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Author : Anonim
Publisher : Academic Press
Page : 353 pages
File Size : 42,5 Mb
Release : 1991-12-02
Category : Science
ISBN : 008086564X
The Alkaloids: Chemistry and Pharmacology
Author : Arnold Brossi,Richard Helmuth Fred Manske
Publisher : Unknown
Page : 360 pages
File Size : 54,9 Mb
Release : 1988-07-01
Category : Science
ISBN : 0124695337
Author : Richard Helmuth Fred Manske,R. G. A. Rodrigo
Publisher : Unknown
Page : 611 pages
File Size : 47,9 Mb
Release : 1979
Category : Alkaloids
ISBN : 0124695175
Author : Geoffrey A. Cordell
Publisher : Academic Press
Page : 378 pages
File Size : 42,9 Mb
Release : 2002-12-18
Category : Science
ISBN : 0124695582
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R. H. F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, and various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. This, the 58th volume in the series presents two quite different aspects of alkaloids. The first of the two chapters reviews the substantial progress made on the biotransformations of various classes of alkaloids and examines the enzymes systems involved in this process. Such studies are proving very important in the consideration of how alkaloids can be used in the future as medicinal or biological agents. The second chapter presents a comprehensive review of the known polyamine alkaloids based on their biogenesis and additionally provides overviews of their detailed structural analysis, their synthesis, biosynthesis and biology.
Author : Anonim
Publisher : Academic Press
Page : 405 pages
File Size : 41,5 Mb
Release : 1997-07-23
Category : Science
ISBN : 0080865739
Internationally acclaimed for more than 40 years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all naturalproduct chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile. Indispensable reference work written by leading experts in the field Provides up-to-date, timely reviews on compounds and classes of great interest Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation An essential research tool for anyone working with alkaloids from a chemical or biological perspectiveperspective
Author : R. H. F. Manske
Publisher : Elsevier
Page : 398 pages
File Size : 53,8 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9781483221922
The Alkaloids: Chemistry and Physiology, Volume V: Pharmacology deals with the chemistry and pharmacology of the alkaloids. This book discusses the general pharmacology of morphine, cryptopine-like compounds, toad poisons, and respiratory stimulants. The appraisal of the utility of alkaloids as antimalarials, uterine stimulants, metabolism of cocaine, and optical isomerism-activity relationship are also elaborated. This publication likewise covers the parasympathetic blocking agents as mydriatics, methods of measuring mydriatic activity, alkaloids exhibiting curariform activity, and minor alkaloids of unknown structure. Other topics include the fate of morphine, tropane group, factors affecting cocaine anesthesia, and sympathomimetic mydriatics. This volume is intended for chemists and pharmacologists concerned with alkaloids.
Author : Maurice Shamma
Publisher : Elsevier
Page : 615 pages
File Size : 51,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323144506
The Isoquinoline Alkaloids: Chemistry and Pharmacology presents an overview of the chemistry, biogenesis, spectroscopy, and pharmacology of the isoquinoline alkaloids. This book examines the significant and interesting aspects of alkaloids. Organized into 32 chapters, this book starts with a discussion of the biogenesis of the isoquinolines and the various pharmacological effects of simple tetrahydroisoquinolines that have stimulant and convulsive properties. This text then explores the infrared absorptions, with emphasis on wavelength and frequency. Other chapters include topics on synthesis, degradation, reactions, absolute configuration, as well as on ultraviolet and nuclear magnetic resonance spectroscopy. This book further explores the various methods available for the preparation of simple tetrahydroisoquinolines, including the Bischler–Napieralski, Pictet–Spengler, and phenolic cyclization, as well as the Friedel–Crafts acylation. The last chapter deals with ancistrocladine, which is the first isoquinoline alkaloid found to possess a methyl group. Biochemists and biophysicists will find this book useful.
