Topological Data Analysis For Genomics And Evolution

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Topological Data Analysis for Genomics and Evolution

Raul Rabadan,Andrew J. Blumberg
Topological Data Analysis for Genomics and Evolution Book PDF

Author : Raul Rabadan,Andrew J. Blumberg
Publisher : Cambridge University Press
Page : 522 pages
File Size : 48,5 Mb
Release : 2019-12-19
Category : Science
ISBN : 9781108757492

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Topological Data Analysis for Genomics and Evolution by Raul Rabadan,Andrew J. Blumberg Pdf

Biology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes. Bridging two disciplines, the book is for researchers and graduate students in genomics and evolutionary biology as well as mathematicians interested in applied topology.

Computational Topology for Data Analysis

Tamal Krishna Dey,Yusu Wang
Computational Topology for Data Analysis Book PDF

Author : Tamal Krishna Dey,Yusu Wang
Publisher : Cambridge University Press
Page : 455 pages
File Size : 52,5 Mb
Release : 2022-03-10
Category : Computers
ISBN : 9781009098168

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Computational Topology for Data Analysis by Tamal Krishna Dey,Yusu Wang Pdf

This book provides a computational and algorithmic foundation for techniques in topological data analysis, with examples and exercises.

Topological Data Analysis with Applications

Gunnar Carlsson,Mikael Vejdemo-Johansson
Topological Data Analysis with Applications Book PDF

Author : Gunnar Carlsson,Mikael Vejdemo-Johansson
Publisher : Cambridge University Press
Page : 233 pages
File Size : 53,7 Mb
Release : 2021-12-16
Category : Computers
ISBN : 9781108838658

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Topological Data Analysis with Applications by Gunnar Carlsson,Mikael Vejdemo-Johansson Pdf

This timely text introduces topological data analysis from scratch, with detailed case studies.

Data Analysis and Visualization in Genomics and Proteomics

Francisco Azuaje,Joaquin Dopazo
Data Analysis and Visualization in Genomics and Proteomics Book PDF

Author : Francisco Azuaje,Joaquin Dopazo
Publisher : John Wiley & Sons
Page : 284 pages
File Size : 52,8 Mb
Release : 2005-06-24
Category : Science
ISBN : 9780470094402

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Data Analysis and Visualization in Genomics and Proteomics by Francisco Azuaje,Joaquin Dopazo Pdf

Data Analysis and Visualization in Genomics and Proteomics is the first book addressing integrative data analysis and visualization in this field. It addresses important techniques for the interpretation of data originating from multiple sources, encoded in different formats or protocols, and processed by multiple systems. One of the first systematic overviews of the problem of biological data integration using computational approaches This book provides scientists and students with the basis for the development and application of integrative computational methods to analyse biological data on a systemic scale Places emphasis on the processing of multiple data and knowledge resources, and the combination of different models and systems

Distributed Computing and Intelligent Technology

Stéphane Devismes,Partha Sarathi Mandal,V. Vijaya Saradhi,Bhanu Prasad,Anisur Rahaman Molla,Gokarna Sharma
Distributed Computing and Intelligent Technology Book PDF

Author : Stéphane Devismes,Partha Sarathi Mandal,V. Vijaya Saradhi,Bhanu Prasad,Anisur Rahaman Molla,Gokarna Sharma
Publisher : Springer Nature
Page : 395 pages
File Size : 50,5 Mb
Release : 2024-01-03
Category : Technology & Engineering
ISBN : 9783031505836

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Distributed Computing and Intelligent Technology by Stéphane Devismes,Partha Sarathi Mandal,V. Vijaya Saradhi,Bhanu Prasad,Anisur Rahaman Molla,Gokarna Sharma Pdf

This book constitutes the refereed proceedings of the 20th International Conference on Distributed Computing and Intelligent Technology, ICDCIT 2024, which was held in Bhubaneswar, India, during January 17–20, 2024. The 24 full papers presented in this volume were carefully reviewed and selected from 116 submissions. The papers are organized in the following topical sections: Distributed Computing (DC) and Intelligent Technology (IT). The DC track solicits original research papers contributing to the foundations and applications of distributed computing, whereas the IT track solicits original research papers contributing to the foundations and applications of Intelligent Technology.

Bioinformatics and Human Genomics Research

Diego A. Forero
Bioinformatics and Human Genomics Research Book PDF

Author : Diego A. Forero
Publisher : CRC Press
Page : 509 pages
File Size : 52,9 Mb
Release : 2021-12-23
Category : Science
ISBN : 9781000405682

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Bioinformatics and Human Genomics Research by Diego A. Forero Pdf

Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

Understanding Coronavirus

Raul Rabadan
Understanding Coronavirus Book PDF

Author : Raul Rabadan
Publisher : Cambridge University Press
Page : 167 pages
File Size : 48,7 Mb
Release : 2021-10-14
Category : Medical
ISBN : 9781316514863

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Understanding Coronavirus by Raul Rabadan Pdf

A concise and accessible guide to the coronavirus/COVID-19, fully updated with information on variants, treatment options and vaccines.

