Tuberculosis Leprosy And Mycobacterial Diseases Of Man And Animals

Author : Harshini Mukundan,Mark A. Chambers,W. Ray Waters,Michelle H Larsen
Publisher : Unknown
Page : 561 pages
File Size : 55,9 Mb
Release : 2015
Category : Mycobacterial diseases
ISBN : 1789244684

Get Book

Tuberculosis, Leprosy and Other Mycobacterial Diseases of Man and Animals by Harshini Mukundan,Mark A. Chambers,W. Ray Waters,Michelle H Larsen Pdf

Mycobacteria have been associated with human and animal disease for millennia. This book is founded on a principle of cross-disciplinary inclusion and the belief that by bringing together all members of the mycobacterial research community we could achieve a better understanding of mycobacteria and the diseases caused by them, and thus contribute to knowledge and the development of products to improve global health. It is based on a series of workshops, held since 2007, which have fostered an interdisciplinary approach and unique collaborations that benefit multiple scientific communities. The sharing of ideas and results across disciplines has allowed for enhancement of research in Mycobacterium tuberculosis, M. bovis, M. leprae and other non-tuberculous mycobacteria. Most of all, it has increased the knowledge of researchers who are developing vaccines, diagnostics and drugs to prevent, diagnose and treat some of the oldest pathogens of man. By bringing together a multidisciplinary team of leading scientists studying mycobacterial infections in humans and animals, the workshops have created a venue for sharing knowledge about the spectrum of mycobacterial diseases, exploring host-pathogen variability, and understanding what the commonalities and differences in disease presentation and host specificity teach us. The book is divided into six parts that discuss tuberculosis in humans; tuberculosis in domesticated and companion animal species; mycobacterial infections in zoo species; tuberculosis in wildlife; in vivo laboratory models of tuberculosis; and other mycobacterial diseases. This book serves to share the lessons learned from these workshops not only within the mycobacterial community, but also to a wider audience, as this approach may benefit other fields of research.

Author : Harshini Mukundan,Mark Chambers,Ray Waters,Michelle Larsen
Publisher : CABI
Page : 587 pages
File Size : 42,5 Mb
Release : 2015-09-28
Category : Medical
ISBN : 9781780643960

Get Book

Tuberculosis, Leprosy and Mycobacterial Diseases of Man and Animals by Harshini Mukundan,Mark Chambers,Ray Waters,Michelle Larsen Pdf

Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.

Author : American Association for the Advancement of Science. Section on Medical Sciences
Publisher : Unknown
Page : 144 pages
File Size : 51,8 Mb
Release : 1938
Category : Medical
ISBN : WISC:89031266125

Get Book

Tuberculosis and Leprosy, the Mycobacterial Diseases by American Association for the Advancement of Science. Section on Medical Sciences Pdf

Author : King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha
Publisher : World Bank Publications
Page : 506 pages
File Size : 49,5 Mb
Release : 2017-11-06
Category : Medical
ISBN : 9781464805257

Get Book

Disease Control Priorities, Third Edition (Volume 6) by King K. Holmes,Stefano Bertozzi,Barry R. Bloom,Prabhat Jha Pdf

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Author : Gerd Pluschke,Katharina Röltgen
Publisher : Springer
Page : 287 pages
File Size : 43,6 Mb
Release : 2019-04-29
Category : Medical
ISBN : 9783030111144

Get Book

Buruli Ulcer by Gerd Pluschke,Katharina Röltgen Pdf

A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

Author : Rudolph J. Anderson,Joseph D. Aronson
Publisher : Unknown
Page : 134 pages
File Size : 42,5 Mb
Release : 2013-08
Category : Electronic
ISBN : 1258795043

Get Book

Tuberculosis and Leprosy by Rudolph J. Anderson,Joseph D. Aronson Pdf

Additional Contributors Include Sam H. Black, H. J. Corper, Arthur B. Crawford And Others.

