The Cerebellum Epilepsy And Behavior

Author : Irving Cooper
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461345084

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The Cerebellum, Epilepsy, and Behavior by Irving Cooper Pdf

In cats anesthetized lightly with pentobarbital or alpha-chloralose, electrical stimulation of the paramedian lobule of cerebellum resulted in a change of EEG pattern. Prior to stimulation the pattern consisted of h igh-ampl itude slow waves with superimposed low-ampl itude fast activity. In addition, the EEGs of animals anesthetized with chloralose showed "chloralose spikes". Immediately following brief cerebellar stimulation the slow wave activity and spikes disappeared, leaving only low-voltage fast activity. The effect was most pronounced in the contralateral leads from the rostral portions of the cerebrum. Study of the parameters most effective in evoking this effect revealed that stimulation frequency, train duration, and probably pulse duration affected the duration of suppression in a sigmoid fashion, with inflection points at approximately 90 Hz, 2.5 sec, and 1 msec, respectively. Above threshold values, stimulation cur rent showed an approximately linear relationship to duration of EEG sup pression. The after-discharge resulting from focal electrical stimulation of the cerebral cortex could be shortened by electrical stimulation of the para median lobule. The effect was essentially the same when cerebellar stim ulation preceded, occurred during, or followed the cerebral cortical stim ulation. The great variability of the after-discharge resulting from cerebral cortical stimulation as well as the variability of the effects of cerebellar stimulation made it impractical to study systematically the parameters op timal for shorten ing after-discharge. Such a study wi II require use of an awake, preferably partially restrained animal with electrodes chronically implanted.

Author : Irving Spencer Copper
Publisher : Unknown
Page : 128 pages
File Size : 47,5 Mb
Release : 1974
Category : Electronic
ISBN : OCLC:610747271

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The Cerebellum, Epilepsy and Behavior by Irving Spencer Copper Pdf

Author : Gregory L. Holmes, MD,Steven C. Schachter,Dr. Dorothee GA Kasteleijn-Nolst Trenite, "MD,MPH"
Publisher : Demos Medical Publishing
Page : 264 pages
File Size : 52,8 Mb
Release : 2007-10-15
Category : Medical
ISBN : 1934559881

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Behavioral Aspects of Epilepsy by Gregory L. Holmes, MD,Steven C. Schachter,Dr. Dorothee GA Kasteleijn-Nolst Trenite, "MD,MPH" Pdf

The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of episodes and what can be determined from the number of seizures. With contributions by dozens of leading international experts, this is the only book to cover all aspects of this critical emerging science. Adult and pediatric patients, animal models, and epilepsy surgery and its effects are all covered in detail. Behavioral Aspects of Epilepsy is the only source for up-to-date information on a topic that has significant and growing interest in the medical community. This comprehensive, authoritative text has a bench to bedside, approach that covers: The mechanisms underlying epilepsy and behavior Neurophysiologic function Neuropsychiatric and behavioral disorders in patients with epilepsy The effects of treatments and surgery on behavior Pediatric and adolescent epilepsy Disorders associated with epilepsy that impact behavior And much more

Author : Jeffrey L. Noebels,Massimo Avoli
Publisher : OUP USA
Page : 1258 pages
File Size : 41,7 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780199746545

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Jasper's Basic Mechanisms of the Epilepsies by Jeffrey L. Noebels,Massimo Avoli Pdf

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Author : Marco Mula
Publisher : Academic Press
Page : 413 pages
File Size : 55,7 Mb
Release : 2019-04-20
Category : Medical
ISBN : 9780128148785

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The Comorbidities of Epilepsy by Marco Mula Pdf

Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

Author : Jerome Engel Jr
Publisher : Oxford University Press
Page : 737 pages
File Size : 46,8 Mb
Release : 2013-01-31
Category : Medical
ISBN : 9780195328547

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Seizures and Epilepsy by Jerome Engel Jr Pdf

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Author : J. Kiffin Penry
Publisher : Unknown
Page : 1424 pages
File Size : 52,9 Mb
Release : 1978
Category : Epilepsy
ISBN : SRLF:D0002780039

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Indexes to the Epilepsy Accessions of the Epilepsy Information System by J. Kiffin Penry Pdf

Author : National Academy of Sciences,Institute of Medicine,Sandra Ackerman
Publisher : National Academies Press
Page : 195 pages
File Size : 44,6 Mb
Release : 1992-01-01
Category : Medical
ISBN : 9780309045292

