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The Art of Theoretical Biology by Franziska Matthäus,Sebastian Matthäus,Sarah Harris,Thomas Hillen Pdf
This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision.
Theoretical Biology and Complexity by Robert J. Rosen Pdf
Theoretical Biology and Complexity: Three Essays on the Natural Philosophy of Complex Systems is made up of three short essays—each separately conceived and written, each with distinct thrusts and emphases, but nevertheless closely related in substance and spirit. All three spring from a common concern: to grasp and comprehend the material basis of living systems. The first essay is about the interaction between particles and the consequent observable manifestations. It casts the analysis of the measurement process into an elegant dualism relating modes of description, and explores the consequences of this dualism for what may be called classical physics. The second essay explores the deeper consequences of representing the properties of natural systems through states built up out of observable quantities, and the dynamics that such systems impose on each other through interactions. The final essay argues that traditional modes of system representation, involving fixed sets of states together with imposed dynamical laws, strictly pertains only to an extremely limited class of systems (called simple systems or mechanisms). Systems not in this class are called “complex, and these can only be in some sense approximated, locally and temporally, by simple ones. Such a radical alteration of viewpoint leads to a large number of concrete, practical consequences, some of which are described in the essay.
Quantitative Biology by Brian Munsky,William S. Hlavacek,Lev S. Tsimring Pdf
An introduction to the quantitative modeling of biological processes, presenting modeling approaches, methodology, practical algorithms, software tools, and examples of current research. The quantitative modeling of biological processes promises to expand biological research from a science of observation and discovery to one of rigorous prediction and quantitative analysis. The rapidly growing field of quantitative biology seeks to use biology's emerging technological and computational capabilities to model biological processes. This textbook offers an introduction to the theory, methods, and tools of quantitative biology. The book first introduces the foundations of biological modeling, focusing on some of the most widely used formalisms. It then presents essential methodology for model-guided analyses of biological data, covering such methods as network reconstruction, uncertainty quantification, and experimental design; practical algorithms and software packages for modeling biological systems; and specific examples of current quantitative biology research and related specialized methods. Most chapters offer problems, progressing from simple to complex, that test the reader's mastery of such key techniques as deterministic and stochastic simulations and data analysis. Many chapters include snippets of code that can be used to recreate analyses and generate figures related to the text. Examples are presented in the three popular computing languages: Matlab, R, and Python. A variety of online resources supplement the the text. The editors are long-time organizers of the Annual q-bio Summer School, which was founded in 2007. Through the school, the editors have helped to train more than 400 visiting students in Los Alamos, NM, Santa Fe, NM, San Diego, CA, Albuquerque, NM, and Fort Collins, CO. This book is inspired by the school's curricula, and most of the contributors have participated in the school as students, lecturers, or both. Contributors John H. Abel, Roberto Bertolusso, Daniela Besozzi, Michael L. Blinov, Clive G. Bowsher, Fiona A. Chandra, Paolo Cazzaniga, Bryan C. Daniels, Bernie J. Daigle, Jr., Maciej Dobrzynski, Jonathan P. Doye, Brian Drawert, Sean Fancer, Gareth W. Fearnley, Dirk Fey, Zachary Fox, Ramon Grima, Andreas Hellander, Stefan Hellander, David Hofmann, Damian Hernandez, William S. Hlavacek, Jianjun Huang, Tomasz Jetka, Dongya Jia, Mohit Kumar Jolly, Boris N. Kholodenko, Markek Kimmel, Michał Komorowski, Ganhui Lan, Heeseob Lee, Herbert Levine, Leslie M Loew, Jason G. Lomnitz, Ard A. Louis, Grant Lythe, Carmen Molina-París, Ion I. Moraru, Andrew Mugler, Brian Munsky, Joe Natale, Ilya Nemenman, Karol Nienałtowski, Marco S. Nobile, Maria Nowicka, Sarah Olson, Alan S. Perelson, Linda R. Petzold, Sreenivasan Ponnambalam, Arya Pourzanjani, Ruy M. Ribeiro, William Raymond, William Raymond, Herbert M. Sauro, Michael A. Savageau, Abhyudai Singh, James C. Schaff, Boris M. Slepchenko, Thomas R. Sokolowski, Petr Šulc, Andrea Tangherloni, Pieter Rein ten Wolde, Philipp Thomas, Karen Tkach Tuzman, Lev S. Tsimring, Dan Vasilescu, Margaritis Voliotis, Lisa Weber
This book surveys the state of the art in theoretical and computer modeling for biological sciences. Using both mathematical and stochastic computer models of biological systems, the author focuses in particular on three central topics: the origin of life, the immune system, and memory in the brain. Throughout the book, the author emphasizes how the power of modern computers is allowing researchers in theoretical biology to break free of the constraints on modeling that were imposed by the traditional differential equation approach. Unique in its emphasis on modeling and computer simulation, Theoretical Models in Biology: The Origin of Life, the Immune System, and the Brain will be welcomed by students and researchers of mathematical biology.