Author : Domenico Bonamonte,Gianni Angelini
Publisher : Springer
Page : 398 pages
File Size : 55,7 Mb
Release : 2017-09-04
Category : Medical
ISBN : 9783319485386

Get Book

Mycobacterial Skin Infections by Domenico Bonamonte,Gianni Angelini Pdf

This well-illustrated book is a comprehensive guide to the cutaneous clinical presentations of mycobacterial infections. The Mycobacterium genus includes over 170 species, nontuberculous mycobacteria (NTM) having been added to the obligate human pathogens such as M. tuberculosis and M. leprae. NTM are widely distributed in the environment with high isolation rates worldwide; the skin is a major target with variable clinical manifestations. A current resurgence in tuberculosis is aggravated by the synergy with human immunodeficiency virus, the breakdown of health care systems, and the rise in multidrug-resistant disease, as the incidence of leprosy remains stable, at around 250,000 new cases annually, regardless of effective antibiotic therapy. Presentations of various cutaneous infections caused by mycobacteria may be overlooked by clinicians owing the lack of familiarity with tuberculosis, leprosy, and the related NTM clinical features. This handy guide will help the dermatologist to spot the different clinical manifestations, make a prompt diagnosis, and apply effective treatment.

Author : Asseged B. Dibaba,Nicolaas P. J. Kriek,Charles O. Thoen
Publisher : Springer
Page : 453 pages
File Size : 52,5 Mb
Release : 2019-07-01
Category : Science
ISBN : 9783030186906

Get Book

Tuberculosis in Animals: An African Perspective by Asseged B. Dibaba,Nicolaas P. J. Kriek,Charles O. Thoen Pdf

This book recounts the biology of M. bovis, followed by the status of bovine Tuberculosis (bTB) in African countries, primarily based on zoonotic and epidemiological field reports. Since the accumulation of data is valueless unless it led to practicable control measures, emphasis is put on locally adapted protocols for future control of the disease. In order to systematically evaluate the knowledge base of bTB, Epidemiologic Problem Oriented Approach (EPOA) methodology was used. The methodology is composed of two triads: i) the problem identification/characterization triad, which is mainly descriptive in nature, and ii) the problem management/solution/mitigation triad, which is mainly geared toward problem management/solution (see figure). The first triad comprises three pillars: i) agent ii) host, and iii) environment and the second one: i) therapeutics/treatment, ii) prevention/control, and iii) health maintenance/promotion. The two triads are linked together by the diagnostic procedure linkage. The systematic and detailed studies of the ‘Host-Agent-Environment’ interactions are the building blocks to the understanding of agent transmission pathways and disease spread. These may include data about the disease status of the country, the nature of the disease agent and its hosts, the modes of transmission, the wildlife reservoirs in nature, persistence of infection, and agent survival in animal products and the environment. The problem identification and characterization triad identifies these interactions. Once a problem has been identified and well understood, the next step is to minimize the risk of transmission and spread of a disease. This area, referred to as problem solution/management triad, consists of problem management alternatives that rely upon prevention/control, and health maintenance/promotion of the disease in livestock, wildlife, and humans with the emphasis on resource-poor, developing countries in Africa.

Author : William R. Jacobs, Jr.,Helen McShane,Valerie Mizrahi,Ian M. Orme
Publisher : John Wiley & Sons
Page : 741 pages
File Size : 48,9 Mb
Release : 2020-07-15
Category : Medical
ISBN : 9781555819569

Get Book

Tuberculosis and the Tubercle Bacillus by William R. Jacobs, Jr.,Helen McShane,Valerie Mizrahi,Ian M. Orme Pdf

