Theoretical Biochemistry

Author : Leif A. Eriksson
Publisher : Elsevier
Page : 719 pages
File Size : 53,7 Mb
Release : 2001-02-19
Category : Science
ISBN : 9780080542706

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Theoretical Biochemistry by Leif A. Eriksson Pdf

Theoretical chemistry has been an area of tremendous expansion and development over the past decade; from an approach where we were able to treat only a few atoms quantum mechanically or make fairly crude molecular dynamics simulations, into a discipline with an accuracy and predictive power that has rendered it an essential complementary tool to experiment in basically all areas of science. This volume gives a flavour of the types of problems in biochemistry that theoretical calculations can solve at present, and illustrates the tremendous predictive power these approaches possess.A wide range of computational approaches, from classical MD and Monte Carlo methods, via semi-empirical and DFT approaches on isolated model systems, to Car-Parinello QM-MD and novel hybrid QM/MM studies are covered. The systems investigated also cover a broad range; from membrane-bound proteins to various types of enzymatic reactions as well as inhibitor studies, cofactor properties, solvent effects, transcription and radiation damage to DNA.

Author : Hans Netter
Publisher : Unknown
Page : 972 pages
File Size : 46,7 Mb
Release : 1969
Category : Biochemistry
ISBN : UCAL:B4494556

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Theoretical Biochemistry by Hans Netter Pdf

Author : David L. Beveridge,Richard Lavery
Publisher : Adenine Press, Incorporated
Page : 462 pages
File Size : 51,5 Mb
Release : 1991
Category : Biochemistry
ISBN : 0940030284

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Theoretical Biochemistry & Molecular Biophysics by David L. Beveridge,Richard Lavery Pdf

Author : A. Pullman
Publisher : Springer Science & Business Media
Page : 390 pages
File Size : 40,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400995130

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Catalysis in Chemistry and Biochemistry Theory and Experiment by A. Pullman Pdf

Proceedings of the Twelfth Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, April 2-4, 1979

Author : David E. Metzler,Carol M. Metzler
Publisher : Academic Press
Page : 968 pages
File Size : 46,5 Mb
Release : 2001-03-23
Category : Medical
ISBN : 9780124925403

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Biochemistry by David E. Metzler,Carol M. Metzler Pdf

Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.

Author : Zvonimir B. Maksic
Publisher : Springer Science & Business Media
Page : 462 pages
File Size : 51,6 Mb
Release : 2013-03-07
Category : Science
ISBN : 9783642581830

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Theoretical Treatment of Large Molecules and Their Interactions by Zvonimir B. Maksic Pdf

The French chemist Marcelin Berthelot put forward a classical and by now an often cited sentence revealing the quintessence of the chemical science: "La Chimie cree son objet". This is certainly true because the largest number of molecular compounds were and are continuously synthesized by chemists themselves. However, modern computational quantum chemistry has reached a state of maturity that one can safely say: "La Chimie Theorique cree son objet" as well. Indeed, modern theoretical chemistry is able today to provide reliable results on elusive systems such as short living species, reactive intermediates and molecules which will perhaps never be synthesized because of one or another type of instability. It is capable of yielding precious information on the nature of the transition states, reaction paths etc. Additionally, computational chemistry gives some details of the electronic and geometric structure of molecules which remain hidden in experimental examinations. Hence, it follows that powerful numerical techniques have substantially enlarged the domain of classical chemistry. On the other hand, interpretive quantum chemistry has provided a conceptual framework which enabled rationalization and understanding of the precise data offered either by experiment or theory. It is modelling which gives a penetrating insight into the chemical phenomena and provides order in raw experimental results which would otherwise represent just a large catalogue of unrelated facts.

Author : Raj Kumar,Bal Ram Singh
Publisher : Springer
Page : 145 pages
File Size : 51,7 Mb
Release : 2016-11-21
Category : Science
ISBN : 9783319435404

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Protein Toxins in Modeling Biochemistry by Raj Kumar,Bal Ram Singh Pdf

This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science.

Author : Chérif F. Matta
Publisher : John Wiley & Sons
Page : 978 pages
File Size : 42,9 Mb
Release : 2010-01-14
Category : Science
ISBN : 9783527629220

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Quantum Biochemistry by Chérif F. Matta Pdf

Divided into five major parts, the two volumes of this ready reference cover the tailoring of theoretical methods for biochemical computations, as well as the many kinds of biomolecules, reaction and transition state elucidation, conformational flexibility determination, and drug design. Throughout, the chapters gradually build up from introductory level to comprehensive reviews of the latest research, and include all important compound classes, such as DNA, RNA, enzymes, vitamins, and heterocyclic compounds. The result is in-depth and vital knowledge for both readers already working in the field as well as those entering it. Includes contributions by Prof. Ada Yonath (Nobel Prize in Chemistry 2009) and Prof. Jerome Karle (Nobel Prize in Chemistry 1985).

