The Neuroscience Of Spinal Cord Injury

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The Neuroscience of Spinal Cord Injury-

Rajkumar Rajendram,Victor R Preedy,Colin R Martin
The Neuroscience of Spinal Cord Injury Book PDF

Author : Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Publisher : Academic Press
Page : 1186 pages
File Size : 41,5 Mb
Release : 2022-05-27
Category : Medical
ISBN : 9780323995764

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The Neuroscience of Spinal Cord Injury- by Rajkumar Rajendram,Victor R Preedy,Colin R Martin Pdf

Diagnosis and Treatment of Spinal Cord Injury will enhance readers’ understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries. Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Diagnosis and Treatment of Spinal Cord Injury: Covers both the diagnosis and treatment of spinal cord injury Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on epidemiology and pain Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury Discusses pain reduction, drug delivery, and rehabilitation Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury: Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Diagnosis and Treatment of Spinal Cord Injury

Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Diagnosis and Treatment of Spinal Cord Injury Book PDF

Author : Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Publisher : Academic Press
Page : 628 pages
File Size : 54,6 Mb
Release : 2022-05-10
Category : Medical
ISBN : 9780128224991

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Diagnosis and Treatment of Spinal Cord Injury by Rajkumar Rajendram,Victor R Preedy,Colin R Martin Pdf

Diagnosis and Treatment of Spinal Cord Injury will enhance readers’ understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries. Covers both the diagnosis and treatment of spinal cord injury Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on epidemiology and pain Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury Discusses pain reduction, drug delivery, and rehabilitation

Spinal Cord Injury

Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Spinal Cord Injury
Spinal Cord Injury Book PDF

Author : Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Spinal Cord Injury
Publisher : National Academies Press
Page : 360 pages
File Size : 49,7 Mb
Release : 2005-07-27
Category : Medical
ISBN : 9780309165204

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Spinal Cord Injury by Institute of Medicine,Board on Neuroscience and Behavioral Health,Committee on Spinal Cord Injury Pdf

An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are still no cures and the challenge of restoring function in the wake of spinal cord injuries remains extremely complex. Spinal Cord Injury examines the future directions for research with the goal to accelerate the development of cures for spinal cord injuries. While many of the recommendations are framed within the context of the specific needs articulated by the New York Spinal Cord Injury Research Board, the Institute of Medicine's panel of experts looked very broadly at research priorities relating to future directions for the field in general and make recommendations to strengthen and coordinate the existing infrastructure. Funders at federal and state agencies, academic organizations, pharmaceutical and device companies, and non-profit organizations will all find this book to be an essential resource as they examine their opportunities.

Neurobiology of Spinal Cord Injury

Robert G. Kalb,Stephen M. Strittmatter
Neurobiology of Spinal Cord Injury Book PDF

Author : Robert G. Kalb,Stephen M. Strittmatter
Publisher : Springer Science & Business Media
Page : 293 pages
File Size : 50,7 Mb
Release : 1999-10-22
Category : Medical
ISBN : 9781592592005

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Neurobiology of Spinal Cord Injury by Robert G. Kalb,Stephen M. Strittmatter Pdf

Distinguished researchers review the latest scientific understanding of spinal cord injury (SCI), focusing on the mechanisms causing paralysis after spinal cord trauma, the molecular determinants of neural regeneration, and methods for improving damaged function. The authors examine the role of intracellular Ca2+ in neuronal death, the possibility of spinal learning, growth-promoting molecules for regenerating neurons, and the biochemistry and cell biology of microtubules. Among the treatment possibilities discussed are cell transplantation strategies beyond the use of fetal spinal cord tissue, remyelination in spinal cord demyelination models, high steroid therapy immediately after SCI, and the mixed use of anti- and proinflammatories. Comprehensive and highly promising, Neurobiology of Spinal Cord Injury summarizes and integrates the great progress that has been made in understanding and combating the paralysis that follows spinal cord injury.

Spinal Cord Injury

Joost Verhaagen,John W. McDonald III
Spinal Cord Injury Book PDF

Author : Joost Verhaagen,John W. McDonald III
Publisher : Newnes
Page : 656 pages
File Size : 49,5 Mb
Release : 2012-12-31
Category : Medical
ISBN : 9780444535078

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Spinal Cord Injury by Joost Verhaagen,John W. McDonald III Pdf

Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological approaches, molecular target discovery, and the use of olfactory ensheathing cells, stem cells, and precursor cells. Organized in five sections, the book begins with an overview of the development, maturation, biomechanics, and anatomy of the spinal cord before proceeding with a discussion of clinical diagnosis and prognosis as well as natural recovery, ambulation, and function following spinal cord injury. It then examines clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; medical, surgical and rehabilitative management of spinal cord trauma; and some new approaches for improving recovery in patients, including restoration of function by electrical stimulation, locomotor training, and the use of robotics. Other chapters cover cell transplantation, artificial scaffolds, experimental pharmacological interventions, and molecular and combinatorial strategies for repairing the injured spinal cord. This volume should be of interest to neuroscience and clinical neurology research specialists and practicing neurologists. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities

Spinal Cord Injury

Joost Verhaagen,John W. McDonald,John W. McDonald, III
Spinal Cord Injury Book PDF

Author : Joost Verhaagen,John W. McDonald,John W. McDonald, III
Publisher : Newnes
Page : 678 pages
File Size : 53,5 Mb
Release : 2012-11-21
Category : Medical
ISBN : 9780444521378

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Spinal Cord Injury by Joost Verhaagen,John W. McDonald,John W. McDonald, III Pdf

Spinal Cord Injury, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury.

Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury

Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Cellular Molecular Physiological and Behavioral Aspects of Spinal Cord Injury Book PDF

Author : Rajkumar Rajendram,Victor R Preedy,Colin R Martin
Publisher : Academic Press
Page : 558 pages
File Size : 41,7 Mb
Release : 2022-05-10
Category : Medical
ISBN : 9780128224281

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Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury by Rajkumar Rajendram,Victor R Preedy,Colin R Martin Pdf

Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers’ understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding Features chapters on signaling and hormonal events Includes plasticity and gene expression Examines health and stress behaviors after spinal cord injury

Spinal Cord Injury

Michael E. Selzer
Spinal Cord Injury Book PDF

Author : Michael E. Selzer
Publisher : ReadHowYouWant.com
Page : 254 pages
File Size : 47,9 Mb
Release : 2010
Category : Health & Fitness
ISBN : 9781458763310

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Spinal Cord Injury by Michael E. Selzer Pdf

SPINAL CORD INJURY A GUIDE FOR PATIENTS AND FAMILIES The newest title in the critically acclaimed American Academy of Neurology Press Quality of Life Guides series, Spinal Cord Injury is an authoritative and reliable resource for all those looking to educate themselves on the topic of spinal cord injury (SCI). Written in easy-to-understand language, the book includes information on: How the spinal cord works and what happens when it is injured; The benefits of rehabilitation; Assistive devices that can make life easier; A glossary with commonly used terms for communicating with doctors and caregivers; Website resources that can aid in further research Learning to live with a spinal cord injury can be a challenge. This book will help people better understand the medical basis for their disabilities, the current treatments and rehabilitative methods used to manage spinal cord injuries, and the research that points to hope for the future. About the Authors Michael E. Selzer, MD, PhD, is a professor in the Department of Neurology and director of the Center for Experimental Neurorehabilitation Training at the University of Pennsylvania School of Medicine, as well as director of Rehabilitation Research and Development in the Department of Veterans Affairs.

Restorative Neurology of Spinal Cord Injury

Milan R. Dimitrijevic,Byron A. Kakulas,W. Barry McKay
Restorative Neurology of Spinal Cord Injury Book PDF

Author : Milan R. Dimitrijevic,Byron A. Kakulas,W. Barry McKay
Publisher : OUP USA
Page : 337 pages
File Size : 42,7 Mb
Release : 2012-01-12
Category : Medical
ISBN : 9780199746507

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Restorative Neurology of Spinal Cord Injury by Milan R. Dimitrijevic,Byron A. Kakulas,W. Barry McKay Pdf

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach. Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.

Neurological Aspects of Spinal Cord Injury

Norbert Weidner,Rüdiger Rupp,Keith E. Tansey
Neurological Aspects of Spinal Cord Injury Book PDF

Author : Norbert Weidner,Rüdiger Rupp,Keith E. Tansey
Publisher : Springer
Page : 770 pages
File Size : 51,9 Mb
Release : 2017-06-06
Category : Medical
ISBN : 9783319462936

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Neurological Aspects of Spinal Cord Injury by Norbert Weidner,Rüdiger Rupp,Keith E. Tansey Pdf

This clinically focused book aims to cover for the first time all of the neurological aspects relevant to the diagnosis and treatment of spinal cord disease. Furthermore, innovative neurorestorative therapeutic strategies - aiming for repair of the damaged spinal cord and/or reorganization of the remaining nervous system - with significant potential for translation into clinical routine are presented. The book covers a comprehensive list of topics, including epidemiology, neuroanatomy, etiology of compressive and non-compressive spinal cord injury, imaging, neurophysiology, neurological sequelae, and complications with emphasis on dysfunction of the autonomic nervous system. Both clinically established and preclinical therapies are discussed in detail. The book is suited for trainees and practicing clinicians including neurologists, spine surgeons, rehabilitation specialists, neuroradiologists, and occupational/physical therapists; it will also be of value to neuroscientists involved in research into spinal cord disease.

