Stimmel
Publisher : Routledge
Page : 197 pages
File Size : 45,7 Mb
Release : 2013-12-02
Category : Medical
ISBN : 9781317839477
Increase your awareness of the relative addiction liabilities of various drugs and drug classes that are commonly abused. A timely and masterful new book, Addiction Potential of Abused Drugs and Drug Classes clarifies, in contemporary terminology, the state of addiction liability of cocaine, opiates, alcohol, sedative-hypnotics, nicotine, anxiolytics, marijuana, inhalants and anesthetics, and PCP and hallucinogens--the nine drugs that are most abused today. Authorities combine their research expertise with the available scientific literature to evaluate those factors which contribute to the addictive qualities of drugs. Specific chapters highlight the positive and negative reinforcement qualities that make drugs rewarding, focus on the two major subtypes of alcoholics, and cover the neuroanatomical and neurochemical bases of psychological dependence, the greatest contributing factor to drug addiction. An essential new resource for scientists, clinicians, and administrators, Addiction Potential of Abused Drugs and Drug Classes also highlights those areas where more work is needed in order to understand how individual drugs affect the processes of dependence, tolerance, and addiction, so that adequate treatment of these disorders can be discovered. The book was written for teachers and researchers in the chemical dependency field, to provide an up-to-date review of the literature. In addition, physicians, nurses, and pharmacists will find the book to be valuable as an update on the relative addiction strengths of abused drugs. Finally, treatment counselors and professionals with some knowledge of physiology and pharmacology will be interested in the book because of its relevance to the clinical treatment of chemically-dependent patients.
Author : Committee on Problems of Drug Dependence (U.S.)
Publisher : Unknown
Page : 172 pages
File Size : 40,9 Mb
Release : 1984
Category : Drug abuse
ISBN : UCR:31210023566811
Author : Mariam W. Fischman,Nancy K. Mello
Publisher : Unknown
Page : 398 pages
File Size : 43,5 Mb
Release : 1989
Category : Electronic
ISBN : OCLC:807215009
Author : Institute of Medicine,Committee on Opportunities in Drug Abuse Research
Publisher : National Academies Press
Page : 330 pages
File Size : 44,7 Mb
Release : 1996-11-01
Category : Medical
ISBN : 9780309055338
Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
Author : Geraline C. Lin,Lynda Erinoff
Publisher : DIANE Publishing
Page : 258 pages
File Size : 51,8 Mb
Release : 1996-07
Category : Anabolic steroids
ISBN : 9780788129698
Addresses the question of whether or not anabolic steroids in themselves possess abuse potential or if they simply play a role in the abuse of other substances. A historical overview of the discovery and development of the drug is provided, plus an evaluation of the drug's performance-enhancing effects. Health risks associated with the abuse of anabolic steroids are covered along with the biological reasons why steroids affect the body the way they do. Behavioral effects are also discussed. Charts, graphs and diagrams.
Author : Mariam W. Fischman,Nancy K. Mello
Publisher : Unknown
Page : 398 pages
File Size : 42,7 Mb
Release : 1989
Category : Electronic
ISBN : OCLC:807215009
Author : College on Problems of Drug Dependence (U.S.). Scientific Meeting
Publisher : Unknown
Page : 484 pages
File Size : 43,7 Mb
Release : 1997
Category : Drug abuse
ISBN : IND:30000130069259
Author : World Health Organization
Publisher : World Health Organization
Page : 60 pages
File Size : 51,7 Mb
Release : 2019-03-04
Category : Law
ISBN : 9789241210225
This report presents the recommendations of the fortieth WHO Expert Committee on Drug Dependence (ECDD). The ECDD is responsible for the assessment of psychoactive substances for possible scheduling under the International Drug Control Conventions. The ECDD reviews the therapeutic usefulness, the liability for abuse and dependence, and the public health and social harm of each substance. The ECDD will advise the Director-General of WHO, to schedule or to amend the scheduling status of a substance. The Director-General will, as appropriate, communicate the recommendations to the Secretary-General of the United Nations, who will in turn communicate the advice to the Commission on Narcotic Drugs (CND).
Author : Committee on Problems of Drug Dependence (U.S.). Scientific Meeting
Publisher : Unknown
Page : 172 pages
File Size : 49,6 Mb
Release : 1984
Category : Drug abuse
ISBN : UOM:39015037506204
Author : Anonim
Publisher : Unknown
Page : 460 pages
File Size : 41,8 Mb
Release : 1976
Category : Drug abuse
ISBN : COLUMBIA:HR01752804