Author : Oren M. Becker,Alexander D. MacKerell Jr.,Benoit Roux,Masakatsu Watanabe
Publisher : CRC Press
Page : 534 pages
File Size : 40,7 Mb
Release : 2001-02-09
Category : Medical
ISBN : 020390382X

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Computational Biochemistry and Biophysics by Oren M. Becker,Alexander D. MacKerell Jr.,Benoit Roux,Masakatsu Watanabe Pdf

Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret b

Author : Sadasivan Shankar,Richard Muller,Thom Dunning,Guan Hua Chen
Publisher : Springer Nature
Page : 1344 pages
File Size : 49,5 Mb
Release : 2021-01-25
Category : Technology & Engineering
ISBN : 9783030187781

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Computational Materials, Chemistry, and Biochemistry: From Bold Initiatives to the Last Mile by Sadasivan Shankar,Richard Muller,Thom Dunning,Guan Hua Chen Pdf

This book provides a broad and nuanced overview of the achievements and legacy of Professor William (“Bill”) Goddard in the field of computational materials and molecular science. Leading researchers from around the globe discuss Goddard’s work and its lasting impacts, which can be seen in today’s cutting-edge chemistry, materials science, and biology techniques. Each section of the book closes with an outline of the prospects for future developments. In the course of a career spanning more than 50 years, Goddard’s seminal work has led to dramatic advances in a diverse range of science and engineering fields. Presenting scientific essays and reflections by students, postdoctoral associates, collaborators and colleagues, the book describes the contributions of one of the world’s greatest materials and molecular scientists in the context of theory, experimentation, and applications, and examines his legacy in each area, from conceptualization (the first mile) to developments and extensions aimed at applications, and lastly to de novo design (the last mile). Goddard’s passion for science, his insights, and his ability to actively engage with his collaborators in bold initiatives is a model for us all. As he enters his second half-century of scientific research and education, this book inspires future generations of students and researchers to employ and extend these powerful techniques and insights to tackle today’s critical problems in biology, chemistry, and materials. Examples highlighted in the book include new materials for photocatalysts to convert water and CO2 into fuels, novel catalysts for the highly selective and active catalysis of alkanes to valuable organics, simulating the chemistry in film growth to develop two-dimensional functional films, and predicting ligand–protein binding and activation to enable the design of targeted drugs with minimal side effects.

Author : Anonim
Publisher : Elsevier
Page : 330 pages
File Size : 49,9 Mb
Release : 2006-11-14
Category : Technology & Engineering
ISBN : 0080466788

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Theoretical Aspects of Chemical Reactivity by Anonim Pdf

Theoretical Aspects of Chemical Reactivity provides a broad overview of recent theoretical and computational advancements in the field of chemical reactivity. Contributions have been made by a number of leaders in the field covering theoretical developments to applications in molecular systems and clusters. With an increase in the use of reactivity descriptors, and fundamental theoretical aspects becoming more challenging, this volume serves as an interesting overview where traditional concepts are revisited and explored from new viewpoints, and new varieties of reactivity descriptors are proposed. Includes applications in the frontiers of reactivity principles, and introduces dynamic and statistical viewpoints to chemical reactivity and challenging traditional concepts such as aromaticity. * Written by specialists in the field of chemical reactivity * An authoritative overview of the research and progress * An essential reference material for students

Author : William Robert Fearon
Publisher : Elsevier
Page : 488 pages
File Size : 47,5 Mb
Release : 2014-05-12
Category : Science
ISBN : 9781483225395

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An Introduction to Biochemistry by William Robert Fearon Pdf

An Introduction to Biochemistry, Second Edition provides information pertinent to the fundamental aspects of biochemistry. This book presents several analytical methods, including the citrulline reaction for proteins and the diffusion test for acetone. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the general composition of the organism and the chemical characteristics of the chief organic and inorganic compounds that enter into its structure. This text then examines the chemical composition of the tissues and physiological systems. Other chapters consider the occurrence and identification of several pathological constituents of urine, which presents features of biochemical interest. This book discusses as well the significance and analytical reactions of the bile acids and esters. The final chapter deals with the internal environment, which in the higher animal is represented by the blood and the cerebrospinal and other tissue fluids. This book is a valuable resource for biochemists.

Author : William John Edward Jessop
Publisher : Elsevier
Page : 482 pages
File Size : 47,6 Mb
Release : 2014-05-12
Category : Science
ISBN : 9781483195568

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Fearon's Introduction to Biochemistry by William John Edward Jessop Pdf

Fearon's Introduction to Biochemistry, Fourth Edition provides information pertinent to the fundamental aspects of biochemistry. This book discusses the elements that occur in biological material and the biological properties of water and aqueous solutions. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the classification, distribution, properties, and importance of the constituents of organisms. This text then examines the variable as well as the invariable elements of the biological aspect of all living organisms. Other chapters consider the most important inorganic biochemical compounds, including water, carbon dioxide, carbamates, carbonates, sulfates, silicates, phosphates, fluorides, and chlorides of the biochemical metals. This book discusses as well the chemical reactions associated with life. The final chapter deals with the inherent property of cells for self-construction, which enables them to grow and to preserve their character. This book is a valuable resource for biochemists, biologists, scientists, and research workers.

Author : George Feuer,F. A. de la Iglesia
Publisher : CRC Press
Page : 520 pages
File Size : 48,8 Mb
Release : 2020-04-22
Category : Medical
ISBN : 9781000697780

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Molecular Biochemistry of Human Diseases by George Feuer,F. A. de la Iglesia Pdf

First published in 1986: This book is to help medical, pharmacy, and advanced students in science to understand the growing importance of continuously advancing biochemical concepts in human disease.

Author : Roland K. Hartmann,Albrecht Bindereif,Astrid Schön,Eric Westhof
Publisher : John Wiley & Sons
Page : 1368 pages
File Size : 54,8 Mb
Release : 2015-03-31
Category : Science
ISBN : 9783527650552

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Handbook of RNA Biochemistry by Roland K. Hartmann,Albrecht Bindereif,Astrid Schön,Eric Westhof Pdf

The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.