Transport Abc

Author : Adam Low,Jonathan Hulme
Publisher : John Wiley & Sons
Page : 224 pages
File Size : 55,8 Mb
Release : 2014-10-24
Category : Medical
ISBN : 9781118719749

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ABC of Transfer and Retrieval Medicine by Adam Low,Jonathan Hulme Pdf

ABC of Transfer and Retrieval Medicine provides the key information required to help health care professionals involved in the movement of critically ill patients to do so safely, correctly and with confidence. Beginning with the practical and clinical considerations to be taken into account during patient transfer and an overview of transfer equipment, it then addresses pharmacological aspects of patient transfer, the roles and responsibilities of the transfer team, and the requirements of neonatal, paediatric and specialist transfers. Mapped against the syllabus for the Diploma of Retrieval and Transfer Medicine (Royal College of Surgeons of Edinburgh), it has been developed as a core resource for the diploma whilst providing an invaluable resource for any healthcare professional involved in the transfer of critically ill patients including anaesthetists, intensivists, nurses from ICU/ED and paramedics. It also includes frameworks for radiology and arterial blood gas interpretation, guidance on patient triage, transfer checklists and equipment checklists, and a summary of the relevant national guidelines. From a multidisciplinary international author team, this new addition to the ABC series is a useful resource for all health care professionals involved in the transfer of patients. It is relevant to anaesthetists, intensivists, paramedics, critical care and emergency department nursing staff who are required to take part in intra and inter hospital transfers.

Author : I Barry Holland,Susan P. C. Cole,Karl Kuchler,Christopher F. Higgins
Publisher : Elsevier
Page : 530 pages
File Size : 50,8 Mb
Release : 2003-01-07
Category : Science
ISBN : 9780080481876

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ABC Proteins by I Barry Holland,Susan P. C. Cole,Karl Kuchler,Christopher F. Higgins Pdf

ABC Proteins is an in-depth, up-to-date analysis of all that is known about the subject to date. It discusses and compares evolution, biology and mechanism of action of all known ABC proteins, including the first structural studies as well as clinical implications. It will be useful to anyone trying to stay abreast of the latest findings. This book is sure to become a classic and will regularly be updated. Phylogeny and Evoloution of ABC Transporters Fundamental Aspects of the Mechanism of Action of ABC Transporters Prokaryote ABC Transporters Non-Mammalian Transporters Multidrug Transporters ABC Transporters, Physiological Roles and Human Disease Full color throughout

Author : Markus Geisler
Publisher : Springer
Page : 333 pages
File Size : 50,8 Mb
Release : 2014-09-06
Category : Science
ISBN : 9783319065113

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Plant ABC Transporters by Markus Geisler Pdf

This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species. ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids. The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.

Author : Alan Talevi
Publisher : Springer Nature
Page : 1209 pages
File Size : 45,7 Mb
Release : 2022-06-14
Category : Medical
ISBN : 9783030848606

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The ADME Encyclopedia by Alan Talevi Pdf

The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties

Author : Martin G. Klotz,Donald A. Bryant,Jim K. Fredrickson,William P. Inskeep,Michael Kühl
Publisher : Frontiers Media SA
Page : 264 pages
File Size : 48,8 Mb
Release : 2016-04-11
Category : Electronic book
ISBN : 9782889197934

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Systems biology and ecology of microbial mat communities by Martin G. Klotz,Donald A. Bryant,Jim K. Fredrickson,William P. Inskeep,Michael Kühl Pdf

