Towards Offline Pet Monitoring At A Cyclotron Based Proton Therapy Facility

Author : Matthias Würl
Publisher : Springer
Page : 86 pages
File Size : 40,5 Mb
Release : 2016-05-30
Category : Science
ISBN : 9783658131685

Get Book

Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility by Matthias Würl Pdf

Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields.

Author : Fei Ye,Chao Sun,Yi Xie,Lu Cai,Bing Wang
Publisher : Frontiers Media SA
Page : 146 pages
File Size : 41,6 Mb
Release : 2022-08-25
Category : Medical
ISBN : 9782889768417

Get Book

Medical Application and Radiobiology Research of Particle Radiation by Fei Ye,Chao Sun,Yi Xie,Lu Cai,Bing Wang Pdf

Author : Harald Paganetti
Publisher : CRC Press
Page : 772 pages
File Size : 43,6 Mb
Release : 2018-11-19
Category : Science
ISBN : 9781351855754

Get Book

Proton Therapy Physics, Second Edition by Harald Paganetti Pdf

Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective

Author : Harald Paganetti
Publisher : CRC Press
Page : 691 pages
File Size : 44,5 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781439836453

Get Book

Proton Therapy Physics by Harald Paganetti Pdf

Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Author : Olaf Dössel,Wolfgang C. Schlegel
Publisher : Springer Science & Business Media
Page : 1112 pages
File Size : 49,9 Mb
Release : 2010-01-01
Category : Technology & Engineering
ISBN : 9783642034749

Get Book

World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany by Olaf Dössel,Wolfgang C. Schlegel Pdf

Present Your Research to the World! The World Congress 2009 on Medical Physics and Biomedical Engineering – the triennial scientific meeting of the IUPESM - is the world’s leading forum for presenting the results of current scientific work in health-related physics and technologies to an international audience. With more than 2,800 presentations it will be the biggest conference in the fields of Medical Physics and Biomedical Engineering in 2009! Medical physics, biomedical engineering and bioengineering have been driving forces of innovation and progress in medicine and healthcare over the past two decades. As new key technologies arise with significant potential to open new options in diagnostics and therapeutics, it is a multidisciplinary task to evaluate their benefit for medicine and healthcare with respect to the quality of performance and therapeutic output. Covering key aspects such as information and communication technologies, micro- and nanosystems, optics and biotechnology, the congress will serve as an inter- and multidisciplinary platform that brings together people from basic research, R&D, industry and medical application to discuss these issues. As a major event for science, medicine and technology the congress provides a comprehensive overview and in–depth, first-hand information on new developments, advanced technologies and current and future applications. With this Final Program we would like to give you an overview of the dimension of the congress and invite you to join us in Munich! Olaf Dössel Congress President Wolfgang C.

Author : José-Enrique García-Ramos,Clara E. Alonso,María Victoria Andrés,Francisco Pérez-Bernal
Publisher : Springer
Page : 234 pages
File Size : 41,9 Mb
Release : 2016-05-17
Category : Science
ISBN : 9783319211916

Get Book

Basic Concepts in Nuclear Physics: Theory, Experiments and Applications by José-Enrique García-Ramos,Clara E. Alonso,María Victoria Andrés,Francisco Pérez-Bernal Pdf

This volume covers invited papers presented during the La Rábida 2015 International Scientific Meeting on Nuclear Physics, which can be considered heir of a well known series of triennial international summer schools on Nuclear Physics organized from 1982 till 2003 by the Basic Nuclear Physics group in the University of Sevilla. The La Rábida 2015 meeting offered to graduate students and young researchers a broad view of the field of Nuclear Physics. The first invited speaker presented the state-of-the-art of Relativistic Mean Field calculations. The second set of notes covers selected topics in gamma ray spectroscopy with exotic nuclei. The third speaker presented an introduction to the subject of severe accidents in nuclear power plants. In the fourth set of notes, the author illustrated how to use laser spectroscopy to determine very important observables of atomic nuclei. The fifth speaker devoted its notes to explain several aspects of neutrino physics. Finally, the sixth speaker presented an overview of nuclear medicine and radiodiagnostic. In addition to this, the inclusion of the posters and seminars presented by the students gives a fresh and ample perspective on the many different problems of interest nowadays for the Nuclear Physics community.

Author : Marco Durante,Vincenzo Patera,Yolanda Prezado
Publisher : Frontiers Media SA
Page : 728 pages
File Size : 45,5 Mb
Release : 2021-07-14
Category : Medical
ISBN : 9782889710393

Get Book

Applied Nuclear Physics at Accelerators by Marco Durante,Vincenzo Patera,Yolanda Prezado Pdf

Author : Marco Durante,Francis A. Cucinotta,Jay S. Loeffler
Publisher : Frontiers Media SA
Page : 650 pages
File Size : 54,9 Mb
Release : 2018-01-31
Category : Electronic
ISBN : 9782889453917

Get Book

Charged Particles in Oncology by Marco Durante,Francis A. Cucinotta,Jay S. Loeffler Pdf

High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.

