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Author : Peter Sheldon (MD.)
Publisher : Unknown
Page : 286 pages
File Size : 54,7 Mb
Release : 2007
Category : Aspirin
ISBN : OCLC:1285558050
Author : Peter Sheldon
Publisher : Unknown
Page : 316 pages
File Size : 51,5 Mb
Release : 2007
Category : Health & Fitness
ISBN : STANFORD:36105124062204
The author has long been interested in how plant derived substances can prove beneficial to Medicine. Writings on papyrus from the earliest times have described the use of willow bark for soothing inflamed wounds. Major contributions by the Reverend Edward Stone of Chipping Norton, and Dr. Thomas Maclagan of Dundee are covered, along with the unique discovery by Professor John Vane and his team, of the fundamental effect of aspirin on prostaglandin synthesis. The book includes fascinating memorabilia on the early days of aspirin, kindly donated from the Bayer archive.In his first book on the foxglove, the author described how Nature's gift of digitalis came to become accepted worldwide as a valuable treatment for heart failure. Now, he has explored the bark of the willow, from which by chemical modification, aspirin was obtained. But whereas up to now, digitalis (in its current form, digoxin), only has a place in the treatment of heart disease, aspirin ? the world's most ubiquitous pain killer, has in the last half-century, been shown also to prevent heart attacks and strokes. And in addition it may soon come into use in cancer prevention.The author is currently a practising consultant rheumatologist at Leicester Royal Infirmary who, in former years, prescribed prodigious amounts of aspirin for the treatment of rheumatoid arthritis. As an immunologist at the University of Leicester, he has taught medical students from the inception of its medical school.
Author : Diarmuid Jeffreys
Publisher : Bloomsbury Publishing USA
Page : 352 pages
File Size : 46,8 Mb
Release : 2008-12-01
Category : Medical
ISBN : 9781596918160
Diarmuid Jeffreys traces the story of aspirin from the drug's origins in ancient Egypt, through its industrial development at the end of the nineteenth century and its key role in the great flu pandemic of 1918, to its subsequent exploitation by the pharmaceutical conglomerates and the marvelous powers still being discovered today. Diarmuid Jeffreys is a British writer, journalist, and television producer who has made current affairs and documentary programs for BBC TV, Channel 4, and others. He is also the author of The Bureau: Inside the Modern FBI. He lives with his wife and children in East Sussex. A San Francisco Chronicle Best Book of 2004 "Jeffreys is an extremely clever and accessible writer, and his book is comprehensible while still being smart. If it is possible to get giddy over aspirin, Jeffreys manages it. This enthusiasm injects his well-researched prose with a verve and drama that makes for something of a medical history page-turner."-Oregonian "A remarkable story...This is more than the story of aspirin: It is a history lesson."-San Diego Union-Tribune "Diarmuid Jeffreys seamlessly manages his complicated subject...Throughout, Jeffreys renders an absorbing account of the drug's ride from obscurity to celebrity and around about again to its rebirth as today's wonder drug."-San Francisco Chronicle "One of the most fascinating stories in the whole of medicine."-New Scientist Also available: HC 1-58234-386-1 ISBN 978-158234-386-0 $25.95
Author : Mark A. Largent
Publisher : Bellevue Literary Press
Page : 288 pages
File Size : 43,9 Mb
Release : 2015-01-19
Category : Medical
ISBN : 9781934137895
“A fascinating history of a public health crisis. Compellingly written and insightful, Keep Out of Reach of Children traces the discovery of Reye’s syndrome, research into its causes, industry’s efforts to avoid warning labels on one suspected cause, aspirin, and the feared disease’s sudden disappearance. Largent’s empathy is with the myriad children and parents harmed by the disease, while he challenges the triumphalist view that labeling solved the crisis.” —ERIK M. CONWAY, coauthor of Merchants of Doubt “Largent’s engaging and honest account explores how medical mysteries are shaped by prevailing narratives about venal drug companies, heroic investigators, and Johnny-come-lately politicians.” —HELEN EPSTEIN, author of The Invisible Cure “Fascinating. . . . Thought-provoking.” —Booklist “Well-researched. . . . A revealing work.” —Kirkus Reviews Reye’s syndrome, identified in 1963, was a debilitating, rare condition that typically afflicted healthy children just emerging from the flu or other minor illnesses. It began with vomiting, followed by confusion, coma, and in 50 percent of all cases, death. Survivors were often left with permanent liver or brain damage. Desperate, terrorized parents and doctors pursued dramatic, often ineffectual treatments. For over fifteen years, many inconclusive theories were posited as to its causes. The Centers for Disease Control dispatched its Epidemic Intelligence Service to investigate, culminating in a study that suggested a link to aspirin. Congress held hearings at which parents, researchers, and pharmaceutical executives testified. The result was a warning to parents and doctors to avoid pediatric use of aspirin, leading to the widespread substitution of alternative fever and pain reducers. But before a true cause was definitively established, Reye’s syndrome simply vanished. A harrowing medical mystery, Keep Out of Reach of Children is the first and only book to chart the history of Reye’s syndrome and reveal the confluence of scientific and social forces that determined the public health policy response, for better or for ill. Mark A. Largent, a survivor of Reye’s syndrome, is the author of Vaccine: The Debate in Modern America and Breeding Contempt: The History of Coerced Sterilization in the United States. He is a historian of science, Associate Professor in James Madison College at Michigan State University, and Associate Dean in Lyman Briggs College at Michigan State University. He lives in Lansing, Michigan.
