Download Full eBooks in PDF
The Mathematical Modeling Of Metabolic And Endocrine Systems Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of The Mathematical Modeling Of Metabolic And Endocrine Systems book. This book definitely worth reading, it is an incredibly well-written.
Author : Ewart R. Carson
Publisher : Unknown
Page : 418 pages
File Size : 45,7 Mb
Release : 2024-06-07
Category : Electronic
ISBN : 0783728344
Author : Ewart R. Carson,Claudio Cobelli,Ludwik Finkelstein
Publisher : Unknown
Page : 426 pages
File Size : 45,6 Mb
Release : 1983-02-25
Category : Medical
ISBN : UCAL:B4513806
Introduces the concepts, methods and techniques of model formulation, identification, and validation as applicable to metabolic and endocrine processes. Shows how modeling can be used to provide a concise description of complex dynamic processes, to test hypotheses concerning physiological and biochemical structure, and to estimate physiological quantities (parameters) that otherwise would not be directly accessible to measurement. Includes numerous examples and case studies.
Author : Darko Stefanovski,Giovanni Pacini,Ray Boston
Publisher : Frontiers Media SA
Page : 98 pages
File Size : 41,7 Mb
Release : 2022-01-04
Category : Medical
ISBN : 9782889719426
Author : Simon Goede,Melvin Khee-Shing Leow
Publisher : River Publishers
Page : 338 pages
File Size : 51,6 Mb
Release : 2018-02-22
Category : Technology & Engineering
ISBN : 9788793609594
In recent years, a considerable amount of effort has been devoted, both in industry and academia, towards the behavioral modeling, evaluation and prediction of the hypothalamus pituitary thyroid system. Thyroid Systems Engineering targets an optimal treatment of people suffering from thyroid hormone disorders. The content is motivated by in-depth observations of such patients whose rich data supported the theoretical framework arising from formal mathematical reasoning, guided by the nature of thyroid physiology. Leveraging on the insights emerging from the unique combination of an electrical engineer working with a clinical thyroidologist, and both being scientists skilled in mathematics, the authors introduce this new discipline and field of scientific investigation aptly designated as Thyroid Systems Engineering. Readers will discover that mathematics can indeed model the behavior of the hypothalamus-pituitary-thyroid (HPT) axis. Focused on modeling, each of the eighteen chapters gives the reader a notion of the application of relevant mathematics to pertinent issues encountered in mainstream thyroidology. Many cellular processes resemble the flux of variables and states in a complex multi-parameter space through time analogous to current flow in electrical networks. It is then logical to apply the principles and physical laws of electrodynamics, electrical network theory, control systems theory and signal theory to many of the biological phenomena encountered in endocrinology. Such an approach is used liberally throughout the book and successfully yields elegant solutions to a number of models presented within. This book can serve as a reference to mathematical modeling in other aspects of endocrine physiology, and as the starting point for a fundamental course in medical modeling. It will appeal to postgraduates in electrical engineering, academic physicians and biomedical researchers. Further, readers equipped with advanced calculus, electrical network theory, control theory and signal theory should be able to follow the mathematical expositions that describe thyrotropic control. They represent a new discipline based on mathematical modeling in physiology applicable to medical diagnostics, measurement and treatment to cooperate in the clinical team and realize an optimized treatment for patients.
Author : Janet A. Novotny,Michael H. Green,Ray C. Boston
Publisher : Springer Science & Business Media
Page : 470 pages
File Size : 47,6 Mb
Release : 2003-10-31
Category : Computers
ISBN : 0306478811
This volume is the proceedings of the 7th Mathematical Modeling in Experimental Nutrition Conference held at Penn State University July 29 until August 1, 2000. The book addresses the determination of optimal intakes of nutrients and food components to provide lifelong health and reduce incidence of disease. Mathematical modelling provides a means of rigorously defining the functions of a system and using a variety of conditions to stimulate responses. This volume presents the newest advances in modelling and related experimental techniques required to meet the new challenges currently facing nutrition and biological science.
Author : Ewart R. Carson,Claudio Cobelli,Ludwik Finkelstein
Publisher : Unknown
Page : 424 pages
File Size : 54,7 Mb
Release : 1983-02-25
Category : Medical
ISBN : UOM:39015004484484
Introduces the concepts, methods and techniques of model formulation, identification, and validation as applicable to metabolic and endocrine processes. Shows how modeling can be used to provide a concise description of complex dynamic processes, to test hypotheses concerning physiological and biochemical structure, and to estimate physiological quantities (parameters) that otherwise would not be directly accessible to measurement. Includes numerous examples and case studies.
