Understanding Neuropsychiatric Disorders

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Understanding Neuropsychiatric Disorders

Author : Martha E. Shenton,Bruce I. Turetsky
Publisher : Cambridge University Press
Page : 591 pages
File Size : 54,5 Mb
Release : 2010-12-09
Category : Medical
ISBN : 9781139493697

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Understanding Neuropsychiatric Disorders by Martha E. Shenton,Bruce I. Turetsky Pdf

An informative and comprehensive review from the leading researchers in the field, this book provides a complete one-stop guide to neuroimaging techniques and their application to a wide range of neuropsychiatric disorders. For each disorder or group of disorders, separate chapters review the most up-to-date findings from structural imaging, functional imaging and/or molecular imaging. Each section ends with an overview from a internationally-renowned luminary in the field, addressing the question of 'What do we know and where are we going?' Richly illustrated throughout, each chapter includes a 'summary box', providing readers with explicit take-home messages. This is an essential resource for clinicians, researchers and trainees who want to learn how neuroimaging tools lead to new discoveries about brain and behaviour associations in neuropsychiatric disorders.

Cannabinoids and Neuropsychiatric Disorders

Author : Eric Murillo-Rodriguez,S. R. Pandi-Perumal,Jaime M. Monti
Publisher : Springer Nature
Page : 163 pages
File Size : 47,6 Mb
Release : 2020-12-17
Category : Science
ISBN : 9783030573690

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Cannabinoids and Neuropsychiatric Disorders by Eric Murillo-Rodriguez,S. R. Pandi-Perumal,Jaime M. Monti Pdf

This volume highlights the recent advances in the understanding of the endocannabinoid system and the likely benefit from the therapeutic effects of cannabinoid treatment in a variety of health issues. Archeological evidence has shown that Cannabis has a long history of use for multiple purposes, including the treatment of medical conditions. The primary active constituent of the hemp plant Cannabis sativa, delta 9-tetrahydrocannabinol (Δ9-THC), causes euphoria, enhancement of sensory perception, tachycardia, antinociception, difficulties in concentration and impairment of memory, among other effects. Despite these undesirable effects, signaling is mostly inhibitory and suggests a putative role for cannabinoids as therapeutic agents by managing several diseases where inhibition of neurotransmitter release would be beneficial. The themes of this book have been edited and written by world-leaders in the field, The contents of the volume aims at readers from a range of academic and professional disciplines, such as biomedicine, several areas of biology, neurology, clinical medicine and pharmacy.

Brain Network Dysfunction in Neuropsychiatric Illness

Author : Vaibhav A. Diwadkar,Simon B. Eickhoff
Publisher : Springer Nature
Page : 492 pages
File Size : 54,9 Mb
Release : 2021-05-11
Category : Medical
ISBN : 9783030597979

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Brain Network Dysfunction in Neuropsychiatric Illness by Vaibhav A. Diwadkar,Simon B. Eickhoff Pdf

Brain network function and dysfunction is the dominant model for understanding how the brain gives rise to normal and abnormal behavior. Moreover, neuropsychiatric illnesses continue to resist attempts to reveal an understanding of their bases. Thus, this timely volume provides a synthesis of the uses of multiple analytic methods as they are applied to neuroimaging data, to seek understanding of the neurobiological bases of psychiatric illnesses, understanding that can subsequently aid in their management and treatment. A principle focus is on the analyses and application of methods to functional magnetic resonance imaging (fMRI) data. fMRI remains the most widely used neuroimaging technique for estimating brain network function, and several of the methods covered can estimate brain network dysfunction in resting and task-active states. Additional chapters provide details on how these methods are (and can be) applied in the understanding of several neuropsychiatric disorders, including schizophrenia, mood disorders, autism, borderline personality disorder, and attention deficit hyperactivity disorder (ADHD). A final complement of chapters provides a collective overview of how this framework continues to provoke theoretical advances in our conception of the brain in psychiatry. This unique volume is designed to be a comprehensive resource for imaging researchers interested in psychiatry, and for psychiatrists interested in advanced imaging applications.

Neuropsychiatric Disorders

Author : Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 43,6 Mb
Release : 2010-08-09
Category : Medical
ISBN : 9784431538714

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Neuropsychiatric Disorders by Koho Miyoshi,Yasushi Morimura,Kiyoshi Maeda Pdf

Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.

