The Leishmaniases Old Neglected Tropical Diseases

Author : Fabrizio Bruschi,Luigi Gradoni
Publisher : Springer
Page : 245 pages
File Size : 44,5 Mb
Release : 2018-01-12
Category : Medical
ISBN : 9783319723860

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The Leishmaniases: Old Neglected Tropical Diseases by Fabrizio Bruschi,Luigi Gradoni Pdf

Out of the 20 neglected tropical diseases (NTDs) prioritized by the World Health Organization, the leishmaniases rank in the top 3 among those caused by protozoa. The purpose of this book is to provide the reader with a comprehensive and updated overview of all the aspects of leishmaniasis with a worldwide perspective – authors of many chapters include eminent scientists from both the Old and New Worlds. The chapters cover a wide range of topics, classically organized into biology and epidemiology, followed by clinical and control aspects. Following an introductory chapter intended to take the reader into the leishmaniasis complexity, a chapter on Leishmania taxonomy reports on the most recent advances in molecular and phylogenetic data. Parasite biology is then described in detail by means of two separate chapters devoted to phlebotomine vectors and reservoir hosts, respectively. The medical part of the book begins with a chapter on basic immunology and immunopathology associated with Leishmania infection, followed by a classical chapter on clinical aspects of different disease entities. The complexity of disease case management is presented by means of 3 chapters, respectively on diagnosis, treatment of visceral forms and treatment of tegumentary forms. Finally, the last chapter deals with the available approaches to control leishmaniasis and related public health issues.

Author : John O. Gyapong
Publisher : Springer Nature
Page : 561 pages
File Size : 44,8 Mb
Release : 2024-07-01
Category : Electronic
ISBN : 9783031539015

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Neglected Tropical Diseases - Sub-Saharan Africa by John O. Gyapong Pdf

Author : World Health Organization
Publisher : World Health Organization
Page : 211 pages
File Size : 54,7 Mb
Release : 2015-08-05
Category : Medical
ISBN : 9789241564861

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Investing to Overcome the Global Impact of Neglected Tropical Diseases by World Health Organization Pdf

"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Author : Peter J. Hotez
Publisher : John Wiley & Sons
Page : 275 pages
File Size : 55,6 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781555818753

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Forgotten People, Forgotten Diseases by Peter J. Hotez Pdf

Forgotten People, Forgotten Diseases Second Edition The neglected tropical diseases (NTDs) are the most common infections of the world's poor, but few people know about these diseases and why they are so important. This second edition of Forgotten People, Forgotten Diseases provides an overview of the NTDs and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. Author Peter J. Hotez highlights a new opportunity to control and perhaps eliminate these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships to create a successful environment for mass drug administration and product development activities. Forgotten People, Forgotten Diseases also Addresses the myriad changes that have occurred in the field since the previous edition. Describes how NTDs have affected impoverished populations for centuries, changing world history. Considers the future impact of alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases is an essential resource for anyone seeking a roadmap to coordinate global advocacy and mobilization of resources to combat NTDs.

Author : Farhat Afrin,Hassan Hemeg
Publisher : BoD – Books on Demand
Page : 234 pages
File Size : 42,6 Mb
Release : 2018-10-10
Category : Medical
ISBN : 9781789841015

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Leishmaniases as Re-emerging Diseases by Farhat Afrin,Hassan Hemeg Pdf

Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.

Author : John Gyapong,Boakye Boatin
Publisher : Springer
Page : 414 pages
File Size : 44,6 Mb
Release : 2016-01-13
Category : Medical
ISBN : 9783319254715

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Neglected Tropical Diseases - Sub-Saharan Africa by John Gyapong,Boakye Boatin Pdf

This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.

Author : Awanish Kumar
Publisher : Springer Science & Business Media
Page : 90 pages
File Size : 41,8 Mb
Release : 2013-09-13
Category : Medical
ISBN : 9781461488699

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Leishmania and Leishmaniasis by Awanish Kumar Pdf

​Leishmania-related illnesses remain among the world’s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis. Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.​

Author : Anonim
Publisher : ScholarlyEditions
Page : 66 pages
File Size : 48,7 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481610575

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Leishmaniasis—Advances in Research and Treatment: 2012 Edition by Anonim Pdf

Leishmaniasis—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Leishmaniasis in a concise format. The editors have built Leishmaniasis—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Leishmaniasis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Leishmaniasis—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Fernando Almeida-Souza,Kátia Da Silva Calabrese,Ana Lucia Abreu-Silva,Flávia Cardoso
Publisher : BoD – Books on Demand
Page : 168 pages
File Size : 50,7 Mb
Release : 2024-04-24
Category : Medical
ISBN : 9781837683109

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Leishmania Parasites by Fernando Almeida-Souza,Kátia Da Silva Calabrese,Ana Lucia Abreu-Silva,Flávia Cardoso Pdf

Leishmania parasites are a group of pathogens responsible for diseases known as leishmaniases. These pathologies affect predominantly the poorest people, mainly in tropical countries, exerting a high impact on mortality and morbidity rates. The absence of a vaccine and the reduced drug arsenal, associated with the diversity in the clinical presentation and hosts, highlight the complexity of the disease and its position as a worldwide public health problem. This book addresses different aspects related to leishmaniases, such as epidemiology, immunopathology, and the challenges of disease in humans and domestic animals. The information presented contributes to a better understanding of the Leishmania parasites and different clinical forms produced by infection, as well as their distribution around the world and their impacts on public health.