National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century Publisher : National Academies Press Page : 208 pages File Size : 54,7 Mb Release : 2008-01-22 Category : Science ISBN : 9780309134170
The Role of Theory in Advancing 21st-Century Biology by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Defining and Advancing the Conceptual Basis of Biological Sciences in the 21st Century Pdf
Although its importance is not always recognized, theory is an integral part of all biological research. Biologists' theoretical and conceptual frameworks inform every step of their research, affecting what experiments they do, what techniques and technologies they develop and use, and how they interpret their data. By examining how theory can help biologists answer questions like "What are the engineering principles of life?" or "How do cells really work?" the report shows how theory synthesizes biological knowledge from the molecular level to the level of whole ecosystems. The book concludes that theory is already an inextricable thread running throughout the practice of biology; but that explicitly giving theory equal status with other components of biological research could help catalyze transformative research that will lead to creative, dynamic, and innovative advances in our understanding of life.
Sketching Theoretical Biology by C. H. Waddington Pdf
The purpose of this volume is to bring together a number of elements that would be useful in the construction of a coherent and comprehensive theory of biology. Based on the assumption that living systems represent some kind of "organized complexity," the collection discusses meaningful ways of formulating two basic questions: what is the nature of this complexity; and, what are the principles of its organization? The question always asked about biological theory is whether or not it constitutes useful scientific theory. Because many useful biological theories cannot yet be made explicit in terms of conventional physics, Sketching Theoretical Biology illustrates the types of questions in biology that correspond to the types of issues discussed in theoretical physics. This book, originally published in 1969, centers around a vigorous debate on the role played by metaphysical beliefs in determining scientific attitudes. The discussion covers heredity and evolution, cognitive processes and control processes, general property of hierarchies, and the current status of neo-Darwinism. Contributors include theoretical physicists, philosophers, neuroscientists, theoretical chemists, computer scientists, chemical engineers, geneticists and molecular biologists.
Theoretical biology is still in its early stages as an academic discipline. There is even little agreement as to what topics it should deal with or in what manner it should precede; and it is only recently that philosophers felt called upon to notice the relevance of biological topics as evolution or perception to their traditional problems. This work is a publication of the International Union of Biological Sciences, the central organization of all the branches of biology. The main focus here is to explore the possibility of formulating some frame of concepts and methods around which theoretical biology can grow. The intention of this collective effort was that discussions would be concerned, not with the theory of particular biological processes, such as membrane permeability, genetics, and neural activity, but rather with an attempt to discover and formulate general concepts and logical relations characteristic of living as contrasted with inorganic systems. Further, this project is a consideration of implications these might have for general philosophy. Many well-known scientists contributed to this volume, such as J. Maynard Smith, Ernst Mayr, Brian Goodwin, and Renà Thom. The Origin of Life: Toward a Theoretical Biology explores the character of the problems facing any theory of general biology. It contains a series of chapters and exchanges discussing such topics as the origin of life, cellular differentiation, morphogensis, evolution, and indeterminacy in biological and physical systems, the organization of the brain, the statistical mechanics of non-linear oscillators, and many other topics. This is a pioneering volume by recognized leaders in an emerging fieldâthe first of four such works.