At Risk for Neuropsychiatric Disorders: An Affective Neuroscience Approach to Understanding the Spectrum

Author : Raymond C. K. Chan,Morten L. Kringelbach
Publisher : Frontiers Media SA
Page : 262 pages
File Size : 52,8 Mb
Release : 2016-11-17
Category : Electronic book
ISBN : 9782889450268

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At Risk for Neuropsychiatric Disorders: An Affective Neuroscience Approach to Understanding the Spectrum by Raymond C. K. Chan,Morten L. Kringelbach Pdf

Neuropsychiatric disorders such as schizophrenia, bipolar disorder, depression, anxiety disorders, and other mental disorders constitute about 13% of the global burden of disease surpassing both cardiovascular disease and cancer. The total cost worldwide of these diseases is estimated to exceed 100 million disability-adjusted life years. In order to begin to address this important problem, the present Research Topic brings together a group of leading affective neuroscience researchers to present their state-of-the-art findings using an affective neuroscience approach to investigate the spectrum of neuropsychiatric disorders from patients to those at risk. They focus on different aspects of the emotional and social cognitive disturbances which are core features of neuropsychiatric disorders. While progress has been slow over last couple of decades, we are finally beginning to glimpse some of the underlying neural mechanisms of the emotional and social cognitive disturbances in patients and those at risk. With the technological advances in affective neuroscience and neuroimaging presented in this volume, we hope that progress will be much swifter in the coming years such that we can provide better care for patients and those at risk.

The Human Illnesses

Author : Peter Williamson,John Morgan Allman
Publisher : Oxford University Press, USA
Page : 257 pages
File Size : 48,9 Mb
Release : 2011
Category : Language Arts & Disciplines
ISBN : 9780195368567

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The Human Illnesses by Peter Williamson,John Morgan Allman Pdf

From this perspective, neuropsychiatric disorders are selective failures of brain networks involved in the integration of cognition, affect, and perception. A better understanding of these brain networks will guide the search for environmental factors, genetic correlates, and more effective treatments for these disorders. This volume will be of great interest to psychiatrists, neurologists, psychologists, biologists, and imaging scientists-anyone who has ever wondered what makes the human brain human. --Book Jacket.

The Cognitive-Emotional Brain

Author : Luiz Pessoa
Publisher : MIT Press
Page : 333 pages
File Size : 40,8 Mb
Release : 2013-10-04
Category : Science
ISBN : 9780262019569

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The Cognitive-Emotional Brain by Luiz Pessoa Pdf

A study that goes beyond the debate over functional specialization to describe the ways that emotion and cognition interact and are integrated in the brain. The idea that a specific brain circuit constitutes the emotional brain (and its corollary, that cognition resides elsewhere) shaped thinking about emotion and the brain for many years. Recent behavioral, neuropsychological, neuroanatomy, and neuroimaging research, however, suggests that emotion interacts with cognition in the brain. In this book, Luiz Pessoa moves beyond the debate over functional specialization, describing the many ways that emotion and cognition interact and are integrated in the brain. The amygdala is often viewed as the quintessential emotional region of the brain, but Pessoa reviews findings revealing that many of its functions contribute to attention and decision making, critical components of cognitive functions. He counters the idea of a subcortical pathway to the amygdala for affective visual stimuli with an alternate framework, the multiple waves model. Citing research on reward and motivation, Pessoa also proposes the dual competition model, which explains emotional and motivational processing in terms of their influence on competition processes at both perceptual and executive function levels. He considers the broader issue of structure-function mappings, and examines anatomical features of several regions often associated with emotional processing, highlighting their connectivity properties. As new theoretical frameworks of distributed processing evolve, Pessoa concludes, a truly dynamic network view of the brain will emerge, in which "emotion" and "cognition" may be used as labels in the context of certain behaviors, but will not map cleanly into compartmentalized pieces of the brain.

Neuropsychiatry and Behavioural Neurology Explained

Author : Alex J. Mitchell
Publisher : W B Saunders Company
Page : 525 pages
File Size : 44,9 Mb
Release : 2004
Category : Medical
ISBN : 0702026883

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Neuropsychiatry and Behavioural Neurology Explained by Alex J. Mitchell Pdf

This book provides highly illustrated, clinically focused coverage of neuropsychiatry in one easy to read volume suitable for all clinicians. Its clear visual presentation, including " clinical pointers " and key issues boxes ensures information is easy to access. An evidence based treatment section offers practical guidance on treatment, and principles of assessment and recognition of common signs are included to aid the inexperienced reader. Reviews the principles of neuropsychiatry including the ten maxims of neuropsychiatry � diagnoses of mental state � signs to look for in physical examinations � neuropsychiatric investigations � modes of cognition � and regional cerebral syndromes. Features abundant clinical photographs to facilitate diagnosis. Explains neuropsychiatric disorders related to multifocal disorders, basal ganglia disorders, and much more Presents practical guidance on treatment, principles of assessment, and recognition of common signs. Offers evidence-based guidance for treatment whenever possible.

