The Oxford Handbook Of Neuronal Ion Channels

Author : Arin Bhattacharjee
Publisher : Oxford University Press
Page : 785 pages
File Size : 54,5 Mb
Release : 2023-01-02
Category : Electronic
ISBN : 9780190669164

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The Oxford Handbook of Neuronal Ion Channels by Arin Bhattacharjee Pdf

Neurons are excitable cells. They use ions and electrical signaling to talk to each to other and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons. The book explains how ion channels open and close, how they can be selective for specific ions, and how they give rise to action potentials. Included are in-depth chapters discussing specific classes of ion channels: potassium channels, sodium channels, neurotransmitter-gated ion channels and other specialized channels. Throughout the handbook, important insight is provided on the contribution ion channels make to neuronal excitability and to synaptic transmission. The handbook goes further to discuss channelopathies, a group of human diseases such as epilepsy, pain and migraines that can be caused by ion channel dysfunction. For neuroscientists, biophysicists and neuropharmacologists, this handbook is a valuable reference of ion channel biology and function.

Author : Arin Bhattacharjee
Publisher : Unknown
Page : 0 pages
File Size : 43,5 Mb
Release : 2022
Category : Electronic books
ISBN : 0190669187

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The Oxford Handbook of Neuronal Ion Channels by Arin Bhattacharjee Pdf

Neurons are excitable cells. They use ions and electrical signaling to talk to each to other and when they talk to each other, neurons control behavior. The Oxford Handbook of Neuronal Ion Channels is an accessible reference describing the nature and properties of ion channels in neurons.

Author : Irwin B. Levitan,Leonard K. Kaczmarek
Publisher : Oxford University Press, USA
Page : 640 pages
File Size : 43,5 Mb
Release : 2002
Category : Molecular neurobiology
ISBN : 0195145232

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The Neuron by Irwin B. Levitan,Leonard K. Kaczmarek Pdf

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Author : Anonim
Publisher : Academic Press
Page : 454 pages
File Size : 46,5 Mb
Release : 2021-06-12
Category : Science
ISBN : 9780128239254

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Ion Channels: Channel Chemical Biology, Engineering, and Physiological Function by Anonim Pdf

Ion Channels, Part C, Volume 653 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Nonsense suppression in ion channels, Engineering Ion Channels Using Protein Trans-splicing, Probing Ion Channel Neighborhoods Using APEX, STX based probes for NaVs, ANAP: a versatile, fluorescent probe of ion channel gating and regulation, High Throughput Screens for Small Molecule Ion Channel Modulators, Using toxins to study ion channels, Re/de-constructing ubiquitin regulation of ion channels, Tethered Peptide Toxins for Ion Channels, Voltage-Sensing Phosphatase Molecular Engineering, and more. Additional chapters cover Engineering excitable cells, Stretch and Poke Stimulation of Mechanically-Activated Ion Channels, Optical Control of STIM Channels, High Throughput Electrophysiological Evaluation of Mutant Ion Channels, Evaluating BEST1 Mutations in RPE Stem Cells, Long Read Transcript Profiling of Ion Channel Splice Variants, Permeation of Connexin Channels, Ratiometric pH indicator for melanosomes and lysosomes, and Ion channels in the epithelial cells of the choroid plexus. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series

Author : Karl Kandler PhD
Publisher : Oxford University Press
Page : 512 pages
File Size : 54,7 Mb
Release : 2019-08-22
Category : Science
ISBN : 9780190849085

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The Oxford Handbook of the Auditory Brainstem by Karl Kandler PhD Pdf

