The Genome Of Drosophila Melanogaster

Author : Dan L. Lindsley,Georgianna G. Zimm
Publisher : Academic Press
Page : 1144 pages
File Size : 55,9 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323139847

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The Genome of Drosophila Melanogaster by Dan L. Lindsley,Georgianna G. Zimm Pdf

Dedicated to the memory of George Lefevre in recognition of his exhaustive cytogenetic analysis of the X chromosome, The Genome of Drosophila melanogaster is the complete compendium of what is known about the genes and chromosomes of this widely used model organism. The volume is an up-to-date revision of Lindsley and Grell's 1968 work, Genetic Variations of Drosophila melanogaster. The new edition contains complete descriptions of normal and mutant genes including phenotypic, cytological, molecular, and bibliographic information. In addition, it describes thousands of recorded chromosome rearrangements used in research on Drosophila. This handbook and its accompanying polytene chromosome maps, are sturdily bound into the book as foldouts and available as a separate set, are essential research tools for the Drosophila community. Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature Describes normal chromosome complement, special chromosome constructs, transposable elements, departures from diploidy, satellite sequences, and nonchromosomal inheritance Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the end of 1989 Contains the cytogenetic map of all genes as of mid-1991 Contains the original polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the detailed maps of the chromosome arms produced by C.B. and P.M. Bridges All maps are reprinted as high-quality foldouts sturdily bound into the volume Maps may also be purchased separately in an eight-map packet, for laboratory and student use

Author : Dan L. Lindsley,Georgianna G. Zimm
Publisher : Unknown
Page : 1133 pages
File Size : 42,9 Mb
Release : 1992
Category : Science
ISBN : 0124509908

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The Genome of Drosophila Melanogaster by Dan L. Lindsley,Georgianna G. Zimm Pdf

Dedicated to the memory of George Lefevre in recognition of his exhaustive cytogenetic analysis of the X chromosome, The Genome of Drosophila melanogaster is the complete compendium of what is known about the genes and chromosomes of this widely used model organism. The volume is an up-to-date revision of Lindsley and Grell's 1968 work, Genetic Variations of Drosophila melanogaster. The new edition contains complete descriptions of normal and mutant genes including phenotypic, cytological, molecular, and bibliographic information. In addition, it describes thousands of recorded chromosome rearrangements used in research on Drosophila. This handbook and its accompanying polytene chromosome maps, are sturdily bound into the book as foldouts and available as a separate set, are essential research tools for the Drosophila community. Key Features * Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature Describes normal chromosome complement, special chromosome constructs, transposable elements, departures from diploidy, satellite sequences, and nonchromosomal inheritance * Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the end of 1989 Contains the cytogenetic map of all genes as of mid-1991 * Contains the original polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the detailed maps of the chromosome arms produced by C.B. and P.M. Bridges * All maps are reprinted as high-quality foldouts sturdily bound into the volume * Maps may also be purchased separately in an eight-map packet, for laboratory and student use

Author : Dan L. Lindsley,Georgianna G. Zimm
Publisher : Unknown
Page : 1133 pages
File Size : 48,5 Mb
Release : 1992
Category : Science
ISBN : 0124509916

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The Genome of Drosophila Melanogaster by Dan L. Lindsley,Georgianna G. Zimm Pdf

Dedicated to the memory of George Lefevre in recognition of his exhaustive cytogenetic analysis of the X chromosome, The Genome of Drosophila melanogaster is the complete compendium of what is known about the genes and chromosomes of this widely used model organism. The volume is an up-to-date revision of Lindsley and Grell's 1968 work, Genetic Variations of Drosophila melanogaster. The new edition contains complete descriptions of normal and mutant genes including phenotypic, cytological, molecular, and bibliographic information. In addition, it describes thousands of recorded chromosome rearrangements used in research on Drosophila. This handbook and its accompanying polytene chromosome maps, are sturdily bound into the book as foldouts and available as a separate set, are essential research tools for the Drosophila community. Key Features * Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature * Describes normal chromosome complement, special chromosome constructs, transposable elements, departures from diploidy, satellite sequences, and nonchromosomal inheritance * Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the end of 1989 * Contains the cytogenetic map of all genes as of mid-1991 * Contains the original polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the detailed maps of the chromosome arms produced by C.B. and P.M. Bridges * All maps are reprinted as high-quality foldouts sturdily bound into the volume * Maps may also be purchased separately in an eight-map packet, for laboratory and student use

Author : Dan L. Lindsley
Publisher : Unknown
Page : 158 pages
File Size : 52,6 Mb
Release : 1986
Category : Electronic
ISBN : OCLC:174308488

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The Genome of Drosophila Melanogaster by Dan L. Lindsley Pdf

Author : Gustavo Maroni
Publisher : Oxford University Press
Page : 428 pages
File Size : 53,5 Mb
Release : 1993-06-24
Category : Science
ISBN : 9780198023524

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An Atlas of Drosophila Genes by Gustavo Maroni Pdf

Drosophila, the common fruit fly, is the most extensively studied of all organisms from the standpoint of genetics and cytology. This atlas summarizes what is known about the approximately 100 Drosophila genes for which the complete nucleotide sequence is known. Each entry includes a description of the gene's molecular organization and expression, the complete nucleotide and amino acid sequences, maps of interesting structures, highlights of functional features and promoter regulatory regions, and selected references to the primary literature. A separate section of the atlas considers different aspects of gene organization as they occur in the Drosophila genome. Topics covered include size correlations among various genetic elements, splicing signals, translation initiation signals, and codon bias. The work represents a new milestone in summarizing current information and making it easily accessible to geneticists and biologists.