Disease Control Priorities, Third Edition (Volume 4)

Author : Vikram Patel,Dan Chisholm,Tarun Dua,Ramanan Laxminarayan,Mari'a Lena Medina-Mora,Theo Vos
Publisher : World Bank Publications
Page : 304 pages
File Size : 48,5 Mb
Release : 2016-03-10
Category : Medical
ISBN : 9781464804281

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Disease Control Priorities, Third Edition (Volume 4) by Vikram Patel,Dan Chisholm,Tarun Dua,Ramanan Laxminarayan,Mari'a Lena Medina-Mora,Theo Vos Pdf

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

Modeling Neuropsychiatric Disorders in Laboratory Animals

Author : Kurt Leroy Hoffman
Publisher : Woodhead Publishing
Page : 324 pages
File Size : 40,9 Mb
Release : 2015-08-28
Category : Medical
ISBN : 9780081001066

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Modeling Neuropsychiatric Disorders in Laboratory Animals by Kurt Leroy Hoffman Pdf

Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders

Cognitive deficits in schizophrenia and other neuropsychiatric disorders: Convergence of preclinical and clinical evidence

Author : Ales Stuchlik,Tomiki Sumiyoshi
Publisher : Frontiers Media SA
Page : 285 pages
File Size : 43,8 Mb
Release : 2015-10-23
Category : Electronic book
ISBN : 9782889196791

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Cognitive deficits in schizophrenia and other neuropsychiatric disorders: Convergence of preclinical and clinical evidence by Ales Stuchlik,Tomiki Sumiyoshi Pdf

Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., abstract thinking, decision-making, attention, and several types of memory. Such deficits significantly disrupt quality of life and daily functioning of patients. Cognitive deficits in neuropsychiatric diseases are associated with alterations of brain morphology and function, and are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, i.e. measurable phenotypes linking these disaeses with discrete heritable and reproducible traits. This points to the importance of elucidating these endophenotypes in translational studies. Animal models may not mimic the full spectrum of clinical symptoms, but may act as analogies of particular behaviors or other pathological outcomes. They are useful to search for the etiology of particular psychiatric illnesses and novel therapeutics. Moreover, several behavioral tests to measure cognitive performance in rodents and other species have been implemented. The primary focus of the present topic is to provide up-to-date information on cognitive deficits of neuropsychiatric disorders, such as schizophrenia. This Research Topic also delineates future directions for translational studies aimed at developing novel treatments/interventions of cognitive disturbances.

The Neuropsychology of Mental Illness

Author : Stephen J. Wood,Nicholas B. Allen,Christos Pantelis
Publisher : Cambridge University Press
Page : 465 pages
File Size : 47,5 Mb
Release : 2009-10
Category : Medical
ISBN : 9780521862899

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The Neuropsychology of Mental Illness by Stephen J. Wood,Nicholas B. Allen,Christos Pantelis Pdf

Describes neuropsychological approaches to the investigation, description, measurement and management of a wide range of mental illnesses.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

Author : André Brunoni,Michael A. Nitsche,Colleen Loo
Publisher : Springer
Page : 772 pages
File Size : 51,9 Mb
Release : 2021-10-13
Category : Medical
ISBN : 3030761355

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Transcranial Direct Current Stimulation in Neuropsychiatric Disorders by André Brunoni,Michael A. Nitsche,Colleen Loo Pdf

The 2nd edition of this book incorporates the tremendous clinical advances that have occurred in the field of transcranial direct current stimulation (tDCS) over the past 5 years. Since the 1st edition was published, the clinical use of tDCS has moved from its infancy, and is now in a thrilling new phase with numerous possibilities as well as challenges. tDCS is a technique that excels in terms of safety and tolerability, and within a few years, novel technological developments will allow its use at home. At the same time, large, phase III trials have been exploring the clinical efficacy of tDCS, the results of which have been published in leading journals such as the New England Journal of Medicine and JAMA Psychiatry. This 2nd edition summarizes the state of the art of the field. Written by leading experts in the field, the book is divided into 5 parts: Introduction and Mechanisms of Action; Research Methods; tDCS in the life cycle; Applications of tDCS in neuropsychiatric disorders (further divided into Psychiatry and Neurology); and The clinical use of tDCS. It also includes several new chapters, covering topics such as precision stimulation of tDCS; combination of tDCS with different neuroimaging modalities; and use of tDCS in new clinical conditions. Moreover, all chapters have been rewritten and updated. This book will be of significant interest to psychiatrists, neurologists and neuroscientists new to the field as well as those with a background in tDCS who want to increase their understanding of particular psychiatric conditions.

Oxford Textbook of Neuropsychiatry

Author : Niruj Agrawal,Rafey Faruqui,Mayur Bodani
Publisher : Oxford University Press, USA
Page : 601 pages
File Size : 54,9 Mb
Release : 2020-08-24
Category : Medical
ISBN : 9780198757139

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Oxford Textbook of Neuropsychiatry by Niruj Agrawal,Rafey Faruqui,Mayur Bodani Pdf

New from Oxford Textbooks in Psychiatry, the Oxford Textbook of Neuropsychiatry bridges the gap between general psychiatric textbooks and reference texts in neuropsychiatry. Divided into four sections, it covers core knowledge and skills for practice in all psychiatric disciplines, with key information for training in neuropsychiatry.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Author : Michael S. Ritsner
Publisher : Springer Science & Business Media
Page : 233 pages
File Size : 40,5 Mb
Release : 2009-04-24
Category : Medical
ISBN : 9789048122981

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The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes by Michael S. Ritsner Pdf

Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.