Thin Layer Chromatography

Author : Elke Hahn-Deinstrop
Publisher : John Wiley & Sons
Page : 330 pages
File Size : 41,6 Mb
Release : 2007-02-27
Category : Science
ISBN : 9783527609857

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Applied Thin-Layer Chromatography by Elke Hahn-Deinstrop Pdf

Thin-layer chromatography (TLC) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This new edition of the practical TLC guide features a completely revised chapter on documentation, now including the use of digital cameras. Selected new sorbents and instruments are also introduced. Why has the prior edition been successful? All steps of the analytical procedure are clearly explained, starting with the choice of a suitable TLC technique and ending with data evaluation and documentation. Special emphasis is put on the proper choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering e. g. precoated layers, solvents and developing chambers, including information on suppliers. Many practical hints for trouble shooting are given. All this is illustrated with numerous coloured figures. How to use TLC in compliance with GLP/GMP regulations is described in detail, including the required documentation. Therefore the reader can very easily compile his own standard operating procedures.

Author : Bernd Spangenberg,Colin F. Poole,Christel Weins
Publisher : Springer Science & Business Media
Page : 399 pages
File Size : 50,8 Mb
Release : 2011-01-03
Category : Science
ISBN : 9783642107290

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Quantitative Thin-Layer Chromatography by Bernd Spangenberg,Colin F. Poole,Christel Weins Pdf

Thin-layer chromatography (TLC) is widely used particularly for pharmaceutical and food analysis. While there are a number of books on the qualitative identification of chemical substances by TLC, the unique focus here is on quantitative analysis. The authors describe all steps of the analytical procedure, beginning with the basics and equipment for quantitative TLC followed by sample pretreatment and sample application, development and staining, scanning, and finally statistical and chemometric data evaluation and validation. An important feature is the coverage of effect-directed biological detection methods. Chapters are organized in a modular fashion facilitating the easy location of information about individual procedural steps.

Author : Egon Stahl
Publisher : Springer Science & Business Media
Page : 1078 pages
File Size : 40,9 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783642884887

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Thin-Layer Chromatography by Egon Stahl Pdf

Author : Ivor Smith,J. W. T. Seakins
Publisher : Elsevier
Page : 476 pages
File Size : 51,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483279923

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Paper and Thin Layer Chromatography by Ivor Smith,J. W. T. Seakins Pdf

Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This book discusses the practical approach in the application of paper and thin layer chromatography techniques in the biological sciences. Organized into 18 chapters, this edition begins with an overview of the clinical aspects related to the detection of those metabolic diseases that can result in serious illness presenting in infancy and early childhood. This text then discusses the three major types of screening for inherited metabolic disorders in which paper or thin-layer chromatography are being used, including screening the healthy newborn population, screening the sick hospitalized child, and screening mentally retarded patients. Other chapters consider the procedures for thin layer chromatography. This book discusses as well the complexity of amino acid mixtures present in natural products. The final chapter deals with the detection of synthetic basic drugs. This book is a valuable resource for chemists and toxicologists.

Author : Monika Waksmundzka-Hajnos,Joseph Sherma,Teresa Kowalska
Publisher : CRC Press
Page : 898 pages
File Size : 50,5 Mb
Release : 2008-03-04
Category : Science
ISBN : 9781420046786

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Thin Layer Chromatography in Phytochemistry by Monika Waksmundzka-Hajnos,Joseph Sherma,Teresa Kowalska Pdf

Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry, biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost make it one of the leading techniques used for locating and analyzing bioactive components in plants. Thin Layer Chromatography in Phytochemistry is the first sourc

Author : Peter E Wall
Publisher : Royal Society of Chemistry
Page : 204 pages
File Size : 54,8 Mb
Release : 2007-10-31
Category : Science
ISBN : 9781847552464

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Thin-Layer Chromatography by Peter E Wall Pdf

Thin-Layer Chromatography (TLC) is a modern, reliable tool that complements other chromatographic techniques. This book provides a practical guide to the basic principles, procedures and pitfalls on the practical application of TLC. Thin Layer Chromatography: A Modern Practical Approach offers a sequence of chapters following the steps of the technique as the chromatographer would follow them. The chapters provide a choice of sorbent best suited to the separation intended, followed by pre-treatment required for the sample, applying the sample to the sorbent layer, development procedure, visualisation and detection, and finally quantification. Imaging and hyphenation techniques are described. The reasons why recommendations are made for specific and more general methods are covered. The book also provides an overview of some recent developments in the field.

