Vaccinology And Methods In Vaccine Research

Author : Rebecca Ashfield,Angus Nnamdi Oli,Charles Esimone,Linda Onyeka Anagu
Publisher : Academic Press
Page : 337 pages
File Size : 49,6 Mb
Release : 2022-03-10
Category : Medical
ISBN : 9780323914383

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Vaccinology and Methods in Vaccine Research by Rebecca Ashfield,Angus Nnamdi Oli,Charles Esimone,Linda Onyeka Anagu Pdf

Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field. It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice. Addresses how to design a vaccine for an emerging disease, from a practical point-of -view, with chapters written by scientists who are grappling with these questions Provides new approaches to vaccine development. including vaccine targeting and virus-like-particle vaccines Gives up-to-date information and methodologies in use for vaccine adjuvants

Author : W. John W. Morrow,Nadeem A. Sheikh,Clint S. Schmidt,D. Huw Davies
Publisher : John Wiley & Sons
Page : 552 pages
File Size : 54,5 Mb
Release : 2012-06-12
Category : Medical
ISBN : 9781118345344

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Vaccinology by W. John W. Morrow,Nadeem A. Sheikh,Clint S. Schmidt,D. Huw Davies Pdf

Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.

Author : Sunil Thomas
Publisher : Unknown
Page : 873 pages
File Size : 53,9 Mb
Release : 2016
Category : Vaccines
ISBN : 1493933876

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Vaccine Design by Sunil Thomas Pdf

Author : Fabio Bagnoli,Rino Rappuoli
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 41,8 Mb
Release : 2015
Category : Medical
ISBN : 1910190039

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Advanced Vaccine Research by Fabio Bagnoli,Rino Rappuoli Pdf

Since the first edition of this book, the field of vaccinology has advanced significantly. The application of new sophisticated omics technologies and the use of pioneering approaches have yielded a wealth of new data. This new book aims to distill the most important new findings to provide a timely overview of the field. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion

Author : M. Elizabeth Halloran,Ira M. Longini, Jr.,Claudio J. Struchiner
Publisher : Springer Science & Business Media
Page : 390 pages
File Size : 40,5 Mb
Release : 2009-10-27
Category : Medical
ISBN : 9780387686363

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Design and Analysis of Vaccine Studies by M. Elizabeth Halloran,Ira M. Longini, Jr.,Claudio J. Struchiner Pdf

As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.

Author : Matthias Giese
Publisher : Springer
Page : 373 pages
File Size : 50,8 Mb
Release : 2016-03-11
Category : Medical
ISBN : 9783319258324

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Introduction to Molecular Vaccinology by Matthias Giese Pdf

This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

Author : Lars Hangartner,Dennis R. Burton
Publisher : Springer Nature
Page : 180 pages
File Size : 50,5 Mb
Release : 2020-09-01
Category : Medical
ISBN : 9783030580049

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Vaccination Strategies Against Highly Variable Pathogens by Lars Hangartner,Dennis R. Burton Pdf

Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine.

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 570 pages
File Size : 47,8 Mb
Release : 2011-12-30
Category : Science
ISBN : 9780309219396

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The Science and Applications of Synthetic and Systems Biology by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Author : Gregg N. Milligan,Alan D. T. Barrett
Publisher : John Wiley & Sons
Page : 404 pages
File Size : 43,8 Mb
Release : 2015-02-16
Category : Medical
ISBN : 9780470656167

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Vaccinology by Gregg N. Milligan,Alan D. T. Barrett Pdf

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Author : Sunil Thomas
Publisher : Springer Nature
Page : 702 pages
File Size : 43,6 Mb
Release : 2021-12-16
Category : Science
ISBN : 9781071618844

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Vaccine Design by Sunil Thomas Pdf

This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.

Author : Parag Kolhe,Satoshi Ohtake
Publisher : Elsevier
Page : 386 pages
File Size : 43,9 Mb
Release : 2021-09-08
Category : Business & Economics
ISBN : 9780128143575

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Practical Aspects of Vaccine Development by Parag Kolhe,Satoshi Ohtake Pdf

Formulation, Development and Manufacturing of Vaccines: The Practical Aspects provides an industry perspective on vaccine product development and manufacture that covers their formulation development, manufacture and delivery/in-use considerations of vaccine production. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and its challenges. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges, including the wide range of vaccine components that may comprise proteins, polysaccharides, protein-polysaccharide conjugates, adjuvants, etc. and the varying stability and behavior of solution- and suspension-based systems. This book is an essential resource for formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students. Includes formulation considerations for various vaccine types, including proteins, polysaccharides, conjugates and live vaccines Considers process development for solution, suspension and lyophilized products Explores the future potential of vaccines, including multi-component vaccines and novel delivery mechanisms/devices

Author : National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications
Publisher : National Academies Press
Page : 118 pages
File Size : 40,8 Mb
Release : 2001-07-11
Category : Science
ISBN : 9780309075558

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Opportunities in Biotechnology for Future Army Applications by National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications Pdf

This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.

Author : Sunil Thomas
Publisher : Humana
Page : 546 pages
File Size : 48,9 Mb
Release : 2021-12-17
Category : Science
ISBN : 1071618911

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Vaccine Design by Sunil Thomas Pdf

This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.

Author : Darren R. Flower,Yvonne Perrie
Publisher : Springer Science & Business Media
Page : 316 pages
File Size : 48,7 Mb
Release : 2012-12-09
Category : Medical
ISBN : 9781461450702

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Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines by Darren R. Flower,Yvonne Perrie Pdf

This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.

Author : Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization
Publisher : Unknown
Page : 392 pages
File Size : 45,6 Mb
Release : 2006
Category : Immunization
ISBN : 0660193922

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Canadian Immunization Guide by Canada. Comité consultatif national de l'immunisation,Canada. National Advisory Committee on Immunization Pdf

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.