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Discovering the Brain by National Academy of Sciences,Institute of Medicine,Sandra Ackerman Pdf

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Author : Anonim
Publisher : Academic Press
Page : 709 pages
File Size : 48,9 Mb
Release : 1997-10-02
Category : Science
ISBN : 9780080857756

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The Cerebellum and Cognition by Anonim Pdf

The Cerebellum and Cognition pulls together a preeminent group of authors. The cerebellum has been previously considered as a highly complex structure involved only with motor control. The cerebellum is essential to nonmotor functions, and recent research has revealed new medically important roles of the cerebellum and cognitive processes. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Comprehensive coverage of cerebellum in motor control and cognition New developments regarding the cerebellum and motor systems Therapeutic implications of cerebellar contributions to cognition Preeminent group of contributors

Author : David B. Arciniegas,C. Alan Anderson,Christopher M. Filley
Publisher : Cambridge University Press
Page : 685 pages
File Size : 50,7 Mb
Release : 2013-01-24
Category : Medical
ISBN : 9781139619158

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Behavioral Neurology & Neuropsychiatry by David B. Arciniegas,C. Alan Anderson,Christopher M. Filley Pdf

The merger of behavioral neurology and neuropsychiatry into a single medical subspecialty, Behavioral Neurology & Neuropsychiatry, requires an understanding of brain-behavior relationships and a clinical approach that transcends the traditional perspectives of neurology and psychiatry. Designed as a primer of concepts and principles, and authored by a multidisciplinary group of internationally known clinical neuroscientists, this book divides into three sections: • Structural and Functional Neuroanatomy (Section I) addresses the neuroanatomy and phenomenology of cognition, emotion, and behavior • Clinical Assessment (Section II) describes neuropsychiatric history taking, neurological and mental status examinations, neuropsychological assessment, and neuroimaging, electrophysiologic, and laboratory methods • Treatment (Section III) discusses environmental, behavioral, rehabilitative, psychological, social, pharmacological, and procedural interventions for cognitive, emotional, and behavioral disorders. By emphasizing the principles of Behavioral Neurology & Neuropsychiatry, this book will improve your understanding of brain-behavior relationships and inform your care of patients and families affected by neurobehavioral disorders.

Author : Hans O. Lüders
Publisher : CRC Press
Page : 396 pages
File Size : 51,7 Mb
Release : 2020-08-26
Category : Medical
ISBN : 9781000148954

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Deep Brain Stimulation and Epilepsy by Hans O. Lüders Pdf

Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.

Author : Hendrik Keyzer,George M. Eckert,Felix Gutmann
Publisher : CRC Press
Page : 432 pages
File Size : 42,9 Mb
Release : 1990-09-25
Category : Medical
ISBN : 0849354099

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Electropharmacology by Hendrik Keyzer,George M. Eckert,Felix Gutmann Pdf

This extraordinary book covers the extremely broad subject of electropharmacology-defined here as the application of principles and methods of electrochemistry to biological topics associated with the action of drugs. It focuses on the physical principles of the movement of electrical charges across interfaces in pharmacological phenomena. It also covers drugs and the electrical procedures which modify a natural process having an electrochemical basis or component. This outstanding report studies the pharmacologically important properties and effects by electrochemical methods, the electrochemical alternatives or adjuncts to drug therapy, and the pharmacology involved. Easy to read and understand, this is an ideal reference for all researchers and practitioners of pharmacology and related fields.

Author : Simon Shorvon,Renzo Guerrini,Eugen Trinka,Steven Schachter
Publisher : Cambridge University Press
Page : 1013 pages
File Size : 52,6 Mb
Release : 2019-05-02
Category : Medical
ISBN : 9781108420754

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The Causes of Epilepsy by Simon Shorvon,Renzo Guerrini,Eugen Trinka,Steven Schachter Pdf

Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Author : Ahmed A. Moustafa
Publisher : John Wiley & Sons
Page : 586 pages
File Size : 47,6 Mb
Release : 2017-11-13
Category : Psychology
ISBN : 9781119159063

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Computational Models of Brain and Behavior by Ahmed A. Moustafa Pdf

A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
Page : 570 pages
File Size : 43,5 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015062497741

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The Epilepsies by Chrysostomos P. Panayiotopoulos Pdf

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.