Author : Pierre Capy,Patricia Gibert,Ian Boussy
Publisher : Springer Science & Business Media
Page : 292 pages
File Size : 41,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400709652

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Drosophila melanogaster, Drosophila simulans: So Similar, So Different by Pierre Capy,Patricia Gibert,Ian Boussy Pdf

This book brings together most of the information available concerning two species that diverged 2-3 million years ago. The objective was to try to understand why two sibling species so similar in several characteristics can be so different in others. To this end, it was crucial to confront all data from their ecology and biogeography with their behavior and DNA polymorphism. Drosophila melanogaster and Drosophila simulans are among the two sibling species for which a large set of data is available. In this book, ecologists, physiologists, geneticists, behaviorists share their data on the two sibling species, and several scenarios of evolution are put forward to explain their similarities and divergences. This is the first collection of essays of its kind. It is not the final point of the analyses of these two species since several areas remain obscure. However, the recent publication of the complete genome of D. melanogaster opens new fields for research. This will probably help us explain why D. melanogaster and D. simulans are sibling species but false friends.

Author : Jessika L. Regan
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 43,7 Mb
Release : 2014
Category : Drosophila melanogaster
ISBN : 1631175157

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Drosophila Melanogaster by Jessika L. Regan Pdf

Drosophila melanogaster is a species of fly in the family drosophilidae. It is generally known as the common fruit fly or vinegar fly. The use of Drosophila melanogaster in biological sciences has spanned over 100 years. Its history has a promising beginning, where D. melanogaster become one of the most popular models for studies involving modern biology. The fly is small and yellow-brown, with brick red eyes and transverse black rings across the abdomen. Although it has a relatively simple body structure, Drosophila has a number of characteristics which make it a suitable model for studying host interactions with important human pathogens. The contributors of this book discuss genes linked to species diagnostic phenotype in Drosophila; Drosophila melanogaster and how it relates to human malignancies; and Drosophila melanogaster as a host model for studying the pathogenesis and host-pathogen interaction of the Staphylococcus aureus infection.

Author : Anonim
Publisher : Academic Press
Page : 789 pages
File Size : 44,8 Mb
Release : 1995-01-25
Category : Science
ISBN : 9780080859422

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Drosophila melanogaster: Practical Uses in Cell and Molecular Biology by Anonim Pdf

Drosophila melanogaster: Practical Uses in Cell and Molecular Biology is a compendium of mostly short technical chapters designed to provide state-of-the art methods to the broad community of cell biologists, and to put molecular and cell biological studies of flies into perspective. The book makes the baroque aspects of genetic nomenclature and procedure accessible to cell biologists. It also contains a wealth of technical information for beginning or advanced Drosophila workers. Chapters, written within a year of publication, make this topical volume a valuable laboratory guide today and an excellent general reference for the future. Key Features* Collection of ready-to-use, state-of-the art methods for modern cell biological and related research using Drosophila melanogaster* Accessible to both experienced Drosophila researchers and to others who wish to join in at the cutting edge of this system * Drosophila offers an easily managed life cycle, inexpensive lifestyle, extraordinarily manipulable molecular and classical genetics, now combined with powerful new cell biology techniques * Introduction and overview sections orient the user to the Drosophila literature and lore * Six full-color plates and over 100 figures and tables enhance the understanding of these cell biology techniques

Author : Stephanie Elizabeth Mohr
Publisher : Harvard University Press
Page : 270 pages
File Size : 40,9 Mb
Release : 2018-03-09
Category : Science
ISBN : 9780674984738

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First in Fly by Stephanie Elizabeth Mohr Pdf

A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these “first in fly” findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.

Author : Christian Dahmann
Publisher : Springer Nature
Page : 423 pages
File Size : 45,5 Mb
Release : 2022-08-18
Category : Science
ISBN : 9781071625415

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Drosophila by Christian Dahmann Pdf

This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and cell lineage tracing, protein inhibition and tagging, optogenetic and optochemical control of tissue mechanics, AFM measurements, sample preparation for electron microscopy, live imaging of different tissues and organs, and quantitative image analysis. Written in the format of the highly successful Methods in Molecular Biology series, chapters include an introduction to their topic, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls Authoritative and cutting-edge, Drosophila: Methods and Protocols, Third Edition serves as a useful and practical guide to new researchers and experts using Drosophila as a model system. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author : Daryl S. Henderson
Publisher : Springer Science & Business Media
Page : 467 pages
File Size : 47,7 Mb
Release : 2008-02-03
Category : Science
ISBN : 9781592596652

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Drosophila Cytogenetics Protocols by Daryl S. Henderson Pdf

Leading drosophilists describe in step-by-step detail all the essential techniques for studying Drosophila chromosomes and suggest new avenues for scientific exploration. The chapters emphasize specimen preparation (from dissection to mounting) and cover both polytene and mitotic/meiotic chromosomes in depth. Each fully tested and readily reproducible protocol offers a background introduction, equipment and reagent lists, and tips on troubleshooting and avoiding pitfalls. A cutting-edge FISH and immunolocalization technique will be important for discovering how DNA sequence influences higher-order chromosome architecture and ultimately gene expression.