Microbial mat communities consist of dense populations of microorganisms embedded in exopolymers and/or biomineralized solid phases, and are often found in mm-cm thick assemblages, which can be stratified due to environmental gradients such as light, oxygen or sulfide. Microbial mat communities are commonly observed under extreme environmental conditions, deriving energy primarily from light and/or reduced chemicals to drive autotrophic fixation of carbon dioxide. Microbial mat ecosystems are regarded as living analogues of primordial systems on Earth, and they often form perennial structures with conspicuous stratifications of microbial populations that can be studied in situ under stable conditions for many years. Consequently, microbial mat communities are ideal natural laboratories and represent excellent model systems for studying microbial community structure and function, microbial dynamics and interactions, and discovery of new microorganisms with novel metabolic pathways potentially useful in future industrial and/or medical applications. Due to their relative simplicity and organization, microbial mat communities are often excellent testing grounds for new technologies in microbiology including micro-sensor analysis, stable isotope methodology and modern genomics. Integrative studies of microbial mat communities that combine modern biogeochemical and molecular biological methods with traditional microbiology, macro-ecological approaches, and community network modeling will provide new and detailed insights regarding the systems biology of microbial mats and the complex interplay among individual populations and their physicochemical environment. These processes ultimately control the biogeochemical cycling of energy and/or nutrients in microbial systems. Similarities in microbial community function across different types of communities from highly disparate environments may provide a deeper basis for understanding microbial community dynamics and the ecological role of specific microbial populations. Approaches and concepts developed in highly-constrained, relatively stable natural communities may also provide insights useful for studying and understanding more complex microbial communities.

Author : Ahcène Boumendjel,Jean Boutonnat,Jacques Robert
Publisher : John Wiley & Sons
Page : 475 pages
File Size : 46,6 Mb
Release : 2009-06-17
Category : Medical
ISBN : 9780470495124

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ABC Transporters and Multidrug Resistance by Ahcène Boumendjel,Jean Boutonnat,Jacques Robert Pdf

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.

Author : Wil Konings,Wilhelmus Nicolaas Konings,O.P. Kuipers,J.H.J. Huis in 't Veld
Publisher : Springer Science & Business Media
Page : 432 pages
File Size : 43,5 Mb
Release : 1999-09-30
Category : Medical
ISBN : 0792359534

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Lactic Acid Bacteria: Genetics, Metabolism and Applications by Wil Konings,Wilhelmus Nicolaas Konings,O.P. Kuipers,J.H.J. Huis in 't Veld Pdf

Proceedings of the Sixth Symposium on Lactic Acid Bacteria: Genetics, Metabolism and Applications 19-23 September 1999, Veldhoven, The Netherlands

Author : Jacquelyn L. Banasik
Publisher : Elsevier Health Sciences
Page : 1200 pages
File Size : 47,7 Mb
Release : 2018-01-17
Category : Electronic
ISBN : 9780323510424

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Pathophysiology - E-Book by Jacquelyn L. Banasik Pdf

Develop a strong understanding of pathophysiology. Pathophysiology, 6th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. Each section focuses on the major alterations in the homeostasis of the body systems in order to provide you with a unifying framework. Current scientific findings and relevant global research are integrated throughout the book, with chapters organized by body system, beginning with an illustrated review of anatomy and normal physiology. Each chapter includes a discussion on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading educators, this text simplifies a rigorous subject with practical learning resources, an emphasis on critical thinking, and coverage of the latest scientific findings and relevant research. Plus, more than 1,000 updated, full color illustrations and photos throughout, give you a chance to visualize disease and disease processes and gain a clearer understanding of the material. Easy-to-read style is simplified by input from readability experts, and includes many tables, boxes, and figures to highlight key content. Student-friendly learning resources in the text include chapter outlines, bolded key terms, key questions, Key Points boxes, and chapter summaries. Pediatric and Geriatric Considerations boxes include brief analyses of age-related changes associated with specific body systems. A comprehensive glossary defines terms and includes audio pronunciations on the Evolve companion website. NEW! Global Health Care boxes inform you about global healthcare concerns such as HIV/AIDS, Ebola, Tropical Diseases and more. Includes prevalence, mechanism of disease and transmission. NEW! Over 1,000 illustrations help clarify complex pathophysiological concepts and make the book visually appealing NEW! Thorough chapter updates include the latest information on new treatment advances, 100 new figures for improved clarity, and much more throughout the text.