Author : Colin Poole
Publisher : Elsevier
Page : 692 pages
File Size : 47,7 Mb
Release : 2023-01-14
Category : Science
ISBN : 9780323983013

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Instrumental Thin-Layer Chromatography by Colin Poole Pdf

Instrumental Thin-Layer Chromatography, Second Edition offers a comprehensive source of authoritative information on all aspects of instrumental thin-layer chromatography. The use of short, topic-focused chapters facilitates identifying information of immediate interest for familiar or emerging uses of thin-layer chromatography. The book gives those working in both academia and industry the opportunity to learn, refresh, or deepen their understanding of fundamental and instrumental aspects of thin-layer chromatography, as well as the tools to interpret and manage chromatographic data. The book serves as a practical consolidated guide to the selection of separation conditions and the use of auxiliary techniques. This fully updated new edition restores the contemporary character of the book for those involved in advancing the technology, analyzing data produced, or applying the technique to new application areas. Some chapters have been consolidated to make room for topics not covered in the first edition, reflecting general changes in the field of thin-layer chromatography, especially in effects-directed detection, convenient interfaces for advanced spectroscopic detection, and greater automation possibilities. This book is a valuable reference for anyone who needs to acquire fundamental and practical information to facilitate progress in research and management functions utilizing information acquired by thin-layer chromatography. Features individual chapters written by recognized authoritative and visionary experts in the field Provides an overview and focused treatment of a single topic Provides tables and diagrams with commonly used data to facilitate practical work, comparison of results, and decision-making Places modern developments in the research literature into a general context not always apparent to inexperienced users of the technique Offers comprehensive updates to all chapters Includes new chapters on instrument platforms, effects-directed detection, data analysis tools, small-scale and microfluidic planar separation systems, and applications to the separation of amino acids and peptides, the analysis of saccharides and lipids, and forensic analysis

Author : Joseph Sherma,Bernard Fried
Publisher : CRC Press
Page : 1356 pages
File Size : 47,7 Mb
Release : 2003-04-18
Category : Science
ISBN : 9780824748661

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Handbook of Thin-Layer Chromatography by Joseph Sherma,Bernard Fried Pdf

In this third edition, more than 40 renowned authorities introduce and update chapters on the theory, fundamentals, techniques, and instrumentation of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC), highlighting the latest procedures and applications of TLC to 19 important compound classes and coverage of TLC applications by compound type. Easily adaptable to industrial scenarios , the Handbook of Thin-Layer Chromatography, Third Edition supports practical research strategies with extensive tables of data, offers numerous figures that illustrate techniques and chromatograms, and includes a glossary as well as a directory of equipment suppliers.

Author : Teresa Kowalska,Joseph Sherma
Publisher : CRC Press
Page : 437 pages
File Size : 41,6 Mb
Release : 2007-06-22
Category : Medical
ISBN : 9780849343964

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Thin Layer Chromatography in Chiral Separations and Analysis by Teresa Kowalska,Joseph Sherma Pdf

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

Author : Joseph C. Touchstone,Murrell F. Dobbins
Publisher : Unknown
Page : 430 pages
File Size : 45,9 Mb
Release : 1983-03
Category : Science
ISBN : MINN:319510004780774

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Practice of Thin Layer Chromatography by Joseph C. Touchstone,Murrell F. Dobbins Pdf

A practical how-to guide to all the basic techniques needed to practice thin layer chromatography in biochemical/pharmaceutical research and quality control. This updated edition presents the most current techniques as well as the hows and whys of TLC. Provides step-by-step methods for performing the separations as well as doing related tasks, such as applying the sample, selecting the mobile phase, and quantitation. Includes a special chapter on how to select solvents for the development of a chromatogram to separate specific individual components of a mixture.