Can today's innovative practices and molecular tools tame this ancient disease? One third of the world's population is infected with tuberculosis (TB), with about 10 million new cases annually. To combat TB and its agent, Mycobacterium tuberculosis, the World Health Organization launched The End TB Strategy, which aims to slash the suffering and cost of TB by 2035. This makes the second edition of Tuberculosis and the Tubercle Bacillus, edited by Jacobs, McShane, Mizrahi, and Orme, an extremely valuable resource for scientists and clinicians. The editors have gathered their colleagues from around the world to present the latest on the molecular biology of M. tuberculosis and related species, the host-pathogen interactions that enable invasion, and the host's immune response to M. tuberculosis infection. The basic, clinical, and translational research presented in this book supports the goals of WHO's End TB Strategy by driving toward the development of effective vaccines, rapid molecular diagnostics, and anti-TB drugs. Creating an effective tuberculosis vaccine. Understand the innate and adaptive immune response to M. tuberculosis infection, its study in established animal models, and how this information is being used to develop new vaccines against TB. Formulating new antituberculosis drugs. Learn the challenges and methods for evaluating new drugs in preclinical trials with a focus on drugs that work against "persisters" and those that act on the electron transport complex and ATP synthase of M. tuberculosis. Overcoming the challenges of diagnosing tuberculosis. Review new diagnostic tools that are simple, rapid, affordable, specific, sensitive, and safe, including molecular-based diagnostic methods such as GeneXpert MTB/RIF. Using molecular, genomic, and bioinformatics tools to understand the biology and evolution of Mycobacterium. Explore current research on the molecular mechanisms that M. tuberculosis uses to evade the immune system, enter a state of nonreplicating persistence, and become reactivated. The second edition of Tuberculosis and the Tubercle Bacillus presents the latest research on a microorganism that is exquisitely well adapted to its human host. This pathogen continues to confound scientists, clinicians, and public health specialists, who will all find much valuable information in this comprehensive set of reviews.

Author : David A. Jessup,Robin W. Radcliffe
Publisher : JHU Press
Page : 656 pages
File Size : 45,9 Mb
Release : 2023-08-15
Category : Science
ISBN : 9781421446752

Get Book

Wildlife Disease and Health in Conservation by David A. Jessup,Robin W. Radcliffe Pdf

Provides wildlife professionals with cutting-edge scientific information on the most damaging and newly emerging wildlife diseases. Wildlife diseases and their implications are at the forefront of many sectors of scientific endeavor, especially in the wake of the COVID-19 pandemic. Nearly 60 percent of all human diseases and 75 percent of all emerging infectious diseases are zoonotic. Edited by pioneering wildlife veterinarians David A. Jessup and Robin W. Radcliffe, Wildlife Disease and Health in Conservation explores the origins and impacts of as well as the responses to the most damaging and persistent diseases currently threatening wildlife conservation. Focusing mainly on newer, invasive, and controversial wildlife health challenges, this book also reexamines classic diseases that provide warnings and important lessons for wildlife professionals and policy makers. Each chapter offers cutting-edge scientific information and extensive references to help readers plan for, respond to, and conduct research on these serious health challenges. This book: • Reports crucial findings on newly emerging diseases and how to recognize and manage them • Explores the health of critical but often neglected aquatic ecosystems, including both vertebrate and invertebrate examples • Covers a vast diversity of wildlife health threats, from epizootic bighorn sheep pneumonia and African swine fever to sea star wasting disease, avian influenza, and rabbit hemorrhagic disease • Explains zoonotic dangers to humans, including coronaviruses • Includes information on marine and aquatic species, wild ungulate species, carnivores and omnivores, birds, and more • Provides insight into the social, legal, financial, and political factors that may override or influence conservation priorities in response to biomedical challenges Featuring detailed and attractive field notes–style illustrations by Laura Donohue and essential essays from experts in the field, Wildlife Disease and Health in Conservation combines theory and practice to inform and inspire wildlife health and conservation.

