The Laboratory Rat Second Edition

Author : Mark A. Suckow,Steven H. Weisbroth,Craig L. Franklin
Publisher : Elsevier
Page : 928 pages
File Size : 41,7 Mb
Release : 2005-12-20
Category : Science
ISBN : 9780080454320

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The Laboratory Rat by Mark A. Suckow,Steven H. Weisbroth,Craig L. Franklin Pdf

The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. At least 50% new information than first edition Includes topics on rat genetics and genomics, occupational health, and experimental models The premier source of information on the laboratory rat

Author : Patrick Sharp,Jason S. Villano
Publisher : CRC Press
Page : 403 pages
File Size : 50,9 Mb
Release : 2012-12-11
Category : Medical
ISBN : 9781439829868

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The Laboratory Rat, Second Edition by Patrick Sharp,Jason S. Villano Pdf

Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.

Author : Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley
Publisher : Academic Press
Page : 1182 pages
File Size : 53,7 Mb
Release : 2019-11-10
Category : Science
ISBN : 9780128143391

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The Laboratory Rat by Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley Pdf

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research. New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included. All chapters were written by scientific and veterinary experts. This book condenses information from many sources on topics related to the care and use of rats in research. It is the premier source of information on the laboratory rat.

Author : George J. Krinke
Publisher : Elsevier
Page : 756 pages
File Size : 51,8 Mb
Release : 2000-06-20
Category : Medical
ISBN : 0080533469

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The Laboratory Rat by George J. Krinke Pdf

This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species. Each title in the series is devoted to a particular species, and draws together all available data in a "one-stop", easily accessible source. Each has similar format, with sections on the strains available, their husbandry, and special diets. Also included are sections on gross anatomy, endocrinology, and reproduction, followed by more detailed sections on neuroanatomy, vasculature, cell biology, and histology of particular organs and structures, and a section on molecular biology. High quality illustrations are included throughout and a color plate section is provided. A glossary, list of equipment suppliers, and "Quick Reference Section" are added features. The "Quick Reference Section" brings together all tables from the text, allowing readers to find data swiftly. The first volume in The Handbook of Experimental Animals Series, The Laboratory Rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. The Laboratory Rat has been divided into eight sections dealing with: * Strains and their selection for research * Housing and maintenance * Pathogens and diseases * Breeding and reproduction * Anatomy * Physiology * Procedures, including experimental surgery * Emerging techniques, including genetic engineering and molecular technology Key Features * Provides a valuable, comprehensive reference source for anybody working with the laboratory rat * Formatted in a two-color, user-friendly layout * Includes high-quality illustrations throughout as well as a color plate section * Glossary * Tables in the text are also arranged into one Quick Reference Section for ease of access to the data * Appendix of equipment suppliers

Author : Henry J. Baker,James Russell Lindsey,Steven H. Weisbroth
Publisher : Unknown
Page : 464 pages
File Size : 46,8 Mb
Release : 1979
Category : Laboratory animals
ISBN : 0120749017

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The Laboratory Rat by Henry J. Baker,James Russell Lindsey,Steven H. Weisbroth Pdf

Author : Patrick E. Sharp,Marie C. LaRegina
Publisher : CRC-Press
Page : 214 pages
File Size : 41,7 Mb
Release : 1998-08-01
Category : Medical
ISBN : 084932565X

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The Laboratory Rat by Patrick E. Sharp,Marie C. LaRegina Pdf

Laboratory animals, play an important role in biomedical research and advances. The humane care and management of these animals is an ongoing concern. This guide was created especially for individuals performing research with rats whose duties include animal facility management, animal husbandry, regulatory compliance, and technical procedures involved with their research. Basic information and common procedures are presented in detail.

Author : Robert L. Maynard,Noel Downes
Publisher : Academic Press
Page : 378 pages
File Size : 43,5 Mb
Release : 2019-02-08
Category : Medical
ISBN : 9780128118719

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Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research by Robert L. Maynard,Noel Downes Pdf

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource. Illustrated with over 100 black and white and color images to assist understanding Contains detailed descriptions and explanations to accompany all images, thus helping with self-study Designed for toxicologic research for people from diverse backgrounds, including biochemistry, pharmacology, physiology, immunology and general biomedical sciences

Author : Hans Hedrich
Publisher : Academic Press
Page : 868 pages
File Size : 55,6 Mb
Release : 2012-06-14
Category : Science
ISBN : 9780123820099

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The Laboratory Mouse by Hans Hedrich Pdf

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

Author : James G. Fox,Bennett J. Cohen,Franklin M. Loew
Publisher : Academic Press
Page : 766 pages
File Size : 53,7 Mb
Release : 2013-10-02
Category : Technology & Engineering
ISBN : 9781483269160

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Laboratory Animal Medicine by James G. Fox,Bennett J. Cohen,Franklin M. Loew Pdf

Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Author : Peggy J. Danneman,Mark A. Suckow,Cory Brayton
Publisher : CRC Press
Page : 259 pages
File Size : 49,9 Mb
Release : 2012-09-25
Category : Medical
ISBN : 9781439854211

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The Laboratory Mouse, Second Edition by Peggy J. Danneman,Mark A. Suckow,Cory Brayton Pdf

Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse.