Computational Chemogenomics

Edgar Jacoby
Computational Chemogenomics Book PDF

Author : Edgar Jacoby
Publisher : CRC Press
Page : 264 pages
File Size : 54,8 Mb
Release : 2013-12-03
Category : Medical
ISBN : 9789814411400

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Computational Chemogenomics by Edgar Jacoby Pdf

This book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines.

Data Analysis in Molecular Biology and Evolution

Xuhua Xia
Data Analysis in Molecular Biology and Evolution Book PDF

Author : Xuhua Xia
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 49,7 Mb
Release : 2007-05-08
Category : Science
ISBN : 9780306468933

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Data Analysis in Molecular Biology and Evolution by Xuhua Xia Pdf

Data Analysis in Molecular Biology and Evolution introduces biologists to DAMBE, a proprietary, user-friendly computer program for molecular data analysis. The unique combination of this book and software will allow biologists not only to understand the rationale behind a variety of computational tools in molecular biology and evolution, but also to gain instant access to these tools for use in their laboratories. Data Analysis in Molecular Biology and Evolution serves as an excellent resource for advanced level undergraduates or graduates as well as for professionals working in the field.

Topological Analysis

Gordon Thomas Whyburn
Topological Analysis Book PDF

Author : Gordon Thomas Whyburn
Publisher : Princeton University Press
Page : 138 pages
File Size : 42,6 Mb
Release : 2015-12-08
Category : Mathematics
ISBN : 9781400879335

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Topological Analysis by Gordon Thomas Whyburn Pdf

Topological analysis consists of those basic theorems of analysis which are essentially topological in character, developed and proved entirely by topological and pseudotopological methods. The objective of this volume is the promotion, encouragement, and stimulation of the interaction between topology and analysis-to the benefit of both. Originally published in 1964. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Biophotonics and Coherent Systems in Biology

L.V. Beloussov,V.L. Voeikov,V.S. Martynyuk
Biophotonics and Coherent Systems in Biology Book PDF

Author : L.V. Beloussov,V.L. Voeikov,V.S. Martynyuk
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 44,5 Mb
Release : 2007-01-03
Category : Science
ISBN : 9780387284170

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Biophotonics and Coherent Systems in Biology by L.V. Beloussov,V.L. Voeikov,V.S. Martynyuk Pdf

This book is an account of the original papers presented by the participants of the 3rd Alexander Gurwitsch Conference on the Biophotonics and Coherent Systems in Biology, Biophysics and Biotechnology which took place in Tauric University (Crimea, Ukraine) September 27 – October 1, 2004. It features an introduction by Dr. Fritz-Albert Popp (International Institute for Biophysics), leading pioneer of biophotons.

Sequence — Evolution — Function

Eugene V. Koonin,Michael Galperin
Sequence Evolution Function Book PDF

Author : Eugene V. Koonin,Michael Galperin
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 51,8 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781475737837

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Sequence — Evolution — Function by Eugene V. Koonin,Michael Galperin Pdf

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Geometric and Topological Inference

Jean-Daniel Boissonnat,Frédéric Chazal,Mariette Yvinec
Geometric and Topological Inference Book PDF

Author : Jean-Daniel Boissonnat,Frédéric Chazal,Mariette Yvinec
Publisher : Cambridge University Press
Page : 247 pages
File Size : 40,8 Mb
Release : 2018-09-27
Category : Computers
ISBN : 9781108419390

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Geometric and Topological Inference by Jean-Daniel Boissonnat,Frédéric Chazal,Mariette Yvinec Pdf

A rigorous introduction to geometric and topological inference, for anyone interested in a geometric approach to data science.

Statistical Theory and Methods for Evolutionary Genomics

Xun Gu
Statistical Theory and Methods for Evolutionary Genomics Book PDF

Author : Xun Gu
Publisher : OUP Oxford
Page : 272 pages
File Size : 43,5 Mb
Release : 2010-11-04
Category : Science
ISBN : 9780199213269

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Statistical Theory and Methods for Evolutionary Genomics by Xun Gu Pdf

Summarises the statistical framework of evolutionary genomics, and illustrates how statistical modelling and testing can enhance our understanding of functional genomic evolution.

Frontiers in Computational and Systems Biology

Jianfeng Feng,Wenjiang Fu,Fengzhu Sun
Frontiers in Computational and Systems Biology Book PDF

Author : Jianfeng Feng,Wenjiang Fu,Fengzhu Sun
Publisher : Springer Science & Business Media
Page : 24 pages
File Size : 49,7 Mb
Release : 2010-06-14
Category : Science
ISBN : 9781849961967

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Frontiers in Computational and Systems Biology by Jianfeng Feng,Wenjiang Fu,Fengzhu Sun Pdf

Biological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.