Author : Edward C. Halperin,David E. Wazer,Carlos A. Perez,Luther W. Brady
Publisher : Lippincott Williams & Wilkins
Page : 2448 pages
File Size : 40,5 Mb
Release : 2018-09-06
Category : Medical
ISBN : 9781496386816

Get Book

Perez & Brady's Principles and Practice of Radiation Oncology by Edward C. Halperin,David E. Wazer,Carlos A. Perez,Luther W. Brady Pdf

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. For more than 30 years, Perez and Brady's Principles and Practice of Radiation Oncology has been the must-have standard reference for radiation oncologists and radiation oncology residents who need a comprehensive text covering both the biological and physical science aspects of this complex field as well as disease site-specific information on the integrated, multidisciplinary management of patients with cancer. The book has established itself as the discipline’s "text-of-record," belonging on the shelf of all of those working in the field. The Seventh Edition continues this tradition of excellence with extensive updates throughout, many new chapters, and more than 1,400 full-color illustrations that highlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy.

Author : Adam P. Dicker, MD, PhD,Eric C. Ford, PhD,Tim R. Williams, MD
Publisher : Springer Publishing Company
Page : 352 pages
File Size : 41,8 Mb
Release : 2016-08-17
Category : Medical
ISBN : 9781617052460

Get Book

Quality and Safety in Radiation Oncology by Adam P. Dicker, MD, PhD,Eric C. Ford, PhD,Tim R. Williams, MD Pdf

Quality and Safety in Radiation Oncology is the first book to provide an authoritative and evidence-based guide to the understanding and implementation of quality and safety procedures in radiation oncology practice. Alongside the rapid growth of technology and radiotherapy treatment options for cancer in recent years, quality and safety standards are not only of the utmost importance but best practices ensuring quality and safety are crucial aspect of modern radiation oncology training. A detailed exploration and review of these standards is a necessary part of radiation oncologist’s professional competency, both in the clinical setting and at the study table while preparing for board review and MOC exams. Chapter topics range from fundamental concepts of value and quality to commissioning technology and the use of metrics. They include perspectives on quality and safety from the patient, third-party payers, as well as from the federal government. Other chapters cover prospective testing of quality, training and education, error identification and analysis, incidence reporting, as well as special technology and procedures, including MRI-guided radiation therapy, proton therapy and stereotactic body radiation therapy (SBRT), quality and safety procedures in resource-limited environments, and more. State-of-the-art quality assurance procedures and safety guidelines are the backbone of this unique and essential volume. Physicians, medical physicists, dosimetrists, radiotherapists, hospital administrators, and other healthcare professionals will find this resource an invaluable compendium of best practices in radiation oncology. Key Features: Case examples illustrate best practices and pitfalls Several dozen graphs, tables and figures help quantify the discussion of quality and safety throughout the text Section II covers all aspects of quality assurance procedures for the physicist

Author : Lanchun Lu,Heng Li,Lin Kong,Marco Durante,Oliver Jäkel
Publisher : Frontiers Media SA
Page : 163 pages
File Size : 51,5 Mb
Release : 2023-04-28
Category : Medical
ISBN : 9782832522097

Get Book

Image-guided particle therapy by Lanchun Lu,Heng Li,Lin Kong,Marco Durante,Oliver Jäkel Pdf

Author : Hans Geinitz,Mack Roach III,Nicholas van As
Publisher : Springer
Page : 288 pages
File Size : 52,5 Mb
Release : 2014-11-18
Category : Medical
ISBN : 9783642370991

Get Book

Radiotherapy in Prostate Cancer by Hans Geinitz,Mack Roach III,Nicholas van As Pdf

Today, the arsenal of “high-precision” or “targeted” radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.

Author : Frank Verhaegen,Joao Seco
Publisher : CRC Press
Page : 291 pages
File Size : 41,8 Mb
Release : 2021-11-29
Category : Medical
ISBN : 9781000455557

Get Book

Monte Carlo Techniques in Radiation Therapy by Frank Verhaegen,Joao Seco Pdf

Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.

Author : Laura Harkness-Brennan
Publisher : Morgan & Claypool Publishers
Page : 95 pages
File Size : 54,7 Mb
Release : 2018-06-27
Category : Science
ISBN : 9781643270340

Get Book

An Introduction to the Physics of Nuclear Medicine by Laura Harkness-Brennan Pdf

The complexity and vulnerability of the human body has driven the development of a diverse range of diagnostic and therapeutic techniques in modern medicine. The Nuclear Medicine procedures of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and Radionuclide Therapy are well-established in clinical practice and are founded upon the principles of radiation physics. This book will offer an insight into the physics of nuclear medicine by explaining the principles of radioactivity, how radionuclides are produced and administered as radiopharmaceuticals to the body and how radiation can be detected and used to produce images for diagnosis. The treatment of diseases such as thyroid cancer, hyperthyroidism and lymphoma by radionuclide therapy will also be explored.

Author : Anonim
Publisher : Unknown
Page : 930 pages
File Size : 45,8 Mb
Release : 1990
Category : Biomedical engineering
ISBN : UIUC:30112007796540

Get Book

The Engineering Index Bioengineering and Biotechnology Abstracts by Anonim Pdf