Author : National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition
Publisher : National Academies Press
Page : 188 pages
File Size : 50,6 Mb
Release : 1995-02-01
Category : Science
ISBN : 9780309051262

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Nutrient Requirements of Laboratory Animals, by National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition Pdf

In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Author : Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley
Publisher : Academic Press
Page : 748 pages
File Size : 49,9 Mb
Release : 2017-12-18
Category : Medical
ISBN : 9780123914897

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Boorman's Pathology of the Rat by Andrew W. Suttie,Joel R. Leininger,Alys E. Bradley Pdf

Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. Contains full, four color photographs from the NTP archive and database and coverage of all rat strains Provides an organ-by-organ and system-by-system approach that presents standard diagnostic criteria and basic content on histology and histological changes Includes comprehensive and detailed background incidence data Presents detailed descriptive content regarding changes in rat models during research

Author : John J. Bogdanske,Scott Hubbard-Van Stelle,Beth M. Schiffman,Margaret Rankin Riley
Publisher : CRC Press
Page : 92 pages
File Size : 49,9 Mb
Release : 2018-08-06
Category : Electronic
ISBN : 1138453897

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Laboratory Rat Procedural Techniques by John J. Bogdanske,Scott Hubbard-Van Stelle,Beth M. Schiffman,Margaret Rankin Riley Pdf

This combination manual and downloadable resources provide much-needed training on the proper handling of rats used in biomedical research. The downloadable resources include narrated video clips that demonstrate and describe each procedural technique. The manual contains handouts with color illustrations and descriptive text for each technique, including the purpose and application of the procedure, recommended skills, and necessary supplies. It can be used as a training resource and refresher for lab animal veterinarians, veterinary technicians, animal care staff, trainers, and research investigators and staff who work with rats.

Author : Ian Q. Whishaw,Bryan Kolb
Publisher : Oxford University Press
Page : 522 pages
File Size : 44,7 Mb
Release : 2004-09-02
Category : Medical
ISBN : 9780198036845

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The Behavior of the Laboratory Rat by Ian Q. Whishaw,Bryan Kolb Pdf

Both seasoned and beginning investigators will be amazed at the range and complexity of rat behavior as described in the 43 chapters of this volume. The behavioral descriptions are closely tied to the laboratory methods from which they were derived, thus allowing the investigator to exploit both the behavior and the methods for their own research. It will also serve as an indispensable reference for other neuroscientists, psychologist, pharmacologists, geneticists, molecular biologists, zoologists, and their students and trainees.

Author : F. Claire Hankenson
Publisher : CRC Press
Page : 271 pages
File Size : 44,7 Mb
Release : 2013-10-03
Category : Medical
ISBN : 9781420004083

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Critical Care Management for Laboratory Mice and Rats by F. Claire Hankenson Pdf

For critical care of laboratory rodents, there is a scarcity of sources for comprehensive, feasible, and response-oriented information on clinical interventions specific to spontaneous and induced models of disease. With the more complex cases that need critical care management, many treatment approaches to veterinary emergencies cannot be applied directly to the laboratory rodent. The first text of its kind devoted to the challenges of critical care management for laboratory rodents, Critical Care Management for Laboratory Mice and Rats provides a specialized resource for all veterinary, husbandry, technical, and research professionals who utilize rodent models for biomedical research. The book covers the varied approaches to laboratory rodent patient care, health assessments, characteristics of specific disease models, monitoring and scoring of disease parameters, and humane interventions. Giving primary consideration to preservation of animal health and welfare, the text also considers how best to balance welfare with the achievement of proposed scientific objectives. Organized into five chapters, this full-color book covers the following topics: General Approaches for Critical Care Critical Care Management for Laboratory Mice Critical Care Management for Laboratory Rats Special Considerations for Critical Care Management in Laboratory Rodents Resources and Additional Information The author provides treatment guidelines with the expectation that they will be applied with apt professional judgment, allowing for further modification of clinical recommendations for improved patient-based care and welfare for research animals.