Author : Alexander Medvedev,Alexander Churilov,Zhanybai T. Zhusubaliyev, PhD
Publisher : Academic Press
Page : 0 pages
File Size : 42,9 Mb
Release : 2020-12-15
Category : Technology & Engineering
ISBN : 0128130539
Impulsive Mathematical Models of Endocrine Regulation demonstrates recently-developed mathematical models portraying pulse-modulated regulation in endocrine systems, taking a pragmatic engineering stance by starting with the necessary theoretical background on analytical tools, progressing through a number of mathematical models of increasing complexity, and illustrating the feasibility and fidelity of the mathematical constructs on actual biological data. Compared to a commonplace, theory-oriented book on dynamical systems and control which typically presents a group of design or analysis techniques, the book originates from a real-life problem of fundamental value and introduces mathematical tools that have specifically been devised to solve it. Presents results on impulsive mathematical models of endocrine regulation in a systematic, comprehensive and accessible manner Introduces researchers and engineers specializing in dynamical systems to a rapidly-growing topic Provides biomedical engineering and biological researchers with mathematical modeling and analysis tools for continuous systems using episodic feedback exemplified by non-basal endocrine regulation
Author : Andrew J. Clifford,Hans-Georg Müller
Publisher : Springer Science & Business Media
Page : 413 pages
File Size : 47,8 Mb
Release : 2013-11-21
Category : Science
ISBN : 9781489919595
Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.
Author : Anonim
Publisher : Academic Press
Page : 362 pages
File Size : 42,7 Mb
Release : 1996-12-02
Category : Technology & Engineering
ISBN : 0080567851
This book developed from a series of conferences to facilitate the application of mathematical modeling to experimental nutrition. As nutrition science moves from prevention of gross deficiencies to identifying requirements for optimum long term health, more sophisticated methods of nutritional assessment will be needed. Collection and evaluation of kinetic data may be one such method. This books opens with chapters giving specific examples of the application of modeling techniques to vitamin A, carotenoids, folate, vitamin b-6, glycogen phosphorylase, transthyretin, amino acids, and energy metabolism. Obtaining kinetic data on internal processes is a major challenge; therefore, the text includes chapters on the use of microdialysis and ultrafiltration, use of membrane vesicles, and culture of mammary tissue. Many of the authors use the Simulation, Analysis and Modeling program which allows compartmental models to be described without specifying the required differential equations. The final sections of the book, however, present some more mathematical descriptions of physiological processes, including bioperiodicity, metabolic control, and membrane transport; discussions of some computational aspects of modeling such as parameter distributions, linear integrators and identifiability; and alternative mathematical approaches such as neural networks and graph theory. Specific, detailed examples of applications of modeling to vitamins, proteins, amino acids, and energy metabolism Novel methods for collecting kinetic data--microdialysis, ultrafiltration, membrane vesicles, and the culture of mammary tissue Mathematical treatment of complex metabolic processes including bioperiodicity, metabolic control, and membrane transport Computational approaches to distribution of kinetic parameters, evaluation of linear integrators, and identifiability Alternative mathematical approaches--neural networks and graph theory Detailed descriptions of the application of modeling to a variety of nutrients
Author : Vincenzo Capasso,Enea Grosso,Stefano L. Paveri-Fontana
Publisher : Springer Science & Business Media
Page : 543 pages
File Size : 52,7 Mb
Release : 2013-03-13
Category : Mathematics
ISBN : 9783642932878
Author : R.L. Baldwin
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 40,7 Mb
Release : 1995-05-31
Category : Medical
ISBN : 041259160X
Role of mminants in human food production; Whyan animal scientist would choose to model animal systems; Basic organization of this book; Modeling principIes and terminology; Classification of models; Objectives in modeling; The modeling process I objective statements, block diagrams, equation forms and parameterization; Steps in modeling; Setting the modeling objective; Block diagrams; Formulation of mathematical statements; Development of numerical inputs; The modeling process II - solution algorithms, model evaluations and parameter estimation; Model solution algorithms; Evaluation of management and research models; Evaluation and use of analytical models for parameter estimation; Decision support software; Animal energetic models; Thermodynamic concepts in nutrition; Historical development of bases for feeding system models; Energy requirements for maintenance and production; Equations used to estimate maintenance and costs of production; Components of maintenanace; Protein and amino acid models; Current protein and amino acid systems; Analytic models of amino aicd and protein metabolism; Dynamic modeling; Biology and algebraic models of ruminant digestion; The rumen microbes and their metabolism; Balance models of ruminant digestion; An analytical model of rumen digestion; Microbial growth elements; Biology and algebraic models of growth; Classical equations for growth; Nutritional models of growth; Concepts of lhe basic biology of growth used in mechanistic models; Biology of lactation; Decent evolution of feeding systems for lactating dairy cattle; An analytical model of nutrient transactions during lactation; Dynamic models of ruminant digestion; Early dynamic models; Current dynamic models; Dynamic models of ruminant adipose tissue metabolism; Evolution of steady-state balance model; Radioisotope tracer elemets; Dynamic models of ruminant mammary metabolism; Development of model inputs and initial parameters; Descriptions of a model of mammary gland metabolism; Dynamic models of liver and viscera metabolism; Overall structure and notation; Mechanistic, dynamic models of growth; Beef growth models; Sheep growth and metabolism model; Lactation Background on MOLL Y. CSL; The program MOLL Y. CSL; Evaluation and use of a growth and lactation model; Behavioral analyses; Sensitivity analyses; Bioeconomic analyse.