Author : Claire J Standley,Jennifer K Peterson,Jared S Bakuza
Publisher : Mdpi AG
Page : 160 pages
File Size : 49,9 Mb
Release : 2021-08-18
Category : Health & Fitness
ISBN : 3036502866

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One Health and Neglected Tropical Diseases by Claire J Standley,Jennifer K Peterson,Jared S Bakuza Pdf

"One Health" is defined as an approach to achieve better health outcomes for humans, animals, and the environment through collaborative and interdisciplinary efforts. The One Health framework is increasingly being applied to the management, control, and even elimination of neglected tropical diseases (NTDs), a set of infectious diseases that, collectively, affect more than one billion people across almost 150 countries. NTDs are some of the most common infections in the world; they cause substantial morbidity and mortality, particularly in regions with little access to medical care and other resources. Although there is increasing recognition of the major public health threat presented by NTDs, the ecological complexities of their transmission continue to pose challenges for their control and elimination. Some NTDs are zoonotic, meaning that they can be transmitted between humans and animals and, as such, present obstacles for public health and veterinary services in addition to concerns for wildlife conservation. Vector-borne NTDs necessitate measures that integrate consideration of the environment into public health strategies in order to sustainably reduce disease transmission. This book presents a collection of papers that explore various aspects of how the One Health concept is being applied to NTD control around the world, from genomics and diagnostic tools to improved surveillance and disease management. Encompassing research from Central America, the Caribbean, Asia, and sub-Saharan Africa, the collection emphasizes the diversity of NTDs as well as the critical importance of multisectoral collaboration for their control and elimination.

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 48,6 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

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Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Author : Roberto Arenas
Publisher : CRC Press
Page : 358 pages
File Size : 46,5 Mb
Release : 2001-01-01
Category : Science
ISBN : 9781498712750

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Tropical Dermatology by Roberto Arenas Pdf

Tropical diseases are not merely a group of nosologic diseases indigenous to the intertropical zone. Many are diseases of poor public health originating from poverty, ignorance, and population upheaval. Tropical dermatoses represent a public health problem in 127 countries with a population of 3 billion people who do not have access to health care.

Author : World Health Organization. Department of Control of Neglected Tropical Diseases,World Health Organization
Publisher : World Health Organization
Page : 184 pages
File Size : 49,8 Mb
Release : 2010
Category : Medical
ISBN : 9789241564090

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Working to Overcome the Global Impact of Neglected Tropical Diseases by World Health Organization. Department of Control of Neglected Tropical Diseases,World Health Organization Pdf

"Neglected tropical diseases (NTDs) blight the lives of a billion people worldwide and threaten the health of millions more. These ancient companions of poverty weaken impoverished populations, frustrate the achievement of health in the Millennium Development Goals and impede global health and economies has convinced governments, donors, the pharmaceutical industry and other agencies, including nongovernmental organizations (NGOs), to invest in preventing and controlling this diverse group of diseases. Global efforts to control "hidden" diseases, such as dracunculiasis (guinea-worm disease), leprosy, gains including the imminent eradication of dracunculiasis. Since 1989 (when most endemic countries began reporting monthly from each endemic village), the number of new dracunculiasis cases has fallen from 892 055 in 12 endemic countries to 3190 in 4 countries in 2009, a decrease of more than 99%. The World Health Organization (WHO) recommends five public-health strategies for the prevention and control of NTDs: preventive chemotherapy; intensified case-management; vector control; the provision of safe water, sanitation and hygiene; and veterinary public health (that is, applying veterinary sciences to ensure the health and well-being of humans). Although one approach and delivered locally." - p. vii

Author : Fernando Cobo
Publisher : Elsevier
Page : 240 pages
File Size : 50,6 Mb
Release : 2014-10-07
Category : Medical
ISBN : 9781908818737

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Imported Infectious Diseases by Fernando Cobo Pdf

The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.

Author : Gilberto Antonio Bastidas Pacheco,Asghar Ali Kamboh
Publisher : BoD – Books on Demand
Page : 376 pages
File Size : 49,5 Mb
Release : 2020-06-17
Category : Medical
ISBN : 9781789859010

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Parasitology and Microbiology Research by Gilberto Antonio Bastidas Pacheco,Asghar Ali Kamboh Pdf

The study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.