Author : Christine M.F. Vos,Kemal Kazan
Publisher : Springer
Page : 410 pages
File Size : 42,7 Mb
Release : 2016-11-17
Category : Science
ISBN : 9783319423197

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Belowground Defence Strategies in Plants by Christine M.F. Vos,Kemal Kazan Pdf

This book summarizes our current knowledge on belowground defence strategies in plants by world-class scientists actively working in the area. The volume includes chapters covering belowground defence to main soil pathogens such as Fusarium, Rhizoctonia, Verticillium, Phytophthora, Pythium and Plasmodiophora, as well as to migratory and sedentary plant parasitic nematodes. In addition, the role of root exudates in belowground plant defence will be highlighted, as well as the crucial roles of pathogen effectors in overcoming root defences. Finally, accumulating evidence on how plants can differentiate beneficial soil microbes from the pathogenic ones will be covered as well. Better understanding of belowground defences can lead to the development of environmentally friendly plant protection strategies effective against soil-borne pathogens which cause substantial damage on many crop plants all over the world. The book will be a useful reference for plant pathologists, agronomists, plant molecular biologists as well as students working on these and related areas.

Author : Byung Hong Kim,Geoffrey Michael Gadd
Publisher : Cambridge University Press
Page : 509 pages
File Size : 44,5 Mb
Release : 2019-05-16
Category : Medical
ISBN : 9781107171732

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Prokaryotic Metabolism and Physiology by Byung Hong Kim,Geoffrey Michael Gadd Pdf

Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Author : Kundan Kumar,Sudhakar Srivastava
Publisher : Springer Nature
Page : 455 pages
File Size : 47,8 Mb
Release : 2022-10-29
Category : Science
ISBN : 9789811961038

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Plant Metal and Metalloid Transporters by Kundan Kumar,Sudhakar Srivastava Pdf

This edited book stands as a one place knowledge hub for plant metal(loid) transporters. The book comprehensively covers holistic aspect of metal(loid) transporters involved in uptake and translocation of essential as well as toxic metal(loid)s. Essential and beneficial metal(loid)s are required in every biological process for normal plant growth and development, however in excess they are toxic. There are toxic metal(loid)s also whose accumulation in plants interferes with normal cellular functioning and hampers growth of plants. Hence, metal(loid) uptake and accumulation in plants is a highly regulated phenomenon involving the role of several transporters, enzymes, metabolites, transcription factors and post translational modifications. The book contains chapters from the experts and the contents of the book are presented in simple language and represented through beautiful and scientifically informative figures and tables. This book is of interest to teachers, researchers, doctoral and graduate students working in the area of plant physiology, environmental biotechnology, plant biotechnology metal(loid) stress, phytoremediation and crop biofortification.

Author : United States. Federal Energy Regulatory Commission
Publisher : Unknown
Page : 1490 pages
File Size : 40,7 Mb
Release : 1981
Category : Energy conservation
ISBN : NWU:35559001985401

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Federal Energy Regulatory Commission Reports by United States. Federal Energy Regulatory Commission Pdf

Author : Pawan K. Jaiwal,Rana P. Singh,Om Parkash Dhankher
Publisher : CABI
Page : 391 pages
File Size : 42,6 Mb
Release : 2008
Category : Science
ISBN : 9781845934026

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Plant Membrane and Vacuolar Transporters by Pawan K. Jaiwal,Rana P. Singh,Om Parkash Dhankher Pdf

This book contains 14 chapters that evaluate the current knowledge, state of art and future prospects of plant membrane and vacuolar transporters in relation to plant productivity and quality improvement. The role of transporters, the mechanisms of uptake, accumulation or transport of potassium, calcium, nitrate, ammonium, sulfate, phosphate, iron, manganese, silicon, heavy metals, sugars, polyols, amino acids and secondary metabolites, the proteomic analysis of vacuolar membrane, and the elemental biofortification of crop plants are emphasized. The book is intended for scientists, researchers, students, planners and industrialists working in the area of biotechnology, plant agriculture, agronomy, horticulture, plant physiology, molecular biology, nutritional biology, plant sciences and environmental sciences.

