The Mosaic Of Autoimmunity

Author : Carlo Perricone,Yehuda Shoenfeld
Publisher : Academic Press
Page : 728 pages
File Size : 43,7 Mb
Release : 2019-02-15
Category : Medical
ISBN : 9780128143070

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Mosaic of Autoimmunity by Carlo Perricone,Yehuda Shoenfeld Pdf

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis. Highlights the concept of the mosaic of autoimmune manifestations Includes new visions on unsuspected molecules Provides updated knowledge to physicians helping patients with autoimmune diseases Presents thorough, up-to-date information on specific diseases, along with clinical applications

Author : Yehuda Shoenfeld,David Isenberg
Publisher : Elsevier Science Limited
Page : 523 pages
File Size : 55,8 Mb
Release : 1989
Category : Medical
ISBN : 0444811842

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The Mosaic of Autoimmunity by Yehuda Shoenfeld,David Isenberg Pdf

This book comprehensively sets out the common aetiopathogenetic mechanisms shared by many, apparently diverse, diseases of the immune system. Unlike most other texts it does not emphasise the differences between autoimmune diseases, but establishes their many common links including hormonal effects, dietary and immunogenetic influences, complement deficiencies and environmental factors. Special attention is given to the effects of ageing and the relationship with malignancies. The scope of the book is very broad so as to cover the integration of the many diverse components which interact to cause autoimmunity, and it contains many 1988 and 1989 references and over 100 figures and tables, offering an attractive, up-to-date guide to modern concepts. It will greatly assist immunologists wishing to enter the field of autoimmunity, and will serve as an invaluable reference work for those already working in it.

Author : R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld
Publisher : Elsevier
Page : 540 pages
File Size : 54,9 Mb
Release : 1997-11-19
Category : Medical
ISBN : 0080534430

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Idiotypes in Medicine: Autoimmunity, Infection and Cancer by R.C. Kennedy,S. Ferrone,Yehuda Shoenfeld Pdf

This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Author : Yehuda Shoenfeld,David Isenberg
Publisher : Unknown
Page : 523 pages
File Size : 40,5 Mb
Release : 1989
Category : Maladies auto-immunes
ISBN : 0444801626

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The Mosaic of Autoimmunity by Yehuda Shoenfeld,David Isenberg Pdf

Author : Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic
Publisher : John Wiley & Sons
Page : 394 pages
File Size : 40,6 Mb
Release : 2015-07-07
Category : Science
ISBN : 9781118663431

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Vaccines and Autoimmunity by Yehuda Shoenfeld,Nancy Agmon-Levin,Lucija Tomljenovic Pdf

In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants – specifically aluminum in different vaccines – and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals. Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor – for instance, systemic lupus erythematosus – and whether it can be induced by vaccines for MMR, HBV, HCV, and others. Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.

Author : Yehuda Shoenfeld
Publisher : Unknown
Page : 523 pages
File Size : 51,5 Mb
Release : 1989
Category : Electronic
ISBN : 0444801626

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The Mosaic of Autoimmunity by Yehuda Shoenfeld Pdf

Author : Yehuda Shoenfeld,Pier Luigi Meroni,M. Eric Gershwin
Publisher : Newnes
Page : 916 pages
File Size : 45,6 Mb
Release : 2013-11-26
Category : Medical
ISBN : 9780444593771

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Autoantibodies by Yehuda Shoenfeld,Pier Luigi Meroni,M. Eric Gershwin Pdf

Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases. Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis Includes clinical applications for each autoantibody along with general information Organized by disease and disorder type, by autoantibody family, and completely cross-referenced

Author : Yehuda Shoenfeld
Publisher : Elsevier
Page : 431 pages
File Size : 52,9 Mb
Release : 1999-02-15
Category : Medical
ISBN : 0080530303

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The Decade of Autoimmunity by Yehuda Shoenfeld Pdf

This book is a direct result of 10 years of the well-known "Autoimmunity Days" in Israel, which are increasingly becoming an international focal point for autoimmunity scientists. Top researchers provide coverage of the most important knowledge generated during the last decade. The volume can therefore be seen almost as a textbook on autoimmunity, projecting from the last decade to the next millennium. A variety of different subjects in autoimmunity, from etiology to pathogenesis, from postulated mechanisms to innovative therapeutic modalities, is handled by noted contributors, while additional authors contribute top papers which significantly enhance a better understanding of autoimmunity. An excellent treatise on the subject, and a worthwhile addition to both clinical and research libraries.

Author : Natalie Gassman
Publisher : Royal Society of Chemistry
Page : 195 pages
File Size : 44,8 Mb
Release : 2022-01-12
Category : Science
ISBN : 9781839162060

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Bisphenol A by Natalie Gassman Pdf

Bisphenol A (BPA) is a high production volume endocrine-disrupting chemical present in numerous consumer products. Extensive use of BPA has led to wide-spread contamination in the air, soil, and water, leading to ubiquitous human exposure. Research into BPA has grown exponentially over the past ten years, with numerous modes of action being identified that impact human health and disease development. While BPA has estrogenic effects, emerging literature has identified several non-receptor mediated modes of action, such as epigenetic reprogramming, that can affect the long-term health of the population. This book highlights the multiple modes of action BPA can use to reprogram cells genetically and metabolically. By compiling critical studies in BPA and outlining the connections and disparities in the literature to build a broader understanding of this complex endocrine-disrupting chemical and its impact on the environment and human health, this book is an ideal resource for postgraduates and researchers in a range of disciplines from toxicology to epigenetics and cancer epidemiology.

Author : Tomohiro Kurosaki,Jürgen Wienands
Publisher : Springer
Page : 231 pages
File Size : 42,7 Mb
Release : 2015-12-26
Category : Medical
ISBN : 9783319261331

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B Cell Receptor Signaling by Tomohiro Kurosaki,Jürgen Wienands Pdf

This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

Author : Susan J. Harkema,Andrea L. Behrman,Hugues Barbeau
Publisher : Oxford University Press, USA
Page : 200 pages
File Size : 49,7 Mb
Release : 2011
Category : Medical
ISBN : 9780195342086

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Locomotor Training by Susan J. Harkema,Andrea L. Behrman,Hugues Barbeau Pdf

Locomotor training is aiming to promote recovery after spinal cord injury via activation of the neuromuscular system below the level of the lesion

Author : Yehuda Shoenfeld,Nancy Agmon-Levin,Noel R Rose
Publisher : Elsevier
Page : 1040 pages
File Size : 43,9 Mb
Release : 2015-01-27
Category : Medical
ISBN : 9780444632722

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Infection and Autoimmunity by Yehuda Shoenfeld,Nancy Agmon-Levin,Noel R Rose Pdf

Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms by which infectious agents can trigger autoimmunity such as molecular mimicry and polyclonal activation. An overview is given with regard to bacteria, viruses, and parasites associated with autoimmunity, and a summary is given on classical autoimmune diseases and the infecting agents that can induce them. Includes completely updated and new chapters Brings the reader up to date and allows easy access to individual topics in one place Identifies infectious agents as pathogenic or protective in many autoimmune diseases

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 46,5 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Author : Runjan Chetty,Kumarasen Cooper,Allen M. Gown
Publisher : Cambridge University Press
Page : 525 pages
File Size : 46,5 Mb
Release : 2016-11-28
Category : Medical
ISBN : 9781107077782

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Leong's Manual of Diagnostic Antibodies for Immunohistology by Runjan Chetty,Kumarasen Cooper,Allen M. Gown Pdf

A detailed, A-Z guide and an indispensable source for pathologists ensuring correct application of immunohistochemistry in daily practice.

Author : Irene Dankwa-Mullan,Eliseo J. Pérez-Stable,Kevin L. Gardner,Xinzhi Zhang,Adelaida M. Rosario
Publisher : John Wiley & Sons
Page : 548 pages
File Size : 42,8 Mb
Release : 2021-03-16
Category : Science
ISBN : 9781119374817

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The Science of Health Disparities Research by Irene Dankwa-Mullan,Eliseo J. Pérez-Stable,Kevin L. Gardner,Xinzhi Zhang,Adelaida M. Rosario Pdf

Integrates the various disciplines of the science of health disparities in one comprehensive volume The Science of Health Disparities Research is an indispensable source of up-to-date information on clinical and translational health disparities science. Building upon the advances in health disparities research over the past decade, this authoritative volume informs policies and practices addressing the diseases, disorders, and gaps in health outcomes that are more prevalent in minority populations and socially disadvantaged communities. Contributions by recognized scholars and leaders in the field—featuring contemporary research, conceptual models, and a broad range of scientific perspectives—provide an interdisciplinary approach to reducing inequalities in population health, encouraging community engagement in the research process, and promoting social justice. In-depth chapters help readers better understand the specifics of minority health and health disparities while demonstrating the importance of advancing theory, refining measurement, improving investigative methods, and diversifying scientific research. In 26 chapters, the book examines topics including the etiology of health disparities research, the determinants of population health, research ethics, and research in African American, Asians, Latino, American Indian, and other vulnerable populations. Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research Explains basic definitions, principles, and concepts for identifying, understanding and addressing health disparities Provides guidance on both conducting health disparities research and translating the results Examines how social, historical and contemporary injustices may influence the health of racial and ethnic minorities Illustrates the increasing national and global importance of addressing health disparities Discusses population health training, capacity-building, and the transdisciplinary tools needed to advance health equity A significant contribution to the field, The Science of Health Disparities Research is an essential resource for students and basic and clinical researchers in genetics, population genetics, and public health, health care policymakers, and epidemiologists, medical students, and clinicians, particularly those working with minority, vulnerable, or underserved populations.