Author : Federico Blanco,Flabio R. Araujo,Jacobus Henri De Waard,Christophe J. Queval
Publisher : Frontiers Media SA
Page : 190 pages
File Size : 52,8 Mb
Release : 2022-07-01
Category : Medical
ISBN : 9782889748914

Get Book

Recent Advances in Bovine Tuberculosis by Federico Blanco,Flabio R. Araujo,Jacobus Henri De Waard,Christophe J. Queval Pdf

Author : Sebastien Gagneux
Publisher : Springer
Page : 314 pages
File Size : 52,5 Mb
Release : 2018-08-31
Category : Science
ISBN : 3319877763

Get Book

Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control by Sebastien Gagneux Pdf

Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a “clone” with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically “relevant”. This view has now changed quite dramatically thanks to the –omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously. Moreover, an increasing number of experimental and epidemiological studies are showing that this genetic diversity also translates into important phenotypic variation. Taken together, these findings have led to a paradigm shift, such that currently phylogenetic diversity among M. tuberculosis clinical strains is being considered in the development of new tools to combat tuberculosis. The purpose of this book is to bring together a series of contributions from some of the most influential groups working on various aspects of M. tuberculosis diversity, and which through their work have contributed to the this paradigm shift. This includes authors focusing on the evolution of M. tuberculosis in relation to other members of the M. tuberculosis complex adapted to animals, the co-evolution between M. tuberculosis and humans, the phenotypic consequences of strains diversity both from an experimental and epidemiological point of view, the ecology and evolution of drug resistant tuberculosis, the diversity and evolution of the BCG vaccine strains, and the use of mathematical modelling to study strain diversity and drug resistance in human tuberculosis. No such book has ever been published, and given the paradigm shift described above, this book will be a valuable resource both for established researchers as well as new scientists, clinicians and public health officials joining the growing field of tuberculosis research.

Author : Mark Chambers,Stephen Gordon,Francisco Olea-Popelka,Paul Barrow
Publisher : CABI
Page : 283 pages
File Size : 54,5 Mb
Release : 2018-04-13
Category : Medical
ISBN : 9781786391520

Get Book

Bovine Tuberculosis by Mark Chambers,Stephen Gordon,Francisco Olea-Popelka,Paul Barrow Pdf

This book is contemporary, topical and global in its approach, and provides an essential, comprehensive treatise on bovine tuberculosis and the bacterium that causes it, Mycobacterium bovis. Bovine tuberculosis remains a major cause of economic loss in cattle industries worldwide, exacerbated in some countries by the presence of a substantial wildlife reservoir. It is a major zoonosis, causing human infection through consumption of unpasteurised milk or by close contact with infected animals. Following a systematic approach, expert international authors cover epidemiology and the global situation; microbial virulence and pathogenesis; host responses to the pathogen; and diagnosis and control of the disease. Aimed at researchers and practising veterinarians, this book is essential for those needing comprehensive information on the pathogen and disease, and offers a summary of key information learned from human tuberculosis research. It will be useful to those studying the infection and for those responsible for controlling the disease.

Author : Anonim
Publisher : Academic Press
Page : 719 pages
File Size : 51,5 Mb
Release : 2013-11-08
Category : Science
ISBN : 9780124159761

Get Book

Microbiology of Waterborne Diseases by Anonim Pdf

The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters

Author : Gbolagade Akeem Lameed
Publisher : BoD – Books on Demand
Page : 102 pages
File Size : 45,6 Mb
Release : 2017-03-22
Category : Technology & Engineering
ISBN : 9789535130253

Get Book

Global Exposition of Wildlife Management by Gbolagade Akeem Lameed Pdf

The book, Global Exposition of Wildlife Management, covers five research topics connected to wildlife management. From conservation and domestication of species from the wild, the socioeconomic importance of wildlife to Tuberculosis within wildlife species as an emerging health threat for both wildlife and humans. Topics presented also discuss bush-meat utilization and its impact on biodiversity conservation, community forestry management and its role in biodiversity conservation, food and feeding ecology, urban forestry, and integrated island management for ecologically sensitive areas. This book also presents wildlife conservation research using a public aquarium as a case study. Each chapter gives special reference to the prevailing problems in wildlife conservation and hopes to provide possible solutions.