Author : Farzana Khan Perveen
Publisher : BoD – Books on Demand
Page : 270 pages
File Size : 45,5 Mb
Release : 2018-02-28
Category : Technology & Engineering
ISBN : 9789535138532

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Drosophila melanogaster by Farzana Khan Perveen Pdf

This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.

Author : M. Ashburner
Publisher : CSHL Press
Page : 128 pages
File Size : 47,7 Mb
Release : 2006
Category : Science
ISBN : 9780879698027

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Won for All by M. Ashburner Pdf

This is the story of the sequencing of the fly genome as told by one of the participants, Michael Ashburner. Written in a diary-like form, half the story is told in numerous footnotes. Ashburner has written a delightful, candid, irreverent, on-the-scene tale filled with eccentric personalities all focused on a single goal. The book also contains an Epilogue that puts Drosophilaas a model system in historical context, and an Afterword that discusses the impact the genome sequence has had on the study of Drosophila.Also included are portraits by Lewis Miller of some of the principal characters. About the author:Michael Ashburner is Professor of Biology in the Department of Genetics at the University of Cambridge. By training and inclination, he is a Drosophilageneticist, although for more than a decade, he has not been where he belongs – the lab bench – but in front of computer screens. He spent six years at the European Bioinformatics Institute, first as the Institute's Research Programme Coordinator, and then as its Joint-Head. He is a Fellow of the Royal Society and an Honorary Foreign Member of the American Academy of Arts and Sciences.

Author : Ulrich Graf,Nancy van Schaik,Friedrich E. Würgler
Publisher : Springer
Page : 262 pages
File Size : 50,9 Mb
Release : 1992-03-16
Category : Science
ISBN : UOM:39015053939651

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Drosophila Genetics by Ulrich Graf,Nancy van Schaik,Friedrich E. Würgler Pdf

The Biological Sciences are in the midst of a scientific rev olution. During the past decade under the rubric of molecu lar biology, chemistry and physics have assumed an integral role in biological research. This is especially true in ge netics, where the cloning of genes and the manipulation of genomic DNA have become in many organisms routine laboratory procedures. These noteworthy advances, it must be empha sized, especially in molecular genetics, are not autonomous. Rather, they have been accomplished with those organisms whose formal genetics has been documented in great detail. For the beginning student or the established investigator who is interested in pursuing eukaryote molecular genetic re search, Drosophila melanogaster, with its rich body of formal genetic information is one organism of choice. The book "Drosophila Genetics. A Practical Course" is an indispens able source of information for the beginner in the biology and formal genetics of Drosophila melanogaster. The scope of this guide, a revision and enlargement of the original German language version, is broad and instructive. The information included ranges from the simple, but necessary, details on how to culture and manipulate Drosophila flies to a series of more sophisticated genetic experiments. After completing the experiments detailed in the text, all students - neophyte or experienced - will be richly rewarded by having acquired a broad base of classical genetics information relevant for the biologist in its own right and prerequisite to Drosophila genetics research - formal and/or molecular. Davis, California, Melvin M.

Author : Seppo Lakovaara
Publisher : Springer Science & Business Media
Page : 466 pages
File Size : 51,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461583219

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Advances in Genetics, Development, and Evolution of Drosophila by Seppo Lakovaara Pdf

In 1906 Castle, Carpenter, Clarke, Mast, and Barrows published a paper entitled "The effects of inbreeding, cross-breeding, and selection upon the fertility and variability of Drosophila." This article, 55 pages long and published in the Proceedings of the Amer ican Academy, described experiments performed with Drosophila ampe lophila Lov, "a small dipterous insect known under various popular names such as the little fruit fly, pomace fly, vinegar fly, wine fly, and pickled fruit fly." This study, which was begun in 1901 and published in 1906, was the first published experimental study using Drosophila, subsequently known as Drosophila melanogaster Meigen. Of course, Drosophila was known before the experiments of Cas tles's group. The small flies swarming around grapes and wine pots have surely been known as long as wine has been produced. The honor of what was the first known misclassification of the fruit flies goes to Fabricius who named them Musca funebris in 1787. It was the Swedish dipterist, C.F. Fallen, who in 1823 changed the name of ~ funebris to Drosophila funebris which was heralding the beginning of the genus Drosophila. Present-day Drosophila research was started just 80 years ago and first published only 75 years ago. Even though the history of Drosophila research is short, the impact and volume of study on Drosophila has been tremendous during the last decades.