Author : Simon Cotton
Publisher : CRC Press
Page : 280 pages
File Size : 53,6 Mb
Release : 2011-11-16
Category : Medical
ISBN : 9781439807743
From cooking to medicine, from engineering to art, chemistry—the science of molecules—is everywhere. A celebration of the molecules of chemistry, Every Molecule Tells a Story celebrates the molecules responsible for the experiences of everyday life: the air we breathe; the water we drink; the chemicals that fuel our living; the steroids that give us sex; the colours of the seasons; the drugs that heal us; and the scented molecules that enrich our diet and our encounters with each other. You can’t see them, but you know that they are there. Unveiling the structures of poisonous "natural" substances and beneficial man-made molecules, this book brushes away any preconceived notions about chemistry to demonstrate why and how molecules matter.
Author : Johann A. Fuchs
Publisher : Page Publishing Inc
Page : 1008 pages
File Size : 48,6 Mb
Release : 2019-04-15
Category : Fiction
ISBN : 9781644244890
The story is about an ex-soldier who is called back to the Army for a project that does not involve military matters. Before the project ends, he is sent off to the fighting, returning injured, and loses his wife and finds companionship with another. As the project ends, politicians try to recruit the war hero to run for office. The reluctant war hero is dragged into the presidential race, which he does everything possible to lose, with it ending with a major constitutional crisis.
Author : Alexander Zaitchik
Publisher : Catapult
Page : 305 pages
File Size : 41,8 Mb
Release : 2023-03-28
Category : Business & Economics
ISBN : 9781640095908
For readers of Bad Blood and Empire of Pain, an authoritative look at monopoly medicine from the dawn of patents through the race for COVID-19 vaccines and how the privatization of public science has prioritized profits over people Owning the Sun tells the story of one of the most contentious fights in human history: the legal right to produce lifesaving medicines. Medical science began as a discipline geared toward the betterment of all human life, but the merging of research with intellectual property and the rise of the pharmaceutical industry warped and eventually undermined its ethical foundations. Since World War II, federally funded research has facilitated most major medical breakthroughs, yet these drugs are often wholly controlled by price-gouging corporations with growing international ambitions. Why does the U.S. government fund the development of medical science in the name of the public only to relinquish exclusive rights to drug companies, and how does such a system impoverish us, weaken our responses to crises, and, as in the cases of AIDS and COVID-19, put the world at risk? Outlining how generations of public health and science advocates have attempted to hold the line against Big Pharma and their allies in government, Alexander Zaitchik’s first-of-its-kind history documents the rise of privatized medicine in the United States and its subsequent globalization. From the controversial arrival of patent-wielding German drug firms in the late nineteenth century to present-day coordination between industry and philanthropic organizations—including the influential Bill & Melinda Gates Foundation—that stymie international efforts to vaccinate the world against COVID-19, Owning the Sun tells one of the most important and least understood histories of our time.
Author : Cynthia A Connolly
Publisher : Rutgers University Press
Page : 339 pages
File Size : 53,7 Mb
Release : 2018-05-11
Category : Health & Fitness
ISBN : 9780813575230
Winner of the 2018 Arthur J. Viseltear Award from the Medical Care Section of the American Public Health Association Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance—many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children’s risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable. Open access edition funded by the National Endowment for the Humanities. The text of this book is licensed under a Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Author : Karsten Schrör
Publisher : Walter de Gruyter GmbH & Co KG
Page : 864 pages
File Size : 43,8 Mb
Release : 2022-07-18
Category : Medical
ISBN : 9783110746488
Written by a leading expert on Aspirin-related research, this is the most comprehensive treaty of the history, pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This third completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention and treatment of cardiovascular diseases, thromboinflammation and colorectal cancer.