Author : Anonim
Publisher : Academic Press
Page : 330 pages
File Size : 41,8 Mb
Release : 2019-03-05
Category : Science
ISBN : 9780128174821
The Alkaloids, Volume 82 is the newest release in a series that has covered the topic for more than 60 years. As the esteemed, leading reference in the field of alkaloid chemistry, this series covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections are presented as high-quality, timeless reviews written by renowned experts in the field, with this new release focusing on Recent Progress in the Chemistry of Pandanus Alkaloids, Alkaloids - Derivatives and Applications, Alkaloids of the Lauraceae, and more. Provides the latest information on the study of alkaloids Covers their chemistry, biology, pharmacology and medical applications Contains more than 70 published volumes in this interesting field of study
Author : Geoffrey A. Cordell
Publisher : Academic Press
Page : 301 pages
File Size : 52,7 Mb
Release : 1993-03-01
Category : Alkaloids
ISBN : 0124695434
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R. H. F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, and various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. This, the 58th volume in the series presents two quite different aspects of alkaloids. The first of the two chapters reviews the substantial progress made on the biotransformations of various classes of alkaloids and examines the enzymes systems involved in this process. Such studies are proving very important in the consideration of how alkaloids can be used in thefuture as medicinal or biological agents. The second chapter presents a comprehensive review of the known polyamine alkaloids based on their biogenesis and additionally provides overviews of their detailed structural analysis, their synthesis, biosynthesis and biology. * The 58th volume in this series of essential reference works * Written by leading experts in the field * An essential research tool for anyone working with alkaloids in chemistry or biology
Author : S. William Pelletier
Publisher : Springer Science & Business Media
Page : 378 pages
File Size : 49,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461229087
Volume 8 of this series presents four timely reviews on alkaloids: Chapter 1 is a magnificent and monumental review of curare, "a group of dart and/or arrow poisons varying in composition and featuring muscle relaxation as their basic pharmacological action." The fascinating history of curare is recounted, beginning with early encounters by the Spanish Conquistadores through its use as arrow poisons by the forest tribes in hunting and warfare, its chemistry, ethnography, botany and pharmacology. A terminal section of this chapter treats the development of modern muscle relaxants. This chapter thus traces how curare-initially only a crude plant extract-has given rise to the widely used and very important neuromuscular blocking agents of today. The precise role of plant secondary metabolites and their interactions with insect herbivores have been focal points for research by chemists, botanists and entomologists for many years. Alkaloids and their glycosides are frequently involved as feeding deterrents. Chapter 2 treats the relationships between the chemistry of alkaloids in host plants and the effects that these compounds may have on insect herbivores. Interestingly, an alkaloid produced by a plant may manifest different effects on different insects.
Author : Anonim
Publisher : Academic Press
Page : 528 pages
File Size : 51,5 Mb
Release : 2016-01-08
Category : Science
ISBN : 0128034432
For more than 60 years, The Alkaloids has been the leading book series in the field of alkaloid chemistry. In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered in high-quality timeless reviews written by renowned experts in the field. The Alkaloids is the leading book series in the field of alkaloid chemistry In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered
Author : Shinji Funayama,Geoffrey A. Cordell
Publisher : Elsevier
Page : 295 pages
File Size : 51,5 Mb
Release : 2014-10-21
Category : Science
ISBN : 9780124173149
Alkaloids are a large group of structurally complex natural products displaying a wide range of biological activities. The purpose of Alkaloids: A Treasury of Poisons and Medicines is to classify, for the first time, the alkaloids isolated from the natural sources until now. The book classifies all of the alkaloids by their biosynthetic origins. Of interest to the organic chemistry and medicinal chemistry communities involved in drug discovery and development, this book describes many alkaloids isolated from the medicinal plants, including those used in Japanese Kampo medicine. Classifies and lists alkaloids from natural sources Occurrence and biosynthetic pathways of alkaloids Indicates key uses and bioactivity of alkaloids
Author : S.W. Pelletier
Publisher : Elsevier
Page : 392 pages
File Size : 40,6 Mb
Release : 1996-12-12
Category : Science
ISBN : 0080527000
Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the Thalictrum alkaloids. Forty-six new alkaloids are described from fifteen species of the genus Thalictrum, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the Thalictrum alkaloids. Chapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: Taxus). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine. Chapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized. Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related nortropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing. Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.
Author : Anonim
Publisher : Elsevier
Page : 415 pages
File Size : 43,6 Mb
Release : 2003-10-13
Category : Science
ISBN : 9780080521497
This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective Comprehensive dynamic reviews written by the leading authors in the respective fields Broader coverage than before on the biological aspects
Author : Robert B. Raffa
Publisher : CRC Press
Page : 356 pages
File Size : 49,9 Mb
Release : 2014-10-29
Category : Medical
ISBN : 9781482225198
Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature's only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds-those derived from the plant Mitragyna speciosa. This plan
