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DNA by James D. Watson,Andrew Berry,Kevin Davies Pdf
The definitive insider's history of the genetic revolution--significantly updated to reflect the discoveries of the last decade. James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact--practical, social, and ethical--on our society and our world.
"James D. Watson, the Nobel laureate whose pioneering work helped unlock the mystery of DNA's structure, charts the greatest scientific journey of our time, from the discovery of the double helix to today's controversies to what the future may hold. Updated to include new findings in gene editing, epigenetics, agricultural chemistry, as well as two entirely new chapters on personal genomics and cancer research. This is the most comprehensive and authoritative exploration of DNA's impact ... practical, social, and ethical ... on our society and our world" ... Provided by publisher.
The Genetic Revolution and Human Rights by Justine Burley Pdf
Are eugenics practices morally defensible? Who should have access to g enetic information about particular individuals? What dangers for cult ural and racial diversity do developments in genetics pose? And how sh ould scientific research be regulated and by whom? These are some of t he questions addressed in this book, which comprises the 1998 Oxford A mnesty Lectures. The lecturers are all respected in their specific fie ld, including Hilary Putnam, Ian Wilmut (co-creator of 'Dolly' the she ep), and Jonathan Glover. Each lecture is proceeded by a discussion ar ticle written by prominent lawyers, scientists, and philosophers, and a foreword has been written by Richard Dawkins. Fascinating and though t-provoking, this book is essential reading for all those interested i n the future of genetics and humankind.
ect, Philip Kitcher takes readers into the heart of the revolution in genetic research today and raises important philosophical questions about its impact on ethical, legal, and political issues, now and in the future.
What will our lives be like fifty years from now? What will we know about ourselves as humans, and how will that affect our lives? It's impossible to know the future for certain, but one thing we do know—perhaps nothing will alter our future more than the Genetics Revolution of the past thirty-five years. This book clarifies the history and examines the possible impact of five major areas of genetic research: The Human Genome Project and genetic engineering, In vitro fertilization (IVF) and the technology of reproduction, The Human Genome Diversity Project, which is studying the variation of the human genome, Embryonic stem-cell research, Cloning. All of these areas of research produce two reactions among the general public—hope for the improvement of people's lives, and fear of science out of control. The Genetics Revolution examines the scientific, social, and political impacts of the genetics on everyday life—in the past, in the present, and in the future. Each specific topic is contained within its own chapter for ease in accessing specific information. This is an ideal resource for students, teachers, and others preparing research papers. In addition, it integrates science and social science topics in a way that supports topics in the school curricula. The book contains documented, current information that both supports and challenges current thinking about genetics.
Race and the Genetic Revolution by Sheldon Krimsky,Kathleen Sloan Pdf
Do advances in genomic biology create a scientific rationale for long-discredited racial categories? Leading scholars in law, medicine, biology, sociology, history, anthropology, and psychology examine the impact of modern genetics on the concept of race. Contributors trace the interplay between genetics and race in forensic DNA databanks, the biology of intelligence, DNA ancestry markers, and racialized medicine. Each essay explores commonly held and unexamined assumptions and misperceptions about race in science and popular culture. This collection begins with the historical origins and current uses of the concept of "race" in science. It follows with an analysis of the role of race in DNA databanks and racial disparities in the criminal justice system. Essays then consider the rise of recreational genetics in the form of for-profit testing of genetic ancestry and the introduction of racialized medicine, specifically through an FDA-approved heart drug called BiDil, marketed to African American men. Concluding sections discuss the contradictions between our scientific and cultural understandings of race and the continuing significance of race in educational and criminal justice policy.
Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Molecular Biology by David P. Clark,Nanette J. Pazdernik Pdf
Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture. NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images Fully revised art program
Africa's Gene Revolution by Matthew A. Schnurr Pdf
As development donors invest hundreds of millions of dollars into improved crops designed to alleviate poverty and hunger, Africa has emerged as the final frontier in the global debate over agricultural biotechnology. The first data-driven assessment of the ecological, social, and political factors that shape our understanding of genetic modification, Africa's Gene Revolution surveys twenty years of efforts to use genomics-based breeding to enhance yields and livelihoods for African farmers. Matthew Schnurr considers the full range of biotechnologies currently in commercial use and those in development - including hybrids, marker-assisted breeding, tissue culture, and genetic engineering. Drawing on interviews with biotechnology experts alongside research conducted with more than two hundred farmers across eastern, western, and southern Africa, Schnurr reveals a profound incongruity between the optimistic rhetoric that accompanies genetic modification technology and the realities of the smallholder farmers who are its intended beneficiaries. Through the lens of political ecology, this book demonstrates that the current emphasis on improved seeds discounts the geographic, social, ecological, and economic contexts in which the producers of these crops operate. Bringing the voices of farmers to the foreground of this polarizing debate, Africa's Gene Revolution contends that meaningful change will come from a reconfiguration not only of the plant's genome, but of the entire agricultural system.
One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.
Remarkable advances in molecular genetics have brought benefits ranging from more flavorful tomatoes to inexpensive human insulin produced in bacteria. But not everyone welcomes the inevitable "genetic revolution." Perhaps because experts and the general public belatedly recognized that the benefits of other technologies have come at great cost--pollution of the environment, exhaustion of natural resources, even damage to the atmosphere--many assume that similarly unintended and unforeseen harmful consequences are inevitable for biotechnology. What monsters and disasters, they wonder, will accompany the miracles of this latest advance? In The Genetic Revolution Bernard D. Davis and other experts address such fears with clear explanations of molecular genetics, its practical applications in biotechnology, its legal implications, and its surprising historical context. In fact, "biotechnology" is as old as civilization itself--and was originally called "domestication": the adaptation of initiallywild organisms, by empirical genetic selection, to meet human needs. And the scientific record shows that, unlike more recent technologies based on the physical sciences, the great benefits of domestication have been remarkably free of harmful side effects. Defenders argue that the new techniques of genetic engineering will simply increase the speed, precision, and range of domestication. However, the purpose will remain the same: to strengthen those traits, in animals, plants, or microbes, that make the organism more useful for humans. To ensure that all sides of the debate are heard, Davis has chosen outstanding contributors with a wide range of viewpoints--from apprehensive toenthusiastic--and a variety of backgrounds, including political science, law, and government regulation, as well as biology and medicine. With the latest information on the likely impact of genetic engineering in agriculture, animal husbandry, ecology, and medical research and practice, The Genetic Revolution introduces scientific facts and informed opinions to an emotional and often confusing public discussion.