Author : Giulian Mariant
Publisher : Springer Science & Business Media
Page : 409 pages
File Size : 40,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461327936
This book represents a factual account of the proceedings of an international symposium on the pathophysiology of plasma protein metabolism, which was organised in October 1982 by the Plasmaprotein and Immunology Division of the C.N.R. Institute of Clinical Physiology at the University of Pisa (Italy). Several of the contributors are former members of the International Study Group on Plasma Protein Metabolism, the last meeting of which was held in Turin (Italy) in 1974, under the auspices of the scientific organisation of the same institute. The symposium took the form of a series of lectures, with the main objective of providing a positive contribution to the state of the art of several topics related to the kinetic and pathophysiological factors regulating the synthesis, distribution and degradation of plasma proteins. The first four chapters form a group, each one considering a special aspect of the kinetics of turnover and distribution of plasma proteins in general; particular attention is paid to the recent advances in the field of kinetic modelling, the choice of the best models and the optimisation of the experimental designs. The next seven chapters consider the regulation of synthesis, distribution and catab olism of various classes of plasma proteins including albumin, immunoglobulins, complement fractions and acute-phase proteins. The remaining chapters deal with metabolic studies of various plasma proteins (including tumour markers, coagUlation proteins and lipoproteins) in different disease states, such as malig nancies, coagulative disorders, malnutrition and the extensive group of athero sclerotic cardiovascular diseases.
Author : Murray S. Klamkin
Publisher : SIAM
Page : 346 pages
File Size : 41,8 Mb
Release : 1987-01-01
Category : Technology & Engineering
ISBN : 9780898712049
Mathematics of Computing -- Miscellaneous.
Author : Robert B. Northrop
Publisher : CRC Press
Page : 469 pages
File Size : 41,8 Mb
Release : 2020-11-25
Category : Medical
ISBN : 9781000108651
From a biomedical engineering perspective, this book takes an analytic, quantitative approach to describing the basic components of physiological regulators and control systems (PRCs). In Endogenous and Exogenous Regulation and Control of Physiological Systems, the author provides grounding in the classical methods of designing linear and nonlinear systems. He also offers state-of-the-art material on the potential of PRCs to treat immune system ailments, most notably AIDS and cancer. The book focuses on certain "wet" physiological regulators, such as those using endocrine hormones as parametric control substances. Endogenous and Exogenous Regulation and Control of Physiological Systems includes simulations that illustrate model validations and the putative control of cancer and HIV proliferation. It explores novel, untried immunotherapies on the cutting-edge of PRC treatment and explores the latest technologies.
Author : Richard M. Cowett
Publisher : Springer Science & Business Media
Page : 1264 pages
File Size : 43,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461216421
Here, a stellar international group of contributors examines the various aspects of metabolism in the human adult during pregnancy, in the foetus, and in the new-born. This second edition has been completely updated and now has more than 17 new chapters. Divided into five sections, the book contains discussions of methodologies using molecular biology techniques, expanded coverage of central nervous system metabolism, and an entirely new section on organ-specific metabolism organised according to each organ-system. A must for every physician who cares for the pregnant patient and her child.