Author : Lukasz Komsta,Monika Waksmundzka-Hajnos,Joseph Sherma
Publisher : CRC Press
Page : 1070 pages
File Size : 50,8 Mb
Release : 2013-12-20
Category : Medical
ISBN : 9781466507159

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Thin Layer Chromatography in Drug Analysis by Lukasz Komsta,Monika Waksmundzka-Hajnos,Joseph Sherma Pdf

Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date, complete reference, Thin Layer Chromatography in Drug Analysis covers the most important methods in pharmaceutical applications of TLC, namely, analysis of bulk drug material and pharmaceutical formulations, degradation studies, analysis of biological samples, optimization of the separation of drug classes, and lipophilicity estimation. The book is divided into two parts. Part I is devoted to general topics related to TLC in the context of drug analysis, including the chemical basis of TLC, sample pleparation, the optimization of layers and mobile phases, detection and quantification, analysis of ionic compounds, and separation and analysis of chiral substances. The text addresses the newest advances in TLC instrumentation, two-dimensional TLC, quantification by slit scanning densitometry and image analysis, statistical processing of data, and various detection and identification methods. It also describes the use of TLC for solving a key issue in the drug market—the presence of substandard and counterfeit pharmaceutical products. Part II provides an in-depth overview of a wide range of TLC applications for separation and analysis of particular drug groups. Each chapter contains an introduction about the structures and medicinal actions of the described substances and a literature review of their TLC analysis. A useful resource for chromatographers, pharmacists, analytical chemists, students, and R&D, clinical, and forensic laboratories, this book can be utilized as a manual, reference, and teaching source.

Author : Sabine Bladt,Eva M. Zgainski
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 44,7 Mb
Release : 2013-11-11
Category : Science
ISBN : 9783662023983

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Plant Drug Analysis by Sabine Bladt,Eva M. Zgainski Pdf

Plant Drug Analysis has proven an invaluable and unique aid for all those involved with drug production and analysis, including pharmacists, chemical and pharmaceutical researchers and technicians, drug importers and exporters, governmental chemical control agencies, and health authorities. From the reviews of the German Edition: "The reviewer would like to recommend this excellent book to all chromatographers, as he considers it highly relevant to the solution of numerous problems. Its main purpose is the demonstration of thin-layer chromatograms of the usual commercial drugs as an aid in testing for identity and purity. ... 165 colour plates, each showing 6 chromatograms and all of superb quality photographs ..." (Journal of Chromatography)

Author : Bernard Fried,Joseph Sherma
Publisher : CRC Press
Page : 294 pages
File Size : 42,5 Mb
Release : 1996-05-29
Category : Science
ISBN : 0849326605

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Practical Thin-Layer Chromatography by Bernard Fried,Joseph Sherma Pdf

Practical Thin-Layer Chromatography provides thorough coverage of the principles, practices, and applications of thin-layer chromatography (TLC) for important sample and compound types. This information is directed specifically at workers in the most active scientific fields.

Author : Friedrich Geiss
Publisher : Unknown
Page : 512 pages
File Size : 51,8 Mb
Release : 1987
Category : Science
ISBN : UOM:39015016083670

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Fundamentals of Thin Layer Chromatography (planar Chromatography) by Friedrich Geiss Pdf

Author : ManMohan Srivastava
Publisher : Springer Science & Business Media
Page : 401 pages
File Size : 48,5 Mb
Release : 2010-11-15
Category : Science
ISBN : 9783642140259

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High-Performance Thin-Layer Chromatography (HPTLC) by ManMohan Srivastava Pdf

The present edited book is the presentation of 18 in-depth national and international contributions from eminent professors, scientists and instrumental chemists from educational institutes, research organizations and industries providing their views on their experience, handling, observation and research outputs on HPTLC, a multi-dimensional instrumentation. The book describes the recent advancements made on TLC which have revolutionized and transformed it into a modern instrumental technique HPTLC. The book addresses different chapters on HPTLC fundamentals: principle, theory, understanding; instrumentation: implementation, optimization, validation, automation and qualitative and quantitative analysis; applications: phytochemical analysis, biomedical analysis, herbal drug quantification, analytical analysis, finger print analysis and potential for hyphenation: HPTLC future to combinatorial approach, HPTLC-MS, HPTLC-FTIR and HPTLC-Scanning Diode Laser. The chapters in the book have been designed in such away that the reader follows each step of the HPTLC in logical order.