Current Themes in Theoretical Biology by Thomas A.C. Reydon,Lia Hemerik Pdf
This book originated as a Festschrift to mark the publication of Volume 50 of the journal `Acta Biotheoretica' in 2002 and the journal’s 70th anniversary in 2005. In it, eleven previously unpublished research papers have been collected that reflect the entire scope of topics on which `Acta Biotheoretica' publishes. `Acta Biotheoretica' is a journal on theoretical biology, published by Kluwer Academic Publishers, that has its roots in the Dutch tradition of theoretical biology. From the perspective of this tradition, theoretical biology is understood as encompassing a broad spectrum of disciplines ranging from mathematical biology to philosophy of biology. To reflect the Dutch roots of the journal, all papers have been invited from authors that work in The Netherlands. This book is aimed at an audience of theoretical and mathematical biologists, philosophers of biology and philosophers of science, and biologists in general.
The Routledge Companion to Biology in Art and Architecture by Charissa Terranova,Meredith Tromble Pdf
The Routledge Companion to Biology in Art and Architecture collects thirty essays from a transdisciplinary array of experts on biology in art and architecture. The book presents a diversity of hybrid art-and-science thinking, revealing how science and culture are interwoven. The book situates bioart and bioarchitecture within an expanded field of biology in art, architecture, and design. It proposes an emergent field of biocreativity and outlines its historical and theoretical foundations from the perspective of artists, architects, designers, scientists, historians, and theoreticians. Includes over 150 black and white images.
Theoretical Biology by Jakob Von 1864-1944 Uexküll,Doris L (Doris Livingston) MacKinnon Pdf
This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Foundations of Mathematical Biology by Robert J. Rosen Pdf
Foundations of Mathematical Biology, Volume III, is devoted to the treatment of behavior of whole organisms and groups of organisms. The viewpoint taken throughout the book is a holistic, phenomenological one. That is, the integrated behavior of these organisms and groups of organisms is not, in general, referred back to specific structural properties of interacting subunits (as in a reductionist scheme), but is rather treated on its own terms without invoking the properties of lower levels of organization. The book begins with an overview of organization and control in physiological systems, with emphasis on the mathematical techniques involved in more detailed investigations of specific physiological mechanisms. Separate chapters cover the cardiovascular system, with particular reference to blood flow; gross problems of organic form; a relational overview of physics, biology, and sociology; the automata theory in the context of the central nervous system; and populations of interacting organisms. The final chapter discusses the material presented in the entire work, some of its philosophical presuppositions and implications, and the possibility of constructing a unified theory of mathematical biology.
Sketching Theoretical Biology by Wilhelmina A. Leigh Pdf
The purpose of this volume is to bring together a number of elements that would be useful in the construction of a coherent and comprehensive theory of biology. Based on the assumption that living systems represent some kind of "organized complexity," the collection discusses meaningful ways of formulating two basic questions: what is the nature of this complexity; and, what are the principles of its organization? The question always asked about biological theory is whether or not it constitutes useful scientific theory. Because many useful biological theories cannot yet be made explicit in terms of conventional physics, Sketching Theoretical Biology illustrates the types of questions in biology that correspond to the types of issues discussed in theoretical physics. This book, originally published in 1969, centers around a vigorous debate on the role played by metaphysical beliefs in determining scientific attitudes. The discussion covers heredity and evolution, cognitive processes and control processes, general property of hierarchies, and the current status of neo-Darwinism. Contributors include theoretical physicists, philosophers, neuroscientists, theoretical chemists, computer scientists, chemical engineers, geneticists and molecular biologists.