The Oxford Handbook of The Auditory Brainstem provides an introduction as well as an in-depth reference to the organization and function of ascending and descending auditory pathways in the mammalian brainstem. Individual chapters are organized along the auditory pathway beginning with the cochlea and ending with the auditory midbrain. Each chapter provides an introduction to the respective area, and summarizes our current knowledge before discussing disputes and challenges the field currently faces. A major emphasis throughout this book is on the numerous forms of plasticity that are increasingly observed in many areas of the auditory brainstem. Several chapters focus on neuronal modulation of function and synaptic, neuronal, and circuit plasticity, especially under circumstances when they occur most prominently: during development, aging, and following peripheral hearing loss. In addition, the book addresses the role of trauma-induced maladaptive plasticity with respect to its contribution in generating central hearing dysfunction such as hyperacusis and tinnitus. The book is intended for students and postdocs starting in the auditory field, and researchers of related fields who wish to get an authoritative and up-to-date summary of the current state of auditory brainstem research. For clinical practitioners in audiology, otolaryngology, and neurology, the book is a valuable resource of information about the neuronal mechanisms that are major candidates for the generation of central hearing dysfunction.

Author : Bertil Hille
Publisher : Sinauer Associates, Incorporated
Page : 632 pages
File Size : 41,7 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015024124383

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Ionic Channels of Excitable Membranes by Bertil Hille Pdf

This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.

Author : Leonard K. Kaczmarek,Irwin B. Levitan
Publisher : Oxford University Press, USA
Page : 316 pages
File Size : 48,6 Mb
Release : 1987
Category : Medical
ISBN : 019504097X

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Neuromodulation by Leonard K. Kaczmarek,Irwin B. Levitan Pdf

This volume provides an introduction to the general principles of neuromodulation--the key neurobiological process for understanding how the brain works. Emphasizing ion channels and biochemical mechanisms of protein phosphorylation, the book shows how neurons regulate their intracellular calcium concentration by modulating the activity of certain ion channels. It goes on to explain the function of intracellular calcium and describes some fascinating neuromodulatory phenomena in the mammalian brain that have long awaited the kind of mechanistic investigations possible in simpler systems. Bridging the gap between neurochemistry and neurophysiology, the authors make complex concepts and research approaches comprehensible to scientists in either field.

Author : John N. Wood
Publisher : Oxford University Press, USA
Page : 939 pages
File Size : 47,5 Mb
Release : 2020
Category : Medical
ISBN : 9780190860509

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The Oxford Handbook of the Neurobiology of Pain by John N. Wood Pdf

This handbook is currently in development, with individual articles publishing online in advance of print publication. At this time, we cannot add information about unpublished articles in this handbook, however the table of contents will continue to grow as additional articles pass through the review process and are added to the site. Please note that the online publication date for this handbook is the date that the first article in the title was published online.

Author : Karl Kandler
Publisher : Oxford University Press, USA
Page : 825 pages
File Size : 42,9 Mb
Release : 2019
Category : Medical
ISBN : 9780190849061

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The Oxford Handbook of the Auditory Brainstem by Karl Kandler Pdf

The Oxford Handbook of The Auditory Brainstem provides an introduction as well as an in-depth reference to the organization and function of ascending and descending auditory pathways in the mammalian brainstem. Individual chapters are organized along the auditory pathway beginning with the cochlea and ending with the auditory midbrain. Each chapter provides an introduction to the respective area, and summarizes our current knowledge before discussing disputes and challenges the field currently faces. A major emphasis throughout this book is on the numerous forms of plasticity that are increasingly observed in many areas of the auditory brainstem. Several chapters focus on neuronal modulation of function and synaptic, neuronal, and circuit plasticity, especially under circumstances when they occur most prominently: during development, aging, and following peripheral hearing loss. In addition, the book addresses the role of trauma-induced maladaptive plasticity with respect to its contribution in generating central hearing dysfunction such as hyperacusis and tinnitus. The book is intended for students and postdocs starting in the auditory field, and researchers of related fields who wish to get an authoritative and up-to-date summary of the current state of auditory brainstem research. For clinical practitioners in audiology, otolaryngology, and neurology, the book is a valuable resource of information about the neuronal mechanisms that are major candidates for the generation of central hearing dysfunction.