Author : Paul May,Simon Cotton
Publisher : CRC Press
Page : 746 pages
File Size : 53,5 Mb
Release : 2014-10-23
Category : Science
ISBN : 9781466589605
"This new book is by two knowledgeable and expert popularizers of chemistry and deals exclusively with molecules and compounds rather than with the simpler atoms and elements. It is based on the very successful ‘Molecule of the Month’ website that was begun by Paul May fifteen years ago and to which his co-author Simon Cotton has been a frequent contributor. ... The authors ... strike an excellent balance between introducing the novice to the world of molecules while also keeping the expert chemist interested. ... I highly recommend this book to all readers. It will vastly expand your knowledge and horizons of chemistry and the human ingenuity that surrounds it." —From the Foreword by Dr. Eric Scerri, UCLA, Los Angeles, website: www.ericscerri.com, Author of ‘The Periodic Table, Its Story and Its Significance’ and several other books on the elements and the periodic table. The world is composed of molecules. Some are synthetic while many others are products of nature. Molecules That Amaze Us presents the stories behind many of the most famous and infamous molecules that make up our modern world. Examples include the molecule responsible for the spicy heat in chilies (capsaicin), the world’s first synthetic painkiller (aspirin), the pigment responsible for the color of autumn leaves (carotene), the explosive in dynamite (nitroglycerine), the antimalarial drug (quinine), the drug known as "speed" (methamphetamine), and many others. Other molecules discussed include caffeine, adrenaline, cholesterol, cocaine, digitalis, dopamine, glucose, insulin, methane, nicotine, oxytocin, penicillin, carbon dioxide, limonene, and testosterone. In all, the book includes 67 sections, each describing a different molecule, what it does, how it is made, and why it is so interesting. Written by experts in the field, the book is accessible and easy to read. It includes amusing anecdotes, historical curiosities, and entertaining facts about each molecule, thereby balancing educational content with entertainment. The book is heavily illustrated with relevant photographs, images, and cartoons—the aim being both to educate and entertain.
Author : Charles C. Mann,Mark L. Plummer
Publisher : Knopf Publishing Group
Page : 456 pages
File Size : 41,6 Mb
Release : 1991
Category : Aspirin
ISBN : STANFORD:36105041183950
The history of competition in the aspirin industry.
Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 45,9 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Author : Karsten Schrör
Publisher : John Wiley & Sons
Page : 474 pages
File Size : 45,7 Mb
Release : 2016-09-26
Category : Science
ISBN : 9783527338054
Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.
Author : Glenn Parris
Publisher : Xlibris Corporation
Page : 404 pages
File Size : 55,9 Mb
Release : 2013-05-16
Category : Fiction
ISBN : 9781483633015
This is the story of Anita Thomas and Jack Wheaton, two young doctors unwittingly in possession of a designer antibody for the treatment of fibromyalgia syndrome. The new drug is effective, but dangerously flawed. The problem is Anita Thomas has developed a cheap, safe alternative agent. Naturally, after expenditure of a fortune in development, the drug manufactures are not at all pleased with her. The pieces unfold, as we follow Anita and Jack from beautiful upscale midtown to the seedier downtown counterparts of Boston and Atlanta over shadowed by deadly stalkers and embellished by amorous often comically frustrating misadventures. The Renaissance of Aspirin is peppered with industrial espionage, suspense and passion as the chase is on for the first cure for fibromyalgia. Entangled with colorful comrades such as Dasher Clay; Stormi Seales and Khandi Barr in their camp, Anita and Jack barely keep ahead of the treacherous cabal of nemeses; Luciana Velasquez and Jason Brasil led by the Über-villain, Orson Quirk. Paced in the tradition of The Pelican Brief, Coma or a contemporary Maltese Falcon, The Renaissance of Aspirin is both plot and character driven with a ly credible McGuffin at its core. These complex characters are funny, mean, desperate, lonely and at the same time very humanly imperfect. Readers will find their prickly exploits thoroughly entertaining.
Author : Robert J. Gordon
Publisher : Princeton University Press
Page : 785 pages
File Size : 42,5 Mb
Release : 2017-08-29
Category : Business & Economics
ISBN : 9781400888955
How America's high standard of living came to be and why future growth is under threat In the century after the Civil War, an economic revolution improved the American standard of living in ways previously unimaginable. Electric lighting, indoor plumbing, motor vehicles, air travel, and television transformed households and workplaces. But has that era of unprecedented growth come to an end? Weaving together a vivid narrative, historical anecdotes, and economic analysis, The Rise and Fall of American Growth challenges the view that economic growth will continue unabated, and demonstrates that the life-altering scale of innovations between 1870 and 1970 cannot be repeated. Gordon contends that the nation's productivity growth will be further held back by the headwinds of rising inequality, stagnating education, an aging population, and the rising debt of college students and the federal government, and that we must find new solutions. A critical voice in the most pressing debates of our time, The Rise and Fall of American Growth is at once a tribute to a century of radical change and a harbinger of tougher times to come.