Author : Josep M. Gasol,David L. Kirchman
Publisher : John Wiley & Sons
Page : 528 pages
File Size : 48,6 Mb
Release : 2018-01-31
Category : Science
ISBN : 9781119107194

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Microbial Ecology of the Oceans by Josep M. Gasol,David L. Kirchman Pdf

The newly revised and updated third edition of the bestselling book on microbial ecology in the oceans The third edition of Microbial Ecology of the Oceans features new topics, as well as different approaches to subjects dealt with in previous editions. The book starts out with a general introduction to the changes in the field, as well as looking at the prospects for the coming years. Chapters cover ecology, diversity, and function of microbes, and of microbial genes in the ocean. The biology and ecology of some model organisms, and how we can model the whole of the marine microbes, are dealt with, and some of the trophic roles that have changed in the last years are discussed. Finally, the role of microbes in the oceanic P cycle are presented. Microbial Ecology of the Oceans, Third Edition offers chapters on The Evolution of Microbial Ecology of the Ocean; Marine Microbial Diversity as Seen by High Throughput Sequencing; Ecological Significance of Microbial Trophic Mixing in the Oligotrophic Ocean; Metatranscritomics and Metaproteomics; Advances in Microbial Ecology from Model Marine Bacteria; Marine Microbes and Nonliving Organic Matter; Microbial Ecology and Biogeochemistry of Oxygen-Deficient Water Columns; The Ocean’s Microscale; Ecological Genomics of Marine Viruses; Microbial Physiological Ecology of The Marine Phosphorus Cycle; Phytoplankton Functional Types; and more. A new and updated edition of a key book in aquatic microbial ecology Includes widely used methodological approaches Fully describes the structure of the microbial ecosystem, discussing in particular the sources of carbon for microbial growth Offers theoretical interpretations of subtropical plankton biogeography Microbial Ecology of the Oceans is an ideal text for advanced undergraduates, beginning graduate students, and colleagues from other fields wishing to learn about microbes and the processes they mediate in marine systems.

Author : Rouf Ahmad Bhat,Gowhar Hamid Dar,Fernanda Maria Policarpo Tonelli,Saima Hamid
Publisher : John Wiley & Sons
Page : 420 pages
File Size : 44,7 Mb
Release : 2023-09-26
Category : Science
ISBN : 9781119989301

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Aquatic Contamination by Rouf Ahmad Bhat,Gowhar Hamid Dar,Fernanda Maria Policarpo Tonelli,Saima Hamid Pdf

Aquatic Contamination Authoritative resource presenting techniques and technologies to sustainably neutralize environmental contamination in aquatic plants, microorganisms, and more Two thirds of the Earth is covered with aquatic habitats that play a key role in stabilizing the global environment and providing a wide variety of services to increasing human needs. Nevertheless, anthropogenic activities are rapidly destroying the quality of both fresh and marine waters globally, due to excessive use of chemicals, fertilizers and pollution from suburban and industrial areas eventually making their way into the aquatic world. Aquatic Contamination: Tolerance and Bioremediation presents the broader spectrum of biological applicability of microbes with better understanding of cellular mechanisms for remediation of aquatic contaminants. The book also focuses on practices involved in molecular and genetic approaches, necessary to achieve targets of bioremediation and phytoremediation to solve global water contamination problems. Such approaches pave the way for the utilization of biological assets to design new, efficient, and environmentally sound remediation strategies by inculcating genomic techniques at cellular and molecular levels with model assessment. Aquatic Contamination provides a comprehensive background for readers interested in all perspectives of the contamination of aquatic environs. It covers various research aspects which are being carried out globally to understand simulation models in the assessment of xenobiotics, role of genomics, transgenic plants, and microbial enzymes for degradation and removal of toxic substances in aquatic environs. Key features include: Extensive coverage of interactions between plants, metals and microbes including the influence of biotic and abiotic factors Comprehensive discussion of the details of molecular mechanisms from assimilation to detoxification levels Exploration of the enzymatic approaches of potential plants acting as hyper-accumulators for contaminants in aquatic environs Details of sustainable tools such as transgenic plants for the manipulation of important functional microbial genes to achieve higher certainty of bioremediation Details of advances in tools and models like micro-arrays and simulation models for the complete assessment of xenobiotic compounds from cellular to degradation hierarchies Aquatic Contamination: Tolerance and Bioremediation will be substantially helpful to environmentalists, microbiologists, biotechnologists and scientists, providing essential information on various modern technologies for the remediation of contaminants in aquatic ecosystems.