Author : Professor John N. Wood
Publisher : Oxford University Press
Page : 512 pages
File Size : 40,6 Mb
Release : 2020-06-17
Category : Science
ISBN : 9780190860523

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The Oxford Handbook of the Neurobiology of Pain by Professor John N. Wood Pdf

The Oxford Handbook of the Neurobiology of Pain represents a state of the art overview of the rapidly developing field of pain research. As populations age, the number of people in pain is growing dramatically, with half the population living with pain. The opioid crisis has highlighted this problem. The present volume is thus very timely, providing expert overviews of many complex topics in pain research that are likely to be of interest not just to pain researchers, but also to pain clinicians who are seeking new therapeutic opportunities to develop analgesics. Many of the topics covered are of interest to neuroscientists, as pain is one of the most amenable sensations for mechanistic dissection. The present volume covers all aspects of the topic, from a history of pain through invertebrate model systems to the human genetics of pain and functional imaging. Chapters include the role of ion channels, the opioid system, the immune and sympathetic systems, as well as the mechanisms that transform acute to chronic pain. Migraine and the interplay between sleep and pain are also discussed. New technology in the form of transgenic animals, chemogenetics, optogenetics, and proteomic analyses are providing significant advances in our research and are covered as well. Demystifying pain through an understanding of its fundamental biology, as outlined in this volume, is the most direct route to ameliorating this vast human problem.

Author : Achim Klug,Leonard Kaczmarek,Elizabeth Anne McCullagh,Dan Tollin
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 43,9 Mb
Release : 2022-05-09
Category : Science
ISBN : 9782889761593

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Alterations in the Sound Localization Pathway Related to Impaired Cocktail-Party Performance by Achim Klug,Leonard Kaczmarek,Elizabeth Anne McCullagh,Dan Tollin Pdf

Author : Enrique Soto,Candice Askwith,Osvaldo D. Uchitel,Chih-Cheng Chen,David MacLean
Publisher : Frontiers Media SA
Page : 123 pages
File Size : 40,6 Mb
Release : 2022-02-28
Category : Science
ISBN : 9782889745500

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ASICs: Structure, Function, and Pharmacology by Enrique Soto,Candice Askwith,Osvaldo D. Uchitel,Chih-Cheng Chen,David MacLean Pdf

Author : Christopher L.-H. Huang
Publisher : Cambridge University Press
Page : 327 pages
File Size : 44,5 Mb
Release : 2020-11-19
Category : Medical
ISBN : 9781108495059

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Keynes & Aidley's Nerve and Muscle by Christopher L.-H. Huang Pdf

Editions previous to this one had R.D. Keynes and David J. Aidley as primary and secondary authors.

Author : Joan Y. Chiao,Shu Chen Li,Robert Turner,Su Yeon Lee-Tauler,Beverly Pringle
Publisher : Oxford University Press
Page : 673 pages
File Size : 52,7 Mb
Release : 2022-02-28
Category : Medical
ISBN : 9780190057695

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The Oxford Handbook of Cultural Neuroscience and Global Mental Health by Joan Y. Chiao,Shu Chen Li,Robert Turner,Su Yeon Lee-Tauler,Beverly Pringle Pdf

"The Oxford Handbook of Cultural Neuroscience and Global Mental Health provides a substantive and in-depth overview of the study of cultural neuroscience and global mental health. Theory, methods and evidence-based practices are reviewed and integrated across themes that identify ethical, scientific, and health care issues for distinct populations across nations. The international research collaboration in the field of cultural neuroscience and global mental health provides research and training opportunities for global mental health researchers. Future research and training in the field seeks the achievement of the amelioration of disease and fulfillment of the goal to alleviate the unmet societal needs due to the global burden of disease"--

Author : Anonim
Publisher : Academic Press
Page : 2390 pages
File Size : 51,6 Mb
Release : 2020-06-26
Category : Science
ISBN : 9780128140826

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Encyclopedia of Bone Biology by Anonim Pdf

Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles. Incorporates perspectives from experts working within the domains of biomedicine, including physiology, pathobiology, pharmacology, immunology, endocrinology, orthopedics and metabolism Provides an authoritative introduction for non-specialists and readers from undergraduate level upwards, as well as up-to-date foundational content for those familiar with the field Includes multimedia features, cross-references and color images/videos