Traumatic Brain and Spinal Cord Injury

Cristina Morganti-Kossmann,Ramesh Raghupathi,Andrew Maas
Traumatic Brain and Spinal Cord Injury Book PDF

Author : Cristina Morganti-Kossmann,Ramesh Raghupathi,Andrew Maas
Publisher : Cambridge University Press
Page : 361 pages
File Size : 45,8 Mb
Release : 2012-07-19
Category : Medical
ISBN : 9781107007437

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Traumatic Brain and Spinal Cord Injury by Cristina Morganti-Kossmann,Ramesh Raghupathi,Andrew Maas Pdf

Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Karolinska Institutet 200-Year Anniversary Symposium on Injuries to the Spinal Cord and Peripheral Nervous System - An Update on Recent Advances in Regenerative Neuroscience

Mattias K. Sköld,Michael G. Fehlings
Karolinska Institutet 200 Year Anniversary Symposium on Injuries to the Spinal Cord and Peripheral Nervous System An Update on Recent Advances in Regenerative Neuroscience Book PDF

Author : Mattias K. Sköld,Michael G. Fehlings
Publisher : Frontiers Media SA
Page : 76 pages
File Size : 55,8 Mb
Release : 2017-11-08
Category : Electronic book
ISBN : 9782889453245

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Karolinska Institutet 200-Year Anniversary Symposium on Injuries to the Spinal Cord and Peripheral Nervous System - An Update on Recent Advances in Regenerative Neuroscience by Mattias K. Sköld,Michael G. Fehlings Pdf

The present E-book consists of original articles and reviews published in our Research Topic on injuries to the spinal cord and peripheral nerves and presents a wide array of novel findings and in depth discussions on topics within the field of nerve injury and repair. Our aim with this Research Topic is to bring together knowledge spanning from basic laboratory studies to clinical findings and strategies within the field of spinal cord and nerve injury and repair. We hope this publication will provide a basis for accelerated knowledge exchange within the field and hopefully a subsequent increase in research efforts and collaborations.

Essentials of Spinal Cord Injury Medicine

Yannis Dionyssiotis
Essentials of Spinal Cord Injury Medicine Book PDF

Author : Yannis Dionyssiotis
Publisher : BoD – Books on Demand
Page : 168 pages
File Size : 49,7 Mb
Release : 2018-06-13
Category : Medical
ISBN : 9781789232486

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Essentials of Spinal Cord Injury Medicine by Yannis Dionyssiotis Pdf

Spinal cord injury is a severe condition leading to serious neurological dysfunctions and changes a person's life in a sudden way. Understanding the pathophysiology of spinal cord injury will improve the prognosis and reintegration to the society of spinal cord-injured subjects. The book Essentials in Spinal Cord Injury Medicine includes seven chapters with valuable information addressing hot topics related to spinal cord injury, ranging from pathophysiology, nontraumatic spinal cord injury, complications to exoskeletons, and research therapies with mesenchymal stem cells. The book could be a valued reference for physiatrists, neurosurgeons, orthopedic surgeons, neurologists and physical therapists.

Spinal Cord Injury

Anders Holtz, MD, PhD,Richard Levi, MD, PhD
Spinal Cord Injury Book PDF

Author : Anders Holtz, MD, PhD,Richard Levi, MD, PhD
Publisher : Oxford University Press
Page : 336 pages
File Size : 40,7 Mb
Release : 2010-07-20
Category : Medical
ISBN : 0199706816

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Spinal Cord Injury by Anders Holtz, MD, PhD,Richard Levi, MD, PhD Pdf

Spinal cord injuries typically strike young, previously healthy persons, and leaves the individual with a severe, life-lasting impairment affecting all organ systems. Without adequate management, the risk of severe morbidity and mortality is very high. In contrast state-of-the-art management makes it possible for most persons with SCI to lead long, fulfilling, and autonomous lives despite neurological impairment. This book covers all medical and surgical aspects of modern SCI management from the scene of the accident through rehabilitation to the life-long follow up.

Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury

Donald G. Stein,Bernhard A. Sabel
Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury Book PDF

Author : Donald G. Stein,Bernhard A. Sabel
Publisher : Springer Science & Business Media
Page : 400 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461309277

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Pharmacological Approaches to the Treatment of Brain and Spinal Cord Injury by Donald G. Stein,Bernhard A. Sabel Pdf

Although there are over 400,000 people each year in the United States alone who suffer from traumatic injury to the central nervous system (CNS), no phar macological treatment is currently available. Considering the enormity of the problem in terms of human tragedy as well as the economic burden to families and societies alike, it is surprising that so little effort is being made to develop treatments for these disorders. Although no one can become inured to the victims of brain or spinal cord injuries, one reason that insufficient time and effort have been devoted to research on recovery is that it is a generally held medical belief that nervous system injuries are simply not amenable to treatment. At best, current therapies are aimed at providing symptomatic relief or focus on re habilitative measures and the teaching of alternative behavioral strategies to help patients cope with their impairments, with only marginal results in many cases. Only within the last decade have neuroscientists begun to make serious inroads into understanding and examining the inherent "plasticity" found in the adult CNS. Ten years or so ago, very few researchers or clinicians would have thought that damaged central neurons could sprout new terminals or that intact nerve fibers in a damaged pathway could proliferate to replace inputs